|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Role of the endothelium in inflammatory bowel diseases显示文摘Inflammatory bowel diseases(IBD) are a complex group of diseases involving alterations in mucosal immunity and gastrointestinal physiology during both initiation and progressive phases of the disease.At the core of these alterations are endothelial cells,whose continual adjustments in structure and function coordinate vascular supply,immune cell emigration,and regulation of the tissue environment.Expansion of the endothelium in IBD(angiogenesis),mediated by inflammatory growth factors,cytokines and chemokines,is a hallmark of active gut disease and is closely related to disease severity.The endothelium in newly formed or inflamed vessels differs from that in normal vessels in the production of and response to inflammatory cytokines,growth factors,and adhesion molecules,altering coagulant capacity,barrier function and blood cell recruitment in injury.This review examines the roles of the endothelium in the initiation and propagation of IBD pathology and distinctive features of the intestinal endothelium contributing to these conditions. | Walter E Cromer J Michael Mathis Daniel N Granger Ganta V Chaitanya J Steven Alexander | 2011 | World Journal of Gastroenterology2011，17，5： | 10 |
| 2 | Varicella zoster meningitis complicating combined anti-tumor necrosis factor and corticosteroid therapy in Crohn's disease显示文摘Opportunistic viral infections are a well-recognized complication of anti-tumor necrosis factor (TNF) therapy for inflammatory bowel disease (IBD). Cases of severe or atypical varicella zoster virus infection, both primary and latent reactivation, have been described in association with immunosuppression of Crohn's disease (CD) patients. However, central nervous system varicella zoster virus infections have been rarely described, and there are no previous reports of varicella zoster virus meningitis associated with anti-TNF therapy among the CD population. Here, we present the case of a 40-year-old male with severe ileocecal-CD who developed a reactivation of dermatomal herpes zoster after treatment with prednisone and adalimumab. The reactivation presented as debilitating varicella zoster virus meningitis, which was not completely resolved despite aggressive antiviral therapy with prolonged intravenous acyclovir and subsequent oral valacyclovir. This is the first reported case of opportunistic central nervous system varicella zoster infection complicating anti-TNF therapy in the CD population. This paper also reviews the literature on varicella zoster virus infections of immunosuppressed IBD patients and the importance of vaccination prior to initiation of anti-TNF therapy. | Christopher Ma Brennan Walters Richard N Fedorak | 2013 | World Journal of Gastroenterology2013，19，21： | 5 |
| 3 | Update on Cardiovascular Implantable Electronic Device Infections and Their Management: A Scientific Statement From the American Heart Association显示文摘 | Larry M. Baddour Andrew E. Epstein Christopher C. Erickson Bradley P. Knight Matthew E. Levison Peter B. Lockhart Frederick A. Masoudi Eric J. Okum Walter R. Wilson Lee B. Beerman Ann F. Bolger N A. Mark Estes Michael Gewitz Jane W. Newburger Eleanor B. S | 2010 | Circulation2010，，3： | 4 |
