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| 1 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 2 | Biliary cystadenoma显示文摘The diagnosis of cystadenoma is rare, even more so when located in the extrahepatic bile duct.Unspeciflc clinical signs may lead this pathology to be misdiagnosed.The need for pathological anatomy in order to distinguish cystadenomas from simple biliary cysts is crucial.The most usual treatment nowadays is resection of the bile duct, together with cholecystectomy and Roux-en-Y reconstruction. | Miguel A Hernandez Bartolome Sagrario Fuerte Ruiz Israel Manzanedo Romero Beatriz Ramos Lojo Ignacio Rodriguez Prieto Luis Gimenez Alvira Rosario Granados Carreo Manuel Limones Esteban | 2009 | World Journal of Gastroenterology2009，15，28： | 4 |
| 3 | Benchmarking of two three-dimensional numerical models in time/space domain to predict railway-induced ground vibrations显示文摘In the last 30 years,the scientific community has developed and proposed different models and numerical approaches for the study of vibrations induced by railway traffic.Most of them are formulated in the frequency/wave number domain and with a 2.5D approach.Three-dimensional numerical models formulated in the time/space domain are less frequently used,mainly due to their high computational cost.Notwithstanding,these models present very attractive characteristics,such as the possibility of considering nonlinear behaviors or the modelling of excess pore pressure and non-homogeneous and non-periodic geometries in the longitudinal direction of the track.In this study,two 3D numerical approaches formulated in the time/space domain are compared and experimentally validated.The first one consists of a finite element approach and the second one of a finite difference approach.The experimental validation in an actual case situated in Carregado(Portugal)shows an acceptable fitting between the numerical results and the actual measurements for both models.However,there are some differences among them.This study therefore includes some recommendations for their use in practical soil dynamics and geotechnical engineering. | Jesus Fernandez-Ruiz Luis E.Medina Rodriguez Pedro Alves Costa Margarita Martinez-Diaz | 2021 | Earthquake Engineering and Engineering Vibration2021，20，1： | 2 |
| 4 | Infrared fluorescence imaging of infarcted hearts with A@S nanodots显示文摘Ag2S nano dots have already bee n dem onstrated as promisi ng n ear-i nfrared (NIR-II, 1.0-1.45 pm) emitting nan oprobes with low toxicity, high penetration and high resolution for in vivo imaging of, for example, tumors and vasculature. In this work, we have systematically investigated the pote ntial applicati on of function alized Ag2S nano dots for accurate imaging of damaged myocardium tissues after a myocardial in farction in duced by either partial or global ischemia. Ag2S nano dots surface-function alized with the an giote nsin II peptide (ATI I) have show n over 10-fold enhanced binding efficiency to damaged tissues than non-specifically (PEG) functionalized Ag2S nanodots due to their interaction with the upregulated angiotensin II receptor type I (AT1R). It is demonstrated how the NIR-II images generated by ATII-functionalized Ag2S nanodots contain valuable information about the location and extension of damaged tissue in the myocardium allowing for a proper identification of the occluded artery as well as an in direct evaluati on of the damage level. The pote ntial applicati on of Ag2S nano dots in the n ear future for in vivo imaging of myocardial infarction was also corroborated by performing proof of concept whole body imaging experiments. | Dirk H. Ortgies Angel Luis Garcia-Villalon Miriam Granado Sara Amor Emma Martin Rodriguez Harrisson DA Santos Jingke Yao Jorge Rubio-Retama Daniel Jaque | 2019 | Nano Research2019，12，4： | 2 |
