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| 1 | Burden of Clostridium difficile infection between 2010 and 2013:Trends and outcomes from an academic center in Eastern Europe显示文摘AIM:To analyze the incidence and possible risk factors in hospitalized patients treated with Clostridium difficile infection(CDI).METHODS:A total of 11751 patients were admitted to our clinic between 1 January 2010 and 1 May2013.Two hundred and forty-seven inpatients were prospectively diagnosed with CDI.For the risk analysis a 1:3 matching was used.Data of 732 patients matched for age,sex,and inpatient care period and unit were compared to those of the CDI population.Inpatient records were collected from an electronic hospital database and comprehensively reviewed.RESULTS:Incidence of CDI was 21.0/1000 admissions(2.1%of all-cause hospitalizations and 4.45%of total inpatient days).The incidence of severe CDI was 12.6%(2.63/1000 of all-cause hospitalizations).Distribution of CDI cases was different according to the unit type,with highest incidence rates in hematology,gastroenterology and nephrology units(32.9,25 and24.6/1000 admissions,respectively) and lowest rates in 1.4%(33/2312) in endocrinology and general internal medicine(14.2 and 16.9/1000 admissions)units.Recurrence of CDI was 11.3%within 12 wk after discharge.Duration of hospital stay was longer in patients with CDI compared to controls(17.6 ± 10.8d vs 12.4 ± 7.71 d).CDI accounted for 6.3%of allinpatient deaths,and 30-d mortality rate was 21.9%(54/247 cases).Risk factors for CDI were antibiotic therapy[including third-generation cephalosporins or fluoroquinolones,odds ratio(OR) = 4.559;P < 0.001],use of proton pump inhibitors(OR = 2.082,P< 0.001),previous hospitaiization within 12 mo(OR = 3.167,P < 0.001),previous CDI(OR = 15.32;P < 0.001),while presence of diabetes mellitus was associated with a decreased risk for CDI(OR = 0.484;P< 0.001).Treatment of recurrent cases was significantly different from primary infections with more frequent use of vancomycin alone or in combination(P < 0.001),and antibiotic therapy duration was longer(P < 0.02).Severity,mortality and outcome of primary infections and relapsing cases did not significantly differ.CONCLUSION:CDI was accounted for significant burden with longer hospitaiization and adverse outcomes.Antibiotic,PPI therapy and previous hospitaiization or CDI were risk factors for CDI. | Zsuzsanna Kurti Barbara D Lovasz Michael D Mandel Zoltan Csima Petra A Golovics Bence D Csako Anna Mohas Lorant Gnczi Krisztina B Gecse Lajos S Kiss Miklos Szathmari Peter L Lakatos | 2015 | World Journal of Gastroenterology2015，21，21： | 6 |
| 2 | 1423 Pancreaticoduodenectomies for Pancreatic Cancer: A Single-Institution Experience显示文摘 | Jordan M. Winter John L. Cameron Kurtis A. Campbell Meghan A. Arnold David C. Chang JoAnn Coleman Mary B. Hodgin Patricia K. Sauter Ralph H. Hruban Taylor S. Riall Richard D. Schulick Michael A. Choti Keith D. Lillemoe Charles J. Yeo | 2006 | Journal of Gastrointestinal Surgery2006，，9： | 5 |
