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| 1 | Cephalomedullary fixation for femoral neck/intertrochanteric and ipsilateral shaft fractures: surgical tips and pitfalls显示文摘为大腿骨的柄骨折和 ipsilateral 的 ObjectiveSurgical 管理选择近似腿节骨折从单个植入变化到双 implant 固定。特别因为不太软的织物解剖和容忍加速的康复的立即的手术后的重量,在如此的破裂的 Cephalomedullary 固定比另外的技术有相对优点。然而,外科是技术上费力的,有为这固定描述外科的技术的文学的少量。学习的目的是为大腿骨的柄骨折和 ipsilateral 描述 cephalomedullary 固定的外科的技术近似的腿节 fractureMethodsSixteen 盒子(有一个平均数的 10 男性和 6 女性 41.8 变老;年) ipsilateral ,近似腿节和柄破裂被单个阶段的 cephalomedullary 固定在第三级的水平对待在北印度的损伤中心。破裂根据 AO 分类被分类。象对每个骨折模式唯一的技术挑战一样的外科的持续时间的一个 intraoperative 记录最为所有 patientsResultsThe 被保存普通近似大腿骨的模式是在 9 个我们的病人观察的 AO B2.1。当 AO A1.2 在 3 个病人断裂时, AO B2.3 破裂在 4 个病人被看见。四 AO B2.1 和 2 AO B2.3 破裂与 Watson-Jones 途径要求了开的减小。吝啬的起作用的时间在 78 附近;当外科的经验增加了,纪录,它趋于减少。仅仅有 malreduction 的一个盒子,它要求大腿骨的柄骨折和 neck/intertrochanteric 折断的 ipsilateral 的修订 surgery.ConclusionCombination 是为损伤外科医生的一个困难的破裂模式。Cephalomedullary 钉子是一优秀植入因为这断裂,但是避免复杂并发症要求小心的插入。外科与一条明确的学习曲线是技术上费力的。不过,这些破裂的一个多数能被在这篇文章被总结了的后面的基本外科的原则被 singleimplant cephalomedullary 固定通过手术管理。 | Kamal Bali Nitesh Gahlot Sameer Aggarwal Vijay Goni | 2013 | Chinese Journal of Traumatology2013，16，1： | 9 |
| 2 | Management of neglected cervical spine dislocation: a study of six cases显示文摘没有神经病学的赤字的六忽视的颈的脊骨脱臼的一个案例系列,它是管理了 operatively.MethodsThe 学习的 ObjectiveTo 报告从 2010 年 8 月被进行到 2011 年 12 月,案例从医药教育和研究的研究生研究所的门诊部被选择,印度。病人在 30 ~ 50 年的年龄组。所有病人经由前面、以后的 approaches.ResultsDuring 被操作立即的手术后的时期,五(83.33%) 病人们有正常神经病学的地位。有 C 5-C6 subluxation 的(16.67%)病人在在更低的手足的 2/5 和在在 C 6 level.ConclusionThere 下面的上面的手足的 3/5 的水平和马达功率是的 C 6下面与感觉损失开发了神经病学的赤字在对颈的脊骨的忽视的分散注意力的屈曲损害的颅骨拖拉的角色都没为更多推迟比 3 个星期。以后由前面的途径列在后面节省许多时间。如果两条途径将在一样的坐被做,其次地对乐器学没有需要。但是如果上演过程是 planed,以后的稳定被推荐,,有在神经病学的地位的恶化的风险。 | Vijay Goni Nirmal Raj Gopinathan Vibhu Krishnan Rajesh Kumar Avinash Kumar | 2013 | Chinese Journal of Traumatology2013，16，4： | 6 |
| 3 | Arachidyl amido cholanoic acid improves liver glucose and lipid homeostasis in nonalcoholic steatohepatitis via AMPK and mTOR regulation显示文摘BACKGROUND Arachidyl amido cholanoic acid(Aramchol)is a potent downregulator of hepatic stearoyl-CoA desaturase 1(SCD1)protein expression that reduces liver triglycerides and fibrosis in animal models of steatohepatitis.In a phase IIb clinical trial in patients with nonalcoholic steatohepatitis(NASH),52 wk of treatment with Aramchol reduced blood levels of glycated hemoglobin A1c,an indicator of glycemic control.AIM To assess lipid and glucose metabolism in mouse hepatocytes and in a NASH mouse model[induced with a 0.1%methionine and choline deficient diet(0.1MCD)]after treatment with Aramchol.METHODS Isolated primary mouse hepatocytes were incubated with 20μmol/L Aramchol or vehicle for 48 h.Subsequently,analyses were performed including Western blot,proteomics by mass spectrometry,and fluxomic analysis with 13C-uniformly labeled glucose.For the in vivo part of the study,male C57BL/6J mice were randomly fed a control or 0.1MCD for 4 wk and received 1 or 5 mg/kg/d Aramchol or vehicle by intragastric gavage for the last 2 wk.Liver metabolomics were assessed using ultra-high-performance liquid chromatography-time of flight-MS for the determination of glucose metabolism-related metabolites.RESULTS Combination