| 5 | Development and test verification of air temperature model for Chinese solar and Spainish Almeria-type greenhouses显示文摘Growth can be defined as an increment in biomass or an increment in weight or height of the organs of the plant influenced by physiological processes.Many of these processes have their limits genetically determined,but climate and irrigation play an important role.Because of its importance,microclimate has been extensively studied in the modeling as a surrounding condition which is imposed by the exterior climate.The main objective of this work was to develop a temperature model based on the energy balance dynamics at two different greenhouse locations-South-eastern Spain and Northern China,and the traditional structures of Chinese solar greenhouse and Almería-type multi-span greenhouse were taken into account.The final model was developed by combining the external conditions,the actuator influence and the crop growth,where the temperature is influenced by soil,crop,cover,actuators,back wall and greenhouse geometry.The model took into account the energy lost by convective and conductive fluxes,as well as the energy supplied by solar radiation and heating systems.The soil and the back wall are the main media for energy storage.The temperature dynamic was determined by a physical model,which considered the energy balance from a holistic point of view-as a sub-model for a customizable interface among the external climate,the plant and the greenhouse system.The influences of different subsystems included in the temperature model were analyzed and evaluated.The results showed a high R^(2)value of 0.94 for Beijing and 0.95 for Almeria,and the average error was low,of which the MAE and RMSE were 0.71 and 1.365 for Almeria and 0.62 and 1.102 for Beijing,respectively.Thus,the model can be considered as a powerful tool for control design purposes in microclimate systems. | Jorge Antonio Sanchez-Molina Li Ming Francisco Rodriguez Jose Luis Guzman Wang Hui Yang Xinting | 2017 | International Journal of Agricultural and Biological Engineering2017，10，4： | 2 |
| 6 | Estimation of visceral fat is useful for the diagnosis of significant fibrosis in patients with non-alcoholic fatty liver disease显示文摘BACKGROUND Obesity is a risk factor for non-alcoholic fatty liver disease(NAFLD),although obese patients with NAFLD do not always develop significant fibrosis.The distribution of body fat could predict the risk of NAFLD progression.AIM To investigate the role of bioelectrical impedance-estimated visceral fat(VF)in assessing NAFLD severity.METHODS In this cross-sectional study,patients with biopsy-proven NAFLD were prospectively included.All patients underwent anthropometric evaluation,blood tests and bioelectrical impedance analysis.RESULTS Between 2017 and 2020,119 patients were included[66.4%male,56 years(SD 10.7),62.2%obese,61.3%with metabolic syndrome].Sixty of them(50.4%)showed significant fibrosis(≥F2)in liver biopsy.Age,VF and metabolic syndrome were associated with significant fibrosis(61 years vs 52 years,16.4 vs 13.1,73.3%vs 49.2%,respectively;P<0.001 for all).In the multivariate analysis,VF and age were independently associated with significant fibrosis(VF,OR:1.11,95%CI:1.02-1.22,P=0.02;age,OR:1.08,95%CI:1.03-1.12,P<0.01).A model including these variables showed and area under the receiver operating characteristic curve(AUROC)of 0.75,which was not inferior to transient elastography or NAFLD fibrosis score AUROCs.We developed a nomogram including age and VF for assessing significant fibrosis in routine practice.CONCLUSION VF is a surrogate marker of liver fibrosis in patients with NAFLD.Bioelectrical impedance analysis is an inexpensive and simple method that can be combined with age to guide patient referral when other resources may be unavailable. | Marta Hernández-Conde Elba Llop Carlos Fernández Carrillo Beatriz Tormo Javier Abad Luis Rodriguez Christie Perelló Marta López Gomez JoséLuis Martínez-Porras Natalia Fernández Puga Maria Trapero-Marugan Enrique Fraga Carlos Ferre Aracil JoséLuis Calleja Panero | 2020 | World Journal of Gastroenterology2020，26，42： | 2 |
| 7 | Acute Pancreatitis During Pregnancy显示文摘 | Shou–Jiang Tang Edmundo Rodriguez–Frias Sundeep Singh Marlyn J. Mayo Saad F. Jazrawi Jayaprakash Sreenarasimhaiah Luis F. Lara Don C. Rockey | 2010 | Clinical Gastroenterology and Hepatology2010，，1： | 2 |
| 8 | Fluorescent competitive flow - through assay for chloramphenicol using molecularly imprinted polymers 显示文摘 | Jorge Luis SuOrez - Rodriguez Marta Elena Diaz - Garcia | 2001 | Biosensors & Bioeleetronics2001，16，912： | 1 |
