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| 1 | Assessment of the diagnostic performance and interobserver variability of endocytoscopy in Barrett's esophagus:A pilot ex-vivo study显示文摘AIM:To investigate a classification of endocytoscopy(ECS)images in Barrett’s esophagus(BE)and evaluate its diagnostic performance and interobserver variability.METHODS:ECS was applied to surveillance endoscopic mucosal resection(EMR)specimens of BE ex-vivo.The mucosal surface of specimen was stained with 1%methylene blue and surveyed with a catheter-type endocytoscope.We selected still images that were most representative of the endoscopically suspect lesion and matched with the final histopathological diagnosis to accomplish accurate correlation.The diagnostic performance and inter-observer variability of the new classification scheme were assessed in a blinded fashion by physicians with expertise in both BE and ECS and inexperienced physicians with no prior exposure to ECS.RESULTS:Three staff physicians and 22 gastroenterology fellows classified eight randomly assigned unknown still ECS pictures(two images per each classification)into one of four histopathologic categories as follows:(1)BEC1-squamous epithelium;(2)BEC2-BE without dysplasia;(3)BEC3-BE with dysplasia;and(4)BEC4-esophageal adenocarcinoma(EAC)in BE.Accuracy of diagnosis in staff physicians and clinical fellows were,respectively,100%and 99.4%for BEC1,95.8%and83.0%for BEC2,91.7%and 83.0%for BEC3,and95.8%and 98.3%for BEC4.Interobserver agreement of the faculty physicians and fellows in classifying each category were 0.932 and 0.897,respectively.CONCLUSION:This is the first study to investigate classification system of ECS in BE.This ex-vivo pilot study demonstrated acceptable diagnostic accuracy and excellent interobserver agreement. | Yutaka Tomizawa Prasad G Iyer Louis M Wongkeesong Navtej S Buttar Lori S Lutzke Tsung-Teh Wu Kenneth K Wang | 2013 | World Journal of Gastroenterology2013,19,46: | 2 |
| 2 | Utility of Biomarkers in Prediction of Response to Ablative Therapy in Barrett’s Esophagus显示文摘 | Ganapathy A. Prasad Kenneth K. Wang Kevin C. Halling Navtej S. Buttar Louis–Michel Wongkeesong Alan R. Zinsmeister Shannon M. Brankley Emily G. Barr Fritcher Wytske M. Westra Kausilia K. Krishnadath Lori S. Lutzke Lynn S. Borkenhagen | 2008 | Gastroenterology2008,,: | 2 |
| 3 | Endoscopic and Surgical Treatment of Mucosal (T1a) Esophageal Adenocarcinoma in Barrett’s Esophagus显示文摘 | Ganapathy A. Prasad Tsung Teh Wu Dennis A. Wigle Navtej S. Buttar Louis–Michel Wongkeesong Kelly T. Dunagan Lori S. Lutzke Lynn S. Borkenhagen Kenneth K. Wang | 2009 | Gastroenterology2009,,: | 2 |
