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| 1 | Drag reduction behavior of hydrolyzed polyacrylamide/xanthan gum mixed polymer solutions显示文摘Partially hydrolyzed polyacrylamide(HPAM)as the main component of slickwater fracturing fluid is a shear-sensitive polymer,which suffers from mechanical degradation at turbulent flow rates.Five different concentrations of HPAM as well as mixtures of polyacrylamide/xanthan gum were prepared to investigate the possibility of improving shear stability of HPAM.Drag reduction(DR)measurements were performed in a closed flow loop.For HPAM solutions,the extent of DR increased from 30%to67%with increasing HPAM concentration from 100 to1000 wppm.All the HPAM solutions suffered from mechanical degradation and loss of DR efficiency over the shearing period.Results indicated that the resistance to shear degradation increased with increasing polymer concentration.DR efficiency of 600 wppm xanthan gum(XG)was 38%,indicating that XG was not as good a drag reducer as HPAM.But with only 6%DR decline,XG solution exhibited a better shear stability compared to HPAM solutions.Mixed HPAM/XG solutions initially exhibited greater DR(40%and 55%)compared to XG,but due to shear degradation,DR%dropped for HPAM/XG solutions.Compared to 200 wppm HPAM solution,addition of XG did not improve the drag reduction efficiency of HPAM/XG mixed solutions though XG slightly improved the resistance against mechanical degradation in HPAM/XG mixed polymer solutions. | Mehdi Habibpour Peter E. Clark | 2017 | Petroleum Science2017，14，2： | 6 |
| 2 | The Molecular Pathogenesis of Osteosarcoma: A Review显示文摘 | Matthew L. Broadhead Jonathan C. M. Clark Damian E. Myers Crispin R. Dass Peter F. M. Choong H. Kovar | 2011 | Sarcoma2011，，： | 4 |
| 3 | 香港九龙大坑东地下蓄水方案数值研究显示文摘香港九龙大坑东地下蓄水方案(Tai Hang Tung Storage Scheme-THTSS)是香港西九龙渠道改善二期计划的一个重要组成部分,其目标是解决香港九龙繁华拥挤、人口稠密的商业中心旺角一带的洪水淹没问题。THTSS即是在经常洪水淹没区域(大坑东和界限街水渠交接处)上游足球场下面建立一个100 000 m3的地下蓄水池。本文建立了一个能处理明渠缓流和急流、封闭管道有压流、侧流堰和渠道汇合处过渡流于一体的一维水力数学模型,用1∶22正态物理模型恒定流下的结果进行验证。数值模型计算了在50年一遇暴雨下,非恒定洪水在不同的侧流堰方案下的流动过程。结合物理模型试验结果,选择最佳的地下蓄水方案。计算结果表明,大坑东地下蓄水方案确实能加强旺角地区地洪水控制能力,并能通过50年一遇暴雨的洪水。 | 匡翠萍 李行伟 陈孝章 Peter Clark Nick Townsend Raymond Siu | 2006 | 水科学进展2006，17，3： | 3 |
| 4 | Symposia Report Immunoglobulin G for the Treatment of Chronic Pain:Report of an Expert Workshop显示文摘背景:慢性疼痛的治疗效果仍不理想。尽管现在治疗慢性疼痛的药物种类较多,但许多患者对疗效仍不满意或诉药物的副作用太大。越来越多的证据表明,免疫系统参与了伤害性和神经病理性慢性疼痛的病理过程。设计:在英国利物浦的专题会议上,专家们出示了免疫系统参与慢性疼痛的证据。近来的研究表明,静脉(IVIg)或皮下(SCIg)注射免疫调节药物——多价免疫球蛋白(Ig G)可缓解外周神经病理性疼痛和其他疼痛性疾病。专题会议讨论了IVIg和SCIg治疗的适应证、效价比及其副作用。结果:Ig G可缓解某些伤害性和神经病理性慢性疼痛,如糖尿病、干燥综合征、纤维肌痛症、复杂性区域疼痛综合征、小儿麻痹后遗症和继发于病理性自身抗体的疼痛。结论:Ig G对某些慢性疼痛具有一定的治疗前景。Ig G是一种相对安全的治疗方法,副作用少而轻,但价格较贵。今后有必要对Ig G治疗顽固性疼痛进行随机对照研究和预测性临床试验。 | Stefano Tamburin Kristian Borg Xavier J. Caro Stefano Jann Alexander J. Clark Francesca Magrinelli Gen Sobue Lars Werhagen Giampietro Zanette Haruki Koike Peter J. Spath Angela Vincent Andreas Goebel | 2014 | 中国疼痛医学杂志2014，20，11： | 3 |
