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| 1 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 2 | Cholesterol crystal binding of biliary immunoglobulin A: visualization by fluorescence light microscopy显示文摘AIM To assess potential contributions of biliary IgA for crystal agglomeration into gallstones, we visualized cholesterol crystal binding of biliary IgA.METHODS Crystal-binding biliary proteins were extracted from human gallbladder bile using lectin affinity chromatography. Biliary IgA was isolated from the bound protein fraction by immunoaffinity chromatography. Pure cholesterol monohydrate crystals were incubated with biliary IgA and fluoresceine isothiocyanate (FITC)-conjugated anti-lgA at 37C. Samples were examined under polarizing and fluorescence light microscopy with digital image processing.RESULTS Binding of biliary IgA to cholesterol monohydrate crystals could be visualized with FITC-conjugated anti-lgA antibodies. Peak fluorescence occurred at crystal edges and dislocations. Controls without biliary IgA or with biliary IgG showed no significant fluorescence.CONCLUSION Fluorescence light microscopy provided evidence for cholesterol crystal binding of biliary IgA. Cholesterol crystalbinding proteins like IgA might be important mediators of crystal agglomeration and growth of cholesterol gallstones by modifying the evolving crystal structures in vivo. | Frank Lammert Stefan Südfeld Norbert Busch Siegfried Matern | 2001 | World Journal of Gastroenterology2001，7，2： | 6 |
| 3 | Global Wheat Head Detection 2021:An Improved Dataset for Benchmarking Wheat Head Detection Methods显示文摘The Global Wheat Head Detection(GWHD)dataset was created in 2020 and has assembled 193,634 labelled wheat heads from 4700 RGB images acquired from various acquisition platforms and 7 countries/institutions.With an associated competition hosted in Kaggle,GWHD_2020 has successfully attracted attention from both the computer vision and agricultural science communities.From this first experience,a few avenues for improvements have been identified regarding data size,head diversity,and label reliability.To address these issues,the 2020 dataset has been reexamined,relabeled,and complemented by adding 1722 images from 5 additional countries,allowing for 81,553 additional wheat heads.We now release in 2021 a new version of the Global Wheat Head Detection dataset,which is bigger,more diverse,and less noisy than the GWHD_2020 version. | Etienne David Mario Serouart Daniel Smith Simon Madec Kaaviya Velumani Shouyang Liu Xu Wang Francisco Pinto Shahameh Shafiee Izzat SATahir Hisashi Tsujimoto Shuhei Nasuda Bangyou Zheng Norbert Kirchgessner Helge Aasen Andreas Hund Pouria Sadhegi-Tehran Koichi Nagasawa Goro Ishikawa Sébastien Dandrifosse Alexis Carlier Benjamin Dumont Benoit Mercatoris Byron Evers Ken Kuroki Haozhou Wang Masanori Ishii Minhajul ABadhon Curtis Pozniak David Shaner LeBauer Morten Lillemo Jesse Poland Scott Chapman Benoit de Solan Frédéric Baret Ian Stavness Wei Guo | 2021 | Plant Phenomics2021，3，1： | 2 |
| 4 | The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years显示文摘 | Mark R Nelson Christine Katlama Julio S Montaner David A Cooper Brian Gazzard Bonaventura Clotet Adriano Lazzarin Knud Schewe Joep Lange Christina Wyatt Sue Curtis Shan-Shan Chen Stephen Smith Norbert Bischofberger James F Rooney | 2007 | AIDS2007，，10： | 2 |
| 5 | Elevated insulin-like growth factor 1 receptor, hepatocyte growth factor receptor and telomerase protein expression in mild ulcerative colitis显示文摘 | Ferenc Sipos Orsolya Galamb László Herszényi Béla Molnár Norbert Solymosi Tamás Zágoni Lajos Berczi Zsolt Tulassay | 2008 | Scandinavian Journal of Gastroenterology2008，，3： | 2 |
| 6 | Revolution in plate osteosynthesis: new internal fixator systems显示文摘 | Michael Schütz Norbert P. Südkamp | 2003 | Journal of Orthopaedic Science2003，，2： | 1 |
| 7 | Study of the phase structure of linear polyethylene by means of small-angle X-ray scattering and Raman spectroscopy 显示文摘 | NORBERT S RUFINA G A LEO M | 1995 | Maeromoleeules1995，28，14： | 1 |
| 8 | Low seroprevalence of Helico- bacter pylori infection in patients with stress ulcer bleeding--a pro- spective evaluation of patients on a cardiosurgical intensive care unit显示文摘 | Dieter S Cunter H Norbert S | 2000 | Intensive Care Med2000，26，12： | 1 |
| 9 | New developments of polymeric dental composites 显示文摘 | Norbert M Ulrich S | 2001 | Dent Mater2001，26，4： | 1 |
| 10 | Emotion, Cognition and Decision Making显示文摘 | Norbert S | 2000 | Cognition and Emotion2000，，4： | 1 |
| 11 | Treatment of severe pulmonary hypertension:A bradykinin receptor 2 agonist B9972 causes reduction of pulmonary artery pressure and fight ventricular hypertrophy显示文摘 | TARASEVICIENE S L SCERBAVICIUS R NORBERT F V | 2005 | Peptides2005，26，8： | 1 |
| 12 | Similar Outcomes for Nail versus Plate Fixation of Three-part Proximal Humeral Fractures显示文摘 | Gerhard Konrad Laurent Audigé Simon Lambert Ralph Hertel Norbert P. Südkamp | 2012 | 2012，，2： | 1 |
| 13 | The R^* -tree: an efficient and robust access method for points and rectangles+显示文摘 | Norbert B Hans-Peter b Ralf S | 1990 | ACM1990，1，： | 1 |
| 14 | Robust system design with built-in soft-error resilience显示文摘 | MITRA S NORBERT S ZHANG M | | 0，，02： | 1 |
| 15 | An automated salt-tracing gauge for flow-velocity measurement 显示文摘 | Olivier P Norbert S Raphael G | 2005 | Earth Surf Process Landforms2005，30，： | 1 |
| 16 | Fatty acidbinding proteins-insights from genetic manipulations显示文摘 | Norbert H Haunerland S Friedrich S | 2004 | Progress in Lipid Research2004，43，： | 1 |
| 17 | Screen- printed bienzymatic sensor based on sol gel immobilized Nippostrongylus brasiliensis acetylcholinesterase and a cytochrome P450 BM-3 (CYP102- A1) mutant 显示文摘 | Michael W Holger S Norbert H | 2006 | Biosensors and Bioelectronics2006，21，： | 1 |
| 18 | Management of malignant hyperthermia: diagnosis and treatment 显示文摘 | Daniel S Stephan J Norbert R | 2014 | Therapeutics and Clinical Risc Management2014，10，： | 1 |
| 19 | Nanostructure evolution of isotropic high-pressure injection-molded UHMWPE during heating source显示文摘 | Wang Zhigang Hsiao Benjamin S Stribeck Norbert | 2002 | Macromolecules2002，35，6： | 1 |
| 20 | Mammary derived growth inhibitor is not a distinct protein but a mix of heart-type and adipocyte-type fatty acid-binding protein显示文摘 | BERNFRIED S NORBERT B CARSTEN H | 1994 | J Biol Chem1994，271，19： | 1 |
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