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| 1 | The first all-season sample set for mapping global land cover with Landsat-8 data显示文摘We report the world's first all-season training and validation sample sets for global land cover classification with Landsat-8 data.Prior to this,such samples were only available at a single date primarily from the growing season.It is unknown how much limitation such a single-date sample has to mapping global land cover in other seasons of the year.To answer this question,we selected available Landsat-8 images from four seasons and collected training and validation samples from them.We compared the performances of training samples in different seasons using Random Forest algorithm.We found that the use of training samples from any individual season would result in the best overall classification accuracy when validated by samples in the same season.The global overall accuracy from combined best seasonal results was 67.2% when classifying the 11 Level-1 classes in the Finer Resolution Observation and Monitoring of Global Land Cover(FROM-GLC) classification system.The use of training samples from all seasons(named all-season training sample set hereafter) produced an overall accuracy of 67.0%.We also tested classification within 10° latitude 60° longitude zones using all-season training subsample within each zone and obtained an overall accuracy of 70.2%.This indicates that properly grouped subsamples in space can help improve classification accuracies.All the results in this study seem to suggest that it is possible to use an all-season training sample set to reach global optimality with universal applicability in classifying images acquired at any time of a year for global land cover mapping. | Congcong Li Peng Gong Jie Wang Zhiliang Zhu Gregory S. Biging Cui Yuan Tengyun Hu Haiying Zhang Qi Wang Xuecao Li Xiaoxuan Liu Yidi Xu Jing Guo Caixia Liu Kwame O. Hackman Meinan Zhang Yuqi Cheng Le Yu Jun Yang Huabing Huang Nicholas Clinton | 2017 | Science Bulletin2017，62，7： | 21 |
| 2 | 3-year Treatment of Tenofovir Alafenamide vs.Tenofovir Disoproxil Fumarate for Chronic HBV Infection in China显示文摘Background and Aims:Tenofovir alafenamide(TAF)has similar efficacy to tenofovir disoproxil fumarate(TDF)but with improved renal and bone safety in chronic hepatitis B patients studied outside of China.We report 3-year results from two phase 3 studies with TAF in China(Clinicaltrials.gov:NCT02836249 and NCT02836236).Methods:Chinese hepatitis B e antigen(HBeAg)-positive and-negative chronic hepatitis B patients with viremia and elevated alanine aminotransferase were randomized 2:1 to TAF or TDF treatment groups and treated in a double-blind fashion for 144 weeks(3 years).Efficacy responses were assessed by individual study while safety was assessed by a pooled analysis.Results:Of the 334 patients(180 HBeAg-positive and 154 HBeAg-negative)randomized and treated,baseline characteristics were similar between groups.The overall mean age was 38 years and 73%were male.The mean HBV DNA was 6.4 log10 IU/mL.The median alanine aminotransferase was 88 U/L,and 37%had a history of antiviral use.At week 144,the proportion with HBV DNA<29 IU/mL was similar among the two groups,with TAF at 83%vs.TDF at 79%,and TAF at 93%vs.TDF at 92%for the HBeAg-positive and-negative patients,respectively.In each study,higher proportions of TAF than TDF patients showed normalized alanine aminotransferase(via the American Association for the Study of Liver Diseases and the China criteria)and showed loss of HBsAg;meanwhile,the HBeAg seroconversion rates were similar.Treatment was well-tolerated among the TAF patients,who showed a smaller median decline in creatinine clearance(−0.4 vs.