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91篇 您的检索式：作者名="Doudna"

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	题名	作者	年代	出处	被引量
1	The promise and challenge of therapeutic genome editing显示文摘Genome editing,which involves the precise manipulation of cellular DNA sequences to alter cell fates and organism traits,has the potential to both improve our understanding of human genetics and cure genetic disease.Here I discuss the scientific,technical and ethical aspects of using CRISPR(clustered regularly interspaced short palindromic repeats)technology for therapeutic applications in humans,focusing on specific examples that highlight both opportunities and challenges.Genome editing is-or will soon be-in the clinic for several diseases,with more applications under development.The rapid pace of the field demands active efforts to ensure that this breakthrough technology is used responsibly to treat,cure and prevent genetic disease.	Doudna JA	2020	四川生理科学杂志2020，42，1：	30
2	Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression显示文摘	Lei S. Qi Matthew H. Larson Luke A. Gilbert Jennifer A. Doudna Jonathan S. Weissman Adam P. Arkin Wendell A. Lim	2013	Cell2013，，：	2
3	Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression显示文摘	Lei S. Qi Matthew H. Larson Luke A. Gilbert Jennifer A. Doudna Jonathan S. Weissman Adam P. Arkin Wendell A. Lim	2013	Cell2013，，：	2
4	CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes显示文摘	Luke A. Gilbert Matthew H. Larson Leonardo Morsut Zairan Liu Gloria A. Brar Sandra E. Torres Noam Stern-Ginossar Onn Brandman Evan H. Whitehead Jennifer A. Doudna Wendell A. Lim Jonathan S. Weissman Lei S. Qi	2013	Cell2013，，2：	2
5	A three- dimensional view of the molecular machinery of RNA interference显示文摘	Jinek M Doudna J A	2009	Nature2009，457，7228：	1
6	Structure and function of the eukaryotic ribosome:the next frontier 显示文摘	Doudna J A Rath V L	2002	Cell2002，109，2：	1
7	Crystal Structure of the HCV IRES Central Domain Reveals Strategy for Start-Codon Positioning显示文摘	Katherine E. Berry Shruti Waghray Stefanie A. Mortimer Yun Bai Jennifer A. Doudna	2011	Structure2011，，10：	1
8	Structural insights into RNA in- terference显示文摘	Sashital DG Doudna JA	2010	Curr Opin Struct Biol2010，20，1：	1
9	A three-dimensional view of the molec- ular machinery of RNA interference显示文摘	Jinek M Doudna J A	2009	Nature2009，457，7228：	1
10	Structural determinants of RNA recognition and cleavage by Dicer显示文摘	MacRae I J Zhou K Doudna J A	2007	Nature Structural & Molecular Biology2007，14，10：	1
11	RNA-guided genetic silencing systems in bacteria and archaea显示文摘	Wiedenheft B Sternberg S H Doudna J A	2012	Nature2012，482，7385：	1
12	Selection of an RNA molecule that mimics a major auto antigenic epitope of human insulin receptor 显示文摘	Doudna J A Cech T R Sullenger B A		PNAS USA0，92，6：	1
13	Large-scale purifica-tion of a stable form of recombinant tobacco etch virusprotease显示文摘	Lucast L J Baley R T Doudna J A	2001	Bio Techniques2001，30，3：	1
14	Dynamic models for fossil fueled steam units in power system studies 显示文摘	F P de Mello p Anderson J Doudna	1991	IEEE Trans on Power Systems1991，6，2：	1
15	An inhibitory activity in human cells restricts the function of an avian-like influenza virus polymerase 显示文摘	Mehle A Doudna JA	2008	Cell Host Microbe2008，4，2：	1
16	Molecular mechanisms of RNA interference 显示文摘	Wilson RC Doudna JA	2013	Annu Rev Biophys2013，42，：	1
17	Ductgrphy of the breast:technique and findings显示文摘	Gilda Cardenosa Caryn Doudna Eklund GW	1994	AJR1994，162，5：	1
18	RNA-guided genetic silencing systems in bacteria and archaea 显示文摘	Wiedenheft B Sternberg SH Doudna JA	2012	Nature2012，482，7385：	1
19	Biology and applications of CRISPR systems:harnessing nature's toolbox for genome engineering显示文摘	Wright AV Nuez JK Doudna JA	2016	Cell2016，164，12：	1
20	Ductography of the breast:technique and findings显示文摘	Cardenosa G Doudna C Eklund GW	1994	Am J Roentgenol1994，162，：	1

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