| 4 | Central Adiposity is Associated with Increased Risk of Esophageal Inflammation, Metaplasia, and Adenocarcinoma: a Systematic Review and Meta-Analysis显示文摘 | Siddharth Singh Anamay N. Sharma Mohammad Hassan Murad Navtej S. Buttar Hashem B. El-Serag David A. Katzka Prasad G. Iyer | 2013 | Clinical Gastroenterology and Hepatology2013,,: | 1 |
| 5 | Endoscopic and Surgical Treatment of Mucosal (T1a) Esophageal Adenocarcinoma in Barrett’s Esophagus显示文摘 | Ganapathy A. Prasad Tsung Teh Wu Dennis A. Wigle Navtej S. Buttar Louis–Michel Wongkeesong Kelly T. Dunagan Lori S. Lutzke Lynn S. Borkenhagen Kenneth K. Wang | 2009 | Gastroenterology2009,,3: | 1 |
| 6 | Central Adiposity is Associated with Increased Risk of Esophageal Inflammation, Metaplasia, and Adenocarcinoma: a Systematic Review and Meta-Analysis显示文摘 | Siddharth Singh Anamay N. Sharma Mohammad Hassan Murad Navtej S. Buttar Hashem B. El-Serag David A. Katzka Prasad G. Iyer | 2013 | Clinical Gastroenterology and Hepatology2013,,: | 1 |
| 7 | 回肠储袋肛管吻合术后储袋扭转:对其发生率、诊断和治疗结局的系统综述显示文摘背景:结直肠切除加回肠储袋肛管吻合术(IPAA)是难治性溃疡性结肠炎和家族性腺瘤性息肉病的标准外科术式。然而,储袋扭转时有发生,尽管发生率很低。本研究旨在探讨IPAA患者术后储袋扭转的发生率、临床表现和治疗。方法:于2018年8月10日通过医学文献图书馆系统检索已发表的文献,由两名独立的研究人员分别进行文献筛选、数据提取、方法学质量评估。同时,检索美国Mayo Clinic 2008年1月至2018年8月间的电子病历发现了1例储袋扭转病例。结果:一项报道了IPAA长期结局的大样本研究显示,储袋扭转发生率为0.18%(3/1700)。本研究共纳入22例储袋扭转患者进行分析,其中18例原发疾病为溃疡性结肠炎。全组病例中位年龄32岁,女性占73%。IPAA术后出现储袋扭转的中位时间为36个月,出现首发症状至诊断储袋扭转的中位时间为24小时。腹痛是最常报道的症状(76%)。多数病例是经腹部CT作出初步诊断(76%,13/17)。11例患者行内镜治疗,仅1例(9%)成功。20例患者行手术治疗,最常采用的手术方式是储袋固定术和储袋切除术。5例(25%)患者接受了再次IPAA手术。结论:储袋扭转是IPAA术后一种罕见但严重的并发症,出现梗阻症状时应考虑储袋扭转的可能。内镜治疗成功率非常低;如果能早期诊断、早期手术,手术治疗疗效确切。 | Muhammad Jawoosh Samir Haffar Parakkal Deepak Alyssa Meyers Amy L.Lightner David W.Larson Laura H.Raffals MHassan Murad Navtej Buttar Fateh Bazerbachi | 2019 | Gastroenterology Report2019,7,6: | 1 |
| 8 | Distribution of Body Fat and Its Influence on Esophageal Inflammation and Dysplasia in Patients With Barrett’s Esophagus显示文摘 | Eric M. Nelsen Yujiro Kirihara Naoki Takahashi Qian Shi Jason T. Lewis Vikneswaran Namasivayam Navtej S. Buttar Kelly T. Dunagan Ganapathy A. Prasad | 2012 | Clinical Gastroenterology and Hepatology2012,,7: | 1 |
| 9 | A Combination of Esomeprazole and Aspirin Reduces Tissue Concentrations of Prostaglandin E 2 in Patients With Barrett’s Esophagus显示文摘 | Gary W. Falk Navtej S. Buttar Nathan R. Foster Katie L. Allen Ziegler Catherine J. DeMars Yvonne Romero Norman E. Marcon Thomas Schnell Douglas A. Corley Prateek Sharma Marcia R. Cruz–Correa Chin Hur David E. Fleischer Amitabh Chak Kenneth R. DeVault Davi | 2012 | Gastroenterology2012,,4: | 1 |
| 10 | Extent of high-grade dysplasia in Barrett’s esophagus correlates with risk of adenocarcinoma显示文摘 | Navtej S. Buttar Kenneth K. Wang Thomas J. Sebo Darren M. Riehle Krishnawatie K. Krishnadath Lori S. Lutzke Marlys A. Anderson Tanya M. Petterson Lawrence J. Burgart | 2001 | Gastroenterology2001,,7: | 1 |