| 3 | Perspectives on the prevention and treatment of infection for orthopedic tissue engineering applications显示文摘The emergence of orthopedic tissue engineering devices as viable clinical solutions demands that the field address significant clinical complications associated with the implantation of foreign materials in the body,especially infection.While tissue engineering has focused on the development of methods to regenerate and repair,until recently there has been a relative dearth of literature regarding the intersection of tissue engineering and infection.In particular,local delivery of antimicrobials has long been of clinical interest,but only recently has that been translated into the realm of tissue engineering.In this perspective,we briefly review major modes of local delivery for infection prevention and treatment and discuss possible strategies for preventing implant-associated infections. | SHAH Sarita R KASPER F Kurtis MIKOS Antonios G | 2013 | Chinese Science Bulletin2013，58，35： | 4 |
| 4 | SYBR Green荧光定量粪检PCR法检测日本血吸虫感染的敏感性研究显示文摘目的建立快速、敏感、特异的检测日本血吸虫感染的SYBR Green荧光定量PCR法,准确评估其敏感性。方法将计数的日本血吸虫虫卵掺入健康水牛粪样中,制备人工阳性粪样。采用改良QIAamp DNA Stool Kit粪样DNA提取方法,提取人工阳性粪样DNA,进行SYBR Green荧光定量PCR,建立Ct值与粪样中克粪虫卵数(EPG)的关系;提取单独(不与牛阴性粪样混合)日本血吸虫虫卵DNA与虫卵生理盐水冲洗液DNA,行定量PCR检测,以对本方法进行严格质量控制。结果每200mg粪样仅含1个虫卵时,荧光定量PCR仍呈阳性,人工阳性粪样EPG的对数与PCR的Ct值存在线性关系。结论SYBR Green荧光定量粪检PCR法检测日本血吸虫虫卵DNA敏感性高,EPG对数与PCR的Ct值存在线性关系。 | 秦圆方 刘云 杜学利 孟睿 储凯 季旻珺 Jonathan D Kurtis 吴海玮 | 2009 | 中国病原生物学杂志2009，4，6： | 3 |
| 5 | Surgical Management of Bile Duct Injuries Sustained During Laparoscopic Cholecystectomy: Perioperative Results in 200 Patients显示文摘 | Jason K. Sicklick Melissa S. Camp Keith D. Lillemoe Genevieve B. Melton Charles J. Yeo Kurtis A. Campbell Mark A. Talamini Henry A. Pitt JoAnn Coleman Patricia A. Sauter John L. Cameron | 2005 | Annals of Surgery2005，，5： | 3 |
| 6 | Pancreatic Resection of Isolated Metastases from Nonpancreatic Primary Cancers显示文摘 | Sushanth Reddy MD Barish H. Edil MD John L. Cameron MD Timothy M. Pawlik MD MPH Joseph M. Herman MD Marta M. Gilson PhD Kurtis A. Campbell MD Richard D. Schulick MD Nita Ahuja MD Christopher L. Wolfgang MD PhD | 2008 | Annals of Surgical Oncology2008，，11： | 2 |
| 7 | 1423 pancreaticoduodenectomies for pancreatic cancer: A single-institution experience显示文摘 | Jordan M. Winter M.D. John L. Cameron M.D. Kurtis A. Campbell M.D. Meghan A. Arnold M.D. David C. Chang Ph.D. M.B.A. M.P.H. JoAnn Coleman C.R.N.P. Mary B. Hodgin C.M.S.R.N. Patricia K. Sauter C.R.N.P. Ralph H. Hruban M.D. Taylor S. Riall M.D. Richard D. | 2006 | Journal of Gastrointestinal Surgery2006，，9： | 2 |
| 8 | Effects of lithium nitrate admixture on early-age cement hydration显示文摘 | M.J. Millard K.E. Kurtis | 2007 | Cement and Concrete Research2007，，4： | 2 |
| 9 | Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinomad—part 3: Update on 5-year survival显示文摘 | Taylor S. Riall M.D. John L. Cameron M.D. Keith D. Lillemoe M.D. Kurtis A. Campbell M.D. Patricia K. Sauter C.R.N.P. JoAnn Coleman C.R.N.P. Ross A. Abrams M.D. Daniel Laheru M.D. Ralph H. Hruban M.D. Charles J. Yeo M.D | 2005 | Journal of Gastrointestinal Surgery2005，，9： | 2 |
| 10 | Prevalence and predictors of hospitalization in Crohn's disease in a prospective population-based inception cohort from 2000-2012显示文摘AIM: To analyze the prevalence, length and predictors of hospitalization in the biological era in the populationbased inception cohort from Veszprem province.METHODS: Data of 331 incident Crohn's disease(CD) patients diagnosed between January 1, 2000 and December 31, 2010 were analyzed(median age at diagnosis: 28; IQR: 21-40 years). Both in- and outpatient records were collected and comprehensively reviewed.RESULTS: Probabilities of first CD-related hospitalization and re-hospitalization were 32.3%, 45.5%,53.7% and 13.6%, 23.9%, 29.8%, respectively after one, three and five years of follow-up