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| 1 | Regional Disparity and Convergence of China's Inbound Tourism Economy显示文摘Comprehending regional characteristics and influencing factors of China's inbound tourism economy is im-portant to make effective policies that will help inbound tourism develop harmoniously and shrink regional disparity.This paper studied the regional disparity and convergence of China's inbound tourism economy during 1996-2008 with the methods of σ-convergence,club convergence and β-convergence.The results indicate that 1) inbound tourism receipts per capita(ITRPC) of the whole country,the eastern,central and western regions presented the rapid increas-ing trend;2) ITRPC of the whole country was characterized by convergence;3) the eastern region presented club con-vergence,but the central and western regions did not show this trend;4) the star-hotel levels and investment in fixed assets for the tourism industry per capita had a same trend to growth rates of ITRPC,promoting inbound tourism de-velopment,and there was no difference among the 31 provinces(municipalities) in the mainland of China;5) but the proportion of employed persons in the tourism industry accounting for total population and the proportion of the terti-ary industry accounting for GDP had a reversal trend to growth rates of ITRPC,shrinking the provincial disparity in inbound tourism economy,and there were differences between the developed provinces and the developing provinces.Based on these analyses,we put forward some suggestions for the developing provinces to speed up inbound tourism economy. | WANG Shuxin HE Yuanqing WANG Xueding ZHU Guofeng CAO Weihong | 2011 | Chinese Geographical Science2011，21，6： | 40 |
| 2 | Hydroformylation of alkenes over rhodium supported on the metal-organic framework ZlF-8显示文摘 | Chao Hou Guofeng Zhao Yongjun Ji Zhiqiang Niu Dingsheng Wang Yadong Li | 2014 | Nano Research2014，7，9： | 18 |
| 3 | A Chromosome-Scale Genome Assembly of Paper Mulberry(Bmussonetia papyrifera)Provides New Insights into Its Forage and Papermaking Usage显示文摘Paper mulberry(Broussonetia papyrifera)is a well-known woody tree historically used for Cai Lun papermaking,one of the four great inventions of ancient China.More recently,Paper mulberry has also been used as forage to address the shortage of feedstuff because of its digestible crude fiber and high protein contents.In this study,we obtained a chromosome-scale genome assembly for Paper mulberry using integrated approaches,including Illumina and PacBio sequencing platform as well as Hi-C,optical,and genetic maps.The assembled Paper mulberry genome consists of 386.83 Mb,which is close to the estimated size,and 99.25%(383.93 Mb)of the assembly was assigned to 13 pseudochromosomes.Comparative genomic analysis revealed the expansion and contraction in the flavonoid and lignin biosynthetic gene families,respectively,accounting for the enhanced flavonoid and decreased lignin biosynthesis in Paper mulberry.Moreover,the increased ratio of syringyl-lignin to guaiacyl-lignin in Paper mulberry underscores its suitability for use in medicine,forage,papermaking,and barkcloth making.We also identified the rootassociated microbiota of Paper mulberry and found that Pseudomonas and Rhizobia were enriched in its roots and may provide the source of nitrogen for its stems and leaves via symbiotic nitrogen fixation.Collectively,these results suggest that Paper mulberry might have undergone adaptive evolution and recruited nitrogen-fixing microbes to promote growth by enhancing flavonoid production and altering lignin monomer composition.Our study provides significant insights into genetic basis of the usefulness of Paper mulberry in papermaking and barkcloth making,and as forage.These insights will facilitate further domestication and selection as well as industrial utilization of Paper mulberry worldwide. | Xianjun Peng Hui Liu Peilin Chen Feng Tang Yanmin Hu Fenfen Wang Zhi Pi Meiling Zhao Naizhi Chen Hui Chen Xiaokang Zhang Xueqing Yan Min Liu Xiaojun Fu Guofeng Zhao Pu Yao Lili Wang He Dai Xuming Li Wei Xiong Wencai Xu Hongkun Zheng Haiyan Yu Shihua Shen | 2019 | Molecular Plant2019，12，5： | 18 |