of proteomics and Western blot analyses showed increased AMPK activity while the activity of nutrient sensor mTORC1 was decreased by Aramchol in hepatocytes.This translated into changes in the content of their downstream targets including proteins involved in fatty acid(FA)synthesis and oxidation[PACCα/β(S79),SCD1,CPT1A/B,HADHA,and HADHB],oxidative phosphorylation(NDUFA9,NDUFB11,NDUFS1,NDUFV1,ETFDH,and UQCRC2),tricarboxylic acid(TCA)cycle(MDH2,SUCLA2,and SUCLG2),and ribosome(P-p70S6K[T389]and P-S6[S235/S236]).Flux experiments with 13Cuniformely labeled glucose showed that TCA cycle cataplerosis was reduced by Aramchol in hepatocytes,as indicated by the increase in the number of rounds that malate remained in the TCA cycle.Finally,liver metabolomic analysis showed that glucose homeostasis was improved by Aramchol in 0.1MCD fed mice in a dose-dependent manner,showing normalization of glucose,G6P,F6P,UDP-glucose,and Rbl5P/Xyl5P.CONCLUSION Aramchol exerts its effect on glucose and lipid metabolism in NASH through activation of AMPK and inhibition of mTORC1,which in turn activate FAβ-oxidation and oxidative phosphorylation. | David Fernández-Ramos Fernando Lopitz-Otsoa Laura Delacruz-Villar Jon Bilbao Martina Pagano Laura Mosca Maider Bizkarguenaga Marina Serrano-Macia Mikel Azkargorta Marta Iruarrizaga-Lejarreta Jesús Sot Darya Tsvirkun Sebastiaan Martijn van Liempd Felix M Goni Cristina Alonso María Luz Martínez-Chantar Felix Elortza Liat Hayardeny Shelly C Lu JoséM Mato | 2020 | World Journal of Gastroenterology2020，26，34： | 5 |
| 4 | EVALUATION OF TOPOGRAPHIC INDICES FOR EPHEMERAL-GULLY EROSION ASSESSMENT显示文摘Soil erosion by concentrated flows in agricultural areas is an important process affecting soil losses and landscape degradation. The main factors controlling concentrated flow erosion include the erodibility of materials, soil use and management, climate, and watershed topography. In this paper, two topographic indices, closely related with mathematical expressions suggested by different authors, are used to characterize the influence of watershed topography on gully erosion. The AS1 index is defined as the product of the watershed area and the partial area-weighted average slope. The AS2 index is the product of the watershed area and the length-weighted average swale slope. Using different ephemeral gully erosion databases, a high correlation was found between the topographic indices and the volume of eroded soil. The accuracy of different methods for field measurement of ephemeral gullies was evaluated to ensure that the relation between erosion and topographic indices is not affected by assessment errors. The resulting relation are useful to assess soil losses from gully erosion, to identify the most susceptible watersheds within large areas, and to compare the susceptibility to gully erosion among different catchments. This information also can be important to study the response of natural drainage network systems to different rainfall inputs. | J. CASALI L. M. De SANTISTEBAN J. J. LOPEZ J. V. GIRALDEZ J. POESEN J. NACHTERGAELE M. GONI J. LOIZU M. A. CAMPO | 2005 | International Journal of Sediment Research2005，20，4： | 4 |
