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| 1 | 氯吡格雷的使用与药物洗脱支架植入后远期临床结果显示文摘背景:近来的冠状动脉内药物洗脱支架研究提示,现行的抗血小板治疗方案可能并不足以预防后期支架内血栓形成。目的:于接受药物洗脱支架(drug-eluting stents,DESs)和裸金属支架(bare-metal stents,BMSs)治疗的冠状动脉病患者中评估氯吡格雷使用与患者远期结果的关系。设计、地点及患者:于连续患者中进行观察性研究。患者于2000年1月1日至2005年7月31日在杜克心脏治疗中心(一家位于北卡罗来纳州达累姆市的三级治疗中心)接受冠状动脉内支架治疗。于6、12、24个月时进行随访,直至2006年9月7日。研究人群包括4666例最初接受BMS(n=3165)或DES(n=1501)经皮冠状动脉介入治疗的患者。对随访6和12个月没有事件(没有死亡、心肌梗死或血管重建手术)的患者进行界标分析(landmark analysis)。在这些时间点上根据支架类型以及自我报告之氯吡格雷的使用情况将患者分为4组:DES使用氯吡格雷组、DES不用氯吡格雷组、BMS使用氯吡格雷组以及BMS不用氯吡格雷组。主要观测指标:随访24个月时死亡、非致命性心肌梗死以及死亡或心肌梗死之复合终点。结果:在6个月时没有事件发生的DES组患者(637例使用、579例未使用氯吡格雷)中,氯吡格雷的使用是随访24个月校正死亡率较低(使用2.0%比未使用5.3%;差异,-3.3%;95%CI,-6.3%至-0.3%;P=0.03)以及死亡或心肌梗死发生率较低(3.1%比7.2%;差异,-4.1%;95%CI,-7.6%至-0.6%;P=0.02)的显著预测指标。然而,在BMS组患者中(417例使用、1976例未用氯吡格雷),死亡(3.7%比4.5%;差异,-0.7%;95%CI,-2.9%至1.4%;P=0.50)以及死亡或心肌梗死发生率(5.5%比6.0%;差异,-0.5%;95%CI,-3.2%至2.2%;P:0.70)没有差异。在12个月随访没有事件发生的DES组患者(252例使用、276例未用氯吡格雷)中,氯吡格雷的使用依然可以预测24个月死亡(0%比3.5%;差异,-3.5%;95%CI,-5.9%至-1.1%;P=0.004)以及死亡或心肌梗死发生率(0%比4.5%;差异,-4.5%;95%CI,-7.1%至-1.9%;P〈0.001)较低。然而,在BMS组患者中(346例使用、1644例未用氯吡格雷),在死亡(3.3%比2.7%;差异,0.6%;95%CI,1.5%至2.8%;P=0.57)以及死亡或心肌梗死(4.7%比3.6%;差异,1.0%;95%CI,-1.6%至3.6%;P=0.44)发生方面,依然没有差异。结论:在接受DES治疗的患者中,延长氯吡格雷的使用可以使死亡以及死亡或心肌梗死的发生率下降。然而,使用氯吡格雷的适宜期限只能通过大型临床随机试验确定。 | Eric L Eisenstein, DBA Kevin J. Anstrom, PhD David F. Kong, MD Linda K. Shaw, MS Robert H. Tuttle, MSPH Daniel B. Mark, MD, MPH Judith M. Kramer, MD, MS Robert A. Harrington, MD David B. Matchar, MD David E. Kandzari, MD 1 Eric D. Peterson, MD, MPH Kevin A. Schulman, MD Robert M. Califf, MD 李呈亿(译) David E. Kandzari, MD | 2007 | 美国医学会杂志(中文版)2007，26，3： | 60 |
| 2 | Impact of postoperative intravenous fluid administration on complications following elective hepato-pancreato-biliary surgery显示文摘Background: The impact of perioperative intravenous fluid administration on surgical outcomes has been documented in literature, but not specifically studied in the context of hepato-pancreato-biliary(HPB) surgery. This study aimed to investigate the impact of postoperative intravenous fluid administration on intensive care unit(ICU), in this subgroup of patients. Methods: A single-center retrospective cohort of 241 HPB patients was assessed, focusing on intravenous fluid administration in ICU, during the first 24 h. Intravenous fluid variables were compared to hospital stay and postoperative complications. Data were assessed using Spearman's correlation test for bivariate correlations and logistic regression for multivariate analysis. Results: The median volume of intravenous fluid administered in the first 24 h postoperatively was 4380 mL, of which 2200 mL was crystalloid, 1500 mL colloid and 680 mL 'other' fluid. Patients with one or more complications had a higher median total intravenous fluid input(4790 vs. 4300 mL), higher colloid volume(20 0 0 vs. 150 0 mL), lower urine output(1595 vs. 1900 mL) and greater overall fluid balance( + 3040 vs. + 2553 mL) than those without complications. There were correlations between total intravenous fluid volume administered( r = 