−3.2 mL/min;p=0.014)and less percentage change in bone mineral density vs.TDF at hip(−0.95%vs.−1.93%)and spine(+0.35%vs.−1.40%).Conclusions:In chronic hepatitis B patients from China,TAF treatment provided efficacy similar to TDF but with better renal and bone safety at 3 years. | Jinlin Hou Qin Ning Zhongping Duan You Chen Qing Xie Fu-Sheng Wang Lunli Zhang Shanming Wu Hong Tang Jun Li Feng Lin Yongfeng Yang Guozhong Gong John FFlaherty Anuj Gaggar Shuyuan Mo Cong Cheng Gregory Camus Chengwei Chen Yan Huang Jidong Jia Mingxiang Zhang GS-US-320-0110 and GS-US-320-0108 China Investigators | 2021 | Journal of Clinical and Translational Hepatology2021，9，3： | 7 |
| 3 | Dynamic contrast-enhanced MR imaging findings of bone metastasis in patients with prostate cancer显示文摘AIM:To evaluate the dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) findings of bone metastasis in prostate cancer patients.METHODS:Sixteen men with a diagnosis of metastatic prostate cancer to bones were examined with DCE-MRI at 1.5 Tesla.The mean contrast agent concentration vs time curves for bone metastasis and normal bone were calculated and K trans and ve values were estimated and compared.RESULTS:An early significant enhancement (wash-out:n=6,plateau:n=8 and persistent:n=2) was detected in all bone metastases (n=16).Bone metastasis from prostate cancer showed significant enhancementand high K trans and ve values compared to normal bone which does not enhance in the elderly population.The mean K trans was 0.101/mmiinn and 0.0051/mmiinn (P < 0.001),the mean ve was 0.141 and 0.0038 (P < 0.001),for bone metastases and normal bone,respectively. | Arda Kayhan Cheng Yang Fatma Nur Soylu Hatice Lakadamyal Ila Sethi Gregory Karczmar Walter Stadler Aytekin Oto | 2011 | World Journal of Radiology2011，3，10： | 5 |
| 4 | Low virological response and high relapse rates in hepatitis C genotype 1 patients with advanced fibrosis despite adequate therapeutic dosing显示文摘 | Wendy S.C. Cheng Stuart K. Roberts Geoffrey McCaughan William Sievert Martin Weltman Darrell Crawford William Rawlinson Philippa S. Marks James Thommes Bishoy Rizkalla Motoko Yoshihara Gregory J Dore | 2010 | Journal of Hepatology2010，，4： | 2 |
| 5 | Vitamin D status does not predict sustained virologic response or fibrosis stage in chronic hepatitis C genotype 1 infection显示文摘 | Matthew T. Kitson Gregory J. Dore Jacob George Peter Button Geoffrey W. McCaughan Darrell H.G. Crawford William Sievert Martin D. Weltman Wendy S. Cheng Stuart K. Roberts | 2012 | Journal of Hepatology2012，，： | 2 |
| 6 | TFE3 Break-apart FISH Has a Higher Sensitivity for Xp11.2 Translocation–associated Renal Cell Carcinoma Compared With TFE3 or Cathepsin K Immunohistochemical Staining Alone: Expanding the Morphologic Spectrum显示文摘 | Qiu Rao Sean R. Williamson Shaobo Zhang John N. Eble David J. Grignon Mingsheng Wang Xiao-jun Zhou Wenbin Huang Puay-Hoon Tan Gregory T. MacLennan Liang Cheng | 2013 | The American Journal of Surgical Pathology2013，，6： | 2 |
| 7 | Differential effects of donor and recipient IL28B and DDX58 SNPs on severity of HCV after liver transplantation显示文摘 | Scott W. Biggins James Trotter Jane Gralla James R. Burton Kiran M. Bambha Jennifer Dodge Megan Brocato Linling Cheng Matt McQueen Lisa Forman Michael Chang Igal Kam Gregory Everson Richard A. Spritz Goran Klintmalm Hugo R. Rosen | 2013 | Journal of Hepatology2013，，5： | 2 |
