|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Tooth regeneration: a revolution in stomatology and evolution in regenerative medicine显示文摘A tooth is a complex biological organ and consists of multiple tissues including the enamel, dentin, cementum and pulp. Tooth loss is the most common organ failure. Can a tooth be regenerated? Can adult stem cells be orchestrated to regenerate tooth structures such as the enamel, dentin, cementum and dental pulp, or even an entire tooth? If not, what are the therapeutically viable sources of stem cells for tooth regeneration? Do stem cells necessarily need to be taken out of the body, and manipulated ex vivo before they are transplanted for tooth regeneration? How can regenerated teeth be economically competitive with dental implants? Would it be possible to make regenerated teeth affordable by a large segment of the population worldwide? This review article explores existing and visionary approaches that address some of the above-mentioned questions. Tooth regeneration represents a revolution in stomatology as a shift in the paradigm from repair to regeneration: repair is by metal or artificial materials whereas regeneration is by biological restoration. Tooth regeneration is an extension of the concepts in the broad field of regenerative medicine to restore a tissue defect to its original form and function by biological substitutes. | Sibel Yildirim Susan Y. Fu Keith Kim Hong Zhou Chang Hun Lee Ang Li Sahng Gyoon Kim Shuang Wang Jeremy J. Mao | 2011 | International Journal of Oral Science2011，3，3： | 16 |
| 2 | 1999~2006年急性冠脉综合征患者死亡及心力衰竭发生率降低显示文摘背景:有关药物和介入治疗对ST段抬高型和非ST段抬高型急性冠脉综合征(non—ST-segment elevation acute coronary syndrome,NSTE ACS)患者的作用,随机试验已经提供了足够的证据,但是是否已经转化为相应的临床变化还不清楚。
目的:确定ST段抬高型心肌梗死(ST-segment elevation myocardial infarction,STEMI)和NSTE ACS患者的院内治疗改变是否伴随临床结果的改善。
设计、地点及患者:全球急性冠脉事件注册研究(Global Registry of Acute Coronary Events,GRACE)是一项多国家队列研究。自1999年7月1日至2006年12月31日,该研究共入选并随访了来自14个国家、113家医院的44372例ACS患者。
主要观测指标:当前循证药物和介入治疗应用的趋势及患者预后(死亡、充血性心力衰竭、肺水肿、心源性休克、卒中和心肌梗死)。
结果:随着研究时间的进展,相关药物的应用增加(β-受体阻滞剂、他汀类药物、血管紧张素转换酶抑制剂、行或未行经皮冠状动脉介入治疗[percutaneous coronary intervention,PCI]患者应用噻氯毗啶、糖蛋白Ⅱb/Ⅲa抑制剂和低分子肝素;P〈0.001)。STEMI患者药物再灌注治疗下降了22个百分点(95%可信区间[confidence interval,CI],-27~-17),而直接PCI增加了37个百分点(95%CI,33—41)。在NSTEMI患者中,PCI的比例显著升高了18个百分点(95%CI,15~20)。充血性心力衰竭和肺水肿在STEMI患者中降低了9个百分点(95%CI,-12~-6),在NSTEACS患者中降低了6.9个百分点(95%CI,-8.4~-4.7)。STEMI患者的院内死亡率降低了18个百分点(95%CI,-5.3~-1.9),心源性休克降低了24个百分点(95%CI,-4.3~-0.5)。校正了危险评分后,NSTEACS患者的院内死亡率降低了0.7个百分点(95%CI,-1.7~0.3);STEMI患者6个月随访时卒中发生率降低了0.8个百分点(95%CI,-1.7~0.1),心肌梗死发生率降低了2.8个百分点(95%CI,-6.4~0.9)。NSTEACS患者6个月死亡率降低了1.6个百分点(95%CI,-3.0~-0.1),卒中发生率降低了0.7个百分点(95%CI,-1.4~0.1)。
结论:在本项多国家观察性研究中,ACS患者治疗的改善与6个月新发心力衰竭、死亡率、卒中和心肌梗死发生率显著降低相关。 | Keith A. A. Fox Philippe Gabriel Steg Kim A. Eagle Shaun G. Goodman Frederick A. Anderson Christopher B. Granger Marcus D. Flather Andrzej Budaj Ann Quill Joel M. Gore 康俊萍(译) 马长生(校) | 2007 | 美国医学会杂志(中文版)2007，26，6： | 6 |
| 3 | Comparison of Yttrium-90 Radioembolization and Transcatheter Arterial Chemoembolization for the Treatment of Unresectable Hepatocellular Carcinoma显示文摘 | David A. Kooby Vasili Egnatashvili Swetha Srinivasan Abbas Chamsuddin Keith A. Delman John Kauh Charles A. Staley Hyun S. Kim | 2010 | Journal of Vascular and Interventional Radiology2010，，2： | 3 |
