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| 1 | From pollutant to solution of wastewater pollution: Synthesis of activated carbon from textile sludge for dye adsorption显示文摘Adsorption is an important process in wastewater treatment,and conversion of waste materials to adsorbent offers a solution to high material cost related to the use of commercial activated carbon.This study investigated the adsorption behaviour of Reactive Black 5(RB5)and methylene blue(MB)onto activated carbon produced from textile sludge(TSAC).The activated carbon was synthesized through chemical activation of precursor followed with carbonization at 650°C under nitrogen flow.Effects of time(0–200 min),pH(2–10),temperature(25–60°C),initial dye concentration(0–200 mg·L^(-1)),and adsorbent dosage(0.01–0.15 g)on dye removal efficiency were investigated.Preliminary screening revealed that TSAC synthesized via H_2SO_4activation showed higher adsorption behaviour than TSAC activated by KCl and ZnCl_2.The adsorption capacity of TSAC was found to be 11.98 mg·g^(-1)(RB5)and 13.27 mg·g^(-1)(MB),and is dependent on adsorption time and initial dye concentration.The adsorption data for both dyes were well fitted to Freundlich isotherm model which explains the heterogeneous nature of TSAC surface.The dye adsorption obeyed pseudo-second order kinetic model,thus chemisorption was the controlling step.This study reveals potential of textile sludge in removal of dyes from aqueous solution,and further studies are required to establish the applicability of the synthesized adsorbent for the treatment of waste water containing toxic dyes from textile industry. | Syieluing Wong Nurul Atiqah Najlaa Yac'cob Norzita Ngadi Onn Hassan Ibrahim M.Inuwa | 2018 | Chinese Journal of Chemical Engineering2018，26，4： | 16 |
| 2 | Poor performance of the modified early warning score for predicting mortality in critically ill patients presenting to an emergency department显示文摘BACKGROUND:This study was undertaken to validate the use of the modified early warning score(MEWS) as a predictor of patient mortality and intensive care unit(ICU)/ high dependency(HD)admission in an Asian population.METHODS:The MEWS was applied to a retrospective cohort of 1 024 critically ill patients presenting to a large Asian tertiary emergency department(ED) between November 2006 and December2007.Individual MEWS was calculated based on vital signs parameters on arrival at ED.Outcomes of mortality and ICU/HD admission were obtained from hospital records.The ability of the composite MEWS and its individual components to predict mortality within 30 days from ED visit was assessed.Sensitivity,specificity,positive and negative predictive values were derived and compared with values from other cohorts.A MEWS of ≥4 was chosen as the cut-off value for poor prognosis based on previous studies.RESULTS:A total of 311(30.4%) critically ill patients were presented with a MEWS ≥4.Their mean age was 61.4 years(SD 18.1) with a male to female ratio of 1.10.Of the 311 patients,53(17%)died within 30 days,64(20.6%) were admitted to ICU and 86(27.7%) were admitted to HD.The area under the receiver operating characteristic curve was 0.71 with a sensitivity of 53.0%and a specificity of 72.1%in addition to a positive predictive value(PPV) of 17.0%and a negative predictive value(NPV)of 93.4%(MEWS cut-off of ≥4) for predicting mortality.CONCLUSION:The composite MEWS did not perform well in predicting poor patient outcomes for critically ill patients presenting to an ED. | Le Onn Ho Huihua Li Nur Shahidah Zhi Xiong Koh Papia Sultana Marcus Eng Hock Ong | 2013 | World Journal of Emergency Medicine2013，4，4： | 12 |
| 3 | 内皮-氧化氮合酶基因多态性与糖尿病肾病关系的研究显示文摘目的 探讨内皮一氧化氮合酶(eNOS)基因内含子4的多态性与糖尿病肾病的关系,以及其在中国人、马来西亚人和印度人中的分布。方法 选择258例病程在10年以上的2型糖尿病患者作为观察对象,其中中国人150例、马来西亚人71例、印度人37例。从患者全血中提取DNA,然后,进行聚酶链反应(PCR)、克隆及测序。结果 以往认为该基因有2种等位基因(a和b),而本研究发现3种等位基因,并对第3种多态(等位基因c)基因进行了序列分析;统计分析显示,等位基因a、b和c均与糖尿病肾病无显著相关性。结论 eNOS基因内含子4上的多态性有3种等位基因;该基因多态性与糖尿病肾病无显著相关性。 | 廖琳 赵家军 Lim Min Chen Chan Shzu-Wei Lee Kok Onn | 2004 | 中华检验医学杂志2004，27，5： | 7 |
