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| 1 | 多器官床旁即时超声在新型冠状病毒肺炎中的应用:国际专家共识显示文摘新型冠状病毒肺炎(简称新冠肺炎,COVID-19)自首次报道以来,已造成全球超一亿人感染,给各国的公共卫生体系造成了巨大威胁。新冠肺炎的临床表现以呼吸系统体征和症状为主,80%的患者症状轻微,约5%为危重症患者,常表现为急性呼吸窘迫综合征(ARDS)。前期,由于缺乏相关研究,面对日益紧迫的临床困境,医务人员不得不借鉴采取一些经验性措施以应对疫情。 | 王臻(译) Arif Hussain Gabriele Via Lawrence Melniker Alberto Goffi Guido Tavazzi Luca Neri Tomas Villen Richard Hoppmann Francesco Mojoli Vicki Noble Laurent Zieleskiewicz Pablo Blanco Irene W.Y.Ma Mahathar Abd.Wahab Abdulmohsen Alsaawi Majid AI Salamah Martin Balik Diego Barca Karim Bendjelid Belaid Bouhemad Pablo Bravo-Figueroa Raoul Breitkreutz Juan Calderon Jim Connolly Roberto Copetti Francesco Corradi Anthony J.Dean AndréDenault Deepak Govil Carmela Graci Young-Rock Ha Laura Hurtado Toru Kameda Michael Lanspa Christian B Laursen Francis Lee Rachel Liu Massimiliano Meineri Miguel Montorfano Peiman Nazerian Bret P.Nelson Aleksandar N.Neskovic Ramon Nogue Adi Osman JoséPazeli Elmo Pereira-Junior Tomislav Petrovic Emanuele Pivetta Jan Poelaert Susanna Price Gregor Prosen Shalim Rodriguez Philippe Rola Colin Royse Yale Tung Chen Mike Wells Adrian Wong Wang Xiaoting Wang Zhen Yaseen Arabi | 2021 | 中国呼吸与危重监护杂志2021，20，2： | 5 |
| 2 | Watt-level and spectrally flat mid-infrared supercontinuum in fluoroindate fibers显示文摘We report on infrared supercontinuum(SC) generation in step-index fluoroindate-based fiber by using an all-fiber laser source. In comparison to widely used ZBLAN fibers for high-power mid-infrared(MIR) SC generation, fluoroindate fibers have multiphoton absorption edges at significantly longer wavelengths and can sustain similar intensities. Recent developments highlighted in the present study allowed the production of fluoroindate fibers with MIR background loss of 2 dB/km, which is similar to or even better than ZBLAN fibers.By using an all-fiber picosecond laser source based on an erbium amplifier followed by a thulium power amplifier,we demonstrate the generation of 1.0 W infrared SC spanning over 2.25 octaves from 1 μm to 5 μm. The generated MIR SC also exhibits high spectral flatness with a 6 dB spectral bandwidth from 1.91 μm to 4.77 μm and an average power two orders of magnitude greater than in previous demonstrations with a similar spectral distribution. | FRANCIS THEBERGE NANCY BERUBE SAMUEL POULAIN SOLENN COXIC LOUIS-RAFAEL ROBICHAUD MARTIN BERNIER REAL VALLEE | 2018 | Photonics Research2018，6，6： | 5 |
| 3 | 西藏多龙矿集区热构造演化历史——来自磷灰石(U-Th)/He的证据显示文摘西藏多龙矿集区是西藏最重要的斑岩-浅成低温热液型矿集区。多龙矿集区经历了多期次的构造抬升-剥蚀事件,成矿后的埋藏-剥蚀历史对矿体的保存至关重要。本文运用磷灰石(U-Th)/He数据对多龙矿集区的低温热年代学进行研究。磷灰石(U-Th)/He年龄平均值分布在85. 1±4. 0Ma到37. 9±2. 5Ma,记录了晚白垩世到古新世、始新世、渐新世的热-构造事件。热历史模拟显示,多龙矿集区主要经历4次冷却事件:Ⅰ) 100~75Ma,冷却速率约为4℃/Myr,剥速率约为0. 16km/Myr,与班公湖-怒江洋的闭合以及拉萨-羌塘地块的碰撞事件有关;Ⅱ) 75~45Ma,冷却速率约为0. 3℃/Myr,剥蚀速率约为0. 01km/Myr,与拉萨-羌塘地块的继续碰撞事件以及由碰撞作用引起的逆冲推覆构造事件有关;Ⅲ) 45~30Ma,冷却速率约为2℃/Myr,剥蚀速率约为0. 08km/Myr,与印度-欧亚大陆的碰撞抬升事件有关;Ⅳ) 30Ma至今,冷却速率约为1℃/Myr,剥蚀速率约为0. 04km/Myr,与渐新世以来印度-欧亚大陆的持续碰撞作用以及渐新世以来青藏高原发育的频繁构造事件有关。多龙矿集区斑岩-浅成低温热液型矿床形成后在强烈的隆升-剥蚀的环境下保存下来,得益于早白垩世美日切错组火山岩的覆盖,由拉萨-羌塘地块碰撞作用引起的逆冲推覆构造引起的上部地层加厚,以及印度-欧亚大陆碰撞事件在多龙矿集区产生的相对较弱的破坏效应。拉萨-羌塘地块碰撞作用引起的地层加厚对多龙矿集区矿床起主要的保护作用。 | 杨欢欢 宋扬 DILLES John H SOUSA Francis DANI?íK Martin 杨超 | 2019 | 岩石学报2019，35，3： | 4 |
