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| 1 | Grade of donor liver microvesicular steatosis does not affect the postoperative outcome after liver transplantation显示文摘BACKGROUND:The potential effect of graft steatosis on the postoperative liver function is discussed controversially. The present study aimed to evaluate the effect of the donor liver microvesicular steatosis on the postoperative outcome after liver transplantation.METHODS:Ninety-four patients undergoing liver transplantation at the University Hospital Aachen were included in this study. The patient cohort was divided into three groups according to the grade of microvesicular steatosis(MiS):MiS <30%(n=27), MiS 30%-60%(n=41) and MiS >60%(n=26).The outcomes after liver transplantation were evaluated, including the 30-day and 1-year patient and graft survival rates and the incidences of early allograft dysfunction(EAD) and primary nonfunction(PNF). RESULTS:The incidences of EAD and PNF did not differ significantly between the groups. We observed 5 cases of PNF,one occurred in the MiS <30% group and 4 in the MiS 30%-60% group. The 30-day and 1-year graft survivals did not differ significantly between groups. The 30-day patient survival rates were 100% in all groups. The 1-year patient survival rates were 94.4% in the MiS <30% group, 87.9% in the MiS 30%-60% group and 90.9% in the MiS >60% group.CONCLUSION:Microvesicular steatosis of donor livers has no negative effect on the postoperative outcome after liver transplantation. | Anne Andert Tom Florian Ulmer Wenzel Schoning Daniela Kroy Marc Hein Patrick Hamid Alizai Christoph Heidenhain Ulf Neumann Maximilian Schmeding | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，6： | 7 |
| 2 | Pretreatment with Interferon‐γ Enhances the Therapeutic Activity of Mesenchymal Stromal Cells in Animal Models of Colitis显示文摘 | MarjolijnDuijvestein Manon E.Wildenberg Mick M.Welling SimoneHennink IlseMolendijk Vanessa L.van Zuylen TjallingBosse Anne Christine W.Vos Eveline S. M.de Jonge‐Muller HeleneRoelofs Louisevan der Weerd Hein W.Verspaget Willem E.Fibbe Anje A.te Velde Gijs | 2011 | STEM CELLS2011，，10： | 1 |
| 3 | Gastrectomy with isoperistaltic jejunal parallel pouch in a 15-year-old adolescent boy with gastric adenocarcinoma and autosomal recessive agammaglobulinemia显示文摘 | Jan E. Slotta Sabine Heine Anne Kauffels Thomas Krenn Frank Grünhage Mathias Wagner Norbert Graf Martin K. Schilling Jochen Schuld | 2011 | Journal of Pediatric Surgery2011，，9： | 1 |
| 4 | Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case–control studies显示文摘 | Celeste Leigh Pearce Claire Templeman Mary Anne Rossing Alice Lee Aimee M Near Penelope M Webb Christina M Nagle Jennifer A Doherty Kara L Cushing-Haugen Kristine G Wicklund Jenny Chang-Claude Rebecca Hein Galina Lurie Lynne R Wilkens Michael E Carney Mar | 2012 | Lancet Oncology2012，，： | 1 |
| 5 | Mannose-binding lectin and Ficolin-2 gene polymorphisms predispose to cytomegalovirus (re)infection after orthotopic liver transplantation显示文摘 | Bert-Jan F. de Rooij Martha T. van der Beek Bart van Hoek Ann C.T.M. Vossen W. Rogier ten Hove Anja Roos Alexander F. Schaapherder Robert J. Porte Johan J. van der Reijden Minneke J. Coenraad Daniel W. Hommes Hein W. Verspaget | 2011 | Journal of Hepatology2011，，4： | 1 |
