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| 1 | 赤泥—煤矸石基公路路面基层材料的耐久与环境性能显示文摘以拜耳法赤泥、煤矸石和粉煤灰等工业固废为基本原料在实验室制备了一种公路路面基层材料,并研究了其力学性能、耐久性能和环境性能.通过开展干湿循环以及冻融循环试验研究了该公路路面基层材料的耐久性能,并利用ICP浸出试验和放射性检测研究其环境性能.结果表明,赤泥-煤矸石基路面基层材料赤泥和煤矸石掺量之和75%、固废总掺量97%时,7 d养护后无侧限抗压强度达到6 MPa以上;经过20个干湿循环后,矿渣掺量为5%的路面基层试块强度为5.98 MPa,满足国家标准;经过5个冻融循环后,路面基层材料的7 d抗压强度仍然达到6.89 MPa,具有良好的耐久性能.浸出试验结果显示,浸出液中Na+浓度均符合国家饮用水标准,同时浸出液中Zn、Hg、Cu、Pb、Ni等重金属均未检测出;放射性试验结果表明,试验所用纯赤泥的放射性符合相应的国家标准.通过对该路面基层材料进行固碱分析以及能谱分析发现,硅铝体系能有效固结钠离子.此公路路面基层材料具有良好的环境效益和社会效益,拓宽了路面基层材料的选材范围. | 刘晓明 唐彬文 尹海峰 Emile Mukiza | 2018 | 工程科学学报2018，40，4： | 36 |
| 2 | Chronology of ultrahigh-pressure metamorphism in the Dabie Mountains and Su-Lu terrane: I. Sm-Nd isotope system显示文摘If the protolith of coesite-bearing eclogite was gabbro, it could undergo ultrahigh-pressure metamorphism under dry condition. In this case, the Hocking temperatures of those minerals could be higher, so that Nd isotope disequilibrium between minerals could be observed. If the protolith of coesite-bearing edogite was metabasalt, amphiboles in the metabasalt were decomposed during ultrahigh-pressure metamorphism and released water. Thus Nd isotope compositions between the minerals were in equilibrium because the blocking temperatures of those minerals could he lower. The secondary alteration and fluid-rock interaction in high-pressure are major problems for Sm-Nd dating of eclogite. The reliable Sm-Nd isotopic ages of coesite-bearing eclogite from the Dabie Mountains and Su-Lu terrane range from 221 to 232 Ma. They are slightly lower, but very close to the peak metamorphic ages of the eclogites. The cold eclogite from the Sujiahe complex could be oceanic subduction origin in the Paleozoic. | 李曙光 肖益林 葛宁洁 陈移之 Emil Jagoutz | 1996 | Science China Earth Sciences1996，39，6： | 27 |
| 3 | 大别山俯冲陆壳的再循环——地球化学证据显示文摘大别山超高压榴辉岩与邻区新生代大陆玄武岩的地球化学对比研究表明,碰撞造山带俯冲陆壳可以再循环进入软流圈地幔,并形成上地幔的EM Ⅰ富集端元它与交代富集不相容元素的岩石圈地幔不同,具有低Rb/Ba和La/Yb的特征.位于大别山和苏-鲁超高压变质带之间的嘉山具有EM Ⅰ特征的新生代大陆玄武岩可能就与大别造山带俯冲陆壳再循环有关. | 李曙光 聂永红 肖益林 郑永飞 Emil Jagoutz | 1997 | 中国科学(D辑)1997，27，5： | 22 |
| 4 | Evolution of transanal total mesorectal excision for rectal cancer:From top to bottom显示文摘The gold standard for curative treatment of locally advanced rectal cancer involves radical resection with a total mesorectal excision(TME). TME is the most effective treatment strategy to reduce local recurrence and improve survival outcomes regardless of the surgical platform used. However, there are associated morbidities, functional consequences, and quality of life(QoL) issues associated with TME; these risks must be considered during the modern-day multidisciplinary treatment for rectal cancer. This has led to the development of new surgical techniques to improve patient, oncologic, and QoL outcomes. In this work, we review the evolution of TME to the transanal total mesorectal excision(TaTME) through more traditional minimally invasive platforms. The review the development, safety and feasibility, proposed benefits and risks of the procedure, implementation and education models, and future direction for research and implementation of the TaTME in colorectal surgery. While satisfactory short-term results have been reported, the procedure is in its infancy, and long term outcomes and definitive results from controlled trials are pending.As evidence for safety and feasibility accumulates,structured training programs to standardize teaching,training, and safe expansion will aid the safe spread of the TaTME. | Sameh Hany Emile F Borja de Lacy Deborah Susan Keller Beatriz Martin-Perez Sadir Alrawi Antonio M Lacy Manish Chand | 2018 | World Journal of Gastrointestinal Surgery2018，10，3： | 18 |
