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| 1 | Omental flaps reduces complications after pancreaticoduodenectomy显示文摘BACKGROUND:Major complications after pancreaticoduodenectomy are usually caused by a leaking pancreaticojejunal anastomosis.Omental flaps around various anastomoses were used to prevent the formation of fistula.METHODS:We reviewed 147 patients who had undergone pancreaticoduodenectomy between March 2006 and March2012.The patients were divided into 2 groups according to the application of omental flaps around various anastomoses:group A(101 patients)who underwent omental wrapping procedure;group B(46 patients)who did not undergo the omental wrapping procedure.Perioperative data of the two groups were reviewed to assess the effectiveness of omental flap procedure in the prevention of pancreatic fistula and other complications.RESULTS:No differences were observed in the clinical characteristics between the 2 groups.The incidences of pancreatic fistula(4.0%vs 17.4%),post-pancreatectomy hemorrhage(0vs 6.5%),biliary fistula(1.0%vs 13.0%),and delayed gastric emptying(4.0%vs 17.4%)were significantly less frequent in group A.The overall morbidity(18.8%vs 47.8%)and hospital stay(8.3 vs 9.6 days)were also significantly lower in group A than in group B.CONCLUSIONS:Omental flaps around various anastomoses after pancreaticoduodenectomy can reduce the incidences of pancreatic fistula,biliary fistula,post-pancreatectomy hemorrhage and delayed gastric emptying.This procedure is simple and effective to reduce the overall morbidity after pancreaticoduodenectomy. | Omar J Shah Sadaf A Bangri Manmohan Singh Reyaz A Lattoo Mohammad Y Bhat | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，3： | 19 |
| 2 | Nanotherapeutic approaches targeting angiogenesis and immune dysfunction in tumor microenvironment显示文摘Tumor microenvironment(TME) comprising cellular and non-cellular components is a major source of cancer hallmarks.Notably, angiogenesis responsible for normal physiological remodeling process can otherwise harness vessel abnormalities during tumorigenesis eliciting severe therapeutic inefficiency. Currently, FDA approved antiangiogenic drugs have only shown modest clinical success owing to tumor hypoxia, antiangiogenic therapeutic resistance, and limited knowledge in understanding TME. In order to overcome these limitations, targeting angiogenesis combined with immunosuppressive TME could offer potential therapeutic opportunities. Indeed, these therapeutic approaches can be further revisited with the advent of nanotechnology that can target the key cellular components of TME and tumor cells more precisely. Synergetic targeting without eliciting systemic toxicity achieved by integration of antiangiogenic and immunotherapy in a single nanoplatform is vital for therapeutic success. In this review, we will discuss the most promising nanotechnological advancements oriented to modulate the immunosuppressive TME in association with antiangiogenic therapy that has gained immense popularity in cancer treatment. | Sadaf Hameed Pravin Bhattarai Zhifei Dai | 2018 | Science China(Life Sciences)2018，61，4： | 7 |
| 3 | Complications and survival in patients undergoing colonic stenting for malignant obstruction显示文摘AIM:To investigate whether predicting patients that might be at a higher risk for complications might serve to improve the selection of patients undergoing colonic stenting.METHODS:A retrospective review of consecutive patients who underwent an attempted self-expandable metal stent(SEMS)insertion for malignant colonic obstruction between November 2006 and March 2013.All patients were either referred for preoperative colonic decompression with the intent of a single surgical procedure,or for palliation of the malignant colorectal obstruction for unresectable cancer.Fisher’s test orχ2test was performed on categorical variables,and the t test for continuous variables.Univariable and multivariable logistic regression were used to examine the association between independent variables and the presence of complications from SEMS