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| 1 | HCV genotype distribution and possible transmission risks in Lahore, Pakistan显示文摘AIM: To investigate the prevalence of hepatitis C virus (HCV) genotypes and their association with possible transmission routes in the general population of Lahore, as the data exclusively related to this city is limited. METHODS: Complete data regarding patient's history, possible route of infection and biochemical tests was collected from the public hospital for 1364 patients. SPSS version 16 windows software was used for data analysis by univariate and multivariate techniques. RESULTS: Age range ≤ 40 years showed high prevalence of HCV infection. HCV genotype 3a was dominant (55.9%), followed by 1a (23.6%), 4a (12.5%), 3b (3.2%), untypable (2.5%), 4b (1.2%) and mixed type (1.2%). Blood transfusion, dental surgery and barber shops were the main risk factors for HCV transmission. Genotype prevalence was independent of age (P = 0.971) and gender (P = 0.122) while risk factors showed a significant association with age (P = 0.000) and genotypes (P = 0.000). We observed an independent association of risk factors and genotype 3a, while patients with genotype 1 and 4 were mostly infected due to dental surgery blood transfusion and barber shops. Risk factors of intravenous drug use and sexual exposure were exclusively found in ≤ 40 years age group. CONCLUSION: An increase in genotypes 1a and 4a suggest migration of people, possibly from Balochistan and the northern war-zone area. Government should focus on public education regarding infection routes. | Waqar Ahmad Bushra Ijaz Fouzia Tahir Javed Shah Jahan Imran Shahid Fawad Mumtaz Khan Sajida Hassan | 2010 | World Journal of Gastroenterology2010，16，34： | 2 |
| 2 | Psychological problems and family functioning as risk factors in addiction显示文摘 | Sajida A Hamid Z Syed I | 2008 | J Ayub Med Coll Abbo-ttabad2008，20，3： | 1 |
| 3 | Interaction of the hepatitis C virus (HCV) core with cellular genes in the development of HCV-induced steatosis显示文摘 | Mahwish Khan Shah Jahan Saba Khaliq Bushra Ijaz Waqar Ahmad Baila Samreen Sajida Hassan | 2010 | Archives of Virology2010，，11： | 1 |
| 4 | Stable Huh-7 cell lines expressing non-structural proteins of genotype 1a of hepatitis C virus显示文摘 | Imran Shahid Sana Gull Bushra Ijaz Waqar Ahmad Muhammad Ansar Sultan Asad Humera Kausar Muhammad Tahir Sarwar Muhammad Kazim Khan Sajida Hassan | 2013 | Journal of Virological Methods2013，，1： | 1 |
| 5 | HER‐2 expression is not prognostic in osteosarcoma; a Children’s Oncology Group prospective biology study显示文摘 | Sarah Gorlick Donald A. Barkauskas Mark Krailo Sajida Piperdi Rebecca Sowers Jonathan Gill David Geller R. Lor Randall Katherine Janeway Cindy Schwartz Holcombe Grier Paul A. Meyers Richard Gorlick Mark Bernstein Neyssa Marina | 2014 | Pediatr Blood Cancer2014，，9： | 1 |
| 6 | Experimental investigation of the thermophysical properties of Al2O3-nanofluid and its effect on a flat plate solar collector显示文摘 | Said Z Sajida M H Alima M A | 2013 | Int Commun Heat Mass Transfer2013，48，： | 1 |
| 7 | Some aspects of Fez+-catalyzed oxidation of fish sarcoplas- mic reticular lipid显示文摘 | HUANG C H HERBERT O H SAJIDA S J | 1993 | J Agric Food Chem1993，44，11： | 1 |
| 8 | Ciliotherapy: a novel intervention in polycystic kidney disease显示文摘BackgroundCiliopathies 是与主要的睫的反常结构或功能联系的一组疾病。Ciliopathies 包括 polycystic 肾疾病(PKD ) ,与脉管的高血压联系的一个病理。我们以前证明那睫长度调整睫功能,并且睫功能为氮的氧化物被要求(没有) 在 endothelial 房间的生合成。因为有 PKD 的病人显示出反常的感觉的睫功能,我们的当前的学习的目的是寻找集中于主要的睫的指向的治疗,我们叫作它 ‘ ; ciliotherapy’ ;礼品学习的 .Methods 和 ResultsIn ,我们的在里面 vitro 分析作为同等、更特定的 dopaminergic 收缩筋精制了 fenoldopam 调整睫长度和功能。我们的在里面 vivo 研究显示 fenoldopam 从而不增加了睫长度和浆液在一个 PKD 老鼠模型减少血压。我们的转线路, multicenter,双窗帘和控制安慰剂的临床的学习进一步显示那指向睫的治疗在 PKD patients.ConclusionsOverall 在吝啬的动脉的压力显示出全面减小,我们的研究在病人作为创新干预向 ciliotherapy 的第一条证据提供反常的主要的睫。 | Sarmed H. Kathem Ashraf M. Mohieldin Shakila Abdul-Majeed Sajida H. Ismail Qaiss H. Altaei Ibrahim K. Alshimmari Mohanned M. Alsaidi Hussein Khammas Andromeda M. Nauli Bina Joe Surya M. Nauli | 2014 | Journal of Geriatric Cardiology2014，11，1： | 1 |
| 9 | HCV infection causes cirrhosis in human by step-wise regulation of host genes involved in cellular functioning and defense during fibrosis:Identification of bio-markers显示文摘Chronic Hepatitis C Viral(HCV)infection is a leading health problem worldwide and resulted in fibrotic scar formation,and finally liver-cirrhosis.Although contemporary therapies can partially reverse this destructive process,the rehabilitation is too slow and unsuitable for all chronic infections.The current study elucidates the mechanism of disease progression from early(F1)to moderate(F2,F3),and to severe fibrosis(F4)/cirrhosis in HCV genotype 3a infected patients to find out new candidates as potential disease progression markers and antiviral therapeutic agents.A total of 550 genes were found differentially regulated in the four fibrosis stages and grouped in 22 classes according to their biological functions.Gene set enrichment(GSEA)and Ingenuity pathway analysis(IPA)were used to identify the regulation of crucial biological functions and pathways involved in HCV progression.HCV differentially regulated the expression of genes involved in apoptosis,cell structure,signal transduction,proliferation,metabolism,cytokine signaling,immune response,cell adhesion and maintenance,and post translational modifications by pathway analysis.There was an increasing trend of proliferative and cell growth related genes and shutting down of immune response as the disease progress mild to moderate to advanced stage cirrhosis.The myriad of changes in gene expression showed more chances of developing liver cancer in patients infected with HCV genotype 3a in a systematic manner.The identified gene set can act as disease markers for prediction,whether the fibrosis lead to cirrhosis and its association with end stage liver disease development. | Bushra Ijaz Waqar Ahmad Trina Das Khadija Shabbiri Tayyab Husnain Sajida Hassan | 2019 | Genes & Diseases2019，6，3： | 1 |
| 10 | To evaluate the role of sonography as an adjunct to mammography in women with dense breasts显示文摘 | Imrana Masroor Mohammad Nadeem Ahmed Sajida Pasha | 2009 | J Pak Med Assoc2009，59，62： | 1 |
| 11 | Review of stability measurements for frying oils and fried food flavor显示文摘 | S. L. Melton Sajida Jafar Danielle Sykes M. K. Trigiano | 1994 | Journal of the American Oil Chemists’ Society1994，，12： | 1 |
| 12 | True benefit or selection bias: an analysis of laparoscopic versus open splenectomy from the ACS-NSQIP显示文摘 | Sajida Ahad Chad Gonczy Vriti Advani Stephen Markwell Imran Hassan | 2013 | Surgical Endoscopy2013，，6： | 1 |
| 13 | Interaction of the hepatitis C virus (HCV) core with cellular genes in the development of HCV-induced steatosis显示文摘 | Mahwish Khan Shah Jahan Saba Khaliq Bushra Ijaz Waqar Ahmad Baila Samreen Sajida Hassan | 2010 | Archives of Virology2010，，11： | 1 |
| 14 | RNAi as a new therapeutic strategy against HCV显示文摘 | Saba Khaliq Sadaf A. Khaliq Muzna Zahur Bushra Ijaz Shah Jahan Muhammad Ansar Sheikh Riazuddin Sajida Hassan | 2009 | Biotechnology Advances2009，，1： | 1 |
| 15 | Efficiency of combining pomegranate juice with low-doses of cisplatin and taxotere on A549 human lung adenocarcinoma cells显示文摘Objective: To test the coalescence effect of two chemotherapy drugs at low effective dose(cisplatin and taxotere) combined with pomegranate juice on A549 cancer cells. Methods: Infrared spectroscopy method is a qualitative test that was performed to ensure the existence of the phytochemicals providing the antioxidant activity through the presence of the hydroxyl group(-OH). The viability of A549 cell line and normal MCs was tested using the neutral red uptake, Clonogenic survival, XTT and Cell migration assays. Results: Our results showed that this combination firstly led to a greater decrease in the viability of cells comparing to those treated with chemotherapy drugs alone, and secondly led to a significant reduction in cell migration. Conclusions: These data suggest a synergistic effect between the pomegranate and cisplatin which makes probably this combination a powerful option for treating lung adenocarcinoma and in parallel minimizing the systemic side effects. | Nasser Mohamad Hijazi Akram Sayed Ahmad Bouchra Jamal Eddine Zeinab Ibrahim Sajida Rammal Hassan Al Rekaby Abd-El-Ameer Nasser Mouhamad | 2018 | Asian Pacific Journal of Tropical Biomedicine2018，8，1： | 1 |
| 16 | Review of Stability Measurements for Frying Oils and Fried Food Flavor 显示文摘 | Mehonsl Sajida Danielles | 1994 | J Am Oil Chem Soc1994，71，12： | 1 |
| 17 | Role of CT in acute pancreatitis and it's complications among age groups 显示文摘 | Chisty IA Vaqar B Sajida P | 2005 | Journal of Pakistan Medical Association2005，55，10： | 1 |