| 5 | Elevated insulin-like growth factor 1 receptor, hepatocyte growth factor receptor and telomerase protein expression in mild ulcerative colitis显示文摘 | Ferenc Sipos Orsolya Galamb László Herszényi Béla Molnár Norbert Solymosi Tamás Zágoni Lajos Berczi Zsolt Tulassay | 2008 | Scandinavian Journal of Gastroenterology2008，，3： | 2 |
| 6 | Elbow dislocation with ipsilateral diaphyseal forearm bone fracture: A rare injury report with literature review显示文摘 | Vijay Goni Prateek Behera Umesh Kumar Meena Nirmal raj Gopinathan Narendranadh Akkina R.H.H. Arjun | 2015 | Chinese Journal of Traumatology2015，18，2： | 2 |
| 7 | Proximal tibial and fibular physeal fracture causing popliteal artery injury and peroneal nerve injury: A case report and review of literature显示文摘 | Uday Guled Nirmal Raj Gopinathan Vijay G. Goni Arjun Rhh Rakesh John Prateek Behera | 2015 | Chinese Journal of Traumatology2015，18，4： | 2 |
| 8 | Synthesis of graft-copolymers of acrylic-monomers on amylose-effect of reaction-time显示文摘 | Goni I Gurruchaga M Vazquez B | 1992 | Euro Polym J1992，28，8： | 2 |
| 9 | Record of terrestrial organic matter composition in Amazon fan sediments显示文摘 | GONI M A | 1997 | Proceedings of the Ocean Drilling Program Scientific Resuhs1997，155，51： | 1 |
| 10 | Analysis of resistant starch: a method for foods and food product 显示文摘 | Goni I Carcia-dizl | 1996 | Food Chemistry1996，56，4： | 1 |
| 11 | Oceanic mesoscale eddies as revealed by Lagrangian coherent structures显示文摘 | Beron-Vera F Olascoaga M Goni G | 2008 | Geophysical Research Letters2008，35，12： | 1 |
| 12 | Ocean thermal structure monitoring could aid in the intensity forecast of tropical cyclones 显示文摘 | Goni G J Trinanes J A | 2003 | Eos Trans Amer Geo- phys Union2003，84，： | 1 |
| 13 | Analysis of resistant starch: a method for foods and food products 显示文摘 | Goni I Garcia-Diz L Manas E | 1996 | Food chemistry1996，56，4： | 1 |
| 14 | A reassessment of the sources and importance of land derived organic matter in sur face sediments from the Gulf of Mexico显示文摘 | GONI M A RUTTENBERG K C EGLINTON T I | 1998 | Geochimica et Cosmochimica Acta1998，62，18： | 1 |
| 15 | Open redaction,internal fixation and fibular autongrafting for neglected fracture of the femoral neck显示文摘 | Nagi ON Dhillon MS Goni VG | 1998 | J Bone Joint Surg(Br)1998，80，： | 1 |
| 16 | New freeze-drying method for synthesis 显示文摘 | Palomares V Goni A Muro I G | 2007 | J Power Sources2007，171，： | 1 |
| 17 | Analysis of resistant starch:a method for foods and food produet显示文摘 | Goni I Garela-Diz L Manas E | 1996 | Food Che-mistry1996，56，4： | 1 |
| 18 | Injectable acrylic bone cements for vertebroplasty based on a radiopaque hydroxyapatite : formulation and rheological behaviour 显示文摘 | Hernandez L Gurruchaga M Goni I | 2009 | Mater Sci: Mater Med2009，20，1： | 1 |
| 19 | Analysis of resistant starch:a method for foods and food products显示文摘 | GONI L GARCIA-DIZ E MANAS F | 1999 | Food Chemistry1999，56，4： | 1 |
| 20 | Structural basis for hyperpermeability of tumor vessels in advanced lung adenocarcinoma complicated with pleural effusion显示文摘 | Maya Damianovich Goni Hout Siloni Iris Barshack David A. Simansky Debora Kidron Erel Dar Camila Avivi Amir Onn | 2013 | Clinical Lung Cancer2013，，： | 1 |
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