insertion.RESULTS:SEMS insertion was attempted in 73 patients.Males comprised 55.71%and the mean age was 67.41±12.41 years.Of these,65.15%underwent subsequent surgery,while 34.85%received SEMS as palliation for advanced disease.Extracolonic tumors were only4.76%.The majority of patients had stageⅣdisease(63.83%),while the remainder had stageⅢ(36.17%).SEMS were successfully inserted in 93.85%(95%CI:87.85%-99.85%).Perforations occurred in 4.10%,SEMS migration in 8.21%,and stent re-occlusion from ingrowth occurred in 2.74%of patients.The mean duration of follow up for the patients was 13.52±17.48 mo(range 0-73 mo).None of the variables:age,sex,time between the onset of symptoms to SEMS insertion,time between SEMS insertion and surgery,length of the stenosis,location of the stenosis,albumin level,or receiving neoadjuvant chemotherapy,could predict the development of complications from either SEMS insertion nor prolonged survival.CONCLUSION:None of the variables could predict the development of complications or survival.Further studies are required to identify patients who would benefit the most from SEMS. | Majid A Almadi Nahla Azzam Othman Alharbi Alabbas H Mohammed Nazia Sadaf Abdulrahman M Aljebreen | 2013 | World Journal of Gastroenterology2013，19，41： | 5 |
| 4 | Pseudocayratia, a new genus of Vitaceae from China and 3apan with two new species and three new combinations显示文摘 | Jun wen Li-Min Lu Tsai-Wen Hsu Viet-Cuong Dang Sadaf Habibt John K. Boggan Hiroshi Okada I-Ju Chen Zhi-Duan Chen | 2018 | Journal of Systematics and Evolution2018，56，4： | 4 |
| 5 | Difficult-to-culture bacteria in the rhizosphere:The underexplored signature microbial groups显示文摘Microorganisms represent a substantial portion of the earth’s biodiversity and biomass, and the plant rhizosphere is an innate reservoir teeming with heterogeneous microbes predominated by bacterial communities. Rhizospheric microbial diversity (genetic, phenotypic, and metabolic) has been extensively studied to understand the key ecological roles played by the microbial members, including plant growth promotion. The application of 16S rRNA gene sequencing and next-generation sequencing (NGS) technologies has revolutionized the discovery of novel bacterial groups that have remained undetected by traditional cultivation-based approaches. Such technological advancements have opened new vistas in our current understanding of predominant but concealed and missed bacterial diversity referred to as difficult-to-culture bacterial lineages, especially the predominant phyla Acidobacteria, Verrucomicrobia,Planctomycetes, and Gemmatimonadetes. Regardless of their ubiquity and prevalence, little is known about their ecophysiology because of the non-availability of culturable members. More recently, there has been increased interest in understanding the cosmopolitan distribution and diversity of the difficult-to-culture bacteria, focusing on their role in driving complex plant-microbial interactions and mobilizing nutrients in soil and their potential as sources of novel bioactive metabolites. As an initial step, we review the distribution and significance of such bacterial phyla in soil, their ecophysiological roles, and their hidden plant growth promoting potential. The ability to select and deploy plant probiotic bacteria from the difficult-to-culture fraction of the bacterial community might open new avenues for improving crop health. | Sadaf KALAM Anirban BASU Appa Rao PODILE | 2022 | Pedosphere2022，32，1： | 4 |