| 18 | Thoracic impalement injury: A survivor with large metallic object in-situ显示文摘Impalement injuries, is a severe form of trauma, which are not common in civilian life. These injuries rarely occurs in major accidents. Abdomen, chest, limbs and perineum are often involved due to their large surface area. Thoracic impalement injury is usually a fatal injury, due to location of major vessels and heart in the thoracic cavity. These injuries are horrifying to site, but the patients who are lucky enough to make it to hospital, usually survive. Chances of survival are larger in right sided impalement injuries while central injuries are always died at the scene.Our patient, 25 years old male, was brought to the emergency room (ER) with large impaled metallic bar (about 2.5 feet long) in situ, in right sided chest. The patient was immediately shifted to operation room (OR) and was operated, his recovery was uneventful without any sequelae.Such patients should be treated and resuscitated according to advanced trauma life support (ATLS) protocols and operated without any delay for further investigations. Such operations are carried out by the most experienced surgeon team available. The impaled objects should not be processed if not necessary to avoid major hemorrhage and damage to vital structures, until the patient is in operation room. Large size and unusual position of impaled objects, makes the job difficult for surgeons/anesthetists.Although horrifying at scene, patients with thoracic impalement injuries are mostly young and healthy, and those who survive the pre-hospital phase are potentially manageable with proper resuscitation. Usually these patients make recovery without any further complications. | Randhawa Muhammad Afzal Muhammad Armughan Muhammad Waqas Javed Usman Ali Rizvi Sajida Naseem | 2018 | Chinese Journal of Traumatology2018，21，6： | 1 |
| 19 | Interaction of the hepatitis C virus (HCV) core with cellular genes in the development of HCV-induced steatosis显示文摘 | Mahwish Khan Shah Jahan Saba Khaliq Bushra Ijaz Waqar Ahmad Baila Samreen Sajida Hassan | 2010 | Archives of Virology2010，，11： | 1 |
| 20 | Multimodal Fuzzy Downstream Petroleum Supply Chain:A Novel Pentagonal Fuzzy Optimization显示文摘The petroleum industry has a complex,inflexible and challenging supply chain(SC)that impacts both the national economy as well as people’s daily lives with a range of services,including transportation,heating,electricity,lubricants,as well as chemicals and petrochemicals.In the petroleum industry,supply chain management presents several challenges,especially in the logistics sector,that are not found in other industries.In addition,logistical challenges contribute significantly to the cost of oil.Uncertainty regarding customer demand and supply significantly affects SC networks.Hence,SC flexibility can be maintained by addressing uncertainty.On the other hand,in the real world,decision-making challenges are often ambiguous or vague.In some cases,measurements are incorrect owing to measurement errors,instrument faults,etc.,which lead to a pentagonal fuzzy number(PFN)which is the extension of a fuzzy number.Therefore,it is necessary to develop quantitative models to optimize logistics operations and supply chain networks.This study proposed a linear programming model under an uncertain environment.The model minimizes the cost along the refineries,depots,multimode transport and demand nodes.Further developed pentagonal fuzzy optimization,an alternative approach is developed to solve the downstream supply chain using themixed-integer linear programming(MILP)model to obtain a feasible solution to the fuzzy transportation cost problem.In this model,the coefficient of the transportation costs and parameters is assumed to be a pentagonal fuzzy number.Furthermore,defuzzification is performed using an accuracy function.To validate the model and technique and feasibility solution,an illustrative example of the oil and gas SC is considered,providing improved results compared with existing techniques and demonstrating its ability to benefit petroleum companies is the objective of this study. | Gul Freen Sajida Kousar Nasreen Kausar Dragan Pamucar Georgia Irina Oros | 2023 | Computers, Materials & Continua2023，，3： | 0 |
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