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| 1 | Myofibroblastic cell activation and neovascularization predict native liver survival and development of esophageal varices in biliary atresia显示文摘AIM:To study the relation between collagen 1,α-smooth muscle actin(α-SMA)and CD34 expression and the most essential portoenterostomy(PE)outcomes.METHODS:Liver specimens were obtained at PE from33 biliary atresia(BA)patients for immunohistochemical analysis of collagen 1,α-SMA and CD34.Liver biopsies from 35 organ donors were used as controls.Expression patterns were related to clinical data including age at PE,serum total and conjugated bilirubin concentration at the time of PE and during follow-up,incidence of esophageal varices in follow-up upper gastrointestinal endoscopies,and native liver survival as well as to detailed histopathological findings.RESULTS:Collagen 1(16.4%vs 4.5%,P<0.0001),α-SMA(17.9%vs 4.6%,P<0.0001)and CD34(4.9%vs 3.8%,P=0.017)were markedly overexpressed in BA patients compared with controls.Patients who underwent liver transplantation by age of two years had significantly higher expression of collagen 1(18.6%vs 13.7%,P=0.024),α-SMA(20.4%vs 15.4%,P=0.009)and CD34(5.9%vs 4.0%,P=0.029)at PE compared with native liver survivors.CD34-positive microvessels were identified in the centrizonal region close to central vein in every BA patient.In majority of BA cases(56%)neovascularization was frequent as CD34-positive microvessels were observed in over half of the hepatic lobules.In controls,the CD34-positive microvessels were rare as they were completely absent in 40%and were found in less than 5%of the hepatic lobules in the rest.The difference between BA patients and controls was significant(P<0.0001).Patients who developed esophageal varices by two years had significantly higher expression of CD34 at PE compared with patients without varices(5.6%vs 4.0%,P=0.019).Expression ofα-SMA(r=0.758,P<0.0001)and collagen 1(r=0.474,P=0.016),and the amount of CD34-positive microvessels(r=0.356,P=0.047)were related to patient age at PE.CONCLUSION:Hepatic myofibroblastic cell activation,fibrogenesis and neovascularization are enhanced in BA,progress with increasing PE age and relate to native liver survival and development of esophageal varices. | Janne S Suominen Hanna Lampela Pivi Heikkil Jouko Lohi Hannu Jalanko Mikko P Pakarinen | 2014 | World Journal of Gastroenterology2014，20，12： | 6 |
| 2 | 夏季日最低温度升高对芬兰皮海湖浮游植物群落的影响显示文摘为讨论日最低气温变化对浮游植物群落结构的影响,以位于芬兰的皮海湖为研究对象,选取1987—2013年夏季的监测数据,采用非度量多维尺度法分析浮游植物群落结构与气象要素和理化因子之间的关系.结果表明:皮海湖地区夏季增温趋势明显,尤其是日最低气温增加显著;皮海湖夏季浮游植物群落结构主要受气象要素影响,其中又以日最低气温的影响最显著.这可能是因为浮游植物的许多生理过程存在明显的昼夜节律,日最低气温升高能加强浮游植物的夜间呼吸作用和对营养物质的吸收等,从而影响浮游植物的生长和增殖速率等指标.由于不同物种对温度的适应范围不一致,因此日最低气温升高同样可能影响浮游植物的群落结构. | 费磊 邓建明 秦伯强 朱广伟 左胜鹏 Jouko SARVALA Anne-Mari VENTELA Teija KIRKKALA | 2016 | 湖泊科学2016，28，3： | 4 |