| 4 | Spatial distribution and temporal trends in potential evapotranspiration over Hengduan Mountains region from 1960 to 2009显示文摘在 19612009 期间在 Hengduan 山区域基于 20 个车站的气象学的数据,潜在的土壤水分蒸发蒸腾损失总量的年度、季节的变化与 Penman-Monteith 模型一起在联合被分析。与在 ArcGIS 下面的花键插值的方法,潜在的土壤水分蒸发蒸腾损失总量的空间分发被介绍研究地区性的差别,并且关联分析被用来讨论影响潜在的土壤水分蒸发蒸腾损失总量的主导的因素。结果显示自从 1960 年代,年度潜在的土壤水分蒸发蒸腾损失总量显示出一个减少的趋势,特别从 1980 年代到 1990 年代,当自从 2000,它显示出一个增加的趋势时。地区性的潜在的土壤水分蒸发蒸腾损失总量显示出 0.17 公里 a1 的率。在 Hengduan 山的北方,中间和南方的潜在的土壤水分蒸发蒸腾损失总量在学习时期上展出了减少的趋势,并且它的地区性的趋势在从西南的衰落上到东北。 | ZHU Guofeng HE Yuanqing PU Tao WANG Xufeng JIA Wenxiong LI Zongxing XIN Huijuan | 2012 | Journal of Geographical Sciences2012，22，1： | 16 |
| 5 | Direct numerical simulation of particle-fluid systems by combining time-driven hard-sphere model and lattice Boltzmann method显示文摘A coupled numerical method for the direct numerical simulation of particle-fluid systems is formulated and implemented,resolving an order of magnitude smaller than particle size.The particle motion is described by the time-driven hard-sphere model,while the hydrodynamic equations governing fluid flow are solved by the lattice Boltzmann method(LBM).Particle-fluid coupling is realized by an immersed boundary method(IBM),which considers the effect of boundary on surrounding fluid as a restoring force added to the governing equations of the fluid.The proposed scheme is validated in the classical flow-around-cylinder simulations,and preliminary application of this scheme to fluidization is reported,demonstrating it to be a promising computational strategy for better understanding complex behavior in particle-fluid systems. | Limin Wang Guofeng Zhou Xiaowei Wang Qingang xiong Wei Ge | 2010 | Particuology2010，8，4： | 12 |
| 6 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 7 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 8 | Microstructure and mechanical properties of ultra-fine grained MoNbTaTiV refractory high-entropy alloy fabricated by spark plasma sintering显示文摘The MoNbTaTiV refractory high-entropy alloy(RHEA)with ultra-fine grains and homogeneous microstructure was successfully fabricated by mechanical alloying(MA)and spark plasma sintering(SPS).The microstructural evolutions,mechanical properties and strengthening mechanisms of the alloys were systematically investigated.The nanocrystalline mechanically alloyed powders with simple bodycentered cubic(BCC)phase were obtained after 40 h MA process.Afterward,the powders were sintered using SPS in the temperature range from 1500℃to 1700℃.The bulk alloys were consisted of submicron scale BCC matrix and face-centered cubic(FCC)precipitation phases.The bulk alloy sintered at 1600℃had an average grain size of 0.58μm and an FCC precipitation phase of 0.18μm,exhibiting outstanding micro-hardness of 542 HV,compressive yield strength of 2208 MPa,fracture strength of 3238 MPa and acceptable plastic strain of 24.9%at room temperature.The enhanced mechanical properties of the MoNbTaTiV RHEA fabricated by MA and SPS were mainly attributed to the grain boundary strengthening and the interstitial solid solution strengthening.It is expectable that the MA and SPS processes are the promising methods to synthesize ultra-fine grains and homogenous microstructural RHEA with excellent mechanical properties. | Qing Liu Guofeng Wang Xiaochong Sui Yongkang Liu Xiao Li Jianlei Yang | 2019 | Journal of Materials Science & Technology2019，35，11： | 11 |
