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| 1 | Perioperative blood transfusion decreases long-term survival in pediatric living donor liver transplantation显示文摘BACKGROUND The impact of perioperative blood transfusion on short-and long-term outcomes in pediatric living donor liver transplantation(PLDLT)must still be ascertained,mainly among young children.Clinical and surgical postoperative complications related to perioperative blood transfusion are well described up to three months after adult liver transplantation.AIM To determine whether transfusion is associated with early and late postoperative complications and mortality in small patients undergoing PLDLT.METHODS We evaluated the effects of perioperative transfusion on postoperative complications in recipients up to 20 kg of body weight,submitted to PLDLT.A total of 240 patients were retrospectively allocated into two groups according to postoperative complications:Minor complications(n=109)and major complications(n=131).Multiple logistic regression analysis identified the volume of perioperative packed red blood cells(RBC)transfusion as the only independent risk factor for major postoperative complications.The receiver operating characteristic curve was drawn to identify the optimal volume of the perioperative RBC transfusion related to the presence of major postoperative complications,defining a cutoff point of 27.5 mL/kg.Subsequently,patients were reallocated to a low-volume transfusion group(LTr;n=103,RBC≤27.5 mL/kg)and a high-volume transfusion group(HTr;n=137,RBC>27.5 mL/kg)so that the outcome could be analyzed.RESULTS High-volume transfusion was associated with an increased number of major complications and mortality during hospitalization up to a 10-year follow-up period.During a short-term period,the HTr showed an increase in major infectious,cardiovascular,respiratory,and bleeding complications,with a decrease in rejection complications compared to the LTr.Over a long-term period,the HTr showed an increase in major infectious,cardiovascular,respiratory,and minor neoplastic complications,with a decrease in rejection complications.Additionally,Cox hazard regression found that high-volume RBC transfusion increased the mortality risk by 3.031-fold compared to low-volume transfusion.The Kaplan-Meier survival curves of the studied groups were compared using log-rank tests and the analysis showed significantly decreased graft survival,but with no impact in patient survival related to major complications.On the other hand,there was a significant decrease in both graft and patient survival,with high-volume RBC transfusion.CONCLUSION Transfusion of RBC volume higher than 27.5 mL/kg during the perioperative period is associated with a significant increase in short-and long-term postoperative morbidity and mortality after PLDLT. | Karina Gordon Estela Regina Ramos Figueira Joel Avancini Rocha-Filho Luiz Antonio Mondadori Eduardo Henrique Giroud Joaquim Joao Seda-Neto Eduardo Antunes da Fonseca Renata Pereira Sustovitch Pugliese Agustin Moscoso Vintimilla Jose Otavio Costa Auler Jr Maria Jose Carvalho Carmona Luiz Augusto Carneiro D'Alburquerque | 2021 | World Journal of Gastroenterology2021，27，12： | 6 |
| 2 | Tribological performance of tributylmethylammonium bis(trifluoromethylsulfonyl)amide as neat lubricant and as an additive in a polar oil显示文摘The ionic liquid(IL) tributylmethylammonium bis(trifluoromethylsulfonyl)amide([N4441][NTf2]) was used as neat lubricant and as an additive(1.5 wt%) in a polar oil to study its friction and wear reducing properties.Tribological tests were completed for 90 minutes at room temperature and 100 °C in a reciprocating configuration at loads of 30 and 70 N,10 Hz-frequency,and 4 mm stroke length.Wear volume was measured by confocal microscopy and the surface-IL interaction determined by XPS.The main findings were that neat IL showed the best tribological behavior;the IL-containing mixture behaved similar to the base oil regarding friction,however outperformed the antiwear behavior of the base oil under higher temperature;surface-IL chemical interaction was found mainly at 100 °C. | Rubén GONZáLEZ Diego RAMOS David BLANCO Alfonso FERNáNDEZ-GONZáLEZ Jose L.VIESCA Mark HADFIELD Antolin HERNáNDEZ BATTEZ | 2019 | Friction2019，7，3： | 3 |
| 3 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 4 | Gastric partitioning for the treatment of malignant gastric outlet obstruction显示文摘BACKGROUND Gastric outlet obstruction(GOO)is one of the main complications in stage IV gastric cancer patients.This condition is usually managed by gastrojejunostomy(GJ).However,gastric partitioning(GP)has been described as an alternative to overcoming possible drawbacks of GJ,such as delayed gastric emptying and tumor bleeding.AIM To compare the outcomes of patients who underwent GP and GJ for malignant GOO.METHODS We retrospectively analyzed 60 patients who underwent palliative gastric bypass for unresectable distal gastric cancer with GOO from 2009 to 2018.Baseline clinicopathological characteristics including age,nutritional status,body mass index,and performance status were evaluated.Obstructive symptoms were graded according to GOO score(GOOS).Surgical outcomes