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| 1 | Endoscopic and anesthetic feasibility of EUS and ERCP combined in a single session versus two different sessions显示文摘AIM:To discuss the feasibility of single session endoscopic ultrasonography(EUS) to discuss and endoscopic retrograde cholangiopancreatography(ERCP) execution.METHODS:Retrospective endoscopic and anesthetic outcome comparison of performing both EUS and ERCP in a single endoscopic session(Group Ⅰ) versus performing each procedure in two different sessions(Group Ⅱ) was made.The following variables were evaluated:epidemiological variables,American Society of Anesthesiologists Physical Status Classification(ASA) level,procedural time,propofol dose,anesthetic complications,endoscopic complications and diagnostic yield,and therapeutic procedures on both groups.T-student,ChiSquare and Fisher test were used for comparison.RESULTS:We included 39 patients in Group Ⅰ(mean age:69.85 ± 9.25;27 men) and 46 in Group Ⅱ(mean age:67.46 ± 12.57;25 men).Procedural time did not differ significantly between both groups(Group Ⅰvs Group Ⅱ:93 ± 32.78 vs 98.98 ± 38.17;P >0.05) but the dose of propofol differed(Group Ⅰ vs Group Ⅱ:322.28 ± 250.54 mg vs 516.96 ± 289.06 mg;P = 0.001).Three patients had normal findings on both explorations.Three anesthetic complications [O2 desaturation(2),broncoaspiration(1)] and 9 endoscopic complications [pancreatitis(6),bleeding(1),perforation(1),cholangitis(1)] occurred without significant differences between both groups(P > 0.05).We did not find any significant difference regarding age,sex,ASA scale level,diagnostic yield or therapeutic maneuvers between both groups.CONCLUSION:The performance of EUS and ERCP in a single session offers a similar diagnostic and therapeutic yield,does not entail a higher complication risk and requires a significantly smaller dose of propofol for sedation compared with performing each exploration in a different session. | Juan J Vila Marcos Kutz Silvia Goi Miriam Ostiz Edurne Amorena Carlos Prieto Cristina Rodriguez Ignacio Fernández-Urien Francisco J Jiménez | 2011 | World Journal of Gastrointestinal Endoscopy2011，3，3： | 3 |
| 2 | Approach to early-onset colorectal cancer:Clinicopathological,familial,molecular and immunohistochemical characteristics显示文摘AIM:To characterize clinicopathological and familial features of early-onset colorectal cancer(CRC) and compare features of tumors with and without microsatellite instability(MSI).METHODS:Forty-five patients with CRC aged 45 or younger were included in the study.Clinical information,a three-generation family history,and tumor samples were obtained.MSI status was analyzed and mismatch repair genes were examined in the MSI families.Tumors were included in a tissue microarray and an immunohistochemical study was carried out with a panel of selected antibodies.RESULTS:Early onset CRC is characterized by advanced stage at diagnosis,right colon location,low-grade of differentiation,mucin production,and presence of polyps.Hereditary forms represent at least 21% of cases.Eighty-one percent of patients who died during followup showed a lack of expression of cyclin E,which could be a marker of poor prognosis.β-catenin expression was normal in a high percentage of tumors.CONCLUSION:Early-onset CRC has an important familial component,with a high proportion of tumors showing microsatellite stable.Cyclin E might be a poor prognosis factor. | Jose Perea Edurne Alvaro Yolanda Rodríguez Cristina Gravalos Eva Sánchez-Tomé Barbara Rivera Francisco Colina Pablo Carbonell Rogelio González-Sarmiento Manuel Hidalgo Miguel Urioste | 2010 | World Journal of Gastroenterology2010，16，29： | 3 |
| 3 | Age at Onset Should Be a Major Criterion for Subclassification of Colorectal Cancer显示文摘 | José Perea Daniel Rueda Alicia Canal Yolanda Rodríguez Edurne álvaro Irene Osorio Cristina Alegre Bárbara Rivera Joaquín Martínez Javier Benítez Miguel Urioste | 2014 | The Journal of Molecular Diagnostics2014，，1： | 2 |
| 4 | Nonhypoxic pathway mediates the induction of hypoxia inducible factor I alpha invascular smoothmuscle cells显示文摘 | Richard D Edurne B Pouyssegur J | 2000 | J Biol Chem2000，275，26： | 1 |
