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| 1 | 成人缺血性卒中早期处理指南显示文摘本指南旨在对成年急性缺血性卒中患者评价和治疗各要素的现有证据做一回顾。目标读者是那些为发病后48h内的卒中患者提供治疗的内科医生和其他急诊医疗保健人员。另外,也包括向医疗保健政策制定者提供的信息。方法:专家小组成员由美国心脏协会(AHA)卒中委员会科学声明监督委员会任命,他们代表了来自不同领域的专家。专家小组以2003年后发表的报道为重点,对相关文献进行回顾,采用AHA卒中委员会的证据水平分级标准对证据进行分级并做出推荐。本声明经专家小组认可后,再由AHA科学顾问和协调委员会进行同行评议和正式批准。本指南打算在3年内做全面更新。结果:对急性缺血性卒中患者的处理仍然是多方面的,包括尚未在临床试验中进行过验证的一些医疗诊治方面。本声明包括从急诊医疗服务人员开始接触患者到入院初期处理的推荐意见。静脉重组组织型纤溶酶原激活剂仍然是已得到证实的最有效的卒中急诊治疗干预方法。包括动脉应用溶栓药和机械介入在内的一些方法显示出希望。因为许多推荐是在有限的证据基础上做出的,因此需要对急性缺血性卒中的治疗进行更多的研究。 | Harold P. Adams Gregory del Zoppo Mark J. Alberts Deepak L. Bhatt Lawrence Brass Anthony Furlan Robert L. Grubb Randall T. Higashida Edward C. Jauch Chelsea Kidwell Patrick D. Lyden Lewis B. Morgenstern Adnan I. Qureshi Robert H. Rosenwasser Phillip A. Scott Eelco F.M. Wijdicks 李焰生(译) 熊昕丽(译) 林岩(译) 沈沸(译) 俞羚(译) 邹静(译) 张静芳(译) 孙亚蒙(译) 周洁茹(译) 蒋仙国(译) 陈莺(译) | 2007 | 国际脑血管病杂志2007，15，6： | 18 |
| 2 | Clinical Deterioration Following Improvement in the NINDS rt-PA Stroke Trial显示文摘 | James C. Grotta K.M.A. Welch Susan C. Fagan Mei Lu Michael R. Frankel Thomas Brott Steven R. Levine Patrick D. Lyden | 2001 | Stroke: Journal of the American Heart Association2001，，3： | 2 |
| 3 | Type of admission is associated with outcome of spontaneous subarachnoid hemorrhage显示文摘 | Doniel Drazin Jack Rosner Miriam Nu?o Michael J. Alexander Wouter I. Schievink David Palestrant Patrick D. Lyden Chad Miller | 2015 | Int J Stroke2015，，： | 1 |
| 4 | A critical appraisal of stroke evaluation and rating soales显示文摘 | Patrick D Lyden MD Grabriel T | 1991 | Stroke1991，22，： | 1 |
| 5 | Development of the Italian Version of the National Institutes of Health Stroke Scale: It-NIHSS显示文摘 | Francesca Romana Pezzella Orietta Picconi Assunta De Luca Patrick D. Lyden Marco Fiorelli | 2009 | Stroke2009，，7： | 1 |
| 6 | Endovascular management of iliac artery occlusions: extending treatment to TransAtlantic Inter-Society Consensus class C and D patients显示文摘 | Christopher D. Leville Vikram S. Kashyap Daniel G. Clair James F. Bena Sean P. Lyden Roy K. Greenberg Patrick J. O’Hara Timur P. Sarac Kenneth Ouriel | 2006 | Journal of Vascular Surgery2006，，1： | 1 |
| 7 | A Modified National Institutes of Health Stroke Scale for Use in Stroke Clinical Trials: Preliminary Reliability and Validity显示文摘 | Patrick D. Lyden Mei Lu Steven R. Levine Thomas G. Brott Joseph Broderick | 2001 | Stroke: Journal of the American Heart Association2001，，6： | 1 |
| 8 | Revisiting cerebral postischemic reperfusion injury: new insights in understanding reperfusion failure, hemorrhage, and edema显示文摘 | Jilin Bai Patrick D. Lyden | 2015 | Int J Stroke2015，，2： | 1 |