| 4 | Network Motif Detection: Algorithms, Parallel and Cloud Computing,and Related Tools显示文摘Network motif is defined as a frequent and unique subgraph pattern in a network, and the search involves counting all the possible instances or listing all patterns, testing isomorphism known as NP-hard and large amounts of repeated processes for statistical evaluation. Although many efficient algorithms have been introduced, exhaustive search methods are still infeasible and feasible approximation methods are yet implausible.Additionally, the fast and continual growth of biological networks makes the problem more challenging. As a consequence, parallel algorithms have been developed and distributed computing has been tested in the cloud computing environment as well. In this paper, we survey current algorithms for network motif detection and existing software tools. Then, we show that some methods have been utilized for parallel network motif search algorithms with static or dynamic load balancing techniques. With the advent of cloud computing services, network motif search has been implemented with MapReduce in Hadoop Distributed File System(HDFS), and with Storm, but without statistical testing. In this paper, we survey network motif search algorithms in general, including existing parallel methods as well as cloud computing based search, and show the promising potentials for the cloud computing based motif search methods. | Wooyoung Kim Martin Diko Keith Rawson | 2013 | Tsinghua Science and Technology2013，18，5： | 2 |
| 5 | Survival after gastric adenocarcinoma resection: Eighteen-year experience at a single institution显示文摘 | Steven C. Cunningham M.D. Farin Kamangar M.D. M.P.H. Min P. Kim M.D. Sommer Hammoud Raqeeb Haque Anirban Maitra M.B.B.S. Elizabeth Montgomery M.D. Richard E. Heitmiller M.D. F.A.C.S. Michael A. Choti M.D. F.A.C.S. Keith D. Lillemoe M.D. F.A.C.S. John | 2005 | Journal of Gastrointestinal Surgery2005，，5： | 2 |
| 6 | Activity of Crizotinib (PF02341066), a Dual Mesenchymal-Epithelial Transition (MET) and Anaplastic Lymphoma Kinase (ALK) Inhibitor, in a Non-small Cell Lung Cancer Patient with De Novo MET Amplification显示文摘 | Sai-Hong Ignatius Ou Eunice L. Kwak Christina Siwak-Tapp Joni Dy Kristin Bergethon Jeffrey W. Clark D. Ross Camidge Benjamin J. Solomon Robert G. Maki Yung-Jue Bang Dong-Wan Kim James Christensen Weiwei Tan Keith D. Wilner Ravi Salgia A. John Iafrate | 2011 | Journal of Thoracic Oncology2011，，5： | 2 |
| 7 | Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases显示文摘 | Sung-Jun Park Faiyaz Ahmad Andrew Philp Keith Baar Tishan Williams Haibin Luo Hengming Ke Holger Rehmann Ronald Taussig Alexandra L. Brown Myung K. Kim Michael A. Beaven Alex B. Burgin Vincent Manganiello Jay H. Chung | 2012 | Cell2012，，3： | 2 |
| 8 | Comparison of Central Corneal Thickness using Anterior Segment Optical Coherence Tomography vs Ultrasound Pachymetry显示文摘 | Hanna Y. Kim Donald L. Budenz Pak S. Lee William J. Feuer Keith Barton | 2008 | American Journal of Ophthalmology2008，，2： | 1 |
| 9 | Multimodal express package delivery: A service network design application显示文摘 | Kim Daeki Barnhart Cynthia Ware Keith Reinhardt Gregory | 1999 | Transportation Science1999，33，： | 1 |
| 10 | Efficacy of perioperative halo-gravity traction for treatment of severe scoliosis (≥100°)显示文摘 | Kei Watanabe Lawrence G. Lenke Keith H. Bridwell Yongjung J. Kim Marsha Hensley Linda Koester | 2010 | Journal of Orthopaedic Science2010，，6： | 1 |
| 11 | Network design for express shipment delivery 显示文摘 | Barnhart Cynthia Krishnan Niranjan Kim Daeki Ware Keith | 2002 | Computational Optimization and Applications2002，21，： | 1 |
