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| 1 | PERSPECTIVES IN MECHANICS OF HETEROGENEOUS SOLIDS显示文摘The Microand Nano-mechanics Working Group of the Chinese Society of Theoretical and Applied Mechanics organized a forum to discuss the perspectives,trends,and directions in mechanics of heterogeneous materials in January 2010.The international journal,Acta Mechanica Solida Sinica,is devoted to all fields of solid mechanics and relevant disciplines in science,technology,and engineering,with a balanced coverage on analytical,experimental,numerical and applied investigations.On the occasion of the 30 th anniversary of Acta Mechanica Solida Sinica,its editor-in-chief,Professor Q.S.Zheng invited some of the forum participants to review the state-of-the-art of mechanics of heterogeneous solids,with a particular emphasis on the recent research development results of Chinese scientists.Their reviews are organized into five research areas as reported in different sections of this paper.§I firstly brings in focus on microand nano-mechanics,with regards to several selective topics,including multiscale coupled models and computational methods,nanocrystal superlattices,surface effects,micromechanical damage mechanics,and microstructural evolution of metals and shape memory alloys.§II shows discussions on multifield coupled mechanical phenomena,e.g.,multi-fields actuations of liquid crystal polymer networks,mechanical behavior of materials under radiations,and micromechanics of heterogeneous materials.In §III,we mainly address the multiscale mechanics of biological nanocomposites,biological adhesive surface mechanics,wetting and dewetting phenomena on microstructured solid surfaces.The phononic crystals and manipulation of elastic waves were elaborated in §IV.Finally,we conclude with a series of perspectives on solid mechanics.This review will set a primary goal of future science research and engineering application on solid mechanics with the effort of social and economic development. | C.Q. Chen J.Z. Cui H.L. Duan X.Q. Feng L.H. He G.K. Hu M.J. Huang Y.Z. Huo B.H. Ji B. Liu X.H. Peng H.J. Shi Q.P. Sun J.X. Wang Y.S. Wang H.P. Zhao Y.P. Zhao Q.S. Zheng W.N. Zou | 2011 | Acta Mechanica Solida Sinica2011，24，1： | 18 |
| 2 | Recent advances in targeting the autotaxin-lysophosphatidate-lipid phosphate phosphatase axis in vivo显示文摘Extracellular lysophosphatidate(LPA) is a potent bioactive lipid that signals through six G-protein-coupled receptors.This signaling is required for embryogenesis,tissue repair and remodeling processes.LPA is produced from circulating lysophosphatidylcholine by autotaxin(ATX),and is degraded outside cells by a family of three enzymes called the lipid phosphate phosphatases(LPPs).In many pathological conditions,particularly in cancers,LPA concentrations are increased due to high ATX expression and low LPP activity.In cancers,LPA signaling drives tumor growth,angiogenesis,metastasis,resistance to chemotherapy and decreased efficacy of radiotherapy.Hence,targeting the ATX-LPA-LPP axis is an attractive strategy for introducing novel adjuvant therapeutic options.In this review,we will summarize current progress in targeting the ATX-LPA-LPP axis with inhibitors of autotaxin activity,LPA receptor antagonists,LPA monoclonal antibodies,and increasing low LPP expression.Some of these agents are already in clinical trials and have applications beyond cancer,including chronic inflammatory diseases. | Matthew G.K. Benesch Xiaoyun Tang Ganesh Venkatraman Raie T. Bekele David N. Brindley | 2016 | The Journal of Biomedical Research2016，30，4： | 9 |
| 3 | 黑格尔和马克思的无限:从无限概念到资本概念显示文摘作者认为,黑格尔善的无限性的本质就在于自身展开,并且生产出和再生产出自身的不同的表现形式,马克思在这方面深受黑格尔的影响,甚至《大纲》的主要基础都是由黑格尔奠定的。但却不能简单地将马克思等同于一般意义上的黑格尔主义者,马克思的发展或者说贡献在于,将黑格尔的基础运用到对资本主义的批判中去,并特别强调了劳动的社会意义。马克思看到了资本主义的根本问题在于资本自身再生产的过程,这一过程表面上看起来与善的无限自身发展过程相类似,却实际上具有恶的无限性的特征,因此这种生产方式是具备摧毁自身的力量的。在这一意义上,马克思对资本主义进行了批判,并提出了真正人的自由和社会自由的问题。 | G.K.勃朗宁 孙大鹏 | 2005 | 世界哲学2005，，6： | 5 |
| 4 | Studies on hypoglycaemic activity of Solanum xanthocarpum Schrad. & Wendl. fruit extract in rats显示文摘 | D.M. Kar L. Maharana S. Pattnaik G.K. Dash | 2006 | Journal of Ethnopharmacology2006，，2： | 3 |
| 5 | Microstructure and properties of a Cu–Cr–Zr alloy显示文摘 | I.S. Batra G.K. Dey U.D. Kulkarni S. Banerjee | 2001 | Journal of Nuclear Materials2001，，2： | 2 |
| 6 | Antioxidant activity of grape seed ( Vitis vinifera ) extracts on peroxidation models in vitro显示文摘 | G.K. Jayaprakasha R.P. Singh K.K. Sakariah | 2001 | Food Chemistry2001，，3： | 2 |
