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| 1 | Mitochondrial PKM2 regulates oxidative stress-induced apoptosis by stabilizing Bcl2显示文摘 | Ji Liang Ruixiu Cao Xiongjun Wang Yajuan Zhang Pan Wang Hong Gao Chen Li Fan Yang Rong Zeng Ping Wei Dawei Li Wenfeng Li Weiwei Yang | 2017 | Cell Research2017，27，3： | 39 |
| 2 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 3 | Ultrasensitive skin‐like wearable optical sensors based on glass micro/nanofibers显示文摘Electronic skin,a class of wearable electronic sensors that mimic the functionalities of human skin,has made remarkable success in applications including health monitoring,human-machine interaction and electronic-biological interfaces.While electronic skin continues to achieve higher sensitivity and faster response,its ultimate performance is fundamentally limited by the nature of low-frequency AC currents.Herein,highly sensitive skin-like wearable optical sensors are demonstrated by embedding glass micro/nanofibers(MNFs)in thin layers of polydimethylsiloxane(PDMS).Enabled by the transition from guided modes into radiation modes of the waveguiding MNFs upon external stimuli,the skin-like optical sensors show ultrahigh sensitivity(1870 k·Pa^-1),low detection limit(7 mPa)and fast response(10μs)for pressure sensing,significantly exceeding the performance metrics of state-of-the-art electronic skins.Electromagnetic interference(EMI)-free detection of high-frequency vibrations,wrist pulse and human voice are realized.Moreover,a five-sensor optical data glove and a 2×2-MNF tactile sensor are demonstrated.These initial results pave the way toward a new category of optical devices ranging from ultrasensitive wearable sensors to optical skins. | Lei Zhang Jing Pan Zhang Zhang Hao Wu Ni Yao Dawei Cai Yingxin Xu Jin Zhang Guofei Sun Liqiang Wang Weidong Geng Wenguang Jin Wei Fang Dawei Di Limin Tong | 2020 | Opto-Electronic Advances2020，3，3： | 12 |
| 4 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 5 | Chemical formation and source apportionment of PM_(2.5) at an urban site at the southern foot of the Taihang mountains显示文摘The region along the Taihang Mountains in the North China Plain(NCP) is characterized by serious fine particle pollution. To clarify the formation mechanism and controlling factors, an observational study was conducted to investigate the physical and chemical properties of the fine particulate matter in Jiaozuo city, China. Mass concentrations of the water-soluble ions(WSIs) in PM_(2.5) and gaseous pollutant precursors were measured on an hourly basis from December 1, 2017, to February 27, 2018. The positive matrix factorization(PMF) method and the FLEXible PARTicle(FLEXPART) model were employed to identify the sources of PM_(2.5). The results showed that the average mass concentration of PM_(2.5) was 111 μg/m^(3) during the observation period. Among the major WSIs, sulfate, nitrate, and ammonium(SNA) constituted 62% of the total PM_(2.5) mass, and NO_(3)^(-) ranked the highest with an average contribution of 24.6%. NH_(4)^(+) was abundant in most cases in Jiaozuo. According to chemical balance analysis, SO_(2)-4, NO_(3)^(-), and Cl^(-) might be present in the form of(NH_4)_(2)SO_4, NH_4NO_3, NH_4Cl, and KCl. The liquid-phase oxidation of SO_(2) and NO_(2) was severe during the haze period. The relative humidity and pH were the key factors influencing SO_(4)^(2-) formation. We found that NO_(3)^(-) mainly stemmed from homogeneous gas-phase reactions in the daytime and originated from the hydrolysis of N_(2)O_5 in the nighttime, which was inconsistent with previous studies. The PMF model identified five sources of PM_(2.5) : secondary origin(37.8%), vehicular emissions(34.7%), biomass burning(11.5%), coal combustion(9.4%), and crustal dust(6.6%). | Xiaoyong Liu Mingshi Wang Xiaole Pan Xiyue Wang Xiaolong Yue Donghui Zhang Zhigang Ma Yu Tian Hang Liu Shandong Lei Yuting Zhang Qi Liao Baozhu Ge Dawei Wang Jie Li Yele Sun Pingqing Fu Zifa Wang Hong He | 2021 | Journal of Environmental Sciences2021，33，5： | 5 |
| 6 | Tribological and tribochemical properties of magnetite nanoflakes as additives in oil lubricants显示文摘This detailed the tribological and tribochemical properties of magnetite(Fe_3O_4) nanoflakes used as additives in #40 base oil in a four-ball tribo-tester.The average friction coefficient of the friction pair for lubricant containing the Fe_3O_4 nanoflakes of 1.5 wt%as a lubricant additive in the base oil is decreased by18.06%compared to that of solely base oil.The chemical composition of base oil with the Fe_3O_4 nanoflake additives did not change during the 48-h friction assessment.The decreased saturation magnetization and increased coercivity of magnetite nanoflakