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| 1 | Potential of phloroglucinol to improve erectile dysfunction associated with streptozotocin-induced diabetes in rats显示文摘Objective: Diabetes is a common metabolic disease with several complications in its patients. Often, people living with diabetes develop erectile dysfunction (ED). The primary aim of this work was to investigate the effect of phloroglucinol in diabetes-induced ED in rats. Methods: Male Wistar rats were given 52 mg/kg of streptozotocin, by intraperitoneal injection, to induce diabetes and ED. Subsequently, animals were grouped into three groups: group 1, diabetic control;group 2, low-dose phloroglucinol (150 mg/kg body weight);and group 3, high-dose phloroglucinol (250 mg/kg body weight). A group of six normal rats served as a normal control. The rats were treated with phloroglucinol for six weeks and then were assessed for treatment effects. Sexual behavior, glycosylated hemoglobin Ale (HbAlc) values, serum testosterone, serum nitric oxide (NO), blood pressure and sperm count were measured after the end of treatment. Results: After a 6-week treatment period, the high dose of phloroglucinol significantly decreased HbAlc values in diabetic rats. Rats treated with phloroglucinol had increased serum testosterone, NO and sperm count. Animals treated with 250 mg/kg phloroglucinol performed similar to normal rats in the sexual behavioral study, suggesting the reversal of complications of ED. Conversely, a decrease in the blood pressure in treated groups was observed. Conclusion: The results highlight the protective effect of phloroglucinol in diabetes-induced ED in rats warranting further studies. | Syed Kashif Rema Razdan Ramanaiah Illuri | 2019 | Journal of Integrative Medicine2019，17，4： | 3 |
| 2 | Activity-dependent plasticity in adult somatic sensory cortex显示文摘 | EBNER F F REMA V SACHDEV R SYMONS F J | 1997 | Seminars in Neuroscience1997，，9： | 1 |
| 3 | Oxidative DNA damage and augmentation of poly (ADP-ribose) polymerase/nuclear factor-kappa B signaling in patients with type 2 diabetes and microangiopathy 显示文摘 | Adaikalakoteswari A Rema M Mohan V | 2007 | Int J Biochem Cell Biol2007，39，9： | 1 |
| 4 | Prevalence of diabetic retinopathy in urban India: the Chennai Urban Rural Epidemiology Study (CURES) eye study, I 显示文摘 | Rema M Premkumar S Anitha B | 2005 | Invest Ophthalmol Vis Sci2005，46，7： | 1 |
| 5 | Instrumental assess- ments of Japanese white salted noodle quality显示文摘 | Yun S H Rema G Quail K | 1997 | J Sci Food Agric1997，74，： | 1 |
| 6 | Instrumental assessments ofJapanese white salted noodle quality 显示文摘 | Yun S H Rema G Quail K | 1997 | J Sci Food Agric1997，74，： | 1 |
| 7 | Intravenous thrombolysis plus hypothermia for acute treatment of ischemic stroke (ICTuS-L):final results显示文摘 | Thomas MH Rema R Kama ZG | 2010 | Stroke2010，41，10： | 1 |
| 8 | Differential gene expression of NADPH oxidase (p22phox) and hemoxygenase-1 in patients with Type 2 diabetes and microangiopathy 显示文摘 | Adaikalakoteswari A Balasubramanyam M Rema M | 2006 | Diabet Med2006，23，6： | 1 |
| 9 | Effectiveness and safety of loop electrosurgical excision procedure in a low-resource setting 显示文摘 | Rema P Suchetha S Thara S | 2008 | Int J Gynaecol Obstet2008，103，2： | 1 |
| 10 | Prevalence of diabetic retinopathy in urban India: the chennai urban rural epidemiology study (CURES) eye study, I显示文摘 | Rema M Premkumar S Anitha B | 2005 | Invest Ophthalmol Vis Sci2005，46，7： | 1 |
| 11 | Genes and diabetic retinopathy 显示文摘 | Radha V Rema M Mohan V | 2002 | Indian J Ophthalmol2002，50，1： | 1 |
| 12 | Effect of curcumin on proliferation of human retinal endothelial cells under in vitro conditions显示文摘 | Premanand C Rema M Sameer MZ | | 0，，： | 1 |
| 13 | Prevalence of diabetic retinopathy in urban India:The Chennai Urban Rural Epidemiology Study (CURES) Eye Study,I显示文摘 | Rema M Premkumar S Anitha B | 2005 | Invest Ophthalmol Vis Sci2005，46，： | 1 |
| 14 | Colouring ornamental fish(Cyprinus carpio and Carassius auratus)with microalgal biomass显示文摘 | Gouveia L Rema P Pereira O | 2003 | Aquacult Nutr2003，9，2： | 1 |
| 15 | 2003, Micropropagation of cam- phor tree (Cinnamomum camphora)显示文摘 | Babu K N Sajina A Minoo D John C Z Mini P M Tushar K V Rema J Ravindran P N | 2003 | Plant Cell Tissue and Organ Cuhure2003，74，2： | 1 |
| 16 | Prevalence and risk factors for diabetic neuropathy in an urban south Indian population:the Chennai Urban Rural Epidemiology Study( CURES-55 ) 显示文摘 | Pradeepa R Rema M Vignesh J Deepa M Deepa R Mohan Y | 2008 | Diabet Med2008，25，4： | 1 |
| 17 | Secondary cytoreduc- tion in epithelial ovarian cancer recurrence:a perspective from a regional cancer center in India显示文摘 | Rema PN Suchetha S Mathew AP | 2009 | J Reprod Med2009，54，8： | 1 |
| 18 | Oxidative DNA damage and augmentation of poly (ADP-ribose)polymerase /nuclear factor-kappa B signaling in patients with type 2 diabetes and microangiopathy显示文摘 | Adaikalakoteswari A Rema M Mohan V | | 0，，09： | 1 |
| 19 | Prevalence of microalbuminuria in type 2 diabetes mellitus at a diabetes centre in southen India 显示文摘 | Varghese A Deepa R Rema M et a1 | 2001 | Postgrad Med2001，77，8： | 1 |
| 20 | Expansion of immuno stimulato rydendritic cells among the myeloid p rogeny of human CD34+ bonemarrow precursors cultured with ckit ligand,GM-CSF and TNFα显示文摘 | Szabo lcs P Moo reMA S Young JW | 1995 | J Immuno l1995，154，49： | 1 |
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