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| 1 | Early-onset gastric cancer:Learning lessons from the young显示文摘There is by no means a clear-cut pattern of mutations contributing to gastric cancers,and gastric cancer research can be hampered by the diversity of factors that can induce gastric cancer,such as Helicobacter pylori infection,diet,ageing and other environmental factors.Tumours are unquestionably riddled with genetic changes yet we are faced with an unsolvable puzzle with respect to a temporal relationship.It is postulated that inherited genetic factors may be more important in early-onset gastric cancer (EOGC) than in gastric cancers found in older patients as they have less exposure to environmental carcinogens.EOGC,therefore,could provide a key to unravelling the genetic changes in gastric carcinogenesis.Gastric cancers occurring in young patients provide an ideal background on which to try and uncover the initiating stages of gastric carcinogenesis.This review summarizes the literature regarding EOGC and also presents evidence that these cancers have a unique molecular-genetic phenotype,distinct from conventional gastric cancer. | Anya N Milne G Johan A Offerhaus | 2010 | World Journal of Gastrointestinal Oncology2010，2，2： | 3 |
| 2 | The European Cancer Anaemia Survey (ECAS): A large, multinational, prospective survey defining the prevalence, incidence, and treatment of anaemia in cancer patients显示文摘 | Heinz Ludwig Simon Van Belle Peter Barrett-Lee Gunnar Birgeg?rd Carsten Bokemeyer Pere Gascón Paris Kosmidis Maciej Krzakowski Johan Nortier Patrizia Olmi Maurice Schneider Dirk Schrijvers | 2004 | European Journal of Cancer2004，，15： | 2 |
| 3 | A pilot study of colonic B cell pattern in irritable bowel syndrome显示文摘 | Johan Forshammar Stefan Isaksson Hans Strid Per-Ove Stotzer Henrik Sj?vall Magnus Simrén Lena ?hman | 2008 | Scandinavian Journal of Gastroenterology2008，，12： | 1 |
| 4 | Decreasing Time-Trends of Colorectal Cancer in a Large Cohort of Patients With Inflammatory Bowel Disease显示文摘 | Sverre S?derlund Lena Brandt Annika Lapidus Per Karlén Olle Brostr?m Robert L?fberg Anders Ekbom Johan Askling | 2009 | Gastroenterology2009，，5： | 1 |
| 5 | Identification of stem cells in small intestine and colon by marker gene Lgr5 显示文摘 | Barker N Johan H Van Es J H | 2007 | Nature2007，449，7165： | 1 |
| 6 | Black carbon-inclusive modeling approaches for estimating lhe aquatic fate of dibenzop-dioxins and dibenzofurans显示文摘 | Armitage J M Cousins Ian T Persson N Johan | 2008 | Environmental Science & Technology2008，42，10： | 1 |
| 7 | Bone-targeted radium-223 in symptomatic, hormone-refractory prostate cancer: a randomised, multicentre, placebo-controlled phase II study显示文摘 | Sten Nilsson Lars Franzén Christopher Parker Christopher Tyrrell René Blom Jan Tennvall Bo Lennern?s Ulf Petersson Dag C Johannessen Michael Sokal Katharine Pigott Jeffrey Yachnin Michael Garkavij Peter Strang Johan Harmenberg Bj?rg Bolstad ?yvind S Brula | 2007 | Lancet Oncology2007，，7： | 1 |
| 8 | The impact of charging plug-in hybrid electric vehicles on a residential distribution grid显示文摘 | KRISTIEN C N EDWIN H JOHAN D | 2010 | IEEE Trans on Power Systems2010，25，1： | 1 |
| 9 | Black carbon-inclusive modeling approaches for estimating the aquatic fate of dibenzopdioxins and dibenzofurans显示文摘 | Armitage J M Cousins lan T Persson N Johan | 2008 | Environmental Science & Technology2008，42，10： | 1 |
| 10 | Poor prognosis of constitutive γ-H2AX expressing triple-negative breast cancers is associated with telomere length显示文摘 | Anika Nagelkerke Simon JA van Kuijk John W Martens Fred CGJ Sweep Nicoline Hoogerbrugge Johan Bussink Paul N Span | 2015 | Biomark. Med2015，，4： | 1 |
| 11 | Taxonomic characterization and plant colonizing abilities of some bacteria related to Bacillus arnylolique f aciens and Bacillus subtilis 显示文摘 | Oleg N R Christina D Johan M | 2004 | FEMS Microbiology Ecology2004，48，： | 1 |
| 12 | PfEMP1-DBL1α amino acid motifs in severe disease states of Plasmodium fcdciparum malaria显示文摘 | Johan N Danie N Uif R | 2007 | PNAS2007，104，15： | 1 |
| 13 | Dynamic time warping of spectroscopic batch data 显示文摘 | RAMAKER H J ERIC N M JOHAN A W | 2003 | Analytica Chimica Acta2003，498，12： | 1 |
| 14 | A bifunctional TPS–TPP enzyme from yeast confers tolerance to multiple and extreme abiotic-stress conditions in transgenic Arabidopsis显示文摘 | José A. Miranda Nelson Avonce Ramón Suárez Johan M. Thevelein Patrick Dijck Gabriel Iturriaga | 2007 | Planta2007，，6： | 1 |
| 15 | Increased Risk of Primary Sclerosing Cholangitis and Ulcerative Colitis in First-Degree Relatives of Patients With Primary Sclerosing Cholangitis显示文摘 | Annika Bergquist Scott M. Montgomery Shahram Bahmanyar Rolf Olsson ?ke Danielsson Stefan Lindgren Hanne Prytz Rolf Hultcrantz Lars L??f Hanna Sandberg–Gertzén Sven Almer Johan Askling Anna Ehlin Anders Ekbom | 2008 | Clinical Gastroenterology and Hepatology2008，，8： | 1 |
| 16 | Controlling persistent organic pollutants–what next? 1 Correspondence to: Nicole G Weavers, ETAF, European Training and Assessment Foundation, PO Box 182, 6700 AD, Wageningen, The Netherlands. Tel.: +31-317-484924; Fax: +31-317-484941 1显示文摘 | Harry W. Vallack Dick J. Bakker Ingvar Brandt Eva Brostr?m-Lundén Abraham Brouwer Keith R. Bull Clair Gough Ramon Guardans Ivan Holoubek Bo Jansson Rainer Koch Johan Kuylenstierna André Lecloux Donald Mackay Patrick McCutcheon Paolo Mocarelli Rob D.F. Taa | 1998 | Environmental Toxicology and Pharmacology1998，，3： | 1 |
| 17 | The impact of vehicleto-grid on the distribution grid 显示文摘 | Kristien C N Edwin H Johan D | 2011 | Electric Power Systems Research2011，81，1： | 1 |
| 18 | Identification of stem cells in small intestine and colon by marker gene Lgr5 显示文摘 | Barker N van Es Johan H Kuipers J | 2007 | Nature2007，449，7165： | 1 |
| 19 | Biochemical basis for glyphosate tolerance in a bacterium and a plant tissue culture 显示文摘 | Amrhein N Johanning D Schab J | 1983 | FEBS Letter1983，157，1： | 1 |
| 20 | Immunometric assay interference:incidence and prevention显示文摘 | Johan B Kjell N Lars FN | 2002 | Clin Chem2002，48，： | 1 |
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