| 6 | Gene-gene,gene-environment,gene-nutrient interactions and single nucleotide polymorphisms of inflammatory cytokines显示文摘Inflammation plays a significant role in the etiology of type 2 diabetes mellitus(T2DM).The rise in the pro-inflammatory cytokines is the essential step in glucotoxicity and lipotoxicity induced mitochondrial injury,oxidative stress and beta cell apoptosis in T2 DM.Among the recognized markers are interleukin(IL)-6,IL-1,IL-10,IL-18,tissue necrosis factor-alpha(TNF-α),C-reactive protein,resistin,adiponectin,tissue plasminogen activator,fibrinogen and heptoglobins.Diabetes mellitus has firm genetic and very strong environmental influence; exhibiting a polygenic mode of inheritance.Many single nucleotide polymorphisms(SNPs) in various genes including those of pro and antiinflammatory cytokines have been reported as a risk for T2 DM.Not all the SNPs have been confirmed by unifying results in different studies and wide variations have been reported in various ethnic groups.The inter-ethnic variations can be explained by the fact that gene expression may be regulated by gene-gene,gene-environment and gene-nutrient interactions.This review highlights the impact of these interactions on determining the role of single nucleotide polymorphism of IL-6,TNF-α,resistin and adiponectin in pathogenesis of T2 DM. | Amina Nadeem Sadaf Mumtaz Abdul Khaliq Naveed Muhammad Aslam Arif Siddiqui Ghulam Mustafa Lodhi Tausif Ahmad | 2015 | World Journal of Diabetes2015，6，4： | 4 |
| 7 | Should dopamine be the first line inotrope in the treatment of neonatal hypotension? Review of the evidence显示文摘AIM: To determine if dopamine is effective in treating neonatal hypotension and safe to use comparing to other inotropes. METHODS: This is a review of evidence on inotropic treatment of neonatal hypotension. Databases searched were MEDLINE and the Cochrane Library, a total of 134 studies were identified. Only studies with high quality evidence(level 1a and b and 2a) were included. After review, only eight studies were included in the final analysis. Pooled risk ratios derived for each outcome [Mantel-Haenzel(M-H) fixed effect] with CI, as reported in the Cochrane reviews were plotted in forest plot form. RESULTS: Eight articles met inclusion criteria, which all included treatment in preterm infants. Dopamine increased mean arterial blood pressure(BP)(n = 163; r = 0.88, 95%CI: 0.76 to 0.94) and systolic BP(n = 142; r = 0.81, 95%CI: 0.42 to 0.94) comparing to placebo. Dopamine has been shown overall to be statistically more effective in increasing BP than dobutamine(n = 251, r = 0.26, 95%CI: 0.20-0.32). However there were no differences in short term outcomes(periventricular leucomalacia, periventricular haemorrhage) and mortality between both drugs. There is no statistical evidence of dopamine being more effective than adrenaline or corticosteroids. There was no difference in morbidity and mortality outcomes when dopamine was compared to hydrocortisone(RR 1.81, 95%CI: 0.18 to 18.39) or adrenaline. CONCLUSION: In preterms, dopamine is the most studied drug, and we suggest it could be used as first line treatment in hypotension. | Sadaf I Bhayat Harsha MS Gowda Michael Eisenhut | 2016 | World Journal of Clinical Pediatrics2016，5，2： | 3 |
| 8 | Healing potential of cream containing extract of Sphaeranthus indicus on dermal wounds in Guinea pigs显示文摘 | Farzana Sadaf Rubeena Saleem Muhammad Ahmed Syed Iqbal Ahmad Navaid-ul-Zafar | 2006 | Journal of Ethnopharmacology2006，，2： | 3 |
| 9 | A selective approach to the surgical management of periampullary cancer patients and its outcome显示文摘BACKGROUND: Pancreaticoduodenectomy is a high risk, complex, technically challenging operation associated with significant perioperative morbidity and mortality. This study on the surgical management of periampullary cancer patients is based on our experience in a period of nearly 13 years.METHODS: The study was conducted on two groups of patients: group A included 42 patients who were treated between January 2000 and September 2005 and group B included 134 patients who were treated between October 2005 to October 2012. Preoperative, intraoperative and postoperative details of all these patients were collected, tabulated and analyzed to assess the impact of the selective approach introduced in the department with effect from October 2005.RESULTS: Intraoperative details revealed highly significant differences in the management of the two groups of patients in respect of operative time (250.4 vs 126.6 minutes; P<0.001), operative blood loss (1070.2 vs 414.9 m L; P<0.001) and intraoperative blood transfusion (1.4 vs 0.2 units; P<0.001). Variations between the two groups in the frequency of complications were found to be statistically insignificant. However, the difference between the two groups in the overall morbidity of patients (47.6% vs 26.1%; P=0.009) and the length of their hospital stay (11.8 vs 7.8 days; P<0.001) were significant.CONCLUSION: A selective approach applied to the surgical management of periampullary cancer patients is a step in the right direction. | Omar J Shah Irfan Robbani Parveen Shah Sadaf A Bangri Irfan J Khan Mohammad Y Bhat Manmohan Singh | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，6： | 3 |