| 6 | Characteristics of Recurrent Ventricular Fibrillation Associated With Inferolateral Early Repolarization显示文摘 | Michel Ha?ssaguerre Frederic Sacher Akihiko Nogami Nohiriro Komiya Anne Bernard Vincent Probst Sinikka Yli-Mayry Pascal Defaye Yoshifusa Aizawa Robert Frank Roberto Mantovan Riccardo Cappato Christian Wolpert Antoine Leenhardt Luc de Roy Hein Heidbuchel I | 2009 | Journal of the American College of Cardiology2009，，7： | 1 |
| 7 | Regulation of the growth rate of mouse fibroblasts by IL-3 acti vated mouse born marrow-derived mast cells显示文摘 | Dayton ET Caulfield JP Hein ANN | 1989 | J Im mumol1989，142，： | 1 |
| 8 | Regulation of the growth rate of mouse fibroblast by IL- 3 - activated mouse bone marrow- derived mast cells显示文摘 | Dayton ET Caulfield JP Hein ANN | 1989 | J immunol1989，142，： | 1 |
| 9 | Incidence and clinical findings of benign, inflammatory disease in patients resected for presumed pancreatic head cancer显示文摘 | Thomas M. van Gulik Jacques W.A.J. Reeders Anne Bosma Thybout M. Moojen Nico J. Smits Jan Hein Allema Eric A.J. Rauws G.Johan A. Offerhaus Huug Obertop Dirk J. Gouma | 1997 | Gastrointestinal Endoscopy1997，，5： | 1 |
| 10 | Somatic aberrations of mismatch repair genes as a cause of microsatellite‐unstable cancers显示文摘 | Willemina RR Geurts‐Giele Celine HM Leenen Hendrikus J Dubbink Isabelle C Meijssen Edward Post Hein FBM Sleddens Ernst J Kuipers Anne Goverde Ans MW van den Ouweland Margot GF van Lier Ewout W Steyerberg Monique E van Leerdam Anja Wagner Winand NM Dinjens | 2014 | Pathol2014，，4： | 1 |
| 11 | Preschool Physical Activity and Functional Constipation: The Generation R Study显示文摘 | Lisa M. Driessen Jessica C. Kiefte-de Jong Anne Wijtzes Sanne I. de Vries Vincent W.V. Jaddoe Albert Hofman Hein Raat Henriette A. Moll | 2013 | Journal of Pediatric Gastroenterology and Nutrition2013，，6： | 1 |
| 12 | Population-based frequency of surfactant dysfunction mutations in a native Chinese cohort显示文摘Background: Rare mutations in surfactant-associatedgenes contribute to neonatal respiratory distress syndrome.The frequency of mutations in these genes in the Chinesepopulation is unknown.Methods: We obtained blood spots from the GuangxiNeonatal Screening Center in Nanning, China thatincluded Han (n=443) and Zhuang (n=313) ethnic groups.We resequenced all exons of the surfactant proteins-B(SFTPB), -C (SFTPC), and the ATP-binding cassettemember A3 (ABCA3) genes and compared the frequenciesof 5 common and all rare variants.Results: We found minor differences in thefrequencies of the common variants in the Han andZhuang cohorts. We did not find any rare mutations inSFTPB or SFTPC, but we found three ABCA3 mutationsin the Han [minor allele frequency (MAF)=0.003] and 7 inthe Zhuang (MAF=0.011) cohorts (P=0.10). The ABCA3mutations were unique to each cohort;five were novel.The collapsed carrier rate of rare ABCA3 mutations inthe Han and Zhuang populations combined was 1.3%,which is signifi cantly lower than that in the United States(P<0.001).Conclusions: The population-based frequency ofmutations in ABCA3 in south China newborns is signifi cantlylower than that in United States. The contribution of theserare ABCA3 mutations to disease burden in the south Chinapopulation is still unknown. | Yu-Jun Chen Jennifer Anne Wambach Kelcey DePass Daniel James Wegner Shao-Ke Chen Qun-Yuan Zhang Hillary Heins Francis Sessions Cole Aaron Hamvas | 2016 | World Journal of Pediatrics2016，12，2： | 0 |
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