| 4 | DMP1 prevents osteocyte alterations,FGF23 elevation and left ventricular hypertrophy in mice with chronic kidney disease显示文摘During chronic kidney disease (CKD),alterations in bone and mineral metabolism include increased production of the hormone fibroblast growth factor 23 (FGF23) that may contribute to cardiovascular mortality.The osteocyte protein dentin matrix protein 1 (DMP1) reduces FGF23 and enhances bone mineralization,but its effects in CKD are unknown.We tested the hypothesis that DMP1 supplementation in CKD would improve bone health,prevent FGF23 elevations and minimize consequent adverse cardiovascular outcomes.We investigated DMP1 regulation and effects in wild-type (WT) mice and the Col4a3^-/- mouse model of CKD.Col4a3^-/- mice demonstrated impaired kidney function,reduced bone DMP1 expression,reduced bone mass,altered osteocyte morphology and connectivity,increased osteocyte apoptosis,increased serum FGF23,hyperphosphatemia,left ventricular hypertrophy (LVH),and reduced survival.Genetic or pharmacological supplementation of DMP1 in Col4a3^-/- mice prevented osteocyte apoptosis,preserved osteocyte networks,corrected bone mass,partially lowered FGF23 levels by attenuating NFAT-induced FGF23 transcription,and further increased serum phosphate.Despite impaired kidney function and worsened hyperphosphatemia,DMP1 prevented development of LVH and improved Col4a3^-/- survival.Our data suggest that CKD reduces DMP1 expression,whereas its restoration represents a potential therapeutic approach to lower FGF23 and improve bone and cardiac health in CKD. | Corey Dussold Claire Gerber Samantha White Xueyan Wang Lixin Qi Connor Francis Maralee Capella Guillaume Courbon Jingya Wang Chaoyuan Li Jian Q. Feng Tamara Isakova Myles Wolf Valentin David Aline Martin | 2019 | Bone Research2019，7，2： | 4 |
| 5 | Lipocalin 2 stimulates bone fibroblast growth factor 23 production in chronic kidney disease显示文摘Bone-produced fibroblast growth factor 23(FGF23)increases in response to inflammation and iron deficiency and contributes to cardiovascular mortality in chronic kidney disease(CKD).Neutrophil gelatinase-associated lipocalin(NGAL or lipocalin 2;LCN2 the murine homolog)is a pro-inflammatory and iron-shuttling molecule that is secreted in response to kidney injury and may promote CKD progression.We investigated bone FGF23 regulation by circulating LCN2.At 23 weeks,Col4a3KO mice showed impaired kidney function,increased levels of kidney and serum LCN2,increased bone and serum FGF23,anemia,and left ventricular hypertrophy(LVH).Deletion of Lcn2 in CKD mice did not improve kidney function or anemia but prevented the development of LVH and improved survival in association with marked reductions in serum FGF23.Lcn2 deletion specifically prevented FGF23 elevations in response to inflammation,but not iron deficiency or phosphate,and administration of LCN2 increased serum FGF23 in healthy and CKD mice by stimulating Fgf23 transcription via activation of cAMP-mediated signaling in bone cells.These results show that kidney-produced LCN2 is an important mediator of increased FGF23 production by bone in response to inflammation and in CKD.LCN2 inhibition might represent a potential therapeutic approach to lower FGF23 and improve outcomes in CKD. | Guillaume Courbon Connor Francis Claire Gerber Samantha Neuburg Xueyan Wang Emily Lynch Tamara Isakova Jodie LBabitt Myles Wolf Aline Martin Valentin David | 2021 | Bone Research2021，9，3： | 4 |
| 6 | Bone Formation and Inflammation in Cardiac Valves显示文摘 | Emile R. Mohler Francis Gannon Carol Reynolds Robert Zimmerman Martin G. Keane Frederick S. Kaplan | 2001 | Circulation: Journal of the American Heart Association2001，，11： | 2 |