| 10 | Analysis of Combined Convective and Viscous Dissipation Effects for Peristaltic Flow of Rabinowitsch Fluid Model显示文摘在这篇文章,为 Rabinowitsch 液体模型的蠕动的流动的数学建模与联合效果在一个不一致的试管被考虑粘滞驱散和对流边界条件。墙性质分析也被考虑。非维的微分方程被使用低雷纳兹数字和长波长的著名假设简化。各种各样的参数的影响与象刚硬参数 E 1, 僵硬参数 E 2, 那样的这个流动问题连接了粘滞的抑制力量参数 E 3, Brickman 数字和 Biot 数字为速度分发被阴谋,温度侧面并且为流功能。结果详细被阴谋并且讨论为砍变瘦,砍变厚并且为粘滞液体。速度侧面是刚硬参数,僵硬参数,和粘滞的抑制力量参数的增加的功能为,这被发现砍变瘦并且为粘滞液体,由于更少,抵抗由墙出现了但是,相当相反的行为被描绘为砍变厚液体。Brickman 数字联系到,这被看见粘滞驱散效果,它因此在为所有情况提高液体温度作出贡献。 | Hina Sadaf Sohail Nadeem | 2017 | Journal of Bionic Engineering2017，14，1： | 3 |
| 11 | Recent advancements in surface plasmon polaritons-plasmonics subwavelength structures in microwave and terahertz regimes显示文摘This paper presents a review of recent investigational studies on exciting Surface Plasmon Polaritous (SPPs)in MicroWave (MW)and TeraHertZ (THz)regimes by using subwavelength corrugated patterns on conductive or metal surfaces.This article also describes SPP Microstrip (MS)structures at microwave and terahertz frequencies, and compares their significance with that of conventional MS Transmission Lines (TL),in order to tackle the key challenges of high gain,bandwidth size,compactness,TL losses,and signal integrity in high-end electronic de- vices.Because they have subwavelength properties,surface plasmon polaritous are gaining attention for their improved performance and ability for miniaturization in high-speed dense circuits.They possess comparably minuscule wavelength compared to incident light (photons).Consequently,they can demonstrate stronger spatial confinement and higher local field intensity at optical frequencies.In addition to engineering spoof SPP waveguides,which are created by engraving grooves and slits on metal surfaces to allow operation on at low frequencies (microwave and terahertz),semiconductors with smaller permittivity values and thus lower free charge carrier concentration have been demonstrated as a potential candidate in plasmonic devices.If necessary,further tuning of semiconductor-based SPP structures is aided by controlling the charge carrier concentration through doping,or by external stimuli such as optical illumination or thermal excitation of charge carriers from valence to conduction bands.This article conclusively covers previously elucidated perspectives on manipulating SSPPs in the MW and THz ranges,and emphasizes how these could steer next-generation plasmonic devices. | Rana Sadaf Anwar Huansheng Ning Lingfeng Mao | 2018 | Digital Communications and Networks2018，4，4： | 3 |
| 12 | Clinical epidemiology of ulcerative colitis in Arabs based on the Montréal classification显示文摘AIM:To determine the clinical,epidemiological and phenotypic characteristics of ulcerative colitis(UC)in Saudi Arabia by studying the largest cohort of Arab UC patients.METHODS:Data from UC patients attending gastroenterology clinics in four tertiary care centers in three cities between September 2009 and September 2013were entered into a validated web-based registry,inflammatory bowel disease information system(IBDIS).The IBDIS database covers numerous aspects of inflammatory bowel disease.Patient characteristics,disease phenotype and behavior,age at diagnosis,course of the disease,and extraintestinal manifestations were recorded.RESULTS:Among 394 UC patients,males comprised51.0%and females 49.0%.According to the Montréal classification of age,the major chunk of our patients belonged to the A2 category for age of diagnosis at17-40 years(68.4%),while 24.2%belonged to the A3category