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| 1 | 大数据与开放数据的政策框架:问题、政策与建议显示文摘大数据与开放数据对电子公共服务、开放和透明政府以及政府公众与企业间的互动,都蕴藏着巨大的变革潜力。从'智慧'政府到变革政府,开放数据与大数据可推动协作,为农业、健康和交通运输等领域面临的挑战提出实时解决方案,推动更大程度的开放,并引领政策制定走向新时代。然而,开放数据与大数据也面临着一系列的政策挑战,如数据获取和发布、数字资产管理、归档和保存、隐私及安全等。本文以美国为背景,选择了有关开放数据与大数据的关键政策问题进行评论,并提出建议,以期推进数据驱动的创新。 | John Carlo Bertot 郑磊 徐慧娜 包琳达 | 2014 | 电子政务2014，，1： | 69 |
| 2 | Application of a biochemical and clinical model to predict individual survival in patients with end-stage liver disease显示文摘AIM:To investigate the capability of a biochemical and clinical model,BioCliM,in predicting the survival of cirrhotic patients.METHODS:We prospectively evaluated the survival of 172 cirrhotic patients.The model was constructed using clinical(ascites,encephalopathy and variceal bleeding) and biochemical(serum creatinine and serum total bilirubin) variables that were selected from a Cox proportional hazards model.It was applied to estimate 12-,52-and 104-wk survival.The model's calibration using the Hosmer-Lemeshow statistic was computed at 104 wk in a validation dataset.Finally,the model's validity was tested among an independent set of 85 patients who were stratified into 2 risk groups(low risk≤8 and high risk>8).RESULTS:In the validation cohort,all measures of fi t,discrimination and calibration were improved when the biochemical and clinical model was used.The proposed model had better predictive values(c-statistic:0.90,0.91,0.91) than the Model for End-stage Liver Disease(MELD) and Child-Pugh(CP) scores for 12-,52-and 104-wk mortality,respectively.In addition,the Hosmer-Lemeshow(H-L) statistic revealed that the biochemical and clinical model(H-L,4.69) is better calibrated than MELD(H-L,17.06) and CP(H-L,14.23).There were no significant differences between the observed and expected survival curves in the stratified risk groups(low risk,P=0.61;high risk,P=0.77).CONCLUSION:Our data suggest that the proposed model is able to accurately predict survival in cirrhotic patients. | Eduardo Vilar Gomez Luis Calzadilla Bertot Bienvenido Gra Oramas Enrique Arus Soler Raimundo Llanio Navarro Javier Diaz Elias Oscar Villa Jiménez Maria del Rosario Abreu Vazquez | 2009 | World Journal of Gastroenterology2009，15，22： | 6 |
| 3 | Antioxidant and immunomodulatory effects of Viusid in patients with chronic hepatitis C显示文摘AIM:To investigate the efficacy of Viusid,a nutritional supplement,as an antioxidant and an immunomodulator in patients with chronic hepatitis C.METHODS:Sixty patients with chronic hepatitis C who were non-responders to standard antiviral treatment were randomly assigned to receive Viusid(3 sachets daily,n=30) or placebo(n=30) for 24 wk.The primary outcome was the change in serum malondialdehyde and 4-hydroxyalkenals(lipid peroxidation products).Secondary outcomes were changes in serum tumor necrosis factor-α(TNF-α),interferon-γ(IFN-γ) and interleukin-10(IL-10).RESULTS:Statistically significant reductions in serum 4-hydroxyalkenals and malondialdehyde levels were observed in both groups in comparison with pretreatment values,but the patients who received Viusid showed a more marked reduction as compared with the control group(P=0.001).TNF-α levels significantly increased from 6.9 to 16.2 pg/mL(P< 0.01) in the patients who received placebo in comparison with almost unchanged levels,from 6.6 to 7.1 pg/mL(P=0.26),in the patients treated with Viusid(P=0.001).In addition,IL-10 levels were markedly increased in the patients treated with Viusid(from 2.6 to 8.3 pg/mL,P=0.04) in contrast to the patients assigned to placebo(from 2.8 to 4.1 pg/mL,P=0.09)(P=0.01).Likewise,the administration of Viusid markedly increased mean IFN-γ levels from 1.92 to 2.89 pg/mL(P< 0.001) in comparison with a reduction in mean levels from 1.80 to 1.68 pg/mL(P=0.70) in the placebo group(P< 0.0001).Viusid administration was well tolerated.CONCLUSION:Our results indicate that treatment with Viusid leads to a notable improvement of oxidative stress and immunological parameters in patients with chronic hepatitis C. | Eduardo Vilar Gomez Yadina Martinez Perez Hector Vega Sanchez Gretel Riveron Forment Enrique Arus Soler Luis Calzadilla Bertot Ali Yasells Garcia Maria del Rosario Abreu Vazquez Licet Gonzalez Fabian | 2010 | World Journal of Gastroenterology2010，16，21： | 2 |