| 9 | Piezotronic effect enhanced Schottky-contact ZnO micro/nanowire humidity sensors显示文摘 | Guofeng Hu Ranran Zhou Ruomeng Yu Lin Dong Caofeng Pan Zhong Lin Wang | 2014 | Nano Research2014，7，7： | 11 |
| 10 | Porous bimetallic Pt-Fe nanocatalysts for highly efficient hydrogenation of acetone显示文摘多孔的 Pt-Fe 二金属的 nanocrystals 被综合了经由自己组装并且能有效地从丙酮便于 2-propanol 的合成。二金属的催化剂为一个连续过程有三维的隧道和多达 972 h 1 的表演周转频率(TOF ) 超过 50 h。初步的机械学的研究建议高反应与由二金属的 Pt-Fe 合金和 Fe 2 O 3x 。一基于模型系统理解真实催化行为和催化机制被显示了帮助制作改进 Pt/Fe 3 有为大规模工业应用有大潜力的增加的活动和一生的 O 4 催化剂。 | Yongjun Ji Yuen Wu Guofeng Zhao Dingsheng Wang Lei Liu Wei He Yadong Li | 2015 | Nano Research2015，8，8： | 10 |
| 11 | Human bronchial epithelial cell injuries induced by fine particulate matter from sandstorm and non-sandstorm periods:Association with particle constituents显示文摘Epidemiological studies have demonstrated the exacerbation of respiratory diseases following sandstorm-derived particulate matter(PM) exposure.The presence of anthropogenic and biological agents on the sandstorm PM and the escalation of PM < 2.5 μm(PM2.5)pollution in China have led to serious concerns regarding the health effects of PM2.5during Asian sandstorms.We investigated how changes in PM2.5composition,as the weather transitioned towards a sandstorm,affected human airway epithelial cells.Six PM2.5samples covering two sandstorm events and their respective background and transition periods were collected in Baotou,an industrial city near the Gobi Desert in China.PM samples from all three periods had mild cytotoxicity in human bronchial epithelial cell line BEAS-2B,which was positively correlated with the contents of polycyclic aromatic hydrocarbons and several metals.All PM samples potently increased the release of interleukin-6(IL-6) and interleukin-8(IL-8).Endotoxin in all samples contributed significantly to the IL-6 response,with only a minor effect on IL-8.Cr was positively correlated with both IL-6 and IL-8 release,while Si was only associated with the increase of IL-6.Our study suggests that local agricultural and industrial surroundings in addition to the sandstorm play important roles in the respiratory effects of sandstorm-derived PM. | Bin Wang Ning Li Furong Deng Nicholas Buglak George Park Shu Su Aiguo Ren Guofeng Shen Shu Tao Xinbiao Guo | 2016 | Journal of Environmental Sciences2016，28，9： | 9 |
| 12 | In-situ fabricated anisotropic halide perovskite nanocrystals in polyvinylalcohol nanofibers: Shape tuning and polarized emission显示文摘We report an in-situ fabrication of halide perovskite (CH3NH3PbX3,CH3NH3 =methylammonium,MA,X =Cl,Br,I) nanocrystals in polyvinylalcohol (PVA) nanofibers (MAPbX3@PVA nanofibers) through electrospinning a perovskite precursor solution.With the content of the precursors increased,the resulting MAPbBr3 nanocrystals in PVA matrix changed the shape from ellipsoidal to pearl-like,and finely into rods-like.Optimized MAPbBr3@PVA nanofibers show strong polarized emission with the photoluminescence quantum yield of up to 72%.We reveal correlations between the shape of in-situ fabricated perovskite nanocrystals and the polarization degree of their emission by comparing experimental data from the single nanofiber measurements with theoretical calculations.Polarized emission of MAPbBr3@PVA nanofibers can be attributed to the dielectric confinement and quantum confinement effects.Moreover,nanofibers can be efficiently aligned by using parallel positioned conductor strips with an air gap as collector.A polarization ratio of 0.42 was achieved for the films of well-aligned MAPbBr3@PVA nanofibers with a macroscale size of 0.5 cm × 2 cm,which allows potential applications in displays,lasers,waveguides,etc. | Linghai Meng Changgang Yang Jingjia Meng Yongzhi Wang Yong Ge Ziqiang Shao Guofeng Zhang Andrey L.Rogach Haizheng Zhong | 2019 | Nano Research2019，12，6： | 9 |