0.278, P < 0.001), intravenous colloid input( r = 0.278, P < 0.001), urine output( r =-0.295, P < 0.001), positive fluid balance( r = 0.344, P < 0.001) and length of hospital stay. Logistic regression model was constructed to predict the occurrence of one or more complications; total intravenous fluid volume and overall fluid balance were both independent significant predictors(OR = 2.463, P = 0.007; OR = 1.001, P = 0.011; respectively). Conclusions: Administration of high volumes of intravenous fluids in the first 24 hours post-HPB surgery, along with higher positive fluid balance is associated with a higher rate of complications and longer hospital stay. Moreover, lower urine output is associated with longer hospital stay. Whether these are the cause of complications or the result of them remains unclear. | Daniel Martin Panagis M.Lykoudis Gabriel Jones David Highton Alan Shaw Sarah James Qiang Wei Giuseppe Fusai | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，5： | 2 |
| 3 | Incremental Prognostic Value of Myocardial Perfusion Single Photon Emission Computed Tomography for the Prediction of Cardiac Death: Differential Stratification for Risk of Cardiac Death and Myocardial Infarction显示文摘 | Rory Hachamovitch Daniel S. Berman Leslee J. Shaw Hosen Kiat Ishac Cohen J. Arthur Cabico John Friedman George A. Diamond | 1998 | Circulation1998，，6： | 2 |
| 4 | The dependency of microstructure and properties of nanostructured coatings on plasma spray conditions 显示文摘 | Leon L Shaw Daniel G | 2000 | Surface and Coatings Technology2000，130，： | 1 |
| 5 | The CT-STAT (Coronary Computed Tomographic Angiography for Systematic Triage of Acute Chest Pain Patients to Treatment) Trial显示文摘 | James A. Goldstein Kavitha M. Chinnaiyan Aiden Abidov Stephan Achenbach Daniel S. Berman Sean W. Hayes Udo Hoffmann John R. Lesser Issam A. Mikati Brian J. O’Neil Leslee J. Shaw Michael Y.H. Shen Uma S. Valeti Gilbert L. Raff | 2011 | Journal of the American College of Cardiology2011，，14： | 1 |
| 6 | Indentation fracture behavior of plasma-sprayed nanostructured Al2O3 - 13 ( wt ) % TiO2 coatings显示文摘 | Luo Hong Daniel Gobennan Leon Shaw | 2003 | Materials Science and Engineering2003，346，： | 1 |
| 7 | Rationale and design of the DeFACTO ( De termination of F ractional Flow Reserve by A natomic C omputed T omographic Angi O graphy) study显示文摘 | James K. Min Daniel S. Berman Matthew J. Budoff Farouc A. Jaffer Jonathon Leipsic Martin B. Leon G.B. John Mancini Laura Mauri Robert S. Schwartz Leslee J. Shaw | 2011 | Journal of Cardiovascular Computed Tomography2011，，5： | 1 |
| 8 | EspA filament-mediated protein translocation into red blood cells显示文摘 | Shaw RK Daniell S Ebel F | 2001 | Cell Microbiol2001，3，： | 1 |
| 9 | ATP citrate lyase inhibition can suppress tumor cell growth显示文摘 | Georgia Hatzivassiliou Fangping Zhao Daniel E. Bauer Charalambos Andreadis Anthony N. Shaw Dashyant Dhanak Sunil R. Hingorani David A. Tuveson Craig B. Thompson | 2005 | Cancer Cell2005，，4： | 1 |
