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    题名 作者 年代 出处 被引量
1Mouse models in liver cancer research:A review of current literature显示文摘Primary liver cancer remains one of the most lethal malignancies worldwide. Due to differences in prevalence of etiological factors the incidence of primary liver can-cer varies among the world, with a peak in East-Asia. As this disease is still lethal in most of the cases, research has to be done to improve our understanding of the disease, offering insights for possible treatment options. For this purpose, animal models are widely used, especially mouse models. In this review, we describe the different types of mouse models used in liver cancer research, with emphasis on genetically engineered mice used in this field. We focus on hepatocellular carcinoma (HCC), as this is by far the most common type of primary liver cancer, accounting for 70%-85% of cases.Martijn WH Leenders Maarten W Nijkamp Inne HM Borel Rinkes 2008World Journal of Gastroenterology2008,14,45:16
2ON A FINITENESS THEOREM ABOUT PROBLEMS INVOLVING INEQUALITIES显示文摘ONAFINITENESSTHEOREMABOUTPROBLEMSINVOLVINGINEQUALITIES¥WUWeninn(WUWen-tsun)(InstituteofSystemsScience,AcademiaSinica,Beijing1...WU Wen inn(WU Wen-tsun)(Institute of Systems Science, Academia Sinica, Beijing 100080, China) 1994Systems Science and Mathematical Sciences1994,7,3:8
3[6]-Shogaol inhibits melanogenesis in B16 mouse melanoma cells through activation of the ERK pathway显示文摘Cheng YAO 2013Acta Pharmacologica Sinica2013,34,2:4
4Adjuvant capecitabine plus oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC): 5-year follow-up of an open-label, randomised phase 3 trial显示文摘Sung Hoon Noh Sook Ryun Park Han-Kwang Yang Hyun Cheol Chung Ik-Joo Chung Sang-Woon Kim Hyung-Ho Kim Jin-Hyuk Choi Hoon-Kyo Kim Wansik Yu Jong Inn Lee Dong Bok Shin Jiafu Ji Jen-Shi Chen Yunni Lim Stella Ha Yung-Jue Bang 2014Lancet Oncology2014,,12:3
5Impacts of COVID-19 pandemic on urban park visitation:a global analysis显示文摘The COVID-19 pandemic has resulted in over 33 million confirmed cases and over 1 million deaths globally,as of 1 October 2020.During the lockdown and restrictions placed on public activities and gatherings,green spaces have become one of the only sources of resilience amidst the coronavirus pandemic,in part because of their positive effects on psychological,physical and social cohesion and spiritual wellness.This study analyzes the impacts of COVID-19 and government response policies to the pandemic on park visitation at global,regional and national levels and assesses the importance of parks during this global pandemic.The data we collected primarily from Google’s Community Mobility Reports and the Oxford Coronavirus Government Response Tracker.The results for most countries included in the analysis show that park visitation has increased since February 16th,2020 compared to visitor numbers prior to the COVID-19 pandemic.Restrictions on social gathering,movement,and the closure of workplace and indoor recreational places,are correlated with more visits to parks.Stay-at-home restrictions and government stringency index are negatively associated with park visits at a global scale.Demand from residents for parks and outdoor green spaces has increased since the outbreak began,and highlights the important role and benefits provided by parks,especially urban and community parks,under the COVID-19 pandemic.We provide recommendations for park managers and other decision-makers in terms of park management and planning during health crises,as well as for park design and development.In particular,parks could be utilized during pandemics to increase the physical and mental health and social well-being of individuals.Dehui(Christina)Geng John Innes Wanli Wu Guangyu Wang 2021Journal of Forestry Research2021,32,2:3
6Long-term Results of Spinal Cord Injury Therapy Using Mesenchymal Stem Cells Derived From Bone Marrow in Humans显示文摘Jin Hoon Park Dae Yul Kim Inn Young Sung Gyong Hyo Choi Min Ho Jeon Kwang Kuk Kim Sang Ryong Jeon 2012Neurosurgery2012,,5:2
7Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological study显示文摘Manu L. N. G. Malbrain Davide Chiumello Paolo Pelosi Alexander Wilmer Nicola Brienza Vincenzo Malcangi David Bihari Richard Innes Jonathan Cohen Pierre Singer Andre Japiassu Elizabeth Kurtop Bart L. De Keulenaer Ronny Daelemans Monica Del Turco P. Cosimin 2004Intensive Care Medicine2004,,5:2
8Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I显示文摘Michaela Ulrike Gack Randy Allen Albrecht Tomohiko Urano Kyung-Soo Inn I-Chueh Huang Elena Carnero Michael Farzan Satoshi Inoue Jae Ung Jung Adolfo García-Sastre 2009Cell Host & Microbe2009,,5:2
9Early oral feeding after pancreatoduodenectomy enhances recovery without increasing morbidity显示文摘Arja Gerritsen Roos A. W. Wennink Marc G. H. Besselink Hjalmar C. Santvoort Dorine S. J. Tseng Elles Steenhagen Inne H. M. Borel Rinkes I. Quintus Molenaar 2014HPB2014,,:2
10Comparison of six generalized linear models for occurrence of lightning-induced fires in northern Daxing'an Mountains,China显示文摘The occurrence of lightning-induced forest fires during a time period is count data featuring over-dispersion(i.e., variance is larger than mean) and a high frequency of zero counts. In this study, we used six generalized linear models to examine the relationship between the occurrence of lightning-induced forest fires and meteorological factors in the Northern Daxing'an Mountains of China. The six models included Poisson, negative binomial(NB), zeroinflated Poisson(ZIP), zero-inflated negative binomial(ZINB), Poisson hurdle(PH), and negative binomial hurdle(NBH) models. Goodness-of-fit was compared and tested among the six models using Akaike information criterion(AIC), sum of squared errors, likelihood ratio test, and Vuong test. The predictive performance of the models wasassessed and compared using independent validation data by the data-splitting method. Based on the model AIC, the ZINB model best fitted the fire occurrence data, followed by(in order of smaller AIC) NBH, ZIP, NB, PH, and Poisson models. The ZINB model was also best for predicting either zero counts or positive counts(C1). The two Hurdle models(PH and NBH) were better than ZIP,Poisson, and NB models for predicting positive counts, but worse than these three models for predicting zero counts.Thus, the ZINB model was the first choice for modeling the occurrence of lightning-induced forest fires in this study,which implied that the excessive zero counts of lightninginduced fires came from both structure and sampling zeros.Futao Guo Guangyu Wang John L. Innes Zhihai Ma Aiqin Liu Yurui Lin 2016Journal of Forestry Research2016,27,2:2
11Gamma generalized linear model to investigate the effects of climate variables on the area burned by forest fire in northeast China显示文摘The purpose of this study was to determine a suitable model for investigating the effects of climate factors on the area burned by forest fire in the Tahe forest region, Daxing'an Mountains, in northeast China. The response variables were the area burned by lightningcaused fire, human-caused fire, and total burned area. The predictor variables were nine climate variables collected from the local weather station. Three regression models were utilized, including multiple linear regression, loglinear model(log-transformation on both response and predictor variables), and gamma-generalized linear model.The goodness-of-fit of the models were compared based on model fitting statistics such as R^2, AIC, and RMSE. The results revealed that the gamma-generalized linear model was generally superior to both multiple linear regression model and log-linear model for fitting the fire data. Further,the best models were selected based on the criteria that the climate variables were statistically significant at a = 0.05.The gamma best models indicated that maximum wind speed, precipitation, and days that rainfall greater than0.1 mm had significant impacts on the area burned by the lightning-caused fire, while the mean temperature and minimum relative humidity were the main drivers of the burned area caused by human activities. Overall, the total burned area by forest fire was significantly influenced by days that rainfall greater than 0.1 mm and minimum relative humidity, indicating that the moisture condition of forest stands determine the burned area by forest fire.Futao Guo Guangyu Wang John L. Innes Xiangqing Ma Long Sun Haiqing Hu 2015Journal of Forestry Research2015,26,3:2
12近纳米级Mg(OH)_2及纳米水滑石在阻燃聚合物中的应用显示文摘介绍了阻燃剂氢氧化镁在阻燃聚丙烯和其他热塑性聚合物中最新的一些应用研究结果。经有机改性的纳米合成水滑石和'接近纳米级'的氢氧化镁可以有效提高阻燃性能。氢氧化镁和纳米合成水滑石配合使用,可使复合材料的阻燃效果增强并能大大减少负面影响。James Innes 徐耀学 2007塑料助剂2007,,6:2
13Intranasal immunization with Toxoplasma gondii tachyzoite antigen encapsulated into PLG microspheres induces humoral and cell mediated immunity in sheep 显示文摘Stanley AC Buxton D Innes EA 2004Vaccine2004,22,2930:1
14DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells 显示文摘Arlander S J Greene BT Innes CL 2008Cancer Research2008,68,1:1
15Forest planning using co-ev-olutionary cellular automata显示文摘Mathey E Krcmar J Innes D Tait 2007Forest Ecology and Management2007,239,13:1
16Roles of epithelial cell derived periostin in TGF beta activa- tion,collagen production, and collagen gel elasticity in asthma显示文摘Sidhu S S Yuan S Innes A L Kerr S Woodruff P G Hou L 2010Proc Natl Acad Sci USA2010,107,14:1
17The potential biocontrol agent Pseudomonas antimicrobica inhibits germination of conidia and outgrowth of Botrytis cinerea 显示文摘Walker R Innes C Allan E 2001Letters in Applied Microbiology2001,32,:1
18Within-breath modulation of left ventricular function during normal breathing and positivepressure ventilation in man显示文摘INNES J A DORT S C 1993J Physiol1993,460,1:1
19Den tal resin com posi-tescon ta in ing s ilica-fusedw h iskers-effects ofwh isker-to-sil ica ratioon fractu re toughness and indentation prop-ert ies 显示文摘Xu HH Qu inn JB Sm ith DT 2002Biom aterials2002,23,3:1
20Roles of epithelial cell-derived periostin in TGF-beta activation,collagen production,and collagen gel elasticity in asthma显示文摘Sidhu SS Yuan S Innes AL 0,,:1
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