| 7 | l:6-Di-4'- chlorophenyldiguanidohexane (hibitane); laboratory investigation of a new antibacterial agent of high potency显示文摘 | Davies GE Francis J Martin AR | 1954 | Br J Pharmacol Chemother1954，9，2： | 1 |
| 8 | Fatty acid analysis of blood serum, seminal plasma, and spermatozoa of normozoospermic vs. Asthernozoospermic males显示文摘 | Julie A. Conquer James B. Martin Ian Tummon Lynn Watson Francis Tekpetey | 1999 | Lipids1999，，8： | 1 |
| 9 | Genomic and transcriptomic analysis of Laccaria bicolor CAZome reveals insights into polysaccharides remodelling during symbiosis establishment显示文摘 | Claire Veneault-Fourrey Carine Commun Annegret Kohler Emmanuelle Morin Raffaella Balestrini Jonathan Plett Etienne Danchin Pedro Coutinho Ad Wiebenga Ronald P. de Vries Bernard Henrissat Francis Martin | 2014 | Fungal Genetics and Biology2014，，： | 1 |
| 10 | Correlation based characterization of phased array components显示文摘 | Francis Soualle Martin Stangl | 2003 | IEEE2003，，： | 1 |
| 11 | Voluven?, a Lower Substituted Novel Hydroxyethyl Starch (HES 130/0.4), Causes Fewer Effects on Coagulation in Major Orthopedic Surgery than HES 200/0.5显示文摘 | Olivier Langeron Martin Doelberg Eng-Than Ang Francis Bonnet Xavier Capdevila Pierre Coriat | 2001 | Anesthesia and Analgesia2001，，4： | 1 |
| 12 | A new high performance liquid chromatography assay for glutamine synthetase and glutamate synthase in plant tissue显示文摘 | FRANCIS MARTIN AKIVA SUZUDI BERTRAN HIREL | 1982 | Analytical Biochemistry1982，125，： | 1 |
| 13 | Expression of aldehyde dehydrogenase 1 as a marker of mammary stem cells in benign and malignant breast lesions of Ghanaian women显示文摘 | Theresa Schwartz Azadeh Stark Judy Pang Baffour Awuah Celina G. Kleer Solomon Quayson Stephanie Kingman Francis Aitpillah Francis Abantanga Evelyn Jiagge Joseph K. Oppong Ernest Osei‐Bonsu Iman Martin Xiaowei Yan Kathy Toy Ernest Adjei Max Wicha Lisa A. N | 2012 | Cancer2012，，3： | 1 |
| 14 | Linear spaces with flag-transitive automophism groups显示文摘 | Francis Buekenhout Anne Delandtsheer Jean Doyen Peter B. Kleidman Martin W. Liebeck Jan Saxl | 1990 | Geometriae Dedicata1990，，1： | 1 |
| 15 | Acquisition profitability and timely loss recognition显示文摘 | Jere R. Francis Xiumin Martin | 2009 | Journal of Accounting and Economics2009，，1： | 1 |
| 16 | Meta-Emotion:How Family Communi-eate Emotionally显示文摘 | Martin Francis A | | 0，，04： | 1 |
| 17 | Satellite-derived parameters for biological modelling in coastal waters: Illustration over the eastern continental shelf of the Bay of Biscay显示文摘 | Francis Gohin Sophie Loyer Michel Lunven Claire Labry Jean-Marie Froidefond Daniel Delmas Martin Huret Alain Herbland | 2004 | Remote Sensing of Environment2004，，1： | 1 |
| 18 | Validation of Melampsora larici-populina reference genes for in planta RT-quantitative PCR expression profiling during time-course infection of poplar leaves显示文摘 | Stéphane Hacquard Claire Veneault-Fourrey Christine Delaruelle Pascal Frey Francis Martin Sébastien Duplessis | 2010 | Physiological and Molecular Plant Pathology2010，，3： | 1 |
| 19 | Poplar and Pathogen Interactions: Insights from Populus Genome-Wide Analyses of Resistance and Defense Gene Families and Gene Expression Profiling显示文摘 | Sebastien Duplessis Ian Major Francis Martin Armand Seguin | 2009 | Critical Reviews in Plant Sciences2009，，5： | 1 |
| 20 | The relative importance of firm incentives versus country factors in the demand for assurance services by private entities 显示文摘 | ] Francis J R Khurana I K Martin X | 2011 | Contemporary Accounting Research2011，28，2： | 1 |
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