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| 1 | Transcriptome and Metabolic Profiling Provides Insigh into Betalain Biosynthesis and Evolution in Mirabilis jalapa显示文摘 | Guy Polturak Uwe Heinig Noam Grossman Maor Battat Dena Leshkowitz Sergey Malitsky liana Rogachev~ and Asaph Aharoni | 2018 | Molecular Plant2018，11，1： | 10 |
| 2 | Getting to the bottom of Taxol biosynthesis by fungi显示文摘t Taxol(paclitaxel)is a highly-oxygenated diterpenoid natural product first isolated from the pacific yew tree(Taxus brevifolia).It is one of the most widely used anticancer drugs.Soon after the discovery of its unique mode of action and the resulting high demand,an extensive search was initiated for alternative sources to replace the slow-growing and scarce pacific yew.Thus far,however,Taxol and related compounds have only been found in the genus Taxus,which comprises a small number of slow-growing plants with a broad but generally isolated geographical distribution.In 1993,Stierle and colleagues reported the independent biosynthesis of Taxol in an endophytic fungus isolated from Taxus brevifolia,which resulted in more than 160 subsequent publications and patents addressing the biosynthesis of Taxol and related taxanes by microorganisms.The literature on fungal taxane synthesis contains numerous inconsistencies,prompting us to thoroughly re-examine Taxol biosynthesis in endophytic fungi associated with Taxus spp.Using a combination of phytochemistry,molecular biology and genome sequencing,we were unable to find any evidence for independent taxane biosynthesis in any of the endophytes,including the isolate described in the original publication(Taxomyces andreanae)and several more recent isolates from Taxus trees.Our findings therefore resolve a long-standing mystery concerning the evolution of a complex terpenoid biosynthetic pathway in two distantly-related organisms. | Uwe Heinig Susanne Scholz Stefan Jennewein | 2013 | Fungal Diversity2013，，3： | 3 |
| 3 | Biological activity of some oxygenated sterols显示文摘 | Kandutsch A A Chem H W Heiniger H J | 1978 | Science1978，201，： | 1 |
| 4 | New- born Wet and Soiled Diaper Counts and Timing of Onset of Lactation as Indicators of Breasffeeding Inadequacy显示文摘 | Nommsen-Rivers L A Heinig M J Cohen R J | 2008 | J Hum Lact2008，24，1： | 1 |
| 5 | Sensitive determination of osehamivir andosehamivir carboxylate in plasma, urine, cerebrospinal fluid and brain by liquid chromatography-tandem mass spectrometry 显示文摘 | HEINIG K BUCHEI I F | 2008 | J Chromatogr B2008，876，1： | 1 |
| 6 | Magnetic beads as interfacial nanoprobes 显示文摘 | WEN H Z HEINIG P | 2004 | Langmuir2004，20，： | 1 |
| 7 | Tissue Doppler imaging of the fetal heart--a new parametric ultrasound technique in prenatal medicine显示文摘 | Steinhard J Heinig J Sehmitz R | 2007 | Ultrasehall Med2007，28，6： | 1 |
| 8 | Determination of Triton X-100ininfluenza vaccine by high-performance liquid chromatogra-phy and capillary electrophoresis显示文摘 | Katja Heinig Carla Vogt | 1997 | Fresenius J AnalChem1997，359，： | 1 |
| 9 | A modular spinal rod linkage system to provide rotational stability显示文摘 | Asher M Carson W Heinig C | 1988 | Spine1988，13，3： | 1 |
| 10 | MR-guided interventional breast procedures Considering vacuum biopsy in particular 显示文摘 | Heinig A Amaya B | 2002 | Eur J Radiol2002，42，： | 1 |
| 11 | Contrast enhanced MRI of the breast: accuracy,value,controversies,solutions显示文摘 | Heywang-Kobrunner SH Viehweg P Heinig A | 1997 | Eur J Radiol1997，24，1： | 1 |
| 12 | Vandermonde factorization and ca- nonical representations of block Hankel matrices 显示文摘 | Feldmann S Heinig G | 1996 | Line- ar Algebra Appl1996，241，： | 1 |
| 13 | Fungal diseases of spruce needles-investigations in Switzerland显示文摘 | Heiniger U | 1990 | Schweizerische Zeitschrift fur Forstwesen1990，141，4： | 1 |
| 14 | One stage vertebrectomy or eggshell proce- dure显示文摘 | Heinig CF Boyd BM | 1985 | Orthop Trans1985，9，11： | 1 |
| 15 | STRIDE:Web server for secondary structure assignment from known atomic coordinates of proteins显示文摘 | HEINIG M FRISHMAN D | 2004 | Nucleic Acids Research2004，32，： | 1 |
| 16 | Transformation techniques for Toeplitz and Toeplitz-plus-Hankel matrices I : transformation显示文摘 | Heinig G Bojanczyk A | 1997 | Linear Al gebra Appl1997，254，： | 1 |
| 17 | Transformation techniques for Toeplitz and Toeplitz-plus-Hankel matrices II : transformation显示文摘 | Heinig G Bojanczyk A | 1998 | Linear Algebra Appl1998，278，： | 1 |
| 18 | Use of ultrasound-guided percutaneous vacuum- assisted breast biopsy for selected difficult indications 显示文摘 | Heywang-Kobrunner SH Heinig A Hellerhoff K | 2009 | Breast J2009，15，4： | 1 |
| 19 | Comparison of vegetative compatibility types in Italian and Swiss subpopulations of Cryphonectria parasitica显示文摘 | CORTESI P RIGLING D HEINIGER U | 1998 | European Journal of Forest Pathology1998，28，3： | 1 |
| 20 | High-efficiency dye- sensitized solar cell with three- dimensional photoanode 显示文摘 | T6treauh N Arsenault l~rie Heiniger LP | 2011 | Nano Letters2011，11，11： | 1 |
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