| 13 | Anti-breast cancer effects and mechanisms of Xihuang pill on human breast cancer cell lines显示文摘OBJECTIVE: To investigate the anti-breast cancer(BC) effects and mechanisms of action of Xihuang pill(XHP) by conducting in vitro experiments on human BC cell lines. METHODS: Two human BC cell lines(MCF-7 and MDAMB231) were cultured and treated with XHP. Cell viability was detected using the 3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide(MTT) assay. Flow cytometry was used to measure the cell cycle and apoptosis. The cell cycle was analyzed with propidium iodide staining. Apoptosis was evaluated using the Annexin V-fluorescein isothiocyanate/propidium iodide method. Western blotting was used to analyze the expression of estrogen receptor(ER)-α and ER-β.RESULTS: XHP had growth-inhibitory effects on MCF-7 and MDA-MB231 cells with a half-maximal inhibitory concentration(IC50) of 10.14 mg/mL(MCF-7) and 8.98 mg/mL(MDA-MB231). Apoptosis was induced to some extent. Certain changes in the ER were caused. Upregulation of ER-α protein was found in MCF-7 cells. ER-β expression in MDA-MB231 cells was increased. Cell-cycle arrest was not observed in the two BC cell lines. ER-β expression in MCF-7 cells was unchanged. No ER-α expression was shown in MDA-MB231 cells. CONCLUSION: These data suggest that XHP can affect cell viability and cause apoptosis, but that the cell cycle is not blocked. XHP has a certain impact on ER expression, but its mechanisms of action of anti-BC effects may not be due to regulation of ER expression. | Guofeng Pan Wandan Wang Lan Wang Fangbo Zhang Xiaojie Yin Jianlu Wang Rixin Liang | 2013 | Journal of Traditional Chinese Medicine2013，33，6： | 8 |
| 14 | Efficient degradation of chlorobenzene in a non-thermal plasma catalytic reactor supported on CeO_2/HZSM-5 catalysts显示文摘Chlorobenzene removal was investigated in a non-thermal plasma reactor using CeO_2/HZSM-5catalysts.The performance of catalysts was evaluated in terms of removal and energy efficiency.The decomposition products of chlorobenzene were analyzed.The results show that CeO_2/HZSM-5 exhibited a good catalytic activity,which resulted in enhancements of chlorobenzene removal,energy efficiency,and the formation of lower amounts of by-products.With regards to CO_2 selectivity,the presence of catalysts favors the oxidation of by-products,leading to a higher CO_2 selectivity.With respect to ozone,which is considered as an unavoidable by-product in air plasma reactors,a noticeable decrease in its concentration was observed in the presence of catalysts.Furthermore,the stability of the catalyst was investigated by analyzing the evolution of conversion in time.The experiment results indicated that CeO_2/HZSM-5 catalysts have excellent stability:chlorobenzene conversion only decreased from 78%to 60%after 75 hr,which means that the CeO_2/HZSM-5 suffered a slight deactivation.Some organic compounds and chlorinated intermediates were adsorbed or deposited on the catalysts surface as shown by the results of Fourier Transform Infrared(FT-IR) spectroscopy,scanning electron microscope(SEM) and energy dispersive X-ray spectroscopy(EDS) analyses of the catalyst before and after the reaction,revealing the cause of catalyst deactivation. | Liying Jiang Guofeng Nie Runye Zhu Jiade Wang Jianmeng Chen Yubo Mao Zhuowei Cheng Willam A.Anderson | 2017 | Journal of Environmental Sciences2017，29，5： | 8 |