| 8 | Molecular Genetic Evidence for a Common Clonal Origin of Urinary Bladder Small Cell Carcinoma and Coexisting Urothelial Carcinoma显示文摘 | Liang Cheng Timothy D. Jones Ryan P. McCarthy John N. Eble Mingsheng Wang Gregory T. MacLennan Antonio Lopez-Beltran Ximing J. Yang Michael O. Koch Shaobo Zhang Chong-Xian Pan Lee Ann Baldridge | 2005 | The American Journal of Pathology2005，，5： | 2 |
| 9 | Histologic Grading of Noninvasive Papillary Urothelial Neoplasms显示文摘 | Gregory T. MacLennan Ziya Kirkali Liang Cheng | 2006 | European Urology2006，，4： | 1 |
| 10 | Characterizinghydro-thermal compression behavior of aspen wood strands显示文摘 | Cheng Zhou Gregory D Smith1 Chunping Dai | 2009 | Wood Science2009，63，5： | 1 |
| 11 | α -methylacyl-CoA racemase (P504S)/34 β E12/p63 triple cocktail stain in prostatic adenocarcinoma after hormonal therapy显示文摘 | Ming-Tse Sung Zhong Jiang Rodolfo Montironi Gregory T. MacLennan Roberta Mazzucchelli Liang Cheng | 2007 | Human Pathology2007，，2： | 1 |
| 12 | Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis显示文摘 | Cheng SH Gregory RJ Marshall J | 1990 | Cell1990，63，： | 1 |
| 13 | Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans显示文摘 | Rhee Eugene P Cheng Susan Larson Martin G Walford Geoffrey A Lewis Gregory D McCabe Elizabeth Yang Elaine Farrell Laurie Fox Caroline S O’Donnell Christopher J Carr Steven A Vasan Ramachandran S Florez Jose C Clish Clary B Wang Thomas J Ger | 2011 | Journal of Clinical Investigation2011，，4： | 1 |
| 14 | Clear Cell Papillary Renal Cell Carcinoma: A Distinct Histopathologic and Molecular Genetic Entity显示文摘 | Stefano Gobbo John N. Eble David J. Grignon Guido Martignoni Gregory T. MacLennan Rajal B. Shah Shaobo Zhang Matteo Brunelli Liang Cheng | 2008 | The American Journal of Surgical Pathology2008，，8： | 1 |
| 15 | Quantitative As- sessment of Groundwater Vulnerability Using Index System and Transport Simulation, Huangshuihe Catchment, China 显示文摘 | YU Cheng YAO Ying-ying GREGORY H | 2010 | Science of the Total Environment2010，408，24： | 1 |
| 16 | Transcriptional expression profiles of oral squamous cell carcinomas显示文摘 | Mendez E Cheng CD Gregory Farwell | 2002 | Cancer2002，95，： | 1 |
| 17 | Gastroesophageal Reflux Disease–Associated Esophagitis Induces Endogenous Cytokine Production Leading to Motor Abnormalities显示文摘 | Florian Rieder Ling Cheng Karen M. Harnett Amitabh Chak Gregory S. Cooper Gerard Isenberg Monica Ray Jeffry A. Katz Andrew Catanzaro Robert O’Shea Anthony B. Post Richard Wong Michael V. Sivak Thomas McCormick Manijeh Phillips Gail A. West Joseph E. Willi | 2007 | Gastroenterology2007，，1： | 1 |
| 18 | Diagnosis, evaluation and treatment of carcinoma in situ of the urinary bladder: The state of the art显示文摘 | Sean R. Williamson Rodolfo Montironi Antonio Lopez-Beltran Gregory T. MacLennan Darrell D. Davidson Liang Cheng | 2010 | Critical Reviews in Oncology and Hematology2010，，2： | 1 |
| 19 | Functional identity of proliferating cell nudeal antigen K and a DNA polymerase δ auxiliary protein显示文摘 | Gregory PR Cheng KT Matthewko | 1987 | Nature1987，326，： | 1 |
| 20 | Introduction to Head-Related Transfer Functions (HRTFs): Representations of HRTFs in Time, Frequency, and Space 显示文摘 | Cheng C I Gregory H W | 2001 | Journal of the Audio Engineering Society (S1549-4950)2001，49，4： | 1 |
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