| 5 | Preoperative Nutritional Status Is an Important Predictor of Survival in Patients Undergoing Surgery for Renal Cell Carcinoma显示文摘 | Todd M. Morgan Dominic Tang Kelly L. Stratton Daniel A. Barocas Christopher B. Anderson Justin R. Gregg Sam S. Chang Michael S. Cookson S. Duke Herrell Joseph A. Smith Peter E. Clark | 2011 | European Urology2011，，6： | 2 |
| 6 | Bioassay for estimating the biogenic methane-generating potential of coal samples显示文摘 | Elizabeth J.P. Jones Mary A. Voytek Peter D. Warwick Margo D. Corum Alexander Cohn Joseph E. Bunnell Arthur C. Clark William H. Orem | 2008 | International Journal of Coal Geology2008，，1： | 2 |
| 7 | Frequency of regulatory T cells in renal cell carcinoma patients and investigation of correlation with survival显示文摘 | Richard W. Griffiths Eyad Elkord David E. Gilham Vijay Ramani Noel Clarke Peter L. Stern Robert E. Hawkins | 2007 | Cancer Immunology, Immunotherapy2007，，： | 2 |
| 8 | 连续夺获阈值监测与自动调节起搏器刺激输出——MICRONY SR+起搏器多中心研究显示文摘目的:本研究评价具有心室自动夺获功能的 Microny 起搏器的安全性及功效。方法:自1994年11月至1996年9月欧洲国家的16个医学中心,共有113例植入 Microny 起搏器的患者进入了研究。所有植入的起搏器采用了 Pacesetter 的低极化、双极电极导线(Membrane 1402 T)。患者在出院时及出院后1、3、6、12个月分别进行随访。结果:在植入后1个月的随访中,动态心电图显示所有未夺获的心搏均有后备起搏脉冲(4.5 V/0.49 ms)出现。植入时测试自身 R 波高度为14.7±7.4 mV,刺激除极波高度(ER)为10.2±4.8 mV。这些数值随时间推移保持稳定,但二者无相关性(r=0.29),植入时,由VARIO 功能测试的起搏阈值为0.5±0.2 V,由自动夺获功能测试的阈值为0.6±0.3 V。两种方法测试的起搏阈值在各次随访中相关性较好(r=0.79),平均差异为0.11 V。后备起搏脉冲占起搏刺激的1.1%。发放后备起搏脉冲的原因为未能夺获(7.1%);(伪)融合波(87.0%);ER 感知低下(0.5%)和QRS 感知低下(4.1%)。在自动夺获功能打开时,起搏电流总消耗为1.4 A。结论:本研究证明了自动夺获功能根据当时的起搏阈值安全和可靠地调节起搏器的输出,为患者提供最大的安全性并延长起搏器的使用寿命。 | Malcolm Clarke Bo Liu Hans Schller Ludwig Binner Charles Kennergren Modesto Guerola Peter Weinmann Ole Jorgen Ohm | 1997 | 中华心律失常学杂志1997，1，2： | 2 |
| 9 | A next-generation marker genotyping platform(AmpSeq)in heterozygous crops:a case study for marker-assisted selection in grapevine显示文摘Marker-assisted selection(MAS)is often employed in crop breeding programs to accelerate and enhance cultivar development,via selection during the juvenile phase and parental selection prior to crossing.Next-generation sequencing and its derivative technologies have been used for genome-wide molecular marker discovery.To bridge the gap between marker development and MAS implementation,this study developed a novel practical strategy with a semi-automated pipeline that incorporates trait-associated single nucleotide polymorphism marker discovery,low-cost genotyping through amplicon sequencing(AmpSeq)and decision making.The results document the development of a MAS package derived from genotyping-by-sequencing using three traits(flower sex,disease resistance and acylated anthocyanins)in grapevine breeding.The vast majority of sequence reads(⩾99%)were from the targeted regions.Across 380 individuals and up to 31 amplicons