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| 1 | Comparison of clinical outcomes between femtosecond laser-assisted versus conventional phacoemulsification显示文摘Background:To compare femtosecond laser-assisted versus conventional phacoemulsification in terms of visual and refractive outcomes,cumulative dissipated energy,anterior chamber inflammation and endothelial cell loss.Methods:In this retrospective cohort study,records of eyes that underwent femtosecond laser-assisted cataract surgery(FLACS)or conventional phacoemulsification(CP)were reviewed.The Victus femtosecond laser(Bausch and Lomb,Germany)was used to carry out corneal incisions,anterior capsulotomy,and lens fragmentation in FLACS procedures.Manifest refraction spherical equivalence(MRSE),uncorrected distance visual acuity(UDVA),corrected distance visual acuity(CDVA),cumulative dissipated energy(CDE),postoperative cells and flare and endothelial cell count data were collected.Subgroup analysis of the visual acuity tests was performed based on the type of intraocular lens implanted(monofocal,monofocal toric,multifocal,multifocal toric,accommodating).Results:A total of 735 eyes were included in the study(296 eyes for the FLACS group and 439 eyes for the CP group).At one year follow-up,120 eyes comprised the FLACS group and 265 eyes for the CP group.MRSE in the FLACS group was−0.16±0.58 D and−0.20±0.52 D in the CP group(P=0.50).UDVA in the FLACS group was 20/25(mean logMAR 0.12±0.13)and 20/25(mean logMAR 0.11±0.13)in the CP group(P=0.48).CDVA was 20/20(mean logMAR 0.03±0.07)in the FLACS group and 20/20(mean logMAR 0.02±0.06)in the CP group(P=0.15).No statistically significant trend was seen for FLACS versus CP by intraocular type for visual acuity.CDE for the different cataract grades ranged from 6.97±5.74 to 29.02±16.07 in the FLACS group and 7.59±6.42 to 35.69±18.30 in the CP group.The FLACS group was significantly lower for post-operative central corneal edema(P=0.05),cells and flare(P=0.01),and endothelial cell loss(P=0.04).Conclusions:Femtosecond laser-assisted cataract surgery and conventional phacoemulsification had similar refractive and visual outcomes.Phacoemulsification energy,anterior chamber inflammation and corneal endothelial cell loss were less in the femtosecond laser group. | Robert Edward Ty Ang Michelle Marie Salcedo Quinto Emerson Marquez Cruz Mark Christian Reyes Rivera Gladness Henna Austria Martinez | 2018 | Eye and Vision2018，5，1： | 10 |
| 2 | Overexpression of HSP27 and HSP70 is associated with decreased survival among patients with esophageal adenocarcinoma显示文摘BACKGROUND Overexpression of heat shock proteins(HSPs) is associated with several malignancies and contributes to the development, progression, and metastasis of cancer, in addition to the inhibition of cellular death. In recent years, there has been active research into using HSP inhibitors in several malignancies. Due to the poor prognosis of esophageal adenocarcinoma(EAC), it would be valuable to find new biomarkers for the development of cancer treatments.AIM To evaluate the expressions of HSP27 and HSP70 and their effect on survival in EAC.METHODS Immunohistochemical analyses and evaluations of HSP27 and HSP70 expression were performed on all available samples from 93 patients diagnosed with EACbetween 1990 and 2007 at two university hospitals. Fifteen cases with Barrett's metaplasia and 5 control cases from the same patient population were included in the analysis. HSP expression was quantitatively assessed and classified as high or low. Kaplan-Meier analyses and Cox regression models adjusting for age and sex as well as tumor site, stage, and grade were used to evaluate the effect on survival.RESULTS Tumor stage and surgical treatment were the main prognostic factors. High HSP27 expression in cancer cases was a strong negative predictive factor, with a mean survival of 23 mo compared to the 49 mo in cases with a low expression(P= 0.018). The results were similar for HSP70, with a poorer survival of 17 mo in cases with high HSP70 expression, in contrast to 40 mo(P = 0.006) in cases with a low expression. A Cox regression survival analysis was performed, adjusting for possible confounding factors, and higher HSP27 and HSP70 expressions remained an independent negative prognostic factor. The HSPs' correlation with survival was not affected by cancer treatments. When the analysis was adjusted for all factors, the odds ratios for HSP27 and HSP70 were 3.3(CI: 1.6–6.6, P =0.001) and 2.2(CI: 1.2–3.9, P = 0.02), respectively.CONCLUSION HSP27 and HSP70 overexpression is associated with poor survival in EAC, which is, to the best of our knowledge, reported for the first time. | Henna K S?derstr?m Juha T Kauppi Niku Oksala Timo Paavonen Leena Krogerus Jari R?s?nen Tuomo Rantanen | 2019 | World Journal of Clinical Cases2019，7，3： | 7 |