| 9 | Aluminum tolerance in transgenic plants by alteration of citrate synthesis 显示文摘 | Juan Manuel de la Fuente Verenice Ramirez- Rodriguez Jose Luis Cabrera-Ponce | | Science0，276，6： | 1 |
| 10 | OPTICOM:Advanced automatic monitoring system of local combustion conditions for improving boiler performance in PC power plants显示文摘 | Francisco Rodriguez Enrique Toca Vicente Cortes Luis Canadas | 2002 | Fuel2002，81，： | 1 |
| 11 | The natural history of compensated HCV-related cirrhosis: A prospective long-term study显示文摘 | Eduardo Vilar Gomez Yoan Sanchez Rodriguez Luis Calzadilla Bertot Ana Torres Gonzalez Yadina Martinez Perez Enrique Arus Soler Ali Yasells Garcia Luis Perez Blanco | 2012 | Journal of Hepatology2012，，： | 1 |
| 12 | Performance of cold-preserved rat liver Microorgans as the biological component of a simplified prototype model of bioartificial liver显示文摘AIM To develop a simplified bioartificial liver(BAL) device prototype, suitable to use freshly and preserved liver Microorgans(LMOs) as biological component. METHODS The system consists of 140 capillary fibers through which goat blood is pumped. The evolution of hema-tocrit, plasma and extra-fiber fluid osmolality was evaluated without any biological component, to characterize the prototype. LMOs were cut and cold stored 48 h in BG35 and Via Span~? solutions. Fresh LMOs were used as controls. After preservation, LMOs were loaded into the BAL and an ammonia overload was added. To assess LMOs viability and functionality, samples were taken to determine lactate dehydrogenase(LDH) release and ammonia detoxification capacity. RESULTS The concentrations of ammonia and glucose, and the fluids osmolalities were matched after the first hour of perfusion, showing a proper exchange between blood and the biological compartment in the minibioreactor. After 120 min of perfusion, LMOs cold preserved in BG35 and Via Span~? were able to detoxify 52.9% ± 6.5% and 53.6% ± 6.0%, respectively, of the initial ammonia overload. No significant differences were found with Controls(49.3% ± 8.8%, P < 0.05). LDH release was 6.0% ± 2.3% for control LMOs, and 6.2% ± 1.7% and 14.3% ± 1.1% for BG35 and Via Span~? cold preserved LMOs, respectively(n = 6, P < 0.05). CONCLUSION This prototype relied on a simple design and excellent performance. It’s a practical tool to evaluate the detoxification ability of LMOs subjected to different preservation protocols. | María Dolores Pizarro María Gabriela Mediavilla Alejandra Beatriz Quintana ángel Luis Scandizzi Joaquín Valentín Rodriguez María Eugenia Mamprin | 2016 | World Journal of Hepatology2016，8，33： | 1 |
| 13 | Phylogeographic characteristics of vesicular stomatitis New Jersey viruses circulating in Mexico from 2005 to 2011 and their relationship to epidemics in the United States显示文摘 | Lauro Velazquez-Salinas Steven J. Pauszek Selene Zarate Francisco J. Basurto-Alcantara Antonio Verdugo-Rodriguez Andres M. Perez Luis L. Rodriguez | 2014 | Virology2014，，： | 1 |
| 14 | Acute Pancreatitis During Pregnancy显示文摘 | Shou–Jiang Tang Edmundo Rodriguez–Frias Sundeep Singh Marlyn J. Mayo Saad F. Jazrawi Jayaprakash Sreenarasimhaiah Luis F. Lara Don C. Rockey | 2010 | Clinical Gastroenterology and Hepatology2010，，1： | 1 |
| 15 | A conduction-convection design for liquid flow sensing显示文摘 | Luis Castaner Vicente Jimenez Manuel Dominguez Francesc Masana Angel Rodriguez | 1998 | Sensors and Actuators A1998，66，13： | 1 |
| 16 | Second-law efficiency analysis of a coal gasification process 显示文摘 | Luis Rodriguez S J Gaggioli R A | 1980 | The Canadian Journal of Chemical Engineering1980，58，3： | 1 |
| 17 | Calculation of available energy quanlities 显示文摘 | LUIS RODRIGUEZ S J | 1980 | ACS1980，，： | 1 |
| 18 | Imaging Crohn Disease: MR Enterography显示文摘 | Pablo Rodriguez Ramiro Mendez Fatima Matute Paula Hernandez Juan Luis Mendoza | 2014 | Journal of Computer Assisted Tomography2014，，： | 1 |
| 19 | Low-dose aspirin for the prevention of atherothrombosis显示文摘 | Patrono C Luis A Rodriguez G | 2005 | N Engl J Med2005，353，： | 1 |
| 20 | A Vector Control Technique for Medium Voltage Multilevel Inverters显示文摘 | Rodriguez Jo se Moran Luis Correa Pablo | 2002 | IEEE Trans on Industrial Electronics2002，49，4： | 1 |
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