| 15 | Multiscale hierarchical analysis of rock mass and prediction of its mechanical and hydraulic properties显示文摘Engineering geological and hydro-geological characteristics of foundation rock and surrounding rock mass are the main factors that affect the stability of underground engineering. This paper presents the concept of multiscale hierarchical digital rock mass models to describe the rock mass, including its structures in different scales and corresponding scale dependence. Four scales including regional scale,engineering scale, laboratory scale and microscale are determined, and the corresponding scaledependent geological structures and their characterization methods are provided. Image analysis and processing method, geostatistics and Monte Carlo simulation technique are used to establish the multiscale hierarchical digital rock mass models, in which the main micro-and macro-structures of rock mass in different geological units and scales are reflected and connected. A computer code is developed for numerically analyzing the strength, fracture behavior and hydraulic conductivity of rock mass using the multiscale hierarchical digital models. Using the models and methods provided in this paper, the geological information of rock mass in different geological units and scales can be considered sufficiently,and the influence of downscale characteristics(such as meso-scale) on the upscale characteristics(such as engineering scale) can be calculated by considering the discrete geological structures in the downscale model as equivalent continuous media in the upscale model. Thus the mechanical and hydraulic properties of rock mass may be evaluated rationally and precisely. The multiscale hierarchical digital rock mass models and the corresponding methods proposed in this paper provide a unified and simple solution for determining the mechanical and hydraulic properties of rock mass in different scales. | Xiaoli Liu Guofeng Han Enzhi Wang Sijing Wang Kumar Nawnit | 2018 | Journal of Rock Mechanics and Geotechnical Engineering2018，10，4： | 8 |
| 16 | Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 expression in early focal cerebral infarction following urokinase thrombolysis in rats显示文摘Activity of matrix metalloproteinase-9 increases following cerebral ischemia/reperfusion,and is associated with cerebral microvascular permeability,blood-brain barrier destruction,inflammatory cell infiltration and brain edema.Matrix metalloproteinase-9 also likely participates in thrombolysis.A rat model of middle cerebral artery infarction was established by injecting autologous blood clots into the internal carotid artery.At 3 hours following model induction,urokinase was injected into the caudal vein.Decreased neurological severity score,reduced infarct volume,and increased expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 were observed in the cerebral cortex 24 hours after urokinase thrombolysis.These results suggest that urokinase can suppress damage in the acute-early stage of cerebral infarction. | Yuqiang Song Hongli Zou Guofeng Wang Hongxia Yang Zhaohong Xie Jianzhong Bi | 2012 | Neural Regeneration Research2012，7，17： | 6 |
| 17 | Pt/Y2O3:Eu3+ composite nanotubes: Enhanced photoluminescence and application in dye-sensitized solar cells显示文摘Y (哦)3:Eu3+ nanotubes 用一个灵巧的热水的方法被综合,然后,磅粒子在使用真空抽取的联合并且退火的 nanotubes 的表面上被种。产生 Pt/Y 2 O 3:Eu3+合成 nanotubes 不仅在 255-nm 或 468-nm 刺激下面展出了提高的红光而且能也被用来改进敏化染料的太阳能电池的效率,导致8.33%的效率,没有合成 nanotubes ,它与一节太阳能电池相比代表11.96%的重要改进。电气化学的阻抗光谱学结果显示 TiO 2-dye|I 3-/I - 电解质的界面的抵抗 TiO 2-Pt/Y2 合成房间多是的 O 3:Eu3+ 比一个纯 TiO 2 房间的小。另外, TiO 2-Pt/Y2 O 3:Eu3+ 合成房间比纯 TiO 2 房间展出了一更短的电子运输时间和更长的电子再结合时间。 | Mingqi Yu Jiamin Su Guofeng Wang Yadong Li | 2016 | Nano Research2016，9，8： | 6 |