in Kaplan-Meier analysis. First-year hospitalizations were related to diagnostic procedures(37%), surgery or disease activity(27% and 21%). Non-inflammatory disease behavior at diagnosis(HR = 1.32, P = 0.001) and perianal disease(HR = 1.47, P = 0.04) were associated with time to first CD-related hospitalization, while disease behavior change(HR = 2.38, P = 0.002) and need for steroids(HR = 3.14, P = 0.003) were associated with time to first re-hospitalization in multivariate analyses.Early CD-related hospitalization(within the year of diagnosis) was independently associated with need for immunosuppressives(OR = 2.08, P = 0.001) and need for surgeries(OR = 7.25, P < 0.001) during the disease course.CONCLUSION: Hospitalization and re-hospitalization rates are still high in this cohort, especially during the first-year after the diagnosis. Non-inflammatory disease behavior at diagnosis was identified as the pivotal predictive factor of both hospitalization and rehospitalization. | Petra A Golovics Laszlo Lakatos Michael D Mandel Barbara D Lovasz Zsuzsanna Vegh Zsuzsanna Kurti Istvan Szita Lajos S Kiss Tunde Pandur Peter L Lakatos | 2015 | World Journal of Gastroenterology2015，21，23： | 2 |
| 11 | Mobile Pb isotopes in Proterozoic sedimentary basins as guides for exploration of uranium deposits显示文摘 | Gregory J Holk T Kurtis K | 2003 | Journal of Geochemical Exploration2003，80，23： | 1 |
| 12 | Effects of lithium nitrate admixture on early-age cement hydration显示文摘 | MILLARD M J KURTIS K E | | 0，，4： | 1 |
| 13 | Intedeukin-lbeta and thiobarbitufie acid reactive substance (TBARS) levels after phase I periodontal therapy in patients with chronic periodonfitis显示文摘 | TILTER G KURTIS B SERDAR M | 2001 | J Periodontol2001，72，7： | 1 |
| 14 | Upper urinary tract urothe- lial carcinoma with intratubular spread显示文摘 | Sarungbam J Kurtis B Phillips J | 2014 | Am J Clin Exp Urol2014，2，2： | 1 |
| 15 | Determination of beta-blockers and beta 2-agonists in sewage by solid-phase extraction and liquid chromatography-tandem mass spectrometry显示文摘 | LEE H B KURTIS S THOMAS E P | 2007 | J Chromatogr A2007，1148，2： | 1 |
| 16 | Matrix metal- loproteinase expression in cardiac myocytes following myocardial infarction in the rabbit显示文摘 | ROMANIC A BURNS KURTIS C GOUT B | 2001 | Life Sci2001，68，7： | 1 |
| 17 | 1423 pancreaticoduodenectomies for pancreatic cancer: A single-institution experience显示文摘 | Jordan M. Winter M.D. John L. Cameron M.D. Kurtis A. Campbell M.D. Meghan A. Arnold M.D. David C. Chang Ph.D. M.B.A. M.P.H. JoAnn Coleman C.R.N.P. Mary B. Hodgin C.M.S.R.N. Patricia K. Sauter C.R.N.P. Ralph H. Hruban M.D. Taylor S. Riall M.D. Richard D. | 2006 | Journal of Gastrointestinal Surgery2006，，9： | 1 |
| 18 | Empirical models to ptedict concrete expansion caused by sulfate attack 显示文摘 | KURTIS K MONTEIRO P M MADANAT S | 1997 | ACI Mater J1997，30，3： | 1 |
| 19 | Biochemical quantification of DNA in human articular and septal carti- lage using PicoGreen and Hoechst 33258显示文摘 | MeGowan KB Kurtis MS Lottman LM el al | 2002 | Osteoarthritis Cartilage2002，10，7： | 1 |
| 20 | 1 kW/1 kWh advanced vanadium redox flow battery utilizing mixed acid electrolytes显示文摘 | Soowhan Kim Edwin Thomsen Guanguang Xia Zimin Nie Jie Bao Kurtis Recknagle Wei Wang Vilayanur Viswanathan Qingtao Luo Xiaoliang Wei Alasdair Crawford Greg Coffey Gary Maupin Vincent Sprenkle | 2013 | Journal of Power Sources2013，，： | 1 |
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