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3022篇 您的检索式:作者名="Rowland"
    题名 作者 年代 出处 被引量
1国际学术出版开放式访问(OA):Ⅰ.实践与前沿问题研究进展显示文摘综述当前国际学术出版界开放式访问(Open Access,OA)运动实践和理论研究的部分热点问题。主要讨论OA期刊和OA知识库的概念、实施方式,提高OA文献的可见性和可获取性的若干措施,OA带来的学术文献引用影响力的提高和一些发展趋势。李若溪 黄颖 欧红叶 游中胜 Fytton Rowland 2006编辑学报2006,18,3:30
2Management of necrotizing pancreatitis显示文摘Infection complicating pancreatic necrosis leads to persisting sepsis, multiple organ dysfunction syndrome and accounts for about half the deaths that occur following acute pancreatitis. Severe cases due to gallstones require urgent endoscopic sphincterotomy. Patients with pancreatic necrosis should be followed with serial contrast enhanced computed tomography (CE-CT) and if infection is suspected fine needle aspiration of the necrotic area for bacteriology (FNAB) should be undertaken. Treatment of sterile necrosis should initially be non-operative. In the presence of infection necrosectomy is indicated. Although traditionally this has been by open surgery, minimally invasive procedures are a promising new alternative. There are many unresolved issues in the management of pancreatic necrosis. These include, the use of antibiotic prophylaxis, the precise indications for and frequency of repeat CE-CT and FNAB,and the role of enteral feeding.John Slavin Paula Ghaneh Robert Sutton Mark Hartley Peter Rowlands Conall Garvey Mark Hughes John Neoptolemos 2001World Journal of Gastroenterology2001,7,4:21
3Variability of cell proliferation in the proximal and distal colon of normal rats and rats with dimethylhydrazine induced carcinogenesis显示文摘AIM:To investigate the patterns of cell proliferation in proximal and distal colons in normal rats and rats with1,2-dimethylhydrazine(DMH)induced carcinogenesis using the thymidine analogue bromodeoxyuridine.METHODS:Colonic crypt cell proliferation was immunohistochemically detected using the anti-bromodeoxyuridine Bu20a monoclonal antibody.RESULTS:Marked regional differences were found in both groups.Total labelling index(LI)and proliferative zone size in both normal(8.65±0.34vs7.2±0.45,27.74±1.07vs16.75±1.45)andDMH groups(13.13±0.46vs11.55±0.45,39.60±1.32vs35.52±1.58)were significantly higher in distal than in proximal colon(P<0.05).although the number of cells per proxmal crypt was greater(31.45±0.20vs34.45±0.39,42.68±0.53vs49.09±0.65,P<0.001).Crypt length,total LT and proliferative zone size all increased in both proximal and distal regions of DMH rats compared to normal controls(P<0.0001).In DMH-treated rat colon a shift of labelled cells to higher crypt cell positions was demonstrated distally whist a bi-directional shift was evident proximally(P<0.05).CONCLUSION:Our results show that changes in cell proliferation patterns,as assessed by bromodeoxyuridine uptake,can act as a reliable intermediate marker of colonic cancer formation.Observed differences between proliferation patterns in distal and proximal colon may be associated with the higher incidence of tumors in t he distal colon.Kate E Williamson Brian J Rowlands 2002World Journal of Gastroenterology2002,8,5:12
4中国学术期刊国际传播的观察与思考--旅英华人学者访谈实录分析显示文摘调查了37位旅居英国华人学者查阅使用中文期刊的情况,结果显示总体上对中文期刊利用情况很差,仅工程技术类专业的学者使用较多一些。其原因有:①中文期刊参考价值不大;②对外传播渠道不畅通,服务跟不上;③专业术语和词汇交流有障碍;④因汉语语言载体不被国际学术界认同而造成的偏见和误解;⑤编辑出版中存在问题和不足。针对调查结果,提出中国学术期刊应采取措施充分开放交流渠道,增加文献英文含量,提高国际传播的可见性和可获取性。李若溪 Fytton Rowland Jack Meadows 2008中国科技期刊研究2008,19,1:10
5国际学术出版开放式访问(OA):Ⅱ.开放访问期刊“作者付费模式”的实践与争论显示文摘综述当前国际学术出版界开放访问(OA)运动实践和理论研究的热点问题之一———OA期刊的“作者付费模式”。讨论该经营模式的收费来源和方式,经营成本估算和现行的价格标准。对比了OA期刊与传统期刊的经营模式的区别和利弊,分析了OA期刊的可持续发展存在的问题。李若溪 Fytton Rowland 2006编辑学报2006,18,4:8