| 11 | Distribution of Body Fat and Its Influence on Esophageal Inflammation and Dysplasia in Patients With Barrett’s Esophagus显示文摘 | Eric M. Nelsen Yujiro Kirihara Naoki Takahashi Qian Shi Jason T. Lewis Vikneswaran Namasivayam Navtej S. Buttar Kelly T. Dunagan Ganapathy A. Prasad | 2012 | Clinical Gastroenterology and Hepatology2012,,7: | 1 |
| 12 | Factors Associated With Increased Survival After Photodynamic Therapy for Cholangiocarcinoma显示文摘 | Ganapathy A. Prasad Kenneth K. Wang Todd H. Baron Navtej S. Buttar Louis–Michel Wongkeesong Lewis R. Roberts Andrew J. LeRoy Lori S. Lutzke Lynn S. Borkenhagen | 2007 | Clinical Gastroenterology and Hepatology2007,,6: | 1 |
| 13 | Effects of Topical Steroids on Tight Junction Proteins and Spongiosis in Esophageal Epithelia of Patients With Eosinophilic Esophagitis显示文摘 | David A. Katzka Ravikanth Tadi Thomas C. Smyrk Eesha Katarya Anamay Sharma Deborah M. Geno Michael Camilleri Prasad G. Iyer Jeffrey A. Alexander Navtej S. Buttar | 2014 | Clinical Gastroenterology and Hepatology2014,,: | 1 |
| 14 | Predictors of stricture formation after photodynamic therapy for high-grade dysplasia in Barrett’s esophagus <ce:link locator='fx1'/>显示文摘 | Ganapathy A. Prasad Kenneth K. Wang Navtej S. Buttar Louis-Michel Wongkeesong Lori S. Lutzke Lynn S. Borkenhagen | 2007 | Gastrointestinal Endoscopy2007,,1: | 1 |
| 15 | Prevalence and predictors of recurrent neoplasia after ablation of Barrett’s esophagus显示文摘 | Rami J. Badreddine Ganapathy A. Prasad Kenneth K. Wang Louis M. Wong Kee Song Navtej S. Buttar Kelly T. Dunagan Lori S. Lutzke Lynn S. Borkenhagen | 2010 | Gastrointestinal Endoscopy2010,,: | 1 |
| 16 | Feasibility of NOTES omental plug repair of perforated peptic ulcers: results from a clinical pilot trial显示文摘 | Juliane Bingener Erica A. Loomis Christopher J. Gostout Martin D. Zielinski Navtej S. Buttar Louis M. Wong Kee Song Todd H. Baron Leili Shahgholi Ghahfarokhi Elizabeth Rajan | 2013 | Surgical Endoscopy2013,,6: | 1 |
| 17 | Contribution of intraoperative enteroscopy in the management of obscure gastrointestinal bleeding显示文摘 | Michael L. Kendrick Navtej S. Buttar Marlys A. Anderson Lori S. Lutzke Daniela Peia Kenneth K. Wang Michael G. Sarr | 2001 | Journal of Gastrointestinal Surgery2001,,2: | 1 |
| 18 | Persistent Genetic Abnormalities in Barrett’s Esophagus After Photodynamic Therapy显示文摘 | Kausilia K. Krishnadath* Kenneth K. Wang* Ken Taniguchi? Thomas J. Sebo? Navtej S. Buttar* Marlys A. Anderson* Lori S. Lutzke* Wanguo Liu? | 2000 | Gastroenterology2000,,3: | 1 |
| 19 | Contribution of intraoperative enteroscopy in the management of obscure gastrointestinal bleeding显示文摘 | Michael L. Kendrick M.D. Navtej S. Buttar M.D. Marlys A. Anderson Lori S. Lutzke Daniela Peia Kenneth K. Wang M.D. Michael G. Sarr M.D | 2001 | Journal of Gastrointestinal Surgery2001,,2: | 1 |