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| 1 | Drug eluting biliary stents to decrease stent failure rates:Areview of the literature显示文摘Biliary stenting is clinically effective in relieving both malignant and non-malignant obstructions. However, there are high failure rates associated with tumor ingrowth and epithelial overgrowth as well as internally from biofilm development and subsequent clogging. Within the last decade, the use of prophylactic drug eluting stents as a means to reduce stent failure has been investigated. In this review we provide an overview of the current research on drug eluting biliary stents. While there is limited human trial data regarding the clinical benefit of drug eluting biliary stents in preventing stent obstruction, recent research suggests promise regarding their safety and potential efficacy. | Joseph Shatzel Jisoo Kim Kartik Sampath Sharjeel Syed Jennifer Saad Zilla H Hussain Kabir Mody J Marc Pipas Stuart Gordon Timothy Gardner Richard I Rothstein | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，2： | 6 |
| 2 | Transjugular intrahepatic porto 全身的分流在老: 为门高血压的复杂并发症的减轻显示文摘 AIM:To present a dedicated series of transjugular intrahepatic porto-systemic shunts(TIPS) in the elderly since data is sparse on this population group.METHODS:A retrospective review was performed of patients at least 65 years of age who underwent TIPS at our institutions between 1997 and 2010.Twentyfive patients were referred for TIPS.We deemed that 2 patients were not considered appropriate candidates due to their markedly advanced liver disease.Of the 23 patients suitable for TIPS,the indications for TIPS placement was portal hypertension complicated by refractory ascites alone(n = 9),hepatic hydrothorax alone(n = 2),refractory ascites and hydrothorax(n = 1),gastrointestinal bleeding alone(n = 8),gastrointestinal bleeding and ascites(n = 3).RESULTS:Of these 23 attempted TIPS procedure patients,21 patients had technically successful TIPS procedures.A total of 29 out of 32 TIPS procedures including revisions were successful in 21 patients with a mean age of 72.1 years(range 65-82 years).Three of the procedures were unsuccessful attempts at TIPS and 8 procedures were successful revisions of our existing TIPS.Sixteen of 21 patients who underwent successful TIPS(excluding 5 patients lost to follow-up) were followed for a mean of 14.7 mo.Ascites and/or hydrothorax was controlled following technically successful procedures in 12 of 13 patients.Bleeding was controlled following technically successful procedures in 10 out of 11 patients.CONCLUSION:We have demonstrated that TIPS is an effective procedure to control refractory complications of portal hypertension in elderly patients. | Mubin I Syed Hetal Karsan Hector Ferral Azim Shaikh Uzma Waheed Talal Akhter Alan Gabbard Kamal Morar Robert Tyrrell | 2012 | World Journal of Hepatology2012，4，2： | 4 |
| 3 | Impact and risk factors of post-stroke bone fracture显示文摘Bone fracture occurs in stroke patients at different times during the recovery phase, prolonging recovery time and increasing medical costs. In this review, we discuss the potential risk factors for post-stroke bone fracture and preventive methods. Most post-stroke bone fractures occur in the lower extremities, indicating fragile bones are a risk factor. Motor changes, including posture, mobility, and balance post-stroke contribute to bone loss and thus increase risk of bone fracture. Bone mineral density is a useful indicator for bone resorption, useful to identify patients at risk of post-stroke bone fracture. Calcium supplementation was previously regarded as a useful treatment during physical rehabilitation. However, recent data suggests calcium supplementation has a negative impact on atherosclerotic conditions. Vitamin D intake may prevent osteoporosis and fractures in patients with stroke. Although drugs such as teriparatide show some benefits in preventing osteoporosis, additional clinical trials are needed to determine the most effective conditions for post-stroke applications. | Kang Huo Syed I Hashim Kimberley LY Yong Hua Su Qiu-Min Qu | 2016 | World Journal of Experimental Medicine2016，6，1： | 2 |