| 4 | Viral hepatitis prevalence in patients with active and latent tuberculosis显示文摘AIM: To assess the prevalence of hepatitis B virus(HBV) and hepatitis C virus(HCV) infection and association with drug induced liver injury(DILI) in patients undergoing anti-tuberculosis(TB) therapy.METHODS: Four hundred and twenty nine patients with newly diagnosed TB- either active disease or latent infection- who were due to commence antiTB therapy between September 2008 and May 2011 were included. These patients were prospectively tested for serological markers of HBV, HCV and human immunodeficiency virus(HIV) infections- hepatitis B core antigen(HBc Ag), hepatitis B surface antigen(HBs Ag), hepatitis B e antigen, Ig G and Ig M antibody to HBc Ag(anti-HBc), HCV Ig G antibody and HIV antibody using a combination of enzyme-linked immunosorbent assay, Western blot assay and polymerase chain reaction techniques. Patients were reviewed at least monthly during the TB treatment initiation phase. Liver function tests were measured prior to commencement of antiTB therapy and 2-4 wk later. Liver function tests were also performed at any time the patient had significant nausea, vomiting, rash, or felt non-specifically unwell. Fisher's exact test was used to measure significance in comparisons of proportions between groups. A P value of less than 0.05 was considered statistically significant.RESULTS: Of the 429 patients, 270(62.9%) had active TB disease and 159(37.1%) had latent TB infection. 61(14.2%) patients had isolated anti-HBc positivity, 11(2.6%) were also HBs Ag positive and 7(1.6%) were HCV-antibody positive. 16/270 patients with active TB disease compared to 2/159 patients with latent TB infection had markers of chronic viral hepatitis(HBs Ag or HCV antibody positive; P = 0.023). Similarly the proportion of HBs Ag positive patients were significantly greater in the active vs latent TB infection group(10/43 vs 1/29, P = 0.04). The prevalence of chronic HBV or HCV was significantly higher than the estimated United Kingdom prevalence of 0.3% for each. We found no association between DILI and presence of serological markers of HBV or HCV. Three(5.3%) patients with serological markers of HBV or HCV infection had DILI compared to 25(9.5%) patients without; P = 0.04.CONCLUSION: Viral hepatitis screening should be considered in TB patients. DILI risk was not increased in patients with HBV/HCV. | Hesam Ahmadi Nooredinvand David W Connell Mahmoud Asgheddi Mohammed Abdullah Marie O'Donoghue Louise Campbell Melissa I Wickremasinghe Ajit Lalvani Onn Min Kon Shahid A Khan | 2015 | World Journal of Gastroenterology2015，21，29： | 7 |
| 5 | Inverse changes in plasma tetranectin and titin levels in patients with type 2 diabetes mellitus: a potential predictor of acute myocardial infarction?显示文摘使用 biomarkers 预言尖锐心肌的梗塞(AMI ) 的早干预将有效地减少全球心脏病发生,特别地在有类型 2 糖尿病 mellitus (T2DM ) 的高风险的病人之中。试图由检测识别潜在的 biomarkers 的这研究在没有 AMI,与那些比较跟随 AMI 的发作的 T2DM 病人在血浆蛋白质的层次变化。没有 AMI 的志愿者 T2DM 病人(控制;n=10 ) 并且有 AMI (n=10 ) 的 T2DM 病人被招募。从这些病人的血浆样品与在二个组之间的水平变化为蛋白质经由二维的胶化电气泳动(2DE ) 被评估到屏幕。胶化图象上的许多点用 Progenesis SameSpots 被分析并且使分析遭到了到假发现率(FDR ) 。有至少 1.5 褶层的统计上重要的变化的蛋白质点为集体 spectrometry (MS ) 被选择分析。由于强壮的心脏的连接, tetranectin 和 titin 被 enzymelinked immunosorbent 试金(ELISA ) 评估。在二个组之间的调整 P 值和褶层变化与显著地改变的丰富导致了 34 个蛋白质点的鉴定。在 MS 分析之上, 17 血浆蛋白质被识别:tetranectin, titin, clusterin, haptoglobin, myosin-13,锌 fnger 蛋白质 445, DNA 修理蛋白质 RAD50,浆液白朊, apolipoprotein A-IV, caspase-6, aminoacyl tRNA synthase 复杂交往的多功能的蛋白质 1, serotransferrin,松香油绑定蛋白质 4, transthyretin, alpha-1-antitrypsin, apolipoprotein A-I 和浆液淀粉的 A。在在控制和 AMI 组之间的 tetranectin 和 titin 的变化的可比较的模式用 ELISA 被证实。在摘要,在血浆的 tetranectin 和 titin 看起来仔细在 T2DM 病人之中与 AMI 的发作被联系并且能为一个心脏的事件的预言被用作潜在的 biomarkers,尽管这在未来的队研究要求确认。 | Mohd Aizat Abdul RAHIM Zubaidah Haji Abdul RAHIM Wan Azman WAN AHMAD Marina Mohd BAKRI Muhammad Dzafir ISMAI Onn Haji HASHIM | 2018 | Acta Pharmacologica Sinica2018，39，7： | 4 |
| 6 | Enhancement of norfloxacin solubility via inclusion complexation with β-cyclodextrin and its derivative hydroxypropyl-β-cyclodextrin显示文摘The objectives of the study were to investigate the effects of β-cyclodextrin(βCD) and hydroxypropyl-β-cyclodextrin(HPβCD) on the solubility and dissolution rate of norfloxacin prepared using three different methods, at drug to cyclodextrin weight ratios of 1:1, 1:2, 1:4 and 1:8. All the methods increased the solubility and dissolution rate of norfloxacin via inclusion complexation with βCD and HPβCD. Norfloxacin was converted from crystalline to amorphous form through inclusion complexation. Solvent evaporation method was the most effective method in terms of norfloxacin solubilisation, while inclusion complex of HPβCD has higher solubility than βCD complex when prepared using the same procedure. | Gabriel Onn Kit Loh Yvonne Tze Fung Tan Kok-Khiang Peh | 2016 | Asian Journal of Pharmaceutical Sciences2016，11，4： | 4 |
| 7 | Voicing by Adapting and Innovating Employees: An Empirical Study on How Personality and Environment Interact to Affect Voice Behavior显示文摘 | Onne Janssen Thea De Vries Anton J. Cozijnsen | 1998 | Human Relations1998，，7： | 2 |
| 8 | 科技创新行为影响机制的研究进展显示文摘从科学思想库建设、高端创新人才培养以及员工创新三个方面探索了影响科技创新行为的社会心理促进机制。作为来自中国科学院学部调研中心的研究群体,通过管理咨询调查和心理学实证研究两种途径,为我国科技创新管理决策提供了一系列研究成果。在科技管理咨询方面,主要是从科学思想库建设的角度,在我国的科技体制改革、战略性新兴产业、院士制度建设和完善方面开展的一系列调查研究。在高端创新人才培养方面,以中科院六大科研院所的科研人员为调研对象,探讨了科研人员的个性特征、领导力建设和团队氛围对科研创新绩效的影响。开展了一系列实证研究,探讨了领导行为和领导成员关系对员工创新的权变管理模型,具体包括了领导认同和领导创新期待的权变管理策略;情绪智力、心理授权和工作满意度对员工创新的促进机制;领导成员交换关系对员工创新行为的权变作用等方面的研究,为构建促进国家创新体系建设的管理决策提供了心理学依据。 | 曲如杰 刘晔 Onne Janssen 时勘 | 2016 | 苏州大学学报(教育科学版)2016，4，2： | 2 |
| 9 | CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes显示文摘 | Luke A. Gilbert Matthew H. Larson Leonardo Morsut Zairan Liu Gloria A. Brar Sandra E. Torres Noam Stern-Ginossar Onn Brandman Evan H. Whitehead Jennifer A. Doudna Wendell A. Lim Jonathan S. Weissman Lei S. Qi | 2013 | Cell2013，，2： | 2 |
| 10 | The disappearance of the resistivity of mercury显示文摘 | Onnes H K | 1911 | Comm Leiden1911，，： | 1 |
| 11 | Bojanc- zyk, Member, IEEE, The hyperbolic singular value decompositi -on and applications 显示文摘 | Ruth Onn Student Member IEEE Allan Stein- hardt Senior Member IEEE and Adam W | 1991 | IEEE Transac- tion On Singal Processing1991，39，7： | 1 |
| 12 | Structural basis for hyperpermeability of tumor vessels in advanced lung adenocarcinoma complicated with pleural effusion显示文摘 | Maya Damianovich Goni Hout Siloni Iris Barshack David A. Simansky Debora Kidron Erel Dar Camila Avivi Amir Onn | 2013 | Clinical Lung Cancer2013，，： | 1 |
| 13 | The hyperbolic singular value decomposition and applications 显示文摘 | ONN R STEINHARDT A O BOJANCZYK A W | 1991 | IEEE Transactions on Signal Processing1991，39，7： | 1 |
| 14 | Tumor Cavitation in Stage I Non Small Cell Lung Cancer: Epidermal Growth Factor Receptor Expression and Prediction of Poor Outcome显示文摘 | Amir Onn Du I1wan Choe Roy S Herbst | 2005 | Radiology2005，237，： | 1 |
| 15 | Endostatin improves radioresponse and blocks tumor revascularization after radiation therapy for A431 xenografts in mice显示文摘 | Satoshi Itasaka Ritsuko Komaki Roy S. Herbst Keiko Shibuya Tomoaki Shintani Nancy R. Hunter Amir Onn Corazon D. Bucana Luka Milas K. Kian Ang Michael S. O’Reilly | 2007 | International Journal of Radiation Oncology, Biology, Physics2007，，： | 1 |
| 16 | Targeted therapy of orthotopic human lung cancer by combined vascular endothelial growth factor and epidermal growth factor receptor signaling blockade显示文摘 | Wu W1 Onn A Isobe T | 2007 | Mol Cancer Ther2007，6，2： | 1 |
| 17 | 显示文摘 | Onn A Levo Y | 1999 | Allergy1999，54，2： | 1 |
| 18 | Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage 1 non-small cell lung cancer 显示文摘 | Onn A Correa A M Gilcrease M etal | 2004 | Clin Cancer Res2004，10，1： | 1 |
| 19 | Leader trust and employee voice: The moderating role of empowering leader behaviors显示文摘 | Gao Liping Janssen Onne Shi Kan | 2011 | The Leadership Quarterly2011，，22： | 1 |
| 20 | The joint impact of perceived influence and supervisor supportiveness on employee innovative behavior 显示文摘 | Onne Janssen | 2005 | Journal of Occupational and Organizational Psychology2005，78，： | 1 |
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