6Genomic regions underlying agronomic traits in linseed(Linum usitatissimum L.) as revealed by association mapping显示文摘The extremeclimate of the Canadian Prairies poses a major challenge to improve yield. Although it is possible to breed for yield per se, focusing on yield-related traits could be advantageous because of their simpler genetic architecture.The Canadian flax core collection of 390 accessions was genotyped with 464 simple sequence repeat markers, and phenotypic data for nine agronomic traits including yield, bolls per area, 1,000 seed weight, seeds per boll, start of flowering,end of flowering, plant height, plant branching, and lodging collected from up to eight environments was used for association mapping. Based on a mixed model (principal component analysis (PCA)tkinship matrix (K)), 12 significant marker-trait associations for six agronomic traits were identified.Most of the associations were stable across environments as revealed by multivariate analyses. Statistical simulation for five markers associated with 1000 seed weight indicated that the favorable alleles have additive effects. None of the modern cultivars carried the five favorable alleles and the maximum number of four observed in any accessions was mostly in breeding lines. Our results confirmed the complex genetic architecture of yield-related traits and the inherent difficulties associated with their identification while illustrating the potential for improvement through marker-assisted selection.Braulio J.Soto-Cerda Scott Duguid Helen Booker Gordon Rowland Axel Diederichsen Sylvie Cloutier 2014Journal of Integrative Plant Biology2014,56,1:8
7L-精氨酸对实验性结肠癌的作用与机理显示文摘目的 研究L 精氨酸在Wistar大鼠实验性结肠癌中的作用及其机制。方法 用致癌物1 ,2 二甲基联苯 (DMH)每周 1次皮下注射 2 0周建立大鼠结肠癌模型 ,给予L 精氨酸溶液口服 ,对照组皮下注射EDTA ,大鼠共分为 6组 ,每组 1 8~ 2 0只。 2 2周后处死动物 ,研究肿瘤特性、全血淋巴细胞对有丝分裂素PHA的反应、T细胞亚型 (CD2 ,CD4,CD8)及血浆胃泌素浓度变化。结果 精氨酸可明显降低结肠癌的体积 ,而对结肠腺瘤则无明显差异。早期全程应用精氨酸明显减少侵犯到粘膜下层的腺癌数量 ,刺激淋巴细胞对有丝分裂素的反应并提高T细胞亚型的分布。但精氨酸不改变CD4/CD8比率以及胃泌素的浓度。结论 精氨酸降低实验性结肠癌的生成可能与其非特异性刺激机体淋巴细胞免疫功能有关 ,这种作用在肿瘤发生早期更显著。马清涌 王亚峰 徐军 张梅 BJ Rowlands 2001西安医科大学学报2001,22,6:5
8开放访问的绿色通道:OA档案库的进展概述显示文摘介绍开放访问的绿色通道——OA档案库的发展现状及未来发展的可能模式。其中包括:OA档案库的类型;政府、学术机构、出版商对待OA档案库的态度和政策;OA档案库对作者和出版商的影响;实现的工具及其维护费用,目前OA档案库的数量,存储在其中的文章的数量,在各国的分布状况;档案库未来的可能发展模式;等等。赵军平 李若溪 Fytton Rowland 2007编辑学报2007,19,5:4
9Tetramethylpyrazine stimulates cystic fibrosis transmembrane conductance regulator-mediated anion secretion in distal colon of rodents显示文摘AIM: To investigate the effect of tetramethylpyrazine (TMP), an active compound from Ligustiun Wollichii Franchat, on electrolyte transport across the distal colon of rodents and the mechanism involved.METHODS: The short-circuit current (ISC) technique in conjunction with pharmacological agents and specific inhibitors were used in analyzing the electrolyte transport across the distal colon of rodents. The underlying cellular signaling mechanism was investigated by radioimmunoassay analysis (RIA) and a special mouse model of cystic fibrosis.RESULTS: TMP stimulated a concentration-dependent rise in ISC, which was dependent on both Cl- and HCO3-, and inhibited by apical application of diphenylamine-2,2'-dicarboxylic acid (DPC) and glibenclamide, but resistant to 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate (DIDS). Removal of Na+ from basolateral solution almost completely abolished the ISC response to TMP, but it was insensitive to apical Na+ replacement or apical Na+channel