| 4 | Effect of hypnotherapy and educational intervention on brain response to visceral stimulus in the irritable bowel syndrome显示文摘 | M. B. O. Lowén E. A. Mayer M. Sj?berg K. Tillisch B. Naliboff J. Labus P. Lundberg M. Str?m M. Engstr?m S. A. Walter | 2013 | Aliment Pharmacol Ther2013，，12： | 4 |
| 5 | Epidemiology of constipation (EPOC) study in the United States: relation of clinical subtypes to sociodemographic features显示文摘 | Walter F Stewart Joshua N Liberman Robert S Sandler Michael S Woods Annette Stemhagen Elsbeth Chee Richard B Lipton Christina E Farup | 1999 | The American Journal of Gastroenterology1999，，12： | 2 |
| 6 | A Novel Line Immunoassay Based on Recombinant Virulence Factors Enables Highly Specific and Sensitive Serologic Diagnosis of Helicobacter pylori Infection显示文摘 | Luca Formichella Laura Romberg Christian Bolz Michael Vieth Michael Geppert Gereon G?ttner Christina N?lting Dirk Walter Wolfgang Schepp Arne Schneider Kurt Ulm Petra Wolf Dirk H. Busch Erwin Soutschek Markus Gerhard | 2013 | Clinical and Vaccine Immunology2013，，11： | 2 |
| 7 | 斯洛伐克西喀尔巴阡山脉内侧Veporicum地区的地球动力学演化序列与菱镁矿和滑石矿床成因(英文)显示文摘本文总结并报导了斯洛伐克西喀尔巴阡山脉内侧的石炭纪岩石中产出的菱镁矿和滑石成因的最新资料.这些矿床赋存于Veporicum构造超单元中和该超单元与Gemericum的接触带中.北部Sinec成矿带是主要的菱镁矿和滑石矿化区,产出的主要矿床有Kokava,Sinec,Samo,Hnsta-Mutnik等矿床.而南部的Ochtina成矿带只产有菱镁矿床,主要矿床包括在Dubrava地体上的Dubrava,Mikov?JedL'vec;Luben韐,Ochtina,Kosice-Bankov,Banisko,Medvedia等矿床.菱镁矿形成于变质M1期石炭系中方解石被白云石和菱镁矿连续交代过程(北矿带成矿温度为280~400℃,南矿带成矿温度为370~420℃;Radvanec&Prochska,2001;Kodera&Radvanec,2002).Permoscythian蒸发卤水提供了Mg.成矿事件和华力西期碰撞后运动有关.拉伸构造和高热流值促使成矿热液系统的产生.滑石矿化则形成于稍晚的不同期变质事件(M2),成矿流体来源也与菱镁矿化不同.构造的、微构造的、变质的以及地质年代学的数据将滑石成矿作用和阿尔卑斯上白垩系的构造地热事件AD2联系在一起.AD2事件是阿尔卑斯碰撞(AD1)地壳加厚和变质核杂岩体起源的结果,体现在地壳不整合面上的区域拉伸,及开放系统中大规模热液流动.这一过程在更靠近Veporic热穹的北带区域(Sinec剪切带)很显著,而向着Veporic热穹的周围部分(南Ochtina带),M2变质过程和块滑石化则逐渐减弱.Sinec剪切带是北Sinec带中突出的AD2-AD3结构,白云石/菱镁矿透镜体(在M1期交代造成的)和相伴随的岩石夹杂在AD1中更坚硬的基底岩石之中.本研究证明了AD2中块滑石化的普遍性,滑石和白云石2形成于拉伸显微构造中(变质过程M2;温度为490~540℃,压力为240~330MPa).在Sinec带中AD3阶段的对偶剪切作用形成了该带中的滑石矿.它是AD2事件从去顶到区域扭压剪切的动力学转变过程的逐步延续.北Sinec带使AD3变形处于由坚硬岩石包围的软岩石的狭窄的剪切带中,而在南Ochtina带中AD3变形产生在由里面漂浮着坚硬碳酸盐块的软的岩石柱中.在Ochtina带中,在AD2和AD3阶段由于M2期较低的P-T条件和变形梯度导致了该区有经济价值的滑石矿化不发育.总之,现有的研究结果能用作阿尔卑斯型地体中菱镁矿和滑石找矿的基本标志. | Zoltán NMETH Walter PROCHASKA Martin RADVANEC Martin KOV■IK Ján MADARAS Peter KOD■RA L'ubomír HRA■KO | 2004 | 岩石学报2004，20，4： | 2 |
| 8 | Seismic behavior of composite RCS frame systems显示文摘 | Miehael N Bugeja Joseph M Bracci Walter P MooreJr | 2000 | Joumal of Structural Engineering2000，126，4： | 1 |
| 9 | Dynamic stress concentrations for an axially loaded strut at discontinuities due to an elliptical hole or double circular notches显示文摘 | WILLIAM A NADER Z WALTER N | 2004 | International Journal of Impact Engineering2004，30，3： | 1 |
| 10 | Gray matter reduction associated with psychopathology and cognitive dysfunction in unipo- lar depression : a voxel - based morphometry study 显示文摘 | VASIC N WALTER H HOSE A | 2008 | J Affect Disord2008，109，12： | 1 |
| 11 | Delphi research:issues raised by a pilot study显示文摘 | Clibbens N Walters S Baird W | 2012 | Nurse Researcher2012，19，2： | 1 |
| 12 | Physical and related sensory properties of a swallowable bolus显示文摘 | Loret C Walter M Pineau N | 2011 | Physiology and Behavior2011，104，5： | 1 |
| 13 | Ethylene vinyl acetate/layered silicate nanocomposites prepared by a surfactant-free method: Enhanced flame retardant and me- chanical pmperties显示文摘 | SHI Y KASHIWAGI T WALTERS R N | 2009 | Polymer2009，50，15： | 1 |