| 5 | Manipulation of a VEGF-Notch signaling circuit drives formation of functional vascular endothelial progenitors from human pluripotent stem cells显示文摘人的 pluripotent 干细胞(hPSC ) 导出 endothelial 系细胞组成有希望的来源因为在这个竞技场的治疗学的 revascularization,而是进步被临床上可伸缩的区别协议和在移植之上与宿主发行量集成的一个功能的容器网络的低效的形成的缺乏妨碍了。在绿的地方,使用一根人的胚胎的干细胞记者房间线荧光灯蛋白质表示被 endothelial 驾驶房间特定的 VE-cadherin (VEC ) 倡导者,我们为 > 屏蔽了;60 bioactive 将支持 endothelial 区别,并且发现 BMP4 和 GSK-3β 的那个政府的小分子;在有 VEGF 的一个早阶段和处理的禁止者 -- 在一个以后的阶段表明小径的槽口的 A 和抑制在六天以内导致了 hPSCs 的有效区别到 endothelial 系。这条顺序的途径产生了 >到 endothelial 房间(EC ) 的 hPSCs 的50%变换,明确地 VEC + CD31 + CD34 + CD14 − KDR 在 endothelial 系房间之中展出了更高的 angiogenic 和 clonogenic 增长潜力的高 endothelial 祖先( EP )。药品的抑制或基因槽口发信号击倒,在有 VEGF 的联合 -- 一个处理,经由 KDR + mesodermal 先锋和对成熟 EC 的 EP 的变换的封锁导致了 EP 的有效形成。当移植了进 immunocompromised 老鼠时,产生 EP 成功地与吻合在 vivo 形成了功能的毛状的容器到主人容器。在我们的协议表明电路的这 VEGF-A-Notch 的操作由 12- 导致导出 hPSC 的 EP 的快速的大规模生产到 20 褶层对当前的方法,它可以与与成熟 EC 相比形成能力的优异容器为再生 vascularization 用作一张吸引人的房间人口。 | Makoto Sahara Emil M Hansson Oliver Wemet Kathy O Lui Daniela Spater Kenneth R Chien | 2014 | Cell Research2014，24，7： | 10 |
| 6 | Durability and microstructure analysis of the road base material prepared from red mud and flue gas desulfurization fly ash显示文摘The present study aimed to investigate the durability and microstructure evolution of road base materials(RBM)prepared from red mud and flue gas desulfurization fly ash.The durability testing showed that the strength of RBM with the blast furnace slag addition of 1wt%,3wt%and 5wt%reached 3.81,4.87,and 5.84 MPa after 5 freezing–thawing(F–T)cycles and reached 5.21,5.75,and 6.98 MPa after 20 weting–drying(W–D)cycles,respectively.The results also indicated that hydration products were continuously formed even during W–D and F–T exposures,resulting in an increase of the strength and durability of RBM.The observed increase of macropores(>1μm)after F–T and W–D exposures suggested that the mechanism of RBM deterioration is pore enlargement due to cracks that develop inside their matrix.Moreover,the F–T exposure showed a greater negative effect on the durability of RBM compared to the W–D exposure.The leaching tests showed that sodium and heavy metals were solidified below the minimum requirement,which indicates that these wastes are suitable for use as a natural material replacement in road base construction. | Emile Mukiza Ling-ling Zhang Xiao-ming Liu | 2020 | International Journal of Minerals,Metallurgy and Materials2020，27，4： | 10 |
| 7 | IL-10 and TNF-α promoter haplotypes are associated with childhood Crohn’s disease location显示文摘AIM: To determine the distribution and frequencies of the genotypes and haplotypes of the genes encoding for the glucocorticoid receptor (GR), the tumor necrosis factor (TNF)-α and the interleukin (IL)-10 in childhood Crohn’s disease (CD) and to assess the impact of the corresponding DNA variants on clinical and disease phenotypes. METHODS: Ten variants in GR, TNF-α and IL-10 were genotyped in 113 childhood CD cases and 95 healthy subjects, both of French-Canadian origin. RESULTS: For the GR polymorphisms (R23K and N363S) and IL-10 variants in the 5’flanking region (-1082 G > A, -819 T > C and -592 A > C), no difference was observed in allele and genotype frequencies between CD patients and controls. At the haplotype level, we found three IL-10 haplotypes previously described in Caucasians (GCC, ACC and ATA) and three novel haplotypes only present in IBD patients. When we analyzed the haplotype distribution with the anatomical location of the disease, the GCC haplotype was associated with the colonic and the ACC haplotype with the terminal ileum location, respectively. The genotyping of fi ve polymorphisms in the promoter region of the TNF-α gene (-1031 T > C, -863 A > C, -857 T > C, -308 A > G and -238 A > G) revealed a significant overrepresentation of homozygous -1031 CC among CD patients (OR = 9.9) and an association with the colonic location. For TNF-α, eleven haplotypes were inferred, including two frequent ones, TCCGG and CACGG, which were significantly observed more frequently in controls and cases, respectively.CONCLUSION: This is one of the fi rst studies investigating the association between haplotype structure and disease location in a CD pediatric cohort. Our results will help to increase our understanding of the genetic determinants of childhood CD. | Rocio Sanchez Emile Levy Florin Costea Daniel Sinnett | 2009 | World Journal of Gastroenterology2009，15，30： | 9 |