| 4 | Concordance between functional magnetic resonance imaging and introperative language mapping显示文摘 | MAXIMILIAN I R JONATHAN D V SYED H | 1999 | Stereotact Funct Neurosurg1999，72，4： | 1 |
| 5 | Tz-weighted MR ima-ging in the assessment of cirrhotic liver显示文摘 | Hussain HK Syed I Nghiem HV | 2004 | Radiology2004，230，： | 1 |
| 6 | Correl atation (TID) male patient ion and 显示文摘 | Aldhilan between coronary A Syed GM transient i Suleiman I schemic dil artery disease in Saudi | 2014 | J Saudi Heart hssoc2014，26，1： | 1 |
| 7 | Angiotensin II type U recep-tor deficiency accelerates the development of nephropathy in type idiabetes via oxidative stress and ACE2 显示文摘 | Chang SY Chen YW Chenier I | 2011 | Exp Diabetes Res2011，，52： | 1 |
| 8 | The complete nucleotide sequence and gene organization of the mitochondrial genome of the bumblebee,Bombus ignitus (Hymenoptera:Apidae)显示文摘 | Cha SY Yoon HJ Lee EM Yoon MH Hwang JS Jin BR Han YS Kim I | | 0，，1： | 1 |
| 9 | Correlation of aging and smoking with air trapping at thin - section CT of the lung in asymptomatic subjects 显示文摘 | Lee KW Chung SY Yang I | 2000 | Radiology2000，214，3： | 1 |
| 10 | 锐钛型钛二氧化物纳米颗粒对小鼠的影响:证据表明短时间而不是长时间的暴露会导致小鼠精子结构和功能的异常显示文摘锐钛型钛二氧化物纳米颗粒(TNPs)广泛应用在商业领域,并且存在于不同的产品中。为明确更小剂量的锐钛型钛二氧化物纳米颗粒(ATNPs)间隔一定距离进入体内到达阴囊后是否能诱导精子缺陷的发生,雄性成年小鼠持续3天腹腔内注射100%ATNP(2.5或5mg/kg),然后在注射后1周、2周、3周或5周(长时间暴露)或者是注射后24小时、48小时或120小时(短时间暴露)处死。透射电镜表明在注射后120小时收集到的阴囊脂肪组织中,附睾组织和附睾液均出现炎症反应。在注射后120小时和3周后,睾丸组织间质间隙增大。利用末端脱氧核糖核酸转移酶介导的缺口末端标记技术发现在注射后的雄鼠体内阳性(即凋亡)精子(P=0.002)和间质细胞(P=O.04)数目均显著增加。与对照组相比,短时间暴露而不是长时间暴露的附睾尾部精子鞭毛异常、过量胞浆残余(ERC)的发生率增加,精子无顶体反应的发生率增加(呈剂量依赖性)。ERC与无顶体反应是否存在相关性目前尚不清楚。与对照组相比,暴露120小时组快速运动精子数量和线粒体膜电位均显著下降(P〈0.05),同时,活性氧水平显著增加(P〈0.00001)。这些结果表明在注射后4.8天,ANTP能够引发不育的精子结构和功能的异常,并且通过氧化应激造成DNA的损伤。同时,在暴露后的10天到5周末检测到精子的异常,这表明精子的这种异常是暂时性的。 | Michelle A Smith Rowan Michael Rolands G Aravindan Soma Dash Syed I Shah Deni S Galileo Patricia A Martin-DeLeon | 2015 | Asian Journal of Andrology2015，17，2： | 1 |
| 11 | A randomized phase II trial of' S-I- cxaliplatin versus capeciiabine-oxaliplatin in adwmced gaslric cancev显示文摘 | Kim GM Jeung El(i Rha SY el aI | 2012 | EurJ Can rer2012，48，4： | 1 |
| 12 | Treatment of oily water using hydrophobic nano-silica 显示文摘 | Syed S Alhazzaa M I Asif M | 2011 | Chemical Engineering Journal2011，167，1： | 1 |
| 13 | Laparoscopic versus poen repair of incisional/ventral hernia:a meta-analysis显示文摘 | Muhammad SS Syed A Bokhari I | 2009 | Am J Surg2009，197，1： | 1 |
| 14 | Psychological problems and family functioning as risk factors in addiction显示文摘 | Sajida A Hamid Z Syed I | 2008 | J Ayub Med Coll Abbo-ttabad2008，20，3： | 1 |
| 15 | T2-weighted MR imaging in the assessment of cirrhotic liver显示文摘 | Hussain HK Syed I Nghiem HV | 2004 | Radiology2004，230，3： | 1 |
| 16 | Predilection of the macular region to high incidence of choroidal neovascularization after intense laser photocoagulation in the monkey显示文摘 | Shen WY Lee SY Yeo I | 2004 | Arch Ophthalmol2004，122，： | 1 |
| 17 | Different genetic effect of PXK on systemic lupuseryth ematosus in the Korean population 显示文摘 | Kim EM Bang SY Kim I | 2012 | Rheumatol Int2012，32，1： | 1 |
| 18 | Immune suppression in cynomolgus monkeys by XPro9523:an improved CTLA4-Ig fusion w ith enhanced binding to CD80,CD86 and neonatal Fc receptor FcRn显示文摘 | Bernett MJ Chu SY Leung I | 2013 | M Abs2013，5，3： | 1 |
| 19 | A study to explore nurses' knowledge in using the Glasgow Coma Scale in an acute care hospital显示文摘 | Mattar I Liaw SY Chan MF | 2013 | J Neurosci Nurs2013，45，5： | 1 |
| 20 | Distinct effects of two CD44 isoforms on tumor growth in vivo显示文摘 | Guo YJ Stamenkovic I | 1991 | Exp Med1991，174，4： | 1 |
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