| 14 | Cigarette smoking, dietary habits and genetic polymorphisms in GSTT1, GSTM1 and CYP1A1 metabolic genes: A case-control study in oncohematological diseases显示文摘AIM To analyze the association between oncohematological diseases and GSTT1 /GSTM1 /CYP1A1 polymorphisms, dietary habits and smoking, in an argentine hospitalbased case-control study.METHODS This hospital-based case-control study involved 125 patients with oncohematological diseases and 310 control subjects. A questionnaire was used to obtain sociodemographic data and information about habits. Blood samples were collected, and DNA was extracted using salting out methods. Deletions in GSTT1 and GSTM1 (null genotypes) were addressed by PCR. CYP1A1 MspI polymorphism was detected by PCR-RFLP. Odds ratio(OR) and 95%CI were calculated to estimate the association between each variable studied and oncohematological disease.RESULTS Women showed lower risk of disease compared to men(OR 0.52, 95%CI: 0.34-0.82, P = 0.003). Higher levels of education(> 12 years) were significantly associated with an increased risk, compared to complete primary school or less(OR 3.68, 95%CI: 1.82-7.40, P < 0.001 adjusted for age and sex). With respect to tobacco, none of the smoking categories showed association with oncohematological diseases. Regarding dietary habits, consumption of grilled/barbecued meat 3 or more times per month showed significant association with an increased risk of disease(OR 1.72, 95%CI: 1.08-2.75, P = 0.02). Daily consumption of coffee also was associated with an increased risk(OR 1.77, 95%CI: 1.03-3.03, P = 0.03). Results for GSTT1, GSTM1 and CYP1A1 polymorphisms showed no significant association with oncohematological diseases. When analyzing the interaction between polymorphisms and tobacco smoking or dietary habits, no statistically significant associations that modify disease risk were found. CONCLUSION We reported an increased risk of oncohematological diseases associated with meat and coffee intake. We did not find significant associations between genetic polymorphisms and blood cancer. | María Belén Cerliani Walter Pavicic Juan Antonio Gili Graciela Klein Silvia Saba Silvina Richard | 2016 | World Journal of Clinical Oncology2016，7，5： | 1 |
| 15 | An observational, retrospective analysis of retreatment with Bortezomib for multiple myeloma 显示文摘 | CON N ER TM DONA QD WALTERS IB | 2008 | Clin Lymphoma Myeloma2008，8，3： | 1 |
| 16 | Evaluation of fecal pancreatic elastase-1 as a measure of pancreatic exocrine function in children with cystic fibrosis显示文摘 | Walters MP McGinley N | 2000 | Pediatr Pulmonol2000，29，3： | 1 |
| 17 | Osteopontin Reduces Polyspermy During In Vitro Fertilization of Porcine Oocytes 显示文摘 | Hao Y Mathiaiagan N Walters E | 2006 | Biol Reprod2006，75，5： | 1 |
| 18 | Noninvasive Identification of the Unstable Carotid Plaque显示文摘 | Brajesh K. Lal Robert W. Hobson Meera Hameed Peter J. Pappas Frank T. Padberg Zafar Jamil Walter N. Durán | 2006 | Annals of Vascular Surgery2006，，2： | 1 |
| 19 | Luteinizing hormone-releasing hormoneⅠ(LHRH-Ⅰ)and its metabolite in peripheral tissues显示文摘 | WALTERS K WEGORZEWSKA I N CHIN Y P | 2008 | Exp Biol Med(Maywood)2008，233，2： | 1 |
| 20 | Empowerment for the el- derly 显示文摘 | Walter U Schneider N Plaumann M | 2008 | Gesundheitswesen2008，70，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员