| 3 | DEM simulation of influence of parameters on energy and degree of mixing显示文摘Powder mixing is being modeled using a simulation based on Newtonian mechanics. Variables under consideration include particle friction and the amplitude, frequency, and direction of shaking. Trajectories for each particle were recorded, and a mixing degree was calculated for each simulation, for which the average energy transferred into the powder system was recorded and compared to the resulting mixing degree. Mixing of particles originally located near the bottom was studied separately, as was the mixing of particles near the surface. This study shows that choosing the proper mixing parameters not only enhances the flnal result of mixing, but also yields good results with less strain on the material mixed and on the mixing device. | Simo Siiri Jouko Yliruusi | 2011 | Particuology2011，9，4： | 4 |
| 4 | 北方沼泽地水位下降对全球气候变暖的影响显示文摘自从最后一次冰川消退以来,北方沼泽地(3.46亿hm^2)积存了300~500Pg碳。这些沼泽地在分离二氧化碳(CO_2)的同时,释放了相当数量的甲烷(CH_4)到大气中。正如对高纬地区预报的那样,如果夏季变得更热、更干,未来沼泽地温室气体的平衡将发生变化,随之而来的CH_4排放将减少,而CO_2和N_2O的排放将增加。北部沼泽地水位下降预计将增强温室效应的影响。我们分别在不同营养水平的未排水和排水的沼泽地测量了碳循环的组分,并把这些结果归纳成一个简单的辐射强迫因子,用以评价水位下降对大气的综合影响。在对存于土壤和树木中的碳以及为经营森林而排水引起的水位下降后CO_2、CH_4和N_2O的通量的变化作出测量的基础上,我们提出一个假设,即由气候变化引发的干旱趋势将减弱北方沼泽地对总辐射强迫的影响,这一影响在100年内约为0.1W/m^2。CH_4排放的减少,沼泽地碳储量的微小变化和树木生物量储存的增加都将导致这一变化。 | Jukka Laine Jouko Silvola Kimmo Tolonen Jukka Alm Hannu Nyknen Harri Vasander Tapani Sallantaus Ilkka Savolainen Jukka Sinisalo Pertti J.Martikainen 钱云 | 1996 | 人类环境杂志1996，25，3： | 4 |
| 5 | 海冰热力模式的辐射参数化方案在渤海和波罗的海应用的比较显示文摘研究了海冰热力模式中的各种辐射参数化方案,对比了模式计算的太阳短波辐射、大气长波辐射以及海冰热力变化,并利用渤海和波罗的海观测资料进行比较和误差分析.冬季大部分时间太阳短波辐射对海冰热力过程的作用有限.简单计算方案一般满足海冰模式要求.误差主要受云和冰雪表面与大气之间的多重反射影响.长波辐射对表面热平衡和海冰质量变化起重要作用.长波辐射参数化方案的计算结果受环境因素影响.云量参数化有待进一步改进.海冰模式计算结果的精度与长波辐射计算精度有一致性. | 张占海 程斌 LAUNIAI NEN Jouko 吴辉碇 刘煜 | 2006 | 海洋学报2006，28，4： | 4 |
| 6 | 应用于大型浆厂的现代碱回收炉技术显示文摘在过去的十年中,化学木浆年均增产量为每年2-3百万吨.原因是新厂的建设和旧厂的扩产.这些新厂项目中主要是以人工种植的桉木为原料.新碱炉的特点是:产量高、环保好、尾气排放少、能够燃烧处理高、低浓臭气.当建设那些新的纸浆生产线时,新技术的发展使得利用规模经济的优势成为可能.很明显,单台碱炉的生产能力必须随着单条生产线产量的增加而增加.本文将介绍在斯堪的纳维亚、东南亚和南美洲几台超大型碱回收炉的运行经验以及使规模不断提高成为可能的碱回收炉技术的发展.本文还列举了最新的碱炉技术,它包括除过黑夜燃烧外还可以处理来自制浆厂的高、低浓臭气以及从溶解槽来的湿汽.本文不但阐述燃烧更高黑液固形物浓度的新技术,还有最近十五年积累的大型碱炉构造设计经验和运行经验. | Kari Haaga Jouko Putkonen | 2004 | 中国造纸学报2004，19，z1： | 3 |
| 7 | Inter-comparisons of thermodynamic sea-ice modeling results using various parameterizations of radiative flux显示文摘Radiative fluxes are of primary importance in the energy and mass balance of the sea-ice cover. Various parameterizations of the radia- tive fluxes are studied in a thermodynamic sea-ice model. Model outputs of the surface radiative and heat fluxes and mass balance are compared with observations. The contribution of short-wave radiation is limited to a long part of winter. Therefore, simple schemes are often sufficient. Errors in estimations of the short-wave radiation are due mainly to cloud effects and occasionally to multi-reflection between surface and ice crystals in the air. The long-wave radiation plays an important role in the ice surface heat and mass balance during most part of a winter. The effect of clouds on the accuracy of the simple radiative schemes is critical, which needs further atten- tion. In general, the accuracy of an ice model depends on that of the radiative fluxes. | ZHANG Zhanhai CHENG Bin LAUNIAINEN Jouko WU Huiding LIU Yu | 2006 | Acta Oceanologica Sinica2006，25，1： | 3 |