for age of diagnosis at>40 years.According to the same classification,a majority of patients had extensive UC(42.7%),35.3%had left-sided colitis and29.2%had only proctitis.Moreover,51.3%were in remission,16.6%had mild UC,23.4%had moderate UC and 8.6%had severe UC.Frequent relapse occurred in17.4%patients,infrequent relapse in 77%and 4.8%had chronic disease.A majority(85.2%)of patients was steroid responsive.With regard to extraintestinal manifestations,arthritis was present in 16.4%,osteopenia in 31.4%,osteoporosis in 17.1%and cutaneous involvement in 7.0%.CONCLUSION:The majority of UC cases were young people(17-40 years),with a male preponderance.While the disease course was found to be similar to that reported in Western countries,more similarities were found with Asian countries with regards to the extent of the disease and response to steroid therapy. | Othman R Alharbi Nahla A Azzam Ahmed S Almalki Majid A Almadi Khalid A Alswat Nazia Sadaf Abdulrahman M Aljebreen | 2014 | World Journal of Gastroenterology2014，20，46： | 2 |
| 13 | Diagnostically untypable hepatitis C virus variants:It is time to resolve the problem显示文摘Pakistan is a low income country with more than 10million hepatitis C virus(HCV)infections and the burden is on continuous raise.Accurate viral genotyping is very critical for proper treatment of the infected individuals as the sustained virological response of the standard antiviral interferon therapy is genotype dependent.We observed at our diagnostic center that15.6%of HCV patient’s samples were not genotypeable by using Ohno et al method.The genotyped samples showed that 3a(68.3%)is the major prevalent genotype in Pakistan followed by 2a(10.3%),3b(2.6%),1b(1.5%),2b(1.2%)and 1a(0.5%).Presence of large number of untypable HCV variants in the current study highlights an important issue of health care setup in Pakistan.Untypable HCV cases create difficulties in treatment of these patients.The problem of routine diagnostics setup of Pakistan should be addressed on priority basis to facilitate the medical professionals in patient’s treatment and to help in achieving the maximum sustained virological response. | Muhammad Sohail Afzal Muhammad Yousaf Khan Muhammad Ammar Sadia Anjum Najm us Sahar Sadaf Zaidi | 2014 | World Journal of Gastroenterology2014，20，46： | 2 |
| 14 | Evolutionary trends in Tetrastigma (Vitaceae): Morphological diversity and taxonomic implications显示文摘Tetrastigma (Miq ) Planch。(Vitaceae ) 是有 ca 的一个类。显示出大词法差异的 100 种类。以前的分子的种系发生的研究建议传统的分类系统不与分子的发展史一致,并且 Tetrastigma 正在经历进一步系统的调查。我们在一个柔韧的种系发生的框架以内跟踪了 20 个词法人物的进化趋势。我们的结果表明然而,许多词法人物显示出多重转变或很少状态变化一些人物出现不同变化。在 Tetrastigma 的二 subgenera (subgen。Tetrastigma 和 subgen。Palmicirrata ) 基于 unbranched/bifurcate 对有指地,分叉的卷须没被支持因为 subgen。Tetrastigma 是 paraphyletic。然而, unbranched 对 bifurcate/digitately 分叉卷须具有分类用途描绘一些主要 clades。在 Tetrastigma 的开花期显得腋,但是是压缩腋的射击上的 leafopposed。我们导出 pseudoumbellate 开花期的 clade IV 发现大多数在 Tetrastigma 的种类保留了祖先的复合 dichasial 开花期,除了那些。包括习惯,叶组织,和果浆形状的另外的人物为主要 clades 提供另外的词法支持。我们的词法分析和最近的分子的学习建议每在 Tetrastigma 以内的五主要 clades 被当作不同的分类的节(在类的五节) 。 | Sadaf Habib Viet-Cuong Dang Stefanie M. Ickert-Bond Jun Wen Zhi-Duan Chen Li-Min Lu | 2018 | Journal of Systematics and Evolution2018，56，4： | 2 |
| 15 | Cooperative Sensor Anomaly Detection Using Global Information显示文摘Sensor networks are deployed in many application areas nowadays ranging from environment monitoring, industrial monitoring, and agriculture monitoring to military battlefield sensing. The accuracy of sensor readings is without a doubt one of the most important measures to evaluate the quality of a sensor and its network. Therefore, this work is motivated to propose approaches that can detect and repair erroneous (i.e., dirty) data caused by inevitable system problems involving various hardware and software components of sensor networks. As information about a single event of interest in a sensor network is usually reflected in multiple measurement points, the inconsistency among multiple sensor measurements serves as an indicator for data quality problem. The focus of this paper is thus to study