| 8 | Gardner's syndrome:Genetic testing and colonoscopy are indicated in adolescents and young adults with cranial osteomas:A case report显示文摘We present a case of a 25-year-old female with diagnosed familial adenomatous polyposis and elevated carcinoembryonic antigen with negative family history. The suspicion of Gardner's syndrome was raised because extirpation of an osteoma of the left temporo-occipital region was made 10 years ago. Restorative procto-colectomy and ileal pouch anal anastomosis was made but histology delineated adenocarcinoma of the rectum (Dukes C stage). We conclude that cranial osteomas often precede gastrointestinal manifestations of familial adenomatous polyposis or Gardner's syndrome and such patients should be evaluated with genetic testing followed by colonoscopy if results are positive to prevent the development of colorectal carcinoma. If the diagnosis is positive all family members should be evaluated for familial adenomatous polyposis. | Dubravko Smud Goran Augustin Tihomir Kekez Emil Kinda Mate Majerovic Zeljko Jelincic | 2007 | World Journal of Gastroenterology2007，13，28： | 7 |
| 9 | Investigation of the medium calcium based non-burnt brick made by red mud and fly ash: durability and hydration characteristics显示文摘Red mud is a type of highly alkaline waste residue produced in the process of alumina smelting by the Bayer process.Based on the idea of medium calcium content,solid wastes such as red mud and fly ash were used to prepare non-burnt bricks;and the mass ratio of CaO/SiO2 was selected in the range of 0.88–1.42.Mechanical properties and durability were investigated with a compressive strength test.X-ray diffractometry(XRD),scanning electron microscope(SEM),and Fourier transform infrared spectroscopy(FTIR)techniques were used to characterize the hydration characteristic.The environmental performance was analyzed by Inductively Coupled Plasma Mass Spectrometry(ICP).The results indicated that the mechanical properties and the durability were optimal when the mass ratio of CaO/SiO2 was 1.23.The hydration products were mostly C–S–H gel,ettringite,Na4Ca(Si10All6)O32·12H2O and Ca3Al2(SiO4)(OH)8.They were responsible for the strength development,and the CaO/SiO2 mass ratio of 1.23 had the best polymerized structure.The results of an environmental performance test showed that the heavy metals in the raw materials were well-solidified in the brick.Therefore,this paper provides an effective solution for use of solid wastes in building material. | Ying-tang Xu Bo Yang Xiao-ming Liu Shuai Gao Dong-sheng Li Emile Mukiza Hua-jian Li | 2019 | International Journal of Minerals,Metallurgy and Materials2019，26，8： | 7 |
| 10 | Unmanned aerial vehicles(UAV)for assessment of qualitative classification of Norway spruce in temperate forest stands显示文摘The study investigates the potential of UAV-based remote sensing technique for monitoring of Norway spruce health condition in the affected forest areas.The objectives are:(1)to test the applicability of UAV visible an near-infrared(VNIR)and geometrical data based on Z values of point dense cloud(PDC)raster to separate forest species and dead trees in the study area;(2)to explore the relationship between UAV VNIR data and individual spruce health indicators from field sampling;and(3)to explore the possibility of the qualitative classification of spruce health