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| 1 | Non-platinum-based chemotherapy for treatment of advanced gastric cancer:5-fluorouracil,taxanes,and irinotecan显示文摘Despite numerous advances in treatment options,advanced gastric cancer(AGC)remains a major public health issue and the leading cause of cancer-related deaths.Cisplatin is one of the most effective broadspectrum anticancer drugs for AGC and a doublet combination regimen of either cisplatin-based or 5-fluorouracil(5FU)-based chemotherapy is generally used for treatment of patients with AGC.However,there is still no consensus on the best regimen for treating AGC.Recently,various new chemotherapeutic agents,including oral 5FU,taxanes,and irinotecan,have been identified as improving the outcomes for AGC when used as a single agent or in combination with nonplatinum chemotherapy.Nonetheless,it is still unclear whether non-platinum-based chemotherapy is a viable treatment option for patients with AGC.Accordingly,this review focuses on the efficacy and tolerability of non-platinum-based chemotherapy for patients with AGC. | Byung Woog Kang Jong Gwang Kim Oh-Kyoung Kwon Ho Young Chung Wansik Yu | 2014 | World Journal of Gastroenterology2014，20，18： | 5 |
| 2 | Recent advances in chemotherapy for advanced gastric cancer显示文摘Although medical treatment has been shown to improve quality of life and prolong survival,no significant progress has been made in the treatment of advanced gastric cancer(AGC)within the last two decades.Thus,the choice of optimum standard first-line chemotherapy regimen for AGC remains debatable,and most responses to chemotherapy are partial and of short duration,with a median survival of approximately 7-11 mo and survival at 2 years rarely more than 10%.Recently,remarkable progress in tumor biology has led to the development of new agents that target critical aspects of oncogenic pathways.For AGC,several molecular targeting agents are now under evaluation in international randomized studies,and trastuzumab,an anti-HER2 monoclonal antibody,has shown antitumor activity against HER-2 positive AGC.However, this benefit is limited to only about 20%of patients with AGC(patients with HER-2 positive AGC).Therefore,there remains a critical need for both the development of more effective agents and the identification of predictive and prognostic molecular markers to select those patients who will benefit most from specific chemotherapeutic regimens and targeted therapies. | Jong Gwang Kim Ho Young Chung Wansik Yu | 2010 | World Journal of Gastrointestinal Oncology2010，2，7： | 5 |
| 3 | Adjuvant capecitabine plus oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC): 5-year follow-up of an open-label, randomised phase 3 trial显示文摘 | Sung Hoon Noh Sook Ryun Park Han-Kwang Yang Hyun Cheol Chung Ik-Joo Chung Sang-Woon Kim Hyung-Ho Kim Jin-Hyuk Choi Hoon-Kyo Kim Wansik Yu Jong Inn Lee Dong Bok Shin Jiafu Ji Jen-Shi Chen Yunni Lim Stella Ha Yung-Jue Bang | 2014 | Lancet Oncology2014，，12： | 3 |
| 4 | Indications for Early Postoperative Intraperitoneal Chemotherapy of Advanced Gastric Cancer: Results of a Prospective Randomized Trial显示文摘 | Wansik Yu Ilwoo Whang Ho Young Chung Andrew Averbach Paul H. Sugarbaker | 2001 | World Journal of Surgery2001，，8： | 2 |
| 5 | High morbidity in myocardial infarction and heart failure patients after gastric cancer surgery显示文摘AIM:To evaluate to morbidity and mortality differences between 4 underlying heart diseases,myocardial infarction(MI),angina pectoris(Angina),heart failure(HF),and atrial fibrillation(AF),after radical surgery for gastric cancer.METHODS:We retrospectively collected data from 221 patients of a total of 15167 patients who underwent radical gastrectomy and were preoperatively diagnosed with a history of Angina,MI,HF,or AF in 8 hospitals.RESULTS:We find that the total morbidity rate is significantly higher in the MI group(44%) than the Angina(15.7%),AF(18.8%),and HF(23.1%) groups(P < 0.01).Moreover,we note that the risk for postoperative cardiac problems is higher in patients with a history of HF(23.1%) than patients with a historyof Angina(2.2%),AF(4.3%),or MI(6%; P = 0.01).The HF and MI groups each have 1 case of cardiogenic mortality.CONCLUSION:We conclude that MI patients have a higher risk of morbidity,and HF patients have a higher risk of postoperative cardiac problems than Angina or AF. | Sang-Ho Jeong Young-Woo Kim Wansik Yu Sang Ho Lee Young Kyu Park Seong-Heum Park In Ho Jeong Sang Eok Lee Yongwhi Park Young-Joon Lee | 2015 | World Journal of Gastroenterology2015，21，21： | 2 |
| 6 | Prospective randomized trial of early postoperative intraperioneal chemotherapy as an adjuvant to respectable gastric canccr显示文摘 | Wansik Yu Ilwoo Whang Insoo Suh | 1998 | Annals of Surgery1998，228，3： | 1 |
| 7 | Prospective randomized trial of early postoperative intraperitoneal chemotherapy as an adjuvant to resectable gastric cancer显示文摘 | I Whang I Suh | 1998 | Annals of Surgery1998，228，3： | 1 |
| 8 | TP53 codon 72 polymorphism associated with prognosis in patients with advanced gastric cancer treated with paclitaxel and cisplatin显示文摘 | Jong Gwang Kim Sang Kyun Sohn Yee Soo Chae Hong Suk Song Ki-Young Kwon Young Rok Do Min Kyoung Kim Kyung Hee Lee Myung Soo Hyun Won Sik Lee Chang-Hak Sohn Joo Seop Jung Gab Chul Kim Ho Young Chung Wansik Yu | 2009 | Cancer Chemotherapy and Pharmacology2009，，2： | 1 |
| 9 | Prospective randomised trial of early postoperative intraperitoneal chemotherapy as an adjuvant to respectable gastric cancer显示文摘 | Wansik Y Whang I Uh I | 1998 | Ann Surg1998，228，： | 1 |
| 10 | Surgical implications of the posterior gastric artery显示文摘 | Wansik T Whang H | 1990 | Am J Surg1990，159，： | 1 |
| 11 | Prospective randomized trial of early postoperative intraperioneal chemotherapy as an adjuvant to respectable gastric cancer显示文摘 | Wansik Yu Ilwoo Whang Insoo Suh | 1998 | Annals of Surgery1998，228，3： | 1 |
| 12 | Prospective Randomized Trial of Early Postoperative Intraperitoneal chemotherapy as an Adjuvant to Resectable Gastric Cancer显示文摘 | Whang I Fuho I | 1998 | Ann Surg1998，228，3： | 1 |
| 13 | Transient thermomechanical analysis of sliding electrical contacts of elastoplastic bodies, thermal softening, and melting inception显示文摘 | Chen W Wayne Wang Q Jane Wansik Kim | 2009 | ASME Journal of Tribology2009，131，2： | 1 |
| 14 | Isolation and characterization of diazotrophic growth promoting bacteria from rhizosphere of agricultural crops of Korea显示文摘 | Myoungsu Park Chungwoo Kim Jinchul Yang Hyoungseok Lee Wansik Shin Seunghwan Kim Tongmin Sa | 2004 | Microbiological Research2004，，2： | 1 |
| 15 | Preoperative quality of life in patients with gastric cancer 显示文摘 | Hyoam Suk Oh Kyung Kwon Wansik Yu | 2015 | J Gastric Cancer2015，15，2： | 1 |
| 16 | 金属带无级变速器带-带轮的机械损失显示文摘本文研究金属带无级变速器带-带轮的机械损失。根据功率流观点把全部功率损失归因于转矩损失,开发了一个耦合图模型。由实验求得功率损失模型系数。由仿真和实验可以看到,稳态带-带轮损失取决于管压,输入转矩和转速。而瞬态损失则取决于转速,换档速度和惯性矩。 | Wansik Ryu Hyunsoo Kim | 2009 | 传动技术2009，，3： | 0 |
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