methods that can effectively detect and identify erroneous data among inconsistent observations based on the inherent structure of various sensor measurement series from a group of sensors. Particularly, we present three models to characterize the inherent data structures among sensor measurement traces and then apply these models individually to guide the error detection of a sensor network. First, we propose a multivariate Gaussian model which explores the correlated data changes of a group of sensors. Second, we present a Principal Component Analysis (PCA) model which captures the sparse geometric relationship among sensors in a network. The PCA model is motivated by the fact that not all sensor networks have clustered sensor deployment and clear data correlation structure. Further, if the sensor data show non-linear characteristic, a traditional PCA model can not capture the data attributes properly. Therefore, we propose a third model which utilizes kernel functions to map the original data into a high dimensional feature space and then apply PCA model on the mapped linearized data. All these three models serve the purpose of capturing the underlying phenomenon of a sensor network from its global view, and then guide the error detection to discover any anomaly observations. We conducted simulations for each of the proposed models, and evaluated the performance by deriving the Receiver Operating Characteristic (ROC) curves. | Rui Zhang Ping Ji Dinkar Mylaraswamy Mani Srivastava Sadaf Zahedi | 2013 | Tsinghua Science and Technology2013，18，3： | 2 |
| 16 | Electromagnetic spectrum chipless radio frequency identification:A review显示文摘Over the past few years,Radio Frequency IDentification(RFID)has stridden significantly due to its adoption in many business and daily life activities.RFID empowers end-to-end and item-by-item visibility,letting the customers or decision-makers effectively trail the personnel and resources for improved management.Significant research and development in this area have transformed the inexpensive,miniaturized technology of RFIDs without chip inside.Chipless Radio Frequency IDentification(CRFID)is a unique wireless technology based on radar principle to sense,identify,and track the objects.CRFIDs are simplified and miniaturized tags of traditional RFID,which can widely be used in small and cheap objects/applications in our daily life.This paper reviews the definition,principle,and most recent development in CRFIDs.Based on the reported researches,the ElectroMagnetic Spectrum(EMS)method is typical,which has been concerned by many RFID researchers.Therefore,this paper reviews different types of EMS CRFID tag and classifies these tags based on structure design emphasizing their significant geometries in comparison with performance parameters.Antenna and coding methods of the EMS CRFID are also elaborated,contrasting the tag capacity and coding performance.Finally,we briefly summarize the challenges and limitations in this emerging field and look forward to the prospects of future CRFID. | Qingjuan Li Rana Sadaf Anwar Huansheng Ning Jun Wang Lingfeng Mao | 2020 | Digital Communications and Networks2020，6，3： | 2 |
| 17 | Effect of carbon dioxide on cerebral blood flow velocity in preterm infants during postnatal transition显示文摘 | Shahab Noori Michael Anderson Sadaf Soleymani Istvan Seri | 2014 | Acta Paediatr2014，，： | 1 |
| 18 | Performance of comput-er-aided detection applied to full-field digital mammography indetection of breast cancers显示文摘 | Sadaf A Crystal P Scaranelo A | 2011 | Eur J Radiol2011，77，： | 1 |
| 19 | Performance of sus- pended and attached growth MBR systems in treating high strength synthetic wastewater显示文摘 | Jamal K S Shazia I Sadaf J | 2011 | Bioresour Techn- ol2011，102，9： | 1 |
| 20 | Leaf-specific suppression of deoxyhypusine synthase in Arabidopsis thaliana enhances growth without negative pleiotropic effects显示文摘 | Jeremy Duguay Sadaf Jamal Zhongda Liu Tzann-Wei Wang John E. Thompson | 2006 | Journal of Plant Physiology2006，，4： | 1 |
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