blocker, amiloride. Pretreatment of colonic mucosa with BAPTA-AM, a membrane-permeable selective Ca2+chelator, did not significantly alter the TMP-induced ISC. No additive effect of forskolin and 3-isobutyl-1-methylxanthine (IBMX) was observed on the TMP-induced ISc, but it was significantly reduced by a protein kinase A inhibitor, H89.RIA results showed that TMP (1 mmol/L) elicited a significant increase in cellular cAMP production, which was similar to that elicited by the adenylate cyclase activator, forskolin (10 μmol/L). The TMP-elicited ISC as well as forskolin- or IBMX-induced ISC were abolished in mice with homozygous mutation of the cystic fibrosis transmembrane conductance regulator (CFTR) presenting defective CFTR functions and secretions.CONCLUSION: TMP may stimulate cAMP-dependent and CFTR-mediated Cl- and HCO3- secretion. This may have implications in the future development of alternative treatment for constipation.Qiong He Jin-Xia Zhu Ying Xing Lai-Ling Tsang Ning Yang Dewi Kenneth Rowlands Yiu-Wa Chung Hsiao-Chang Chan 2005World Journal of Gastroenterology2005,11,27:4
10儿童青少年运动员的营养需要显示文摘1.儿童青少年运动员应该食用多样化的食物,其中,蛋白质应占膳食总能量的12%~15%,碳水化合物至少占55%,而脂肪至多占30%。日常生活中如何吃才能满足这些要求呢?膳食指南宝塔提供了一条可行之道。2.有些营养素对热爱运动的儿童青少年运动员非常重要,要保证摄入充足,这些营养素是碳水化合物(包括纤维素)、维生素B_6、维生素D、铁、钙、镁、锌、铬。科学合理、包罗各类食物的平衡膳食,对青少年运动员最大程度地全面摄取各种营养素,满足生长发育和运动训练的需要,是非常必要的。3.鼓励儿童青少年运动员在运动训练前、中、后进行补液,以避免脱水的发生。4.如果膳食合理平衡,就没必要额外补充营养品。Oded Bar-Or Susan Barr Michael Bergeron Ruth Carey Priscilla Clarkson Linda Houtkooper Anita Rivera-Brown Tom Rowland Suzanne Steen 艾华 2001体育科学2001,21,5:3
11Volatile organic compounds in 43 Chinese cities显示文摘Barbara Barletta Simone Meinardi F. Sherwood Rowland Chuen-Yu Chan Xinming Wang Shichun Zou Lo Yin Chan Donald R. Blake 2005Atmospheric Environment2005,,32:3
12Children in Disaster Risk Reduction in Portugal: Policies,Education,and (Non) Participation显示文摘International agencies and scientific research have been calling for the inclusion of children in disaster preparedness and risk reduction, to hear their voices in order to address their specific needs and vulnerabilities and harness their capabilities in terms of building community resilience. This article assesses the roles ascribed to children in policy and education for disaster risk reduction in Portugal. The approach is based on a scoping methodology that encompasses document analysis and interviews with national and local stakeholders and policymakers in the disaster risk reduction field. The research is carried out within the scope of a European funded project, CUIDAR Cultures of Disaster Resilience among Children and Young People. More specifically, the article provides an overview of the discourses on the roles ascribed to children in urban disaster risk reduction(DRR). The authors maintain that although children are often taken as a target group in urban disaster prevention and management, they are seldom considered in terms of active participation in disaster risk reduction programs in the Portuguese context. Nevertheless, our analysis shows that there is a growing awareness of the relevance of active participation by children in order to create successful DRR.Ana Delicado ussara Rowland Susana Fonseca Ana Nunes de Almeida Luísa Schmidt Ana Sofia Ribeiro 2017International Journal of Disaster Risk Science2017,8,3:2
13Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma显示文摘The major type of human liver cancer is hepatocellular carcinoma(HCC), and there are currently many risk factors that contribute to this deadly disease. The majority of HCC occurrences are associated with chronic hepatitis viral infection, and hepatitis B viral(HBV) infection is currently a major health problem in Eastern Asia. Elucidating the genetic mechanisms associated with HBV-induced HCC has been difficult due to the heterogeneity and genetic complexity associated with this disease. A repertoire of animal models has been broadly used to study the pathophysiology and to develop potential treatment regimens for HBVassociated HCC. The use of these animal models has provided valuable genetic information and has been an important contributor to uncovering the factors involved in liver malignant transformation, invasion and metastasis. Recently, transposon-based mouse models are becoming more widely used in liver cancer research to interrogate the genome by forward genetics and also used to validate genes rapidly in a reverse genetic manner. Importantly, these transposon-based rapid reverse genetic mouse models could become crucial in testing potential therapeutic agents before proceeding to clinical trials in human. Therefore, this review will cover the use of transposon-based mouse models toaddress the problems of liver cancer, especially HBVassociated HCC occurrences in Asia.Amy P Chiu Barbara R Tschida Lilian H Lo Branden S Moriarity Dewi K Rowlands David A Largaespada Vincent W Keng 2015World Journal of Gastroenterology2015,21,42:2
14Evidence-based Guidelines From ESPGHAN and NASPGHAN for Helicobacter pylori Infection in Children显示文摘Sibylle Koletzko Nicola L. Jones Karen J. Goodman Benjamin Gold Marion Rowland Samy Cadranel Sonny Chong Richard B. Colletti Thomas Casswall Yoram Elitsur Jeannette Guarner Nicolas Kalach Armando Madrazo Francis Megraud Giuseppina Oderda 2011Journal of Pediatric Gastroenterology and Nutrition2011,,2:2
15辣木籽精油的细胞毒性及其提取方法对化学成分的影响(英文)显示文摘目的:研究水蒸汽蒸馏法(HDE)和无溶剂微波萃取法(SME)对辣木籽精油化学组成的影响,并评估精油的细胞毒性。创新点:比较了不同的提取精油方法对精油的化学成分及其细胞毒性的影响。方法:分别采用HDE和SME两种方法提取辣木籽精油,然后使用气相色谱-质谱法分析其化学成分。通过比较在不同浓度和孵化时间下盐水虾卵的孵化率和幼虾的死亡率来检测精油的细胞毒性。结论:HDE和SME两种方法提取的辣木籽精油分别含有16和26种化学成分,各自占总可识别成分的97.515%和97.816%。因此,SME提取法含有更多的成分。盐水虾卵分别在含有两种精油、海水和氯霉素的样品中孵化24 h后,孵化率分别为60.0%(HDE)、56.7%(SME)、63.3%(海水)和15.0%(氯霉素),精油中的孵化率远高于含有氯霉素的样品的孵化率(P<0.05)。同时,SME和HDE精油对幼虾的半致死量分别为2908.23和3473.63μg/ml(大于1000μg/ml被认为无毒)。因此,两种方法提取的精油可广泛适用于药物、食品防腐剂、抗氧化剂和香料等添加剂。Rowland Monday Ojo KAYODE Anthony Jide AFOLAYAN 2015Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2015,16,8:2
16重新定义博物馆中的物品--中国遗产的井喷显示文摘遗产在近年来成为一个热点,不仅政府层面在积极申遗,而且许多社会力量也加入遗产的申请、保护与重新定义之中,使得遗产在中国呈现出一种井喷状态。如何对这一现象进行理解分析,并对遗产概念进行一种基于中国经验的反思成为当下研究的关注点。文章以与遗产相关的博物馆中物品作为切入点,首先梳理物品在中国传统中的意义及其所激发的情感归属感,然后着眼于当代中国自上而下与自下而上两种遗产实践的分析,以期对遗产与博物馆概念进行反思。罗兰(Michael Rowland)(著) 汤芸(译) 彭文斌(校) 2014西南民族大学学报(人文社会科学版)2014,35,4:2
17A comparative chemical and serological study of the full and particles of foot-and-mouth disease virus 显示文摘Rowlands D J Sangar D V Brown F 1975J Gen Virol1975,26,:2
18Immunological priming with synthetic peptides of foot-and-mouth disease virus 显示文摘Francis M J Fry C M Rowlands D J 1985J Gen Virol1985,66,:2
19Surgical management of intrahepatic cholangiocarcinoma: A 31-year experience显示文摘Mark J. Lieser M. Kevin Barry Charles Rowland Duane M. Ilstrup David M. Nagorney 1998Journal of Hepato - Biliary - Pancreatic Surgery1998,,1:2
20Identification of dehydrin-like proteins responsive to chilling in floral buds of blueberry(Vaccinium section Cyanococcus)显示文摘MUTHALIF M M ROWLAND L J 1994Plant Physiol1994,104,4:1
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