sequenced in each lane of MiSeq data,most amplicons(83 to 87%)had<10%missing data,and read depth had a median of 220–244×.Several strengths of the AmpSeq platform that make this approach of broad interest in diverse crop species include accuracy,flexibility,speed,high-throughput,low-cost and easily automated analysis. | Shanshan Yang Jonathan Fresnedo-Ramíre Minghui Wang Linda Cote Peter Schweitzer Paola Barba Elizabeth M Takacs Matthew Clark James Luby David C Manns Gavin Sacks Anna Katharine Mansfield Jason Londo Anne Fennell David Gadoury Bruce Reisch Lance Cadle-Davidson Qi Sun | 2016 | Horticulture Research2016，3，1： | 2 |
| 10 | Specificity of choline metabolites for in vivo diagnosis of breast cancer using 1 H MRS at 1.5 T显示文摘 | Peter Stanwell Laurence Gluch David Clark Boguslaw Tomanek Luke Baker Bruno Giuffrè Cynthia Lean Peter Malycha Carolyn Mountford | 2005 | European Radiology2005，，5： | 2 |
| 11 | Management of the motherapy-inducednausea,vomiting,oralmucositis,anddiarrhocd显示文摘 | Rohini Sharma Peter tobin Stephen J clark | 2005 | Lancet Oncol2005，6，： | 1 |
| 12 | Mortality and Complications Associated with Laparoscopic Cholecystectomy: A Meta-Analysis显示文摘 | Judy A. Shea Michael J. Healey Jesse A. Berlin John R. Clarke Peter F. Malet Rudolf N. Staroscik J. Sanford Schwartz Sankey V. Williams | 1996 | Annals of Surgery1996，，5： | 1 |
| 13 | Mono-and bidentate coordination of N, Ndialkylated 1,3-propanediamines to cobalt( Ⅲ ) :a structure and spectroscopic study显示文摘 | PETER R CRAIG GEORGE R CLARK BRIAN D PALMER | 1997 | Inorganica Chemica Acta1997，260，： | 1 |
| 14 | 电子技术应用显示文摘 | Peter Clarke | 2008 | 2008，，： | 1 |
| 15 | Visual cues used by ball-rolling dung beetles for orientation显示文摘 | Marcus Byrne Marie Dacke Peter Nordstr?m Clarke Scholtz Eric Warrant | 2003 | Journal of Comparative Physiology A2003，，6： | 1 |
| 16 | The significance and measurement of variability in travel behaviour显示文摘 | Peter Jones Mike Clarke | 1988 | Transportation1988，，1： | 1 |
| 17 | A Field Study of Reflectivity and Z-R Relations Using Vertically Pointing Radars and Disdrometers显示文摘 | Tokay Ali Hartmann Peter Battaglia Alessandro Gage Kenneth S Clark Wallace L Williams Christopher R | 2009 | Journal of Atmospheric and Oceanic Technology2009，，6： | 1 |
| 18 | Growth cone guidance and neuron morphology on micropatterned laminin surfaces显示文摘 | Peter clark S Britland | 1993 | Journal of Cell Science1993，105，1： | 1 |
| 19 | Cutting vehicle e- missions with regenerative braking 显示文摘 | Peter Clarke Tariq Muneer Kevin Cullinane | 2010 | Transportation Research Part D2010，15，3： | 1 |
| 20 | The association of housing density,isolation and tuberculosis in Canadian First Nations communities显示文摘 | Michael Clark Peter Ribena Earl Nowgesicb | 2002 | International Journal of Epidemiology2002，31，： | 1 |
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