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| 1 | High Hepatic SCD1 Activity Is Associated with Low Liver Fat Content in Healthy Subjects under a Lipogenic Diet显示文摘 | Günther Silbernagel Marketa Kovarova Alexander Cegan Jürgen Machann Fritz Schick Rainer Lehmann Hans-Ulrich H?ring Norbert Stefan Erwin Schleicher Andreas Fritsche Andreas Peter | 2012 | The Journal of Clinical Endocrinology & Metabolism2012，，12： | 3 |
| 2 | Beta-7 integrin controls enterocyte migration in the small intestine显示文摘AIM:To hypothesize that beta-7 integrin affects cellularmigration of both,lymphocytes and enterocytes.METHODS:The nucleoside analog Brd U was ip injected in beta-7-deficient mice(C57BL/6-Itgbtmlcgn/J)of male gender and age-matched male C57BL/J J mice(wild type)4,20,or 40 h before analysis.The total small intestine was isolated,dissected,and used for morphometrical studies.Brd U-positive epithelial cells were numbered in at least 15 hemi-crypts per duodenum,jejunum,and ileum of each animal.The outer most Brd U-positive cell(cellmax)was determined per hemi-crypt,numerically documented,and statistically analysed.RESULTS:Integrins containing the beta-7-chain were exclusively expressed on leukocytes.In the small intestinal mucosa of beta-7 integrin-deficient mice the number of intraepithelial lymphocytes was drastically decreased.Moreover,the Peyer’s patches of beta-7integrin-deficient mice appeared hypoplastic.In beta-7integrin-deficient mice the location of cellmax was found in a higher position than it was the case for the controls.The difference was already detected at 4 h after Brd U application,but significantly increased with time(40 h after Brd U injection)in all small intestinal segments investigated,i.e.,duodenum,jejunum,and ileum.Migration of small intestinal enterocytes was different between the experimental groups measured by cellmax locations.CONCLUSION:The E-cadherin beta-7 integrin pathway probably controls migration of enterocytes within the small intestinal surface lining epithelial layer. | Elke Kaemmerer Paula Kuhn Ursula Schneider Thomas Clahsen Min Kyung Jeon Christina Klaus Julia Andruszkow Michael Hrer Sabine Ernst Angela Schippers Norbert Wagner Nikolaus Gassler | 2015 | World Journal of Gastroenterology2015，21，6： | 3 |
| 3 | Heparin-induced thrombocytopenia in solid organ transplant recipients: The current scientific knowledge显示文摘Exposure to heparin is associated with a high incidence of immunization against platelet factor 4(PF4)/heparin complexes. A subgroup of immunized patients is at risk of developing heparin-induced thrombocytopenia(HIT), an immune mediated prothrombotic adverse drug effect. Transplant recipients are frequently exposed to heparin either due to the underlying end-stage disease, which leads to listing and transplantation or during the transplant procedure and the perioperative period. To review the current scientific knowledge on antiheparin/PF4 antibodies and HIT in transplant recipients a systematic Pub Med literature search on articles in English language was performed. The definition of HIT is inconsistent amongst the publications. Overall, six studies and 15 case reports have been published on HIT before or after heart, liver, kidney, and lung transplantation, respectively. The frequency of seroconversion for anti-PF4/heparin antibodies ranged between 1.9% and 57.9%. However, different methods to detect anti-PF4/heparin antibodies were applied. In none of the studies HIT-associated thromboembolic events or fatalities were observed. More importantly, in patients with a history of HIT, reexposure to heparin during transplantation was not associated with thrombotic complications. Taken together, the overall incidence of HIT after solid organ transplantation seems to be very low. However, according to the current knowledge, cardiac transplant recipients may have the highest risk to develop HIT. Different alternative suggestions for heparin-free anticoagulation have been reported for recipients with suspected HIT albeit no official recommendations on management have been published for this special collective so far. | Volker Assfalg Norbert Hüser | 2016 | World Journal of Transplantation2016，6，1： | 2 |