| 4 | Component rotation and anterior knee pain after total knee arthroplasty显示文摘 | Schrader T Bertot AJ | 2001 | Clin Orthop2001，392，： | 1 |
| 5 | Using ICTs to create a culture of transparency: E-government and social media as openness and anti- corruption tools for societies 显示文摘 | Bertot J C Jaeger P T Grimes J M | 2010 | Government Information Quarterly2010，27，3： | 1 |
| 6 | Open government, open data and digital government 显示文摘 | Luis Felipe Luna-Reyes John C Bertot Sehl Mellouli | 2014 | Government Information Quarterly2014，31，1： | 1 |
| 7 | Developing national network statistics and performance measures for US Public Libraries: is- sues, findings and recommendations 显示文摘 | Bertot J C | 2000 | Performance Measurement and Metrics2000，，1： | 1 |
| 8 | Type-theoretic Functional Semantics显示文摘 | Capretta V Barman K | 2002 | Lncs2002，2410，： | 1 |
| 9 | Implications of harmonizing the future of the federal depository library program within e- government principles and policies 显示文摘 | John A Shuler Paul T Jaeger John Carlo Bertot | 2010 | Government Information Quarterly2010，27，1： | 1 |
| 10 | Universal service in a global networked environment:Selected issues and possible approaches 显示文摘 | Bertot J C McClure C R Owens K A | 1999 | Government In- formation Quarterly1999，16，4： | 1 |
| 11 | Using ICTs to create a culture of transparency: E-government and social media as openness and anti-corruption tools for societies 显示文摘 | Bertot J C Jaeger P T Grimes J M | 2010 | Government Information Quarterly2010，27，3： | 1 |
| 12 | Component rotation andanterior knee pain after total knee arthroplasty显示文摘 | Barrack R L Schrader T Bertot AJ | 2001 | Clin Orthop RelatRes2001，392，： | 1 |
| 13 | The natural history of compensated HCV-related cirrhosis: A prospective long-term study显示文摘 | Eduardo Vilar Gomez Yoan Sanchez Rodriguez Luis Calzadilla Bertot Ana Torres Gonzalez Yadina Martinez Perez Enrique Arus Soler Ali Yasells Garcia Luis Perez Blanco | 2012 | Journal of Hepatology2012，，： | 1 |
| 14 | Delivering e-government services and transforming communitiesthrough innovative partnerships: Public libraries, government agencies, andcommunity organizations显示文摘 | Luis F. Luna-Reyes Sehl Mellouli John C. Bertot John Carlo Bertot Paul T. Jaeger Ursula Gorham Natalie Greene Taylor Ruth Lincoln | 2013 | Information Polity2013，，2： | 1 |
| 15 | Component rotation and anterior knee pain after total knee arthroplasty 显示文摘 | Barrack RL Schrader T Bertot A J | 2001 | Clin Orthop2001，392，： | 1 |
| 16 | The value ofpreoperative aspiration before total knee revision 显示文摘 | Barrack RL Jennings RW Wolfe MW Bertot AJ | 1997 | Clin Or-thop1997，345，： | 1 |
| 17 | Intranasal vaccination with recombinant P6 protein and adamantylamide dipeptide as mucosal adjuvant confers efficient protection against otitis media and lung infection by nontypeable Haemophilus influenzae 显示文摘 | Bertot GM Becker PD Guzman CA | 2004 | J Infect Dis2004，189，7： | 1 |
| 18 | Using ]CTs to create a cul- ture of transparency:E-government and social media as open- ness and anti-corruption tools for societies 显示文摘 | Bertot J C Jaeger P T Grimes J M | 2010 | Government Information Quarterly2010，27，3： | 1 |
| 19 | The Federal Depository Library Program (FDLP), Academic Libraries, and Access to Government Information显示文摘 | Paul T. Jaeger John Carlo Bertot John A. Shuler | 2010 | The Journal of Academic Librarianship2010，，6： | 1 |
| 20 | The intersection of public policy and public access : digital divides, digital literacy, digital inclusion, and public libraries显示文摘 | Jaeger T Bertot J C Thompson K M | 2012 | Public Library Quarterly2012，31，6： | 1 |
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