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2篇 您的检索式：作者名="Patel G.K."

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		题名	作者	年代	出处	被引量
	1	应用5%咪喹莫特软膏单一治疗皮肤原位鳞状细胞癌(鲍温病):一项随机、双盲、安慰剂对照试验显示文摘Background: We conducted a double-blind, placebo-controlled, randomized trial to evaluate the preliminary efficacy and safety of imiquimod 5% cream treatment for cutaneous squamous cell carcinoma (SCC) in situ. Methods: In all, 31 patients with biopsy-proven cutaneous SCC in situ were randomly assigned to placebo (vehicle) (n = 16) or imiquimod 5% cream (n = 15) daily for 16 weeks. Patients were assessed at week 28 for the primary end point, resolution of cutaneous SCC in situ. Results: Of the 31 patients enrolled, 3 dropped out. Intention-to-treat analysis revealed 11 of the 15 patients (73% ) in the imiquimod group achieved resolution of cutaneous SCC in situ, with no relapse during the 9-month follow-up period; none in the placebo group achieved resolution (P < .001). Imiquimod 5% cream was generally well tolerated and there were no serious adverse events. Limitations: Topical imiquimod 5% cream has proven to be an effective treatment for cutaneous SCC in situ. However, studies to define the ideal dosing regimen and cost-effectiveness are required before it can be accepted as a recognized therapy. Conclusions: In this controlled trial, patients with cutaneous SCC in situ receiving topical imiquimod 5% cream as monotherapy experienced a high degree of clinical benefit compared with placebo.	Patel G.K. Goodwin R. Chawla M. 吴佳纹	2006	世界核心医学期刊文摘(皮肤病学分册)2006，2，8：	1
	2	异位性皮炎的金黄色葡萄球菌再殖:通过皮肤外机制	Gilani S.J.K. Gonzalez M. Hussain I. G.K. Patel 王琼	2005	世界核心医学期刊文摘(皮肤病学分册)2005，0，6：	0

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