| 8 | Fluxes of methane, carbon dioxide and nitrous oxide in boreal lakes and potential anthropogenic effects on the aquatic greenhouse gas emissions显示文摘 | Jari T. Huttunen Jukka Alm Anu Liikanen Sari Juutinen Tuula Larmola Taina Hammar Jouko Silvola Pertti J. Martikainen | 2003 | Chemosphere2003，，3： | 2 |
| 9 | Effect of the Molecular Structure of Polymer Dispersants on Limestone Suspension Properties in Fine Grinding显示文摘 | Katja Ohenoja Juha Saari Mirja Illikainen Jouko Niinimaeki | 2013 | Journal of Chemistry and Chemical Engineering2013，7，7： | 2 |
| 10 | The Role of Heart Rate Variability in Risk Stratification for Adverse Postoperative Cardiac Events显示文摘 | Timo Laitio Jouko Jalonen Tom Kuusela Harry Scheinin | 2007 | Anesthesia & Analgesia2007，，6： | 2 |
| 11 | measurement and error compensation of multi-axis machine tools显示文摘 | Mahbubur Rahman Jouko Heikkala Kauko Lappalainen Modeling | 2000 | Internationl Journal of Machine Tools & Manufacture2000，40，： | 1 |
| 12 | Social and Developmental Predictors of Optimism from Infancy to Early Adulthood显示文摘 | Ellen Ek Jouko Remes Ulla Sovio | 2004 | Social Indicators Research2004，，2： | 1 |
| 13 | Power consumption and fiber development in a TMP Refiner plate gap: comparison of LE-and standard refiner segments显示文摘 | Mirja Illikainen Esko Harkonen Jouko Niinimaki | 2007 | Finland2007，，： | 1 |
| 14 | Prediction of physicochemical properties based on neural network modeling 显示文摘 | Jyrki Taskinen Jouko Yliruusi | 2003 | Adv Drug Delivery Rev2003，55，： | 1 |
| 15 | The ultrastructure of spruce kraft pulps studied by atomic force microscopy(AFM) and X-ray photoelectron spectroscopy(XPS)显示文摘 | Johanna Gustafsson Laura Ciovica Jouko Peltonen | 2005 | Polymer2005，44，： | 1 |
| 16 | Microbe repelling coated stainless steel analysed by field emission scanning electron microscopy and physicochemical methods显示文摘 | Mari Raulio Mikael J?rn Juhana Ahola Jouko Peltonen Jarl B. Rosenholm Sanna Tervakangas Jukka Kolehmainen Timo Ruokolainen Pekka Narko Mirja Salkinoja-Salonen | 2008 | Journal of Industrial Microbiology & Biotechnology2008，，7： | 1 |
| 17 | Oral ascorbic acid increases plasma oestradiol during postmenopausal hormone replacement therapy显示文摘 | Tarja Vihtam?ki Jouko Parantainen Anna-Maija Koivisto Timo Mets?-Ketel? Risto Tuimala | 2002 | Maturitas2002，，2： | 1 |
| 18 | Measurement and Error Compensation of Multi-axis Machine Tools Part Ⅰ:Theory显示文摘 | Mahbubur R Jouko H Kauko L | 2000 | Internationl Journal of Machine Tools & Manufacture2000，，40： | 1 |
| 19 | Apolipoprotein A-I, apolipoprotein B, and apolipoprotein B /apolipopro- tein A-I ratio:Reference intervals compared with values in different pathophysiological conditions from the FINRISK 2007 study显示文摘 | JAANA L JOUKO S GEORG A | 2011 | Clinica Chimica Acta2011，412，： | 1 |
| 20 | What factors control planktonic ciliates during summer in a highly eutrophic lake?显示文摘 | Krzysztof Wiackowski Anne-Mari Ventel? Marianne Moilanen Vesa Saarikari Kristiina Vuorio Jouko Sarvala | 2001 | Hydrobiologia (-)2001，，1： | 1 |
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