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| 1 | Urogenital schistosomiasis and soiltransmitted helminthiasis(STH)in Cameroon:An epidemiological update at Barombi Mbo and Barombi Kotto crater lakes assessing prospects for intensified control interventions显示文摘Background:The crater lakes of Barombi Mbo and Barombi Kotto are well-known transmission foci of schistosomiasis and soil-transmitted helminthiasis having had several important control initiatives previously.To collect contemporary epidemiological information,a cross-sectional survey was undertaken inclusive of:signs and symptoms of disease,individual treatment histories,local water,sanitation and hygiene(WASH)-related factors and malacological surveillance,with molecular characterisation of specimens.Methods:At each lake,a community cross-sectional survey was undertaken using a combination of stool and urine parasitological sampling,and interview with pro-forma questionnaires.A total of 338 children and adults participated.Material from snail and parasite species were characterised by DNA methods.Results:Egg-patent prevalence of urogenital schistosomiasis was 8.7%at Barombi Mbo(all light-intensity infections)and 40.1%at Barombi Kotto(21.2%heavy-intensity infections).Intestinal schistosomiasis was absent.At Barombi Kotto,significantly more women reported signs and symptoms associated with female genital schistosomiasis.While there had been extensive recent improvement in WASH-related infrastructure at Barombi Mbo,water contact risk scores were higher among schistosomiasis-infected participants(P<0.001)and at Barombi Kotto in general(P<0.001).Across both lakes,mean prevalence of STH was very low(6.3%)evidencing an impressive decrease of 79.0%over the last decade;neither Strongyloides stercoralis nor Ascaris lumbricoides were found.A total of 29 freshwater sampling sites were inspected for snails,13 in Barombi Mbo and 16 in Barombi Kotto;water chemistry differed significantly(P<0.0001)between lakes for both mean pH(7.9 v.9.6)and mean conductivity(64.3μS v.202.1μS)respectively.Only two Bulinus camerunensis found on the central island of Barombi Kotto were observed to shed schistosome cercariae,but schistosome DNA was later detected in Bulinus sampled from both lakes as well as in Indoplanorbis exustus,an invasive species from Asia.Conclusions:STH is currently at very low levels while urogenital schistosomiasis is of greatest concern at Barombi Kotto.This assessment highlights a unique opportunity for further study of the epidemiological dynamics at these crater lakes,to evaluate future intensified interventions both in terms of gaining and sustaining control at Barombi Kotto or in moving towards local interruption of transmission of both diseases at Barombi Mbo. | Suzy J.Campbell J.Russell Stothard Faye O’Halloran Deborah Sankey Timothy Durant Dieudonne Eloundou Ombede Gwladys Djomkam Chuinteu Bonnie LWebster Lucas Cunningham EJames LaCourse Louis-Albert Tchuem-Tchuente | 2017 | Infectious Diseases of Poverty2017，6，1： | 4 |
| 2 | Guidelines for diagnosis and management of pediatric food allergy in Japan 显示文摘 | Tokuko M Sankei N M asahiko A | 2007 | Allergol Int2007，56，4： | 1 |
| 3 | The effects of impurities on the ideal tensile strength of silicon显示文摘 | HUANG M SPENCE J C H SANKEY O F | 1994 | Philosophical Magazine a-Physics of Condensed of Matter Structure Defects and Mechanical Properties1994，70，1： | 1 |
| 4 | Electron-energy-loss near-edge structure of Be2C显示文摘 | Disko M M Spence J C H Sankey O F | 1986 | Phys Rev B1986，33，： | 1 |
| 5 | Mortality and Complications Associated with Laparoscopic Cholecystectomy: A Meta-Analysis显示文摘 | Judy A. Shea Michael J. Healey Jesse A. Berlin John R. Clarke Peter F. Malet Rudolf N. Staroscik J. Sanford Schwartz Sankey V. Williams | 1996 | Annals of Surgery1996，，5： | 1 |
| 6 | Geometry and energetics of DNA basepa- irs and triplets from first principles quantum molecular relaxations 显示文摘 | Lewis J P Sankey O F | 1995 | Biophys J1995，69，3： | 1 |
| 7 | Exhaled nitric oxide as a simple assessment of airway hyperresponsiveness in bronchial asthma and chronic cough patients 显示文摘 | Hiroko N Shunsuke S Sankei N | 2003 | J Asthma2003，40，6： | 1 |
| 8 | Electronic structure based molecular-dynamics method for large biological systems: Application to the 10 basepair poly (dG)-poly (dC) DNA double helix显示文摘 | Lewis J P Ordejon P Sankey O F | 1997 | Phys Rev B1997，55，： | 1 |
| 9 | A high-pres- sure liquid chromatographic method for the assay of ketopro- fen in plasma and urine, and its application to determining the urinary excretion of free and conjugated ketoprofen following oral adminastration of orudis to man显示文摘 | KAYE CM SANKEY MG HOLT JE | 1981 | Br J clin Pharmac1981，11，4： | 1 |
| 10 | Study on thermal deformation of machine tool structure estimated by its basic characteristics显示文摘 | HORI Sankei NISHIWAKI Nobuhiko | 1998 | The Japan Society of Mechanical Engineers(C)1998，64，621： | 1 |
| 11 | The Containment of Disc Burst Fragments by Cylindrical Shells显示文摘 | Hagg A C Sankey G O | 1974 | Journal of Engineering for Power Transaction of the ASME1974，96，： | 1 |
| 12 | Microwave oscillations of a nanomagnet driven by a spin-polarized current 显示文摘 | KISELEV S I SANKEY J C KRIVOROTOV I N | 2003 | Nature2003，425，6956： | 1 |
| 13 | Molecular-dynamics determination of electronic and vibrational spectra, and equilibrium structures of small Si clusters 显示文摘 | Sankey O F Niklewski D J | 1989 | Phys Rev B1989，40，： | 1 |
| 14 | Chemical Reactions of Ammonia with Polar and Non-polar Nitride Semiconductor Surfaces显示文摘 | Fritsch J Sankey O F Schmidt K E | 1999 | Surface Science1999，427，： | 1 |
| 15 | Congestive gastropathy and helicobacter pylori: an endoscopic and morphometric study 显示文摘 | McCormick PA Sankey EA Cardin F | 1991 | Gut1991，32，4： | 1 |
| 16 | Microwave oscillations of a nanomagnet driven by a spin-polarized current显示文摘 | KISELEV S I SANKEY J C KRIVOROTOV I N | 2003 | Nature2003，425，6956： | 1 |
| 17 | Is stone radiodensity a useful parameter for predicting outcome of extracorporeal shockwave lithotripsy for stones < or = 2 cm?显示文摘 | Krishnamurthy M S Ferucci P G Sankey N | 2005 | Int Braz J Urol2005，31，1： | 1 |
| 18 | Theoretical study of carotene as a molecular wire 显示文摘 | Li J Tomfohr J K Sankey O F | 2003 | Physica E2003，19，： | 1 |
| 19 | A follow-up study of chronic fatigue syndmmein children and adolesceems:synptom persistence and school absenteeism 显示文摘 | Sankey A Hill CM Brown J | 2006 | Clin Child Psychol Psychiatry2006，11，： | 1 |
| 20 | Estrogen and testosterone have opposing effects on chronic cardiac remodeling and function in mice with myocardial infarction显示文摘 | CAVASIN M A SANKEY S S YU A L | 2003 | Am J Physiol Heart Circ Physioh2003，284，5： | 1 |
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