| 5 | A validated solid - liquid extraction method for the HPLC determination of polyphenols in apple tissues Comparison with pressurised liquid extraction显示文摘 | ROSA M ALEJANDRO B EDURNE C LUIS A BLANCA G FRANCISCA V | 2005 | Talanta2005，，65： | 1 |
| 6 | DRCW-OVO: distance-based relative competence weighting combination for one-vs-one strategy in multi-class problems显示文摘 | MIKEL G ALBERTO F EDURNE B | 2015 | Pattern Recognition2015，48，1： | 1 |
| 7 | New method to assess barley nitrogen nutrition status based on image colour analysis显示文摘 | Miguel Pagola Rubén Ortiz Ignacio Irigoyen Humberto Bustince Edurne Barrenechea Pedro Aparicio-Tejo Carmen Lamsfus Berta Lasa | 2008 | Computers and Electronics in Agriculture2008，，2： | 1 |
| 8 | Aβ increases neural stem cell activity in senescence-accelerated SAMP8 mice显示文摘 | María Díaz-Moreno Rafael Hortigüela Ania Gon?alves Irmina García-Carpio Gemma Manich Edurne García-Bermúdez Mireia Moreno-Estellés César Eguiluz Jordi Vilaplana Carme Pelegrí Mar?al Vilar Helena Mira | 2013 | Neurobiology of Aging2013，，： | 1 |
| 9 | Nonhypoxic pathway mediates the induction of hypoxia-inducible factor-1 alpha in vascular smooth muscle cells 显示文摘 | Richard D Edurne B Pouyssegur J | 2000 | J Biology Chemistry2000，275，26： | 1 |
| 10 | Increased ALK Gene Copy Number and Amplification are Frequent in Non-small Cell Lung Cancer显示文摘 | Marta Salido Lara Pijuan Luz Martínez-Avilés Ana B. Galván Israel Ca?adas Ana Rovira Montserrat Zanui Alejandro Martínez Raquel Longarón Francisco Sole Sergio Serrano Beatriz Bellosillo Murry W. Wynes Joan Albanell Fred R. Hirsch Edurne Arriola | 2011 | Journal of Thoracic Oncology2011，，1： | 1 |
| 11 | Topoisomerase Ⅱ alpha amplification may predict benefit from adjuvant anthrecyclines in HER2 positive early breast cancer显示文摘 | Edurne A Socorro M P Maryou B K | 2007 | Breast Cancer Res Treat2007，106，2： | 1 |
| 12 | Nonhy Poxic Pathway mediates the induction of hypoxia - inducible factor - 1αin Vascular Smooth muscle cells 显示文摘 | Darren E Richard Edurne Berra | 2000 | The Journal of Biological Chemistry2000，275，26： | 1 |
| 13 | Epigenetic regulation of the non‐canonical Wnt pathway in acute myeloid leukemia显示文摘 | VanesaMartín AnaValencia XabierAgirre JoseCervera Edurne SanJose‐Eneriz AmaiaVilas‐Zornoza PaulaRodriguez‐Otero Miguel A.Sanz ConcepciónHerrera AntonioTorres FelipeProsper JoseRomán‐Gómez | 2010 | Cancer Science2010，，2： | 1 |
| 14 | Repetitive DNA hypomethylation in the advanced phase of chronic myeloid leukemia显示文摘 | Jose Roman-Gomez Antonio Jimenez-Velasco Xabier Agirre Juan A. Castillejo German Navarro Edurne San Jose-Eneriz Leire Garate Lucia Cordeu Francisco Cervantes Felipe Prosper Anabel Heiniger Antonio Torres | 2007 | Leukemia Research2007，，： | 1 |
| 15 | The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signaling 显示文摘 | Edurne B | 2006 | EMBO reports2006，7，： | 1 |
| 16 | Significant ec-ological impact on the progression of fluoroquinolone resist-ance in Escherichia coli with increased community use of mox-ifloxacin,levofloxacin and amoxicillin/clavulanic acid显示文摘 | Oscar Cuevas Jesùs Oteo Edurne Lzaro | 2011 | JAntimicrob Chemother2011，66，： | 1 |
| 17 | Effects of trans-10,cis-12 conjugated linoleic acid on cholesterol metabolism in hypercholesterolaemic hamsters显示文摘 | Virginia Navarro M. Teresa Macarulla Alfredo Fernández-Quintela Víctor M. Rodríguez Edurne Simón María P. Portillo | 2007 | European Journal of Nutrition2007，，4： | 1 |
| 18 | Identification and Quantification of Dopamine Receptor 2 in Human Eutopicand Ectopic Endometrium:A Novel Molecular Target for Endometriosis Therapy显示文摘 | Edurne Novella-Maestre Carmen Carda Amparo Ruiz-Sauri | 2010 | Biology of Reproduction2010，83，5： | 1 |
| 19 | Signaling Angiogenesis via p42/p44 MAP Kinase and Hypoxia 显示文摘 | Edurne Berra | 2000 | Biochem Pharmacol2000，60，8： | 1 |
| 20 | Prognostic factors and survival in a prospective cohort of patients with high-grade glioma treated with carmustine wafers or temozolomide on an intention-to-treat basis显示文摘 | Gregorio Catalán-Uribarrena Gaizka Bilbao-Barandica I?igo Pomposo-Gaztelu José Undabeitia-Huertas Edurne Ruiz de Gopegui-Ruiz Lara Galbarriatu-Gutiérrez Manuel Canales-Llantada Jon Aurrecoechea-Obieta Alfonso Igartua-Azkune Guillermo Carbayo-Lozano | 2012 | Acta Neurochirurgica2012，，2： | 1 |
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