| 4 | Low seroprevalence of Helico- bacter pylori infection in patients with stress ulcer bleeding--a pro- spective evaluation of patients on a cardiosurgical intensive care unit显示文摘 | Dieter S Cunter H Norbert S | 2000 | Intensive Care Med2000，26，12： | 1 |
| 5 | Correction of laser scanning intensity data: Data and model-driven approaches显示文摘 | Bernhard H?fle Norbert Pfeifer | 2007 | ISPRS Journal of Photogrammetry and Remote Sensing2007，，6： | 1 |
| 6 | Mono(2-ethylhexyl) phthalate exhibits genotoxic effects in human lymphocytes and mucosal cells of the upper aerodigestive tract in the comet assay显示文摘 | Norbert H Kleinsasser Ulrich A | 2004 | Toxicology Letters2004，148，： | 1 |
| 7 | Degradable biomaterials based on Magnesium corrosion 显示文摘 | Frank W Norbert H Carla V Smadar C Karl U K Regine W Frank F | 2008 | Current Opinion in Solid State and Materials Science2008，12，56： | 1 |
| 8 | Synthesis approaches towards 2-iminothiazolidines:an overview显示文摘 | Matthias D H Norbert D K | 2006 | Tetrahedron2006，62，4： | 1 |
| 9 | Optimization of Pre-and Post-Dispersion Compensation Schemes for 10-Gbits/s NRZ Links Using Standard and Dispersion Compensating Fibers显示文摘 | CHRISTOPHE P NORBERT H | 2000 | IEEE Photonics Technology Letters2000，12，8： | 1 |
| 10 | Fatty acidbinding proteins-insights from genetic manipulations显示文摘 | Norbert H Haunerland S Friedrich S | 2004 | Progress in Lipid Research2004，43，： | 1 |
| 11 | Screen- printed bienzymatic sensor based on sol gel immobilized Nippostrongylus brasiliensis acetylcholinesterase and a cytochrome P450 BM-3 (CYP102- A1) mutant 显示文摘 | Michael W Holger S Norbert H | 2006 | Biosensors and Bioelectronics2006，21，： | 1 |
| 12 | Impact of allogeneic haematopoietic stem cell transplantation in patients with abnl(17p) acute myeloid leukaemia显示文摘 | Brigitte Mohr Johannes Schetelig Kerstin Sch?fer‐Eckart Norbert Schmitz Mathias H?nel Wolf R?sler Norbert Frickhofen Hartmut Link Andreas Neubauer Ulrich Schuler Uwe Platzbecker Jan M. Middeke Gerhard Ehninger Martin Bornh?user Markus Schaich Friedrich St | 2013 | Br J Haematol2013，，： | 1 |
| 13 | SIZING power generation and fuel gapacity of the all-electric warship显示文摘 | NORBERT H D | 2007 | IEEE2007，，1： | 1 |
| 14 | Mammary derived growth inhibitor is not a distinct protein but a mix of heart-type and adipocyte-type fatty acid-binding protein显示文摘 | BERNFRIED S NORBERT B CARSTEN H | 1994 | J Biol Chem1994，271，19： | 1 |
| 15 | Antithymocyte globulin with or without cyclosporin A:11-year follow-up of a randomized trial comparing treatments of aplastic anemia显示文摘 | Norbert F Hermann H Joachim P | 2003 | Blood2003，101，4： | 1 |
| 16 | Cytotoxic and genotoxic effects of resin monomers in human salivar- y gland tissue and lymphocytes as assessed by the single cell micro- gel electrophoresis ( Comet ) assay 显示文摘 | Kleinsasser Norbert H Schmid Katharina Sassen Andrea W | 2006 | Biomater2006，27，9： | 1 |
| 17 | Antithymocyte globulin with or without cyclosporin A:11-year follow-up of arandomized trial comparing treatments of aplastic anemia显示文摘 | Norbert F Hermann H Joachim P | 2003 | BLOOD2003，101，4： | 1 |
| 18 | Fatty acid-binding proteins-insights from genetic manipulations显示文摘 | NORBERT H H FRIEDRICH S | 2004 | Progress in Lipid Research2004，43，： | 1 |
| 19 | Quanticationof fungal DNA by using fluorescence resonance energytransfer and the light cycler system显示文摘 | Juergen L Norbert H Holger H | 2000 | J Clin Microbi-ol2000，38，2： | 1 |
| 20 | Fatty acid-binding proteins-insights from genetic manipulations显示文摘 | NORBERT H HAUNERLAND FRIEDRICH S | 2004 | Progress in Lipid Research2004，43，： | 1 |
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