| 3 | Overlap Syndrome of Asthma and COPD Predicts Low Quality of Life显示文摘 | Paula Kauppi Henna Kupiainen Ari Lindqvist Lauri Tammilehto Maritta Kilpel? inen Vuokko L. Kinnula Tari Haahtela Tarja Laitinen | 2011 | Journal of Asthma2011，，3： | 2 |
| 4 | Contribution of fibronectin - binding protein to pathogenesis of Streptococcus suis serotype 2 显示文摘 | Astrid de G Henna B Robin V | 2002 | Infect Imm2002，70，3： | 1 |
| 5 | Care recipients and family members per- ceptions of quality of older people care, a comparison of home- based care and nursing homes显示文摘 | Henna H JudithEA | 2010 | Journal of clinical nursing2010，24，7： | 1 |
| 6 | 显示文摘 | Henna V | 2002 | European Journal of Pharmaomtieal Sciences2002，16，： | 1 |
| 7 | Hormonal cryptorchidism therapy: Systematic review with metanalysis of randomized clinical trials显示文摘 | Henna MR Del - Nero RG Sampaio CZ | 2004 | Pediatr Surg Int2004，20，5： | 1 |
| 8 | Effect of-linolenic acid rich Camelina sativa oil on serum fatty acid composition and serum lipids in hypercholesterolemic subjects显示文摘 | Henna M Karvonen Antti Aro Niina S Tapola | 2002 | Metabolism2002，51，10： | 1 |
| 9 | On estmatiing the number of constituents of a finite mixture of continuous distribution显示文摘 | Henna J | 1985 | Ann Inst Statist Math1985，37，2： | 1 |
| 10 | The fiber and/or polyphe-nols present in lingonberries null the glycemic effect of the sugarspresent in the berries when consumed together with added glucose inhealthy human volunteers显示文摘 | Kaisa ML Riikka J Henna - Maria L | 2012 | Nutr Res2012，32，7： | 1 |
| 11 | Hormonal cryptorchidism therapy:systematic review with metanalysis of randomized clinical trials显示文摘 | Henna MR Del Nero RG Sampaio CZ | 2004 | Pediatr Surg Int2004，20，5： | 1 |
| 12 | Pyrrolidine dithiocarbamate activates Akt and improves spatial learning in APP/PS1 mice without affecting β-amyloid burden显示文摘 | Tarja MM Henna 1 Gundars G | | 0，，14： | 1 |
| 13 | Identification of some active proteins in the process of hen eggshell formation显示文摘 | A Henna' ndez-Herna' ndez J Go' mez-Morales A B Rodr' guez-Navarro | 2008 | Crystal Growth & Design2008，8，12： | 1 |
| 14 | Biobased thermosets from the free-radical copolymerization of conjugated linseed oil 显示文摘 | Phillip H Henna Dejan D Andjelkovic Petit P Kundu | 2007 | Journal of Applied Polymer Science2007，104，2： | 1 |
| 15 | Effect of ami- no acids containing sulfur on the corrosion of mild steel in phosphoric acid solutions polluted with CV, F- and Fe3+ ions-behaviour near and at the corrosion potential 显示文摘 | Morad M S S Hennas A E H A Aal M S A | 2002 | J Chem Technol Biot2002，77，4： | 1 |
| 16 | Fecal calprotectin and S100A12 have low utility in prediction of small bowel Crohn’s disease detected by wireless capsule endoscopy显示文摘 | Taina Sipponen Johanna Haapam?ki Erkki Savilahti Henrik Alfthan Esa H?m?l?inen Henna Rautiainen Jari Koskenpato Hannu Nuutinen Martti F?rkkil? | 2012 | Scandinavian Journal of Gastroenterology2012，，7： | 1 |
| 17 | Prevalence of depression,anxiety, and adjustment disorder in oncological, haematological,and palliative-care settings: a meta-analysis of 94 interview-basedstudies显示文摘 | Mitchell AJ Chan M Henna B | 2011 | Lancet Oncol2011，12，2： | 1 |
| 18 | The effects of insulin and insulin-like growth factors I and II on human ovarian follicles in long-term culture 显示文摘 | HENNA OUTI JARI | 2000 | Molecular Hum Repro2000，6，8： | 1 |
| 19 | Pyrrolidine Dithiocarbamate Activates Akt and Improves Spatial Leafing显示文摘 | Tarja Malm Henna Iivonen Gundars Goldsteins | 2007 | The Journal of Neurosciences2007，27，14： | 1 |
| 20 | Hemochromatosis gene mutations among Finnish male breast and prostate cancer patients显示文摘 | Kirsi S Henna F Tarja I | 2006 | Int J Cancer2006，118，2： | 1 |
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