indicators.Analysis based on NDVI and PDC raster was successfully applied for separation of spruce and silver fir,and for identification of dead tree category.Separation between common beech and fir was distinguished by the object-oriented image analysis.NDVI was able to identify the presence of key indicators of spruce health,such as mechanical damage on stems and stem resin exudation linked to honey fungus infestation,while stem damage by peeling was identified at the significance margin.The results contributed to improving separation of coniferous(spruce and fir)tree species based on VNIR and PDC raster UAV data,and newly demonstrated the potential of NDVI for qualitative classification of spruce trees.The proposed methodology can be applicable for monitoring of spruce health condition in the local forest sites. | Olga Brovkina Emil Cienciala Peter Surový Přemysl Janata | 2018 | Geo-Spatial Information Science2018，21，1： | 6 |
| 11 | 蛀木生物钻刺团水虱是否改变红茄冬红树林的分布形状?显示文摘为了评价东非不同空间尺度(1m尺度~100km尺度)红树林分布区等足类甲壳动物蛀木虫钻刺团水虱(团水虱属)在美国红树红茄冬气生根中出现的情况,进行了野外调查研究。在肯尼亚和坦桑尼亚桑给巴尔岛17个研究区中,有6个区根本没有发现等足类甲壳动物的痕迹。而在等足类甲壳动物出现的其余研究区,美国红树受侵扰频率都很高。位于潮间带下部泥质基底的红茄冬红树,尤其在水道两侧边缘或直接面海的红树,受侵扰现象不但很普遍而且强度大,绝大部分根被毁坏或死亡。而位于潮间带上部泥质或沙质区的红茄冬红树没有发现受等足类甲壳动物侵扰的痕迹。这种情况也同样发生在空间尺度较大的红树林区,而且岛屿红树林与大陆红树林之间没有任何差别。这说明潮间带的沉积特点、水位高度及直接接触潮水是控制钻刺团水虱丰度的主要因素。等足类甲壳动物在决定红茄冬红树在潮间带下部分布范围方面可能扮演着重要角色。由于受钻刺团水虱的侵害,死亡气生根多或气生根根本不发育的红树由于缺少根系支撑而容易倒伏,这种现象最可能发生在泥质潮间带下部水道边沿一带。在泥质潮间带下部常见有倒伏的红树出现,但是这种倒伏现象在潮间带中、上部区却很少见。本文还探讨了红树林的管理问题。 | Jrundur Svavarsson Melckzedeck K.W.Osore Emil ólafsson 陈奎英 | 2002 | AMBIO-人类环境杂志2002，31，7： | 6 |
| 12 | Protective role of PI3-kinase/Akt/eNOS signaling in mechanical stress through inhibition of p38 mitogenactivated protein kinase in mouse lung显示文摘 | Xin-qi PENG Mahendra DAMARLA Jarrett SKIRBALL Stephanie NONAS Xiao-ying WANG Eugenia J HAN Emile J HASAN Xuan CAO Adel BOUEIZ Rachel DAMICO Rubin M TUDER Alfred M SClUTO Dana R ANDERSON Joe GNGARCIA David A KASS Paul M HASSOUN Jun-tian ZHANG | 2010 | Acta Pharmacologica Sinica2010，31，2： | 6 |
| 13 | Recent advances and future directions in preclinical research of argininevasopressin(AVP) receptor blocker conivaptan in the context of stroke显示文摘Stroke is a major cause of mortality and permanent disability.The onset of stroke is followed by life-threatening pathophysiological responses including brain edema,elevation of intracranial pressure,disruption of blood-brain barrier(BBB),brain infarct and permanent tissue damage.Brain edema develops due to accumulation of water in intracellular and extracellular compartments of the brain,which causes an increase in brain volume and elevation | Emil Zeynalov Susan M.Jones | 2016 | Neural Regeneration Research2016，11，3： | 5 |
| 14 | 高氯酸杂环配合物金属盐的激光起爆(英文)显示文摘Several d-metal perchlorate complexes with 3-hydrazino-4-amino-5-R-1,2,4-triazoles as ligands (where R=H, CH3, SH) were investigated. It was shown that SH-group inhibited radical processes of thermal decomposition and burning of the complexes and also increased the thresholds of their Q-switch IR-laser initiation compared with the salts where as R=H, CH3-groups decreased the sensitivity of the metal complexes to laser initiation. | Mikhail A.Ilyushin Igor V.Tselinsky Irina V.Bachurina Emil Ya.Seidov Anatolii S.Kozlov Dmitrii V.Korolev Alexei E.Olenin | 2006 | 含能材料2006，14，6： | 5 |