| 12 | Adjacent Segment Disease FollowingLumbar/Thoracolumbar Fusion With Pedicle Screw Instrumentation: A Minimum 5-Year Follow-up显示文摘 | Gene Cheh Keith H. Bridwell Lawrence G. Lenke Jacob M. Buchowski Michael D. Daubs Yongjung Kim Christy Baldus | 2007 | Spine2007，，20： | 1 |
| 13 | Validation and Implementation of Targeted Capture and Sequencing for the Detection of Actionable Mutation, Copy Number Variation, and Gene Rearrangement in Clinical Cancer Specimens显示文摘 | Colin C. Pritchard Stephen J. Salipante Karen Koehler Christina Smith Sheena Scroggins Brent Wood David Wu Ming K. Lee Suzanne Dintzis Andrew Adey Yajuan Liu Keith D. Eaton Renato Martins Kari Stricker Kim A. Margolin Noah Hoffman Jane E. Churpek Jonathan | 2014 | The Journal of Molecular Diagnostics2014，，1： | 1 |
| 14 | 生物质对低浓度染料废物的协同多层吸收(英文)显示文摘Due to the high cost of adsorbents and their thermal regeneration in recent years,much research has focused on the search for cheaper adsorbents for treating wastewater from textile industry.The single component adsorption of an acidic dye,Acid Yellow 117,and a basic dye,Methylene Blue,onto several adsorbents—bamboo,waste wood,bamboo char,waste wood char,bamboo activated carbon,wood activated carbon and active carbon F400 were conducted.Based on a Langmuir analysis,the monolayer adsorption capacities were determined.Three of the adsorbents were selected for binary layer adsorption to check the multilayer concept and the potential application for better adsorbent usage.The two cheapest adsorbents,bamboo and wood are compared with the commercial activated carbon F400,and all three systems were successful. | Keith Kim Hung Choy Gordon Mckay | 2012 | Chinese Journal of Chemical Engineering2012，20，3： | 1 |
| 15 | Insertion and deletion in a non-essential region of the nonstructural protein 2 (nsp2) of porcine reproductive and respiratory syndrome (PRRS) virus: effects on virulence and immunogenicity显示文摘 | Dal-Young Kim Troy J. Kaiser Kyle Horlen Marcia L. Keith Lucas P. Taylor Rika Jolie Jay G. Calvert Raymond R. R. Rowland | 2009 | Virus Genes2009，，1： | 1 |
| 16 | Multimodal express package delivery: a service network design application 显示文摘 | KIM D CYNTHIA B KEITH W | 1999 | Transportation Sci1999，33，4： | 1 |
| 17 | Evidence for the epithelial to mesenchymal transition in biliary atresia fibrosis显示文摘 | Rosalyn Díaz Ji Won Kim Jia-Ji Hui Zhaodong Li Gary P. Swain Keith S.K. Fong Katalin Csiszar Pierre A. Russo Elizabeth B. Rand Emma E. Furth Rebecca G. Wells | 2008 | Human Pathology2008，，1： | 1 |
| 18 | 2014 Hypertension Recommendations From the Eighth Joint National Committee Panel Members Raise Concerns for Elderly Black and Female Populations显示文摘 | Lawrence R. Krakoff Robert L. Gillespie Keith C. Ferdinand Icilma V. Fergus Ola Akinboboye Kim A. Williams Mary Norine Walsh C. Noel Bairey Merz Carl J. Pepine | 2014 | Journal of the American College of Cardiology2014，，4： | 1 |
| 19 | Clinical outcomes of the Realize Adjustable Gastric Band-C at 2 years in a United States population显示文摘 | Scott A. Cunneen Collin E.M. Brathwaite Christopher Joyce Keith Gersin Keith Kim Jon L. Schram Erik B. Wilson Michael Schwiers Mario Gutierrez | 2013 | Surgery for Obesity and Related Diseases2013，，： | 1 |
| 20 | Does fibrin glue sealant decrease the rate of pancreatic fistula after pancreaticoduodenectomy? results of a prospective randomized trial显示文摘 | Keith D. Lillemoe John L. Cameron Min P. Kim Kurtis A. Campbell Patricia K. Sauter Joann A. Coleman Charles J. Yeo | 2004 | Journal of Gastrointestinal Surgery2004，，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员