| 18 | Modulating the photoelectrons of g-C3N4 via coupling MgTi2O5 as appropriate platform for visible-light-driven photocatalytic solar energy conversion显示文摘Graphitic carbon nitride (g-C3N4) has become an attractive visible-light-responsive photocatalyst because of its semiconductor polymer compositions and easy-modulated band structure. However, the bulk g-C3N4 photocatalyst has the low separation efficiency of photogenerated carriers and unsatisfied surface catalytic performance, which leads to poor photocatalytic performance. As for this, MgTi2O5 with high chemical stability, wide band gap and negative conduction band was used as a suitable platform for coupling with g-C3N4 to enhance charge separation and promoted the photoactivity. Different from common approaches, here, we propose an innovative method to construct g-C3N4/MgTi2O5 nanocomposites featuring “0 + 1 >1' magnification effect to improve g-C3N4 photocatalytic performance under visible light irradiation. Additionally, compositing metal oxides of MgTi2O5 with g-C3N4 has proven to be a proper strategy to accelerate surface catalytic reactions in g-C3N4, and the photoinduced carriers were modulated to maintain thermodynamic equilibrium, which convincingly promotes the photocatalytic activity. The photocatalytic performance of the nanocomposites was measured by hydrogen production and CO2 reduction under visible light. The developed g-C3N4/MgTi2O5 nanocomposites with a 5 wt.% MgTi2O5 exhibits the highest H2 and CO yield under visible light and excellent stability compare to the other MgTi2O5 contents in composites. According to surface photo-voltage spectra, electrochemical CO2 reduction, photoluminescence, etc. The superior performance can be related to an enhanced electron lifetime, the promoted charge transfer and the increased electronic separation property of g-C3N4. Our work provides an approach to overcome the defect of pure g-C3N4, which accesses to composite with the second component matched well. | Jiaxin Shen Yanzhen Li Haoying Zhao Kai Pan Xue Li Yang Qu Guofeng Wang Dingsheng Wang | 2019 | Nano Research2019，12，8： | 6 |
| 19 | Grapevine VlbZIP30 improves drought resistance by directly activating VvNAC17 and promoting lignin biosynthesis through the regulation of three peroxidase genes显示文摘Drought stress severely affects grapevine quality and yield,and recent reports have revealed that lignin plays an important role in protection from drought stress.Since little is known about lignin-mediated drought resistance in grapevine,we investigated its significance.Herein,we show that VlbZIP30 mediates drought resistance by activating the expression of lignin biosynthetic genes and increasing lignin deposition.Transgenic grapevine plants overexpressing VlbZIP30 exhibited lignin deposition(mainly G and S monomers)in the stem secondary xylem under control conditions,which resulted from the upregulated expression of VvPRX4 and VvPRX72.Overexpression of VlbZIP30 improves drought tolerance,characterized by a reduction in the water loss rate,maintenance of an effective photosynthesis rate,and increased lignin content(mainly G monomer)in leaves under drought conditions.Electrophoretic mobility shift assay,luciferase reporter assays,and chromatin immunoprecipitation-qPCR assays indicated that VlbZIP30 directly binds to the G-box cis-element in the promoters of lignin biosynthetic(VvPRX N1)and drought-responsive(VvNAC17)genes to regulate their expression.In summary,we report a novel VlbZIP30-mediated mechanism linking lignification and drought tolerance in grapevine.The results of this study may be of value for the development of molecular breeding strategies to produce drought-resistant fruit crops. | Mingxing Tu Xianhang Wang Wuchen Yin Ya Wang Yajuan Li Guofeng Zhang Zhi Li Junyang Song Xiping Wang | 2020 | Horticulture Research2020，7，1： | 5 |
| 20 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
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