evaluated included duration of the procedure,surgical complications,mortality,and length of hospital stay.Acceptance of oral diet after the procedure,weight gain,and overall survival were the long-term outcomes evaluated.RESULTS GP was performed in 30 patients and conventional GJ in the other 30 patients.The mean follow-up was 9.2 mo.Forty-nine(81.6%)patients died during that period.All variables were similar between groups,with the exception of worse performance status in GP patients.The mean operative time was higher in the GP group(161.2 vs 85.2 min,P<0.001).There were no differences in postoperative complications and surgical mortality between groups.The median overall survival was 7 and 8.4 mo for the GP and GJ groups,respectively(P=0.610).The oral acceptance of soft solids(GOOS 2)and low residue or full diet(GOOS 3)were reached by 28(93.3%)GP patients and 22(75.9%)GJ patients(P=0.080).Multivariate analysis demonstrated that GOOS 2 and GOOS 3 were the main prognostic factors for survival(hazard ratio:8.90,95%confidence interval:3.38-23.43,P<0.001).CONCLUSION GP is a safe and effective procedure to treat GOO.Compared to GJ,it provides similar surgical outcomes with a trend to better solid diet acceptance by patients. | Marcus Fernando Kodama Pertille Ramos Leandro Cardoso Barchi Rodrigo Jose de Oliveira Marina Alessandra Pereira Donato Roberto Mucerino Ulysses Ribeiro Jr Bruno Zilberstein Ivan Cecconello | 2019 | World Journal of Gastrointestinal Oncology2019，11，12： | 2 |
| 5 | FPGA adaptive optics system test bench 显示文摘 | Rodriguez Ramos L F Viera Teodora Gigante Jose V | 2005 | SPIE2005，5903，： | 1 |
| 6 | Expression of COX-2 on Reed-Sternberg cells is an independent unfavorable prognostic factor in Hodgkin lymphoma treated with ABVD显示文摘 | Francisco Mestre Antonio Gutierrez Rafael Ramos Jordi Martinez-Serra Lydia Sánchez Gabriel Matheu Teresa Ros Juan Fernando Garcia Jose Rodriguez | 2012 | Blood2012，，25： | 1 |
| 7 | Randomized trial of non-invasive ventilation combined with exercise training in patients with chronic hypercapnic failure due to Chronic Obstructive Pulmonary Disease显示文摘 | Eduardo Márquez-Martín Francisco Ortega Ruiz Pilar Cejudo Ramos Jose Luis López-Campos Borja Valencia Azcona Emilia Barrot Cortés | 2014 | Respiratory Medicine2014，，： | 1 |
| 8 | Inspiratory Muscle Training in Patients With COPD显示文摘 | Hildegard Sánchez Riera Teodoro Montemayor Rubio Francisco Ortega Ruiz Pilar Cejudo Ramos Daniel Del Castillo Otero Teresa Elias Hernandez Jose Castillo Gomez | 2001 | Chest2001，，3： | 1 |
| 9 | Bioactive components of ovine and caprine cheese whey显示文摘 | BLANCA HERNANDEZ LEDESMA MERCEDES RAMOS JOSE ANGEL GOMEZ-RUIZ | 2011 | Small Ruminant Research2011，，101： | 1 |
| 10 | Microstructure evaluation and mechanical properties of a friction stir spot welded TRIP 800 steel 显示文摘 | Cintia Cristiane Petty Mazzaferro Fabiano Domelles Ramos Jose Antonio Esmerio Mazzaferro | 2011 | Welding International2011，25，9： | 1 |
| 11 | 'Changes in the Intellectual Structure of Strategic Management Research: A Bibliometric Study of the Strategic Management Journal: 1980- 2000显示文摘 | Antonio - Rafael Ramos - Rodriguez and Jose Ruiz -Navarro | 2004 | Strategic Management Journal2004，，25： | 1 |
| 12 | Identification and formation of angiotensin-converting enzyme-inhibitory peptides in Manchego cheese by high-performance liquid chromatography tandem mass spectrometry 显示文摘 | Jose angel Gomez-Ruiz Mercedes Ramos Isidra Recio | 2004 | Journal of Chromatography A2004，1054，： | 1 |
| 13 | Effcient equali- zation of multi exciter distributed mode loudspeakers显示文摘 | Basilio Pueo Jose J L6pez German Ramos | 2009 | Applied Acoustics2009，，20： | 1 |
| 14 | Organizational learning capability: a proposal of measurement 显示文摘 | Pilar J G Jose C L Ramo V C | 2005 | Journal of Business Research2005，58，6： | 1 |
| 15 | Apopotosis induction in Jurkat cell and sCD95 levels in wonents sera are related with the risk of developing cervical cancer显示文摘 | Adriana A L Jose E Romero - Ramos Vicent O A | 2008 | BMC Cancer2008，8，： | 1 |
| 16 | Semicontinuous Seeded Cationic Emulsion Polymerization of Styrene: The Effects of the Concentration and Type of Cationic Surfactant 显示文摘 | Jose Ramos Jacqueline Forcada | 2003 | Journal of Polymer Science:Part A: Polymer Chemistry2003，，41： | 1 |
| 17 | Cow’s milk allergy: color Doppler ultrasound findings in infants with hematochezia显示文摘 | Matias Epifanio Jose Vicente Spolidoro Nathalia Guarienti Missima Ricardo Bernardi Soder Pedro Celiny Ramos Garcia Matteo Baldisserotto | 2013 | Jornal de Pediatria (Versao en Portugues)2013，，： | 1 |
| 18 | Linkage of a geographical information system with the gleams model to access nitrate leaching in agricultural areas显示文摘 | Jose Miguel de Paz Carlos Ramos | 2002 | Environmental Pollution2002，118，： | 1 |
| 19 | Organizational learning capability: a proposal of measurement 显示文摘 | PILAR JEREZ - GO' MEZ JOSE' CE' SPEDES - LORENTEA RAMO'N VAIX E - CABRERAB | 2005 | Journal of Business Research2005，58，： | 1 |
| 20 | Production of magnetic nanoparticles in imine polymer matrixes显示文摘 | Cristina Castro Jose Ramos Angel Millan | 2000 | Chem Mater2000，12，： | 1 |
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