| 15 | Colonic duplication in an adult who presented with chronic constipation attributed to hypothyroidism显示文摘Gastrointestinal duplications are an uncommon congenital abnormality that manifest before the age of two in 80% of cases. Ileal duplication is the most common while colonic duplication,either cystic or tubular,occurs in 10%-15% of cases and remains asymptomatic and undiagnosed in most cases. Mostly occurring in pediatric patients,colonic duplication is encountered in adults in only a few cases. The most common clinical manifestations are abdominal pain and intestinal obstruction. Rarely,duplications present with signs of acute abdomen or acute bleeding. This study reports a case of colonic duplication in an adult who presented with chronic constipation. Complete diagnostic workup was made on several occasions during the previous eight year period,but no pathology was found and chronic constipation was attributed to hypothyroidism caused by long standing Hashimoto thyroiditis. Multislice CT,performed because of abdominal distension,defined colonic pathology but the definite diagnosis of duplication of the transversal colon was made at operation. The cystic duplication and the adjacent part of the ascending and transversal colon were excised en-block. This study implies that colonic duplication,though uncommon,should be included in the differential diagnosis of chronic constipation even when precipitating factors for constipation,such as hypothyroidism are present. | Tihomir Kekez Goran Augustin Irena Hrstic Dubravko Smud Mate Majerovic Zeljko Jelincic Emil Kinda | 2008 | World Journal of Gastroenterology2008，14，4： | 5 |
| 16 | Effect of silymarin on biochemical indicators in patients with liver disease: systematic review with meta-analysis显示文摘AIM To evaluate the effect of silymarin on the serum levels of alanine aminotransferase(ALT),aspartate aminotransferase(AST) and gamma glutamyl transpeptidase(γGT) in patients with liver diseases. METHODS A systematic review with meta-analysis of ramdomized and controlled clinical trials was performed,evaluating the effects of sylimarin in patients with hepatic diseases,published by January 31,2016. Clinical trials were sought on the basis of The Cochrane Central Register of Controlled Trials in the Cochrane Library,Pub Med/Medline,Scopus,Web of Science,Lilacs and Clinical Trials. The trials with adult and elderly patients of both sexes,with Liver Diseases who took oral silymarin supplementation,as extract or isolated,as well as Silymarin combined with other nutrients,were included. The trials should provide information about the intervention,such as dosages and detailing of the product used,besides the mean and standard deviation of serum levels of ALT,AST and γGT of the baseline and at the end of the intervention.RESULTS An amount of 10904 publications were identified. From those,only 17 were included in the systematic review and 6 in the meta-analysis,according to the used selection criteria. In this meta-analysis,the results indicated a reduction of 0.26 IU/m L(95%CI:-0.46-0.07,P = 0.007) at the level of ALT and 0.53 IU/m L(95%CI:-0.74-0.32,P = 0.000) at the serum levels of AST after using the silymarin,both,statistically significant,but with no clinical relevance. There was no significant change in the γGT levels. Subgroup analyzes were also performed for the biochemical markers in relation to the type of intervention,whether silymarin isolated or associated with other nutrients and the time of intervention(whether ≥ 6 mo or < 6 mo). Significant differences were not found. The evaluated studies presented a high degree of heterogeneity and low methodological quality in the carried out analysis. CONCLUSION Silymarin minimally reduced,but without clinical relevance,the serum levels of ALT and AST. It is necessary to carry out studies with more appropriate methodological designs. | Camila Ribeiro de Avelar Emile Miranda Pereira Priscila Ribas de Farias Costa Rosangela Passos de Jesus Lucivalda Pereira Magalhaes de Oliveira | 2017 | World Journal of Gastroenterology2017，23，27： | 5 |