| 9 | Neuroprotectsnt in the treatment of stroke-An overview显示文摘 | Ntis Gunnar Wahigren Patrick Lyden | 2000 | J Stroke Cerobrovasc Dis2000，9，： | 1 |
| 10 | Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials显示文摘 | Jonathan Emberson Kennedy R Lees Patrick Lyden Lisa Blackwell Gregory Albers Erich Bluhmki Thomas Brott Geoff Cohen Stephen Davis Geoffrey Donnan James Grotta George Howard Markku Kaste Masatoshi Koga Ruediger von Kummer Maarten Lansberg Richard I Lindley | 2014 | The Lancet . 2014 (9958)2014，，： | 1 |
| 11 | A critical Appraisal of Stroke evaluation and rating scales显示文摘 | Patrick D Lyden MD Gabriel T | 1991 | Stroke1991，22，： | 1 |
| 12 | A critical appraisel of stroke evaluation and rating scales显示文摘 | Patrick D Lyden MD Grabriel T | 1991 | Stroke1991，22，： | 1 |
| 13 | Protective effect of synaptic inhibition during cerebral ischemia in rats and rabbits显示文摘 | Patrick D Lyden MD Brenda Hecges BS | 1992 | Stroke1992，23，： | 1 |
| 14 | Analysis of the National Institute of Neurological Disorders and Stroke Tissue Plasminogen Activator Studies Following European Cooperative Acute Stroke Study III Patient Selection Criteria显示文摘 | Thomas M. Hemmen Karen S. Rapp Jennifer A. Emond Rema Raman Patrick D. Lyden | 2010 | Journal of Stroke and Cerebrovascular Diseases2010，，4： | 1 |
| 15 | Endovascular repair of abdominal aortic aneurysms: Device-specific outcome显示文摘 | Kenneth Ouriel Daniel G. Clair Roy K. Greenberg Sean P. Lyden Patrick J. O’Hara Timur P. Sarac Sunita D. Srivastava Brett Butler Ellis S.K. Sampram | 2003 | Journal of Vascular Surgery2003，，： | 1 |
| 16 | Serum Calcium as Prognosticator in Ischemic Stroke显示文摘 | Bruce Ovbiagele Sidney Starkman Philip Teal Patrick Lyden Markku Kaste Stephen M. Davis Werner Hacke Monika Fierus Jeffrey L. Saver | 2008 | Stroke2008，，： | 1 |
| 17 | Hematoma Growth in Oral Anticoagulant Related Intracerebral Hemorrhage显示文摘 | Brett Cucchiara Steven Messe Lauren Sansing Scott Kasner Patrick Lyden | 2008 | Stroke2008，，11： | 1 |
| 18 | Evolution of the treatment window for acute ischemic stroke 显示文摘 | Andrew Stemer Patrick Lyden | 2010 | Curr Neurol Neurosci Rep2010，10，： | 1 |
| 19 | Acute Vascular Disruption and Aquaporin 4 Loss After Stroke显示文摘 | Beth Friedman Christian Schachtrup Philbert S. Tsai Andy Y. Shih Katerina Akassoglou David Kleinfeld Patrick D. Lyden | 2009 | Stroke2009，，6： | 1 |
| 20 | 溶栓治疗急性脑卒中刻不容缓显示文摘ECASSⅢ研究结果公布之后最令人担心的,可能会促使某些医生延迟治疗急性脑卒中的时间,如果这样则大错特错。 | Patrick Lyden Creaty(编译) | 2008 | 中国处方药2008，，9： | 0 |
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