| 7 | Progressive Primary Sclerosing Cholangitis Requiring Liver Transplantation Is Associated With Reduced Need for Colectomy in Patients With Ulcerative Colitis显示文摘 | Udayakumar Navaneethan Preethi G.K. Venkatesh Saurabh Mukewar Bret A. Lashner Feza H. Remzi Arthur J. McCullough Ravi P. Kiran Bo Shen John J. Fung | 2012 | Clinical Gastroenterology and Hepatology2012，，5： | 2 |
| 8 | Impact of Clostridium difficile infection in patients with ulcerative colitis显示文摘 | Revital Kariv Udayakumar Navaneethan Preethi G.K. Venkatesh Rocio Lopez Bo Shen | 2010 | Journal of Crohn’s and Colitis2010，，1： | 2 |
| 9 | Physicochemical and bioactivity of cross-linked chitosan–PVA film for food packaging applications显示文摘 | S. Tripathi G.K. Mehrotra P.K. Dutta | 2009 | International Journal of Biological Macromolecules2009，，4： | 2 |
| 10 | Prise en charge des fractures supracondyliennes en extension stade IV de Lagrange et Rigault显示文摘 | G.K. Akakpo-Numado M. Mal-Lawane M. Belouadah B. Kabore G. Lefort S. Daoud | 2005 | Revue de Chirurgie Orthopedique et Reparatrice de l’appareil moteur2005，，： | 1 |
| 11 | Photoconductive UV detectors on sol–gel-synthesized ZnO films显示文摘 | D. Basak G. Amin B. Mallik G.K. Paul S.K. Sen | 2003 | Journal of Crystal Growth2003，，1： | 1 |
| 12 | Star-anise ( Illicium verum ) and black caraway ( Carum nigrum ) as natural antioxidants显示文摘 | A. Padmashree N. Roopa A.D. Semwal G.K. Sharma G. Agathian A.S. Bawa | 2006 | Food Chemistry2006，，1： | 1 |
| 13 | Stabilization of carbon in composts and biochars in relation to carbon sequestration and soil fertility显示文摘 | N.S. Bolan A. Kunhikrishnan G.K. Choppala R. Thangarajan J.W. Chung | 2012 | Science of the Total Environment2012，，： | 1 |
| 14 | Aerosol sounding with a lidar system based on a DF laser显示文摘 | V.Y. Agroskin B.G. Bravy Y.A. Chernyshev S.A. Kashtanov V.I. Kirianov E.F. Makarov V.G. Papin S.A. Sotnichenko G.K. Vasiliev | 2005 | Applied Physics B2005，，8： | 1 |
| 15 | Residual stresses in laser welded ASTM A387 Grade 91 steel plates显示文摘 | Santosh Kumar A. Kundu K.A. Venkata A. Evans C.E. Truman J.A. Francis K. Bhanumurthy P.J. Bouchard G.K. Dey | 2013 | Materials Science & Engineering A2013，，： | 1 |
| 16 | Decolourization of azo dye methyl red by Saccharomyces cerevisiae MTCC 463显示文摘 | J.P. Jadhav G.K. Parshetti S.D. Kalme S.P. Govindwar | 2006 | Chemosphere2006，，2： | 1 |
| 17 | Numerical and experimental studies of refrigerant circuitry of evaporator coils显示文摘 | S.Y. Liang T.N. Wong G.K. Nathan | 2001 | International Journal of Refrigeration2001，，8： | 1 |
| 18 | Study on refrigerant circuitry of condenser coils with exergy destruction analysis显示文摘 | S.Y. Liang T.N. Wong G.K. Nathan | 2000 | Applied Thermal Engineering2000，，6： | 1 |
| 19 | Laminated high-aspect-ratio microstructures in a conventional CMOS process显示文摘 | G.K. Fedder S. Santhanam M.L. Reed S.C. Eagle D.F. Guillou M.S.-C. Lu L.R. Carley | 1996 | Sensors & Actuators: A Physical1996，，2： | 1 |
| 20 | 应用5%咪喹莫特软膏单一治疗皮肤原位鳞状细胞癌(鲍温病):一项随机、双盲、安慰剂对照试验显示文摘Background: We conducted a double-blind, placebo-controlled, randomized trial to evaluate the preliminary efficacy and safety of imiquimod 5% cream treatment for cutaneous squamous cell carcinoma (SCC) in situ. Methods: In all, 31 patients with biopsy-proven cutaneous SCC in situ were randomly assigned to placebo (vehicle) (n = 16) or imiquimod 5% cream (n = 15) daily for 16 weeks. Patients were assessed at week 28 for the primary end point, resolution of cutaneous SCC in situ. Results: Of the 31 patients enrolled, 3 dropped out. Intention-to-treat analysis revealed 11 of the 15 patients (73% ) in the imiquimod group achieved resolution of cutaneous SCC in situ, with no relapse during the 9-month follow-up period; none in the placebo group achieved resolution (P < .001). Imiquimod 5% cream was generally well tolerated and there were no serious adverse events. Limitations: Topical imiquimod 5% cream has proven to be an effective treatment for cutaneous SCC in situ. However, studies to define the ideal dosing regimen and cost-effectiveness are required before it can be accepted as a recognized therapy. Conclusions: In this controlled trial, patients with cutaneous SCC in situ receiving topical imiquimod 5% cream as monotherapy experienced a high degree of clinical benefit compared with placebo. | Patel G.K. Goodwin R. Chawla M. 吴佳纹 | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，2，8： | 1 |
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