| 17 | Cardiac papillary fibroelastoma显示文摘Papillary fibroelastoma(PFE)is a primary,histologically benign endocardial neoplasm.Though PFE has long been reported as the second most common primary cardiac neoplasm,it has since pulled ahead of cardiac myxomas,largely due to evolving cardiac imaging modalities.While PFEs are benign histologically,they have the potential for devastating clinical consequences,transient ischemic attack,stroke,myocardial infarction,syncope,pulmonary,and peripheral embolism.Despite increased detection rate,there remains uncertainty regarding etiology,exact prevalence,and clinical management of PFEs.This paucity of information is reflected by the lack of official guidelines on this matter.In this article,we aim to summarize the current state of understanding regarding PFE and discuss areas of ongoing controversy. | Dominika M Zoltowska Edin Sadic Kyeesha Becoats Shreya Ghetiya Aleem Azal Ali Srinivasan Sattiraju Emil Missov | 2021 | Journal of Geriatric Cardiology2021，18，5： | 4 |
| 18 | Bile leakage after loop closure vs clip closure of the cystic duct during laparoscopic cholecystectomy:A retrospective analysis of a prospective cohort显示文摘BACKGROUND Laparoscopic cholecystectomy(LC)is one of the most frequently performed surgical procedures.Cystic stump leakage is an underestimated,potentially life threatening complication that occurs in 1%-6%of the patients.With a secure cystic duct occlusion technique during LC,bile leakage becomes a preventable complication.AIM To investigate the effect of polydioxanone(PDS)loop closure of the cystic duct on bile leakage rate in LC patients.METHODS In this retrospective analysis of a prospective cohort,the effect of PDS loop closure of the cystic duct on bile leakage complication was compared to patients with conventional clip closure.Logistic regression analysis was used to develop a risk score to identify bile leakage risk.Leakage rate was assessed for categories of patients with increasing levels of bile leakage risk.RESULTS Of the 4359 patients who underwent LC,136(3%)underwent cystic duct closure by a PDS loop.Preoperatively,loop closure patients had significantly more complicated biliary disease compared to the clipped closure patients.In the loop closure cohort,zero(0%)bile leakage occurred compared to 59 of 4223(1.4%)clip closure patients.For patients at increased bile leakage risk(risk score≥1)rates were 1.6%and up to 13%(4/30)for clip closure patients with a risk score≥4.This risk increase paralleled a stepwise increase of actual bile leakage complication for clip closure patients,which was not observed for loop closure patients.CONCLUSION Cystic duct closure with a PDS loop during LC may reduce bile leakage in patients at increased risk for bile leakage. | Sandra C Donkervoort Lea M Dijksman Aafke H van Dijk Emile A Clous Marja A Boermeester Bert van Ramshorst Djamila Boerma | 2020 | World Journal of Gastrointestinal Surgery2020，12，1： | 4 |
| 19 | Recurrent anal fistulas: When, why, and how to manage?显示文摘Anal fistula is a commonly encountered anal condition in the surgical practice.Despite being a benign condition,anal fistula remains to represent a surgical challenge,particularly the complex type of fistulas.One of the common complications of anal fistula surgery is the persistence or recurrence of the pathology,both defined as failure of surgery.Recurrent anal fistulas after previous surgery represent an even more challenging problem since they are usually associated with a higher risk of re-recurrence and continence disturbance.The present review aimed to shed light on various aspects of recurrent anal fistulas,including the different definitions of failure after surgery,risk factors of recurrence,problems associated with management of recurrent fistulas,and assessment and treatment of recurrent anal fistulas. | Sameh Hany Emile | 2020 | World Journal of Clinical Cases2020，8，9： | 4 |
| 20 | Potentially mobile phosphorus in Lake Erken sediment显示文摘 | Emil Rydin | 2000 | Water Research2000，，7： | 3 |
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