| 10 | The dependency of microstructure and properties of nanostructured coatings on plasma spray condition 显示文摘 | Leon L Shaw Daniel Goberman Stephen Jiang | 2000 | Surface and Coating Technology2000，130，： | 1 |
| 11 | The dependency of microstructure and properties of nanostructured coatings spray conditions 显示文摘 | Shaw L L Goberman Daniel Ren Ruimdng | 2000 | Surf Coat Tech2000，130，： | 1 |
| 12 | Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis显示文摘 | Alice T Shaw Beow Y Yeap Benjamin J Solomon Gregory J Riely Justin Gainor Jeffrey A Engelman Geoffrey I Shapiro Daniel B Costa Sai-Hong I Ou Mohit Butaney Ravi Salgia Robert G Maki Marileila Varella-Garcia Robert C Doebele Yung-Jue Bang Kimary Kulig Pauli | 2011 | Lancet Oncology2011，，11： | 1 |
| 13 | Cumulative Risk, Negative Emotionality, and Emotion Regulation as Predictors of Social Competence in Transition to School: A Mediated Moderation Model显示文摘 | Hyein Chang Elizabeth C. Shelleby JeeWon Cheong Daniel S. Shaw | 2012 | Social Development2012，，4： | 1 |
| 14 | Fractal dimensions of mass estimated from intact and eroded soil aggregates 显示文摘 | Daniel Gimenez Janice L Karmon Adolfo Posadas Richard K Shaw | 2002 | Soil Use and Management2002，64，： | 1 |
| 15 | The Dependency of Microstrueture and Properties of Nanostructured Coatings on Plasma spray conditions显示文摘 | Shaw L Daniel Stephen Jiang You Wang | 2000 | Surface and Coatings Technology2000，130，： | 1 |
| 16 | Isolation and identification of Ornithobacterium rhinotracheale from commercial turkey flocks in the upper Midwest 显示文摘 | Donald C Roepke Alberto Back Daniel P Shaw | 1998 | Avian Dis1998，42，1： | 1 |
| 17 | Characterizing Alzheimer’s disease using a hypometabolic convergence index显示文摘 | Kewei Chen Napatkamon Ayutyanont Jessica B.S. Langbaum Adam S. Fleisher Cole Reschke Wendy Lee Xiaofen Liu Dan Bandy Gene E. Alexander Paul M. Thompson Leslie Shaw John Q. Trojanowski Clifford R. Jack Susan M. Landau Norman L. Foster Danielle J. Harvey Mi | 2011 | Neuroimage2011，，1： | 1 |
| 18 | Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis显示文摘 | Alice T Shaw Beow Y Yeap Benjamin J Solomon Gregory J Riely Justin Gainor Jeffrey A Engelman Geoffrey I Shapiro Daniel B Costa Sai-Hong I Ou Mohit Butaney Ravi Salgia Robert G Maki Marileila Varella-Garcia Robert C Doebele Yung-Jue Bang Kimary Kulig Pauli | 2011 | Lancet Oncology2011，，11： | 1 |
| 19 | Opposing Effects of Retinoic Acid on Cell Growth Result from Alternate Activation of Two Different Nuclear Receptors显示文摘 | Thaddeus T. Schug Daniel C. Berry Natacha S. Shaw Skylar N. Travis Noa Noy | 2007 | Cell2007，，4： | 1 |
| 20 | From Vulnerable Plaque to Vulnerable Patient—Part III: Executive Summary of the Screening for Heart Attack Prevention and Education (SHAPE) Task Force Report显示文摘 | Morteza Naghavi Erling Falk Harvey S. Hecht Michael J. Jamieson Sanjay Kaul Daniel Berman Zahi Fayad Matthew J. Budoff John Rumberger Tasneem Z. Naqvi Leslee J. Shaw Ole Faergeman Jay Cohn Raymond Bahr Wolfgang Koenig Jasenka Demirovic Dan Arking Victoria | 2006 | The American Journal of Cardiology2006，，2： | 1 |
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