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| 1 | Phytochrome Signaling in Green Arabidopsis Seedlings: Impact Assessment of a Mutually Negative phyB-PIF Feedback Loop显示文摘reversibly 红的(R)/far-red (FR )-light-responsive phytochrome (phy ) photosensory 系统在第一暴露之上在发芽黑暗的幼苗开始 deetiolation 进程到光,和阴影回避过程在充分,在到 vegetational 的暴露之上的 deetiolated 幼苗遮。到驾驶这些回答的 transcriptional 网络的从激活光的光敏电阻器 conformer (Pfr ) 的细胞内部的发信号小径与 bHLH 抄写因素的一个小亚科包含 Pfr 的直接、物理相互作用,称为的交往 Phy 因素(程序信息文件) ,它导致快速的程序信息文件解朊的降级。另外,有在光成年的幼苗的进一步的复杂性的证据, phyBPIF 相互作用由此相互地导致 phyB 降级,在里面一互相否定,反馈环配置。这里,在光成年的幼苗估计这些对抗活动的相对贡献到网 phenotypic 读出,我们检验了 light-shade-induced 的大小和 pentuple phyBpif1pif3pif4pif5 (phyBpifq ) 的 simulated-shade-induced 回答变异、各种各样的多重 pif 变异的联合。数据( 1 )重申 phyB 是占优势不独占,响应延长连续 R 照耀在 deetiolating 幼苗强加胚轴延伸的抑制的光敏电阻器并且( 2 )出现 PIF 四重唱( PIF1 , PIF3 , PIF4 ,并且 PIF5 )保留并且施加一个双能力在这些条件下面调制胚轴延伸由附随地通过内在的transcriptional规章的活动支持房间延伸,并且通过 feedb 减少phyB禁止的能力在暴露阴影的幼苗, immunoblot 分析证明在 Pfr 层次的强加阴影的减小在许多 PIF3 导致增加,并且变异的分析显示 PIF3 行动,到,与 PIF4 和 PIF5 一起支持胚轴延伸的已知的导致阴影的加速。相反地,尽管四倍的 pifq 异种显示清楚地减少了胚轴延伸与相比响应延长色泽野类型, immunoblot 分析不在变异的幼苗在 phyB 层次检测举起与相比在导致阴影的生长时期的多数期间野类型,并且 phyB 层次要用体力地没越过比较的pif变异的联合与生长显型被相关。这些结果建议 phyB 丰富的程序信息文件反馈调整不在在这些下面的支持程序信息文件的、阴影应答的显型的大小调节的 modulating 起一个主导的作用。在成长在下面的幼苗日报 lightdark 周期,在黑暗经期(End-of-Day-FR (EOD-FR ) 治疗) 的开始的 Pfr 的 FR-pulse-induced 移动相对没有 EOD-FR 治疗导致更长的胚轴并且这效果在 pif 变异的联合被稀释的数据表演测试了。这结果同样显示 PIF 四重唱成员能够内在地在光成年的植物支持胚轴房间延伸,独立于 photoactivated-phyB 丰富的程序信息文件反馈调整的效果。 | Pablo Leivar Elena Monte Megan M. Cohn Peter H. Quail | 2012 | Molecular Plant2012，5，3： | 20 |
| 2 | Recent advances and applications of deep learning methods in materials science显示文摘Deep learning(DL)is one of the fastest-growing topics in materials data science,with rapidly emerging applications spanning atomistic,image-based,spectral,and textual data modalities.DL allows analysis of unstructured data and automated identification of features.The recent development of large materials databases has fueled the application of DL methods in atomistic prediction in particular.In contrast,advances in image and spectral data have largely leveraged synthetic data enabled by high-quality forward models as well as by generative unsupervised DL methods.In this article,we present a high-level overview of deep learning methods followed by a detailed discussion of recent developments of deep learning in atomistic simulation,materials imaging,spectral analysis,and natural language processing.For each modality we discuss applications involving both theoretical and experimental data,typical modeling approaches with their strengths and limitations,and relevant publicly available software and datasets.We conclude the review with a discussion of recent cross-cutting work related to uncertainty quantification in this field and a brief perspective on limitations,challenges,and potential growth areas for DL methods in materials science. | Kamal Choudhary Brian DeCost Chi Chen Anubhav Jain Francesca Tavazza Ryan Cohn Cheol Woo Park Alok Choudhary Ankit Agrawal Simon J.L.Billinge Elizabeth Holm Shyue Ping Ong Chris Wolverton | 2022 | npj Computational Materials2022，，1： | 9 |
| 3 | Best Constants for Moser-Trudinger Inequalities,Fundamental Solutions and One-Parameter Representation Formulas on Groups of Heisenberg Type | COHN William S. | 2002 | Acta Mathematica Sinica,English Series2002，18，2： | 8 |
| 4 | Arterial Stiffness, Vascular Disease, and Risk of Cardiovascular Events显示文摘 | Jay N. Cohn | 2006 | Circulation2006，，5： | 4 |
| 5 | Results of docetaxel plus oxaliplatin (DOCOX) ± cetuximab in patients with metastatic gastric and/or gastroesophageal junction adenocarcinoma: results of a randomized phase 2 study显示文摘 | Donald Richards Darren M. Kocs Alexander I. Spira A. David McCollum Sami Diab Lanny I. Hecker Allen Cohn Feng Zhan Lina Asmar | 2013 | European Journal of Cancer2013，，： | 3 |
| 6 | Omega-3 supplementation and non-alcoholic fatty liver disease: A systematic review and meta-analysis显示文摘 | Helen M. Parker Nathan A. Johnson Catriona A. Burdon Jeffrey S. Cohn Helen T. O’Connor Jacob George | 2011 | Journal of Hepatology2011，，4： | 3 |
| 7 | Qualitative spatial representation and reasoning: an overview 显示文摘 | Cohn A G Hazarika S M | 2001 | Fundamenta Informaticae2001，45，： | 2 |
| 8 | Bioassay for estimating the biogenic methane-generating potential of coal samples显示文摘 | Elizabeth J.P. Jones Mary A. Voytek Peter D. Warwick Margo D. Corum Alexander Cohn Joseph E. Bunnell Arthur C. Clark William H. Orem | 2008 | International Journal of Coal Geology2008，，1： | 2 |
| 9 | 关于导致心脏病终末期因素的新概念显示文摘关于导致心脏病终末期因素的新概念[CohnJN.CardiovascOrugsTher,1995,9:489(英文)]不论其原发病因如何,心脏病总是向前发展的。慢性容量负荷过重如二尖瓣关闭不全,可代偿数年直至左心室出现一些内在因素而进入不可逆转的阶段... | Cohn JN | 1996 | 心血管病学进展1996，17，5： | 2 |
| 10 | Sentinel Lymph Node Mapping of the Gastrointestinal Tract by Using Invisible Light显示文摘 | Edward G. Soltesz Sungjee Kim Sang-Wook Kim Rita G. Laurence Alec M. De Grand Cherie P. Parungo Lawrence H. Cohn Moungi G. Bawendi John V. Frangioni | 2006 | Annals of Surgical Oncology2006，，3： | 2 |
| 11 | 血管扩张剂治疗心力衰竭的未来指向显示文摘近10年来,对心脏衰竭血管扩张剂联合治疗的有利血流动力学效用和作用机理等的研究,取得了进展。未来的指向将是血管收缩新机理的探讨,从而研制新的、理想的血管扩张剂,以取得治疗的新突破。 | Cohn JN 何玉泉 | 1991 | 国外医学(心血管疾病分册)1991，18，6： | 2 |
| 12 | Effect of high temperature lean aging on the performance of Pt, Pd/CeO2 and rare earth/alkaline earth doped Pt,Pd/CeO2 catalysts显示文摘 | Nunan J G Cohn M J Donner J T | 1992 | Catal today1992，14，： | 2 |
| 13 | One thousand minimally invasive mitral valve operations: early outcomes, late outcomes and echocardiographic follow-up显示文摘 | R. Scott McClure Leonidas V. Athanasopoulos Siobhan McGurk Michael J. Davidson Gregory S. Couper Lawrence H. Cohn | 2012 | The Journal of Thoracic and Cardiovascular Surgery2012，，： | 2 |
| 14 | Comprehensive miRNA profiling of surgically staged endometrial cancer显示文摘 | David E. Cohn Muller Fabbri Nicola Valeri Hansjuerg Alder Iouri Ivanov Chang-Gong Liu Carlo M. Croce Kimberly E. Resnick | 2010 | American Journal of Obstetrics and Gynecology2010，，6： | 2 |
| 15 | Exposure to polychlorinated biphenyl (PCB) congeners measured shortly after giving birth and subsequent risk of maternal breast cancer before age 50显示文摘 | Barbara A. Cohn Mary Beth Terry Marj Plumb Piera M. Cirillo | 2012 | Breast Cancer Research and Treatment2012，，1： | 2 |
| 16 | Minimally invasive aortic valve replacement: how does this perform in high-risk patients?显示文摘 | Jan D Schmitto Friedrich W Mohr Lawrence H Cohn | 2011 | Current Opinion in Cardiology2011，，2： | 2 |
| 17 | The acctivation of mononuc ear phagocytes: fact, fancy, and future显示文摘 | Cohn Z A | 1978 | Immunology1978，121，： | 1 |
| 18 | Arterial elasticity as part of a comprehensive assessmen to cardiovascular risk and drug treatment 显示文摘 | Cohn JN DuprezDA Grandits GA | 2005 | Hypertension2005，46，7： | 1 |
| 19 | Overview of the treatment of heart failure显示文摘 | COHN J N | 1997 | Am J Cardiol1997，80，11： | 1 |
| 20 | Effects of subanesthetic doses of ketamine on hemodynamie and immunologic variables in dogs with experimentally induced endotoxemia显示文摘 | DeClue AE Cohn LA Lechner ES | 2008 | Am J Vet Res2008，69，2： | 1 |
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