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76篇 您的检索式:作者名="Arja"
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1Quanti?cation of Tyrosine Hydroxylase and Erb B4 in the Locus Coeruleus of Mood Disorder Patients Using a Multispectral Method to Prevent Interference with Immunocytochemical Signals by Neuromelanin显示文摘The locus coeruleus(LC) has been studied in major depressive disorder(MDD) and bipolar disorder(BD). A major problem of immunocytochemical studies in the human LC is interference with the staining of the immunocytochemical end-product by the omnipresent natural brown pigment neuromelanin. Here, we used a multispectral method to untangle the two colors: blue immunocytochemical staining and brown neuromelanin.We found significantly increased tyrosine hydroxylase(TH) in the LC of MDD patients—thus validating the method—but not in BD patients, and we did not find significant changes in the receptor tyrosine-protein kinase ErbB4 in the LC in MDD or BD patients. We observed clear co-localization of ErbB4, TH, and neuromelanin in the LC neurons. The different stress-related molecular changes in the LC may contribute to the different clinical symptoms in MDD and BD.Lei Guo Jochem StormmesAND Zheng Fang Qingbin Zhu Rawien Balesar Joop van Heerikhuize Arja Sluiter Dick Swaab Ai-Min Bao 2019Neuroscience Bulletin2019,35,2:2
2优化磁性粒子为基础的系统的DNA纯化方案的重要性显示文摘从复杂生物基质中快速、高效地分离核酸是在获取各种实验的最佳起始原料的重要一步。磁性粒子为基础的操作流程提供了一个快速简单的解决方案,它特别适合用于自动化,在获得纯净和完整的DNA或RNA时以最少的动手时间获得良好的重现性结果。因此,必须优化基于磁珠的纯化流程来达到最高质量与数量的核酸提取。本文介绍了一个自动化、高速、以磁性粒子为基础的纯化系统来实现理想的DNA纯化方案,并考察了不同搅拌速度组合,以及在洗脱步骤的加热效应对DNA纯化数量和质量的影响。Marika SUOMALAINEN Sini SUOMALAINEN Virpi PURO Vuokko KYTNIEMI Arja LAMBERG 2010生命科学仪器2010,8,6:2
3Early oral feeding after pancreatoduodenectomy enhances recovery without increasing morbidity显示文摘Arja Gerritsen Roos A. W. Wennink Marc G. H. Besselink Hjalmar C. Santvoort Dorine S. J. Tseng Elles Steenhagen Inne H. M. Borel Rinkes I. Quintus Molenaar 2014HPB2014,,:2
4Interleukin - 1 Polymor- phisms and intervertebral dise degeneration显示文摘Solovieva S Kouhia S Leino - Arjas P 2004Epidemiology2004,15,5:1
5Endoxylanase Ⅱ from Trichoderma reesei has several isoforms with different isoelectric points显示文摘Arja L Matti S A Nisse K 2000Biotechnology and Applied Biochemistry2000,31,1:1
6Oxidative stress and an- tioxidant enzyme activity in South Indian male smokers with chron- ic obstructive pulmonary disease 显示文摘Arja C Surapaneni KM Raya P 2013Respimlogy2013,18,:1
7The claim reserving problem in non-life insurance : some structural ideas 显示文摘Arjas E 1989ASTIN Bulletin1989,19,2:1
8Evolution of microbiological andchemical parameters during manure and strawco-composting in a drum composting system显示文摘Arja H V Maritta H S 1997Agriculture Ecosystems and Environment1997,66,1:1
9Bayesian mapping of multiple quantitative trait loci from incomplete outbred offspringdata显示文摘Sillanpaa M J Arjas E 1999Genetics1999,151,:1
10Evolution of microbiological and chemical parameters during manure and straw co - composting in a drum composting system 显示文摘ARJA H VUORINEN MARITTA H SAHARINEN 1997Agriculture Ecosystem and Environment1997,66,:1
11Narratives of Men's Experiences in Sport显示文摘Arja Laitinen Arto Tiihonen 1990International Review for the Sociology of Sport1990,25,3:1
12Oxidative stress and an- tioxidant enzyme activity in South Indian male smokers with chronic obstructive pulmonary disease 显示文摘Arja C Surapaneni KM Raya P 2013Respirology2013,18,7:1
13Improving Drawability by Using Variable Blank Holder Force and Pressure in Deep Drawing of Round and Non- symmetric Parts 显示文摘AHMETOGLU M A COREMANS Arja KINZEL Cary L et al 1993SAE Transaction Jounal of Materials & Manufacturing1993,102,:1
14Internet addiction? Potentially problematic use of the internet in a population of 12-18 year-old adolescents 显示文摘Riittakerttu Kaltiala-Heino Tomi Lintonen Arja R 2004Addiction Research and Theory2004,12,:1
15Spectral entropy as a measure of hypnosis in Children显示文摘Jaakko GM Klockars MD Arja Hiller 2006Anesthesiology2006,104,:1
16Frequent computer-related activities increase the risk of neck–shoulder and low back pain in adolescents显示文摘Paula T. Hakala Arja H. Rimpelä Lea A. Saarni Jouko J. Salminen 2006The European Journal of Public Health2006,,:1
17High health‐related quality of life among long‐term survivors of childhood acute lymphoblastic leukemia显示文摘Marika J.Harila JarmoSalo MarjattaLanning IlpoVilkkumaa Arja H.Harila‐Saari 2010Pediatr. Blood Cancer2010,,:1
18Characterization of recombinant human growth differentiation factor-9 signaling in ovarian granulosa cells显示文摘David G. Mottershead Minna M. Pulkki Pranuthi Muggalla Arja Pasternack Minna Tolonen Samu Myllymaa Olexandr Korchynskyi Yoshihiro Nishi Toshihiko Yanase Stan Lun Jennifer L. Juengel Mika Laitinen Olli Ritvos 2007Molecular and Cellular Endocrinology2007,,:1
19Relationships between depressive symptoms and self-reported unintentional injuries:the cross-sectional population-based FIN-D2D survey显示文摘Katariina Korniloff Arja H?kkinen Hannu Koponen 0,,:1
20Claims reserving in continuous time:a nonparametric Bayesian approach 显示文摘Haastrup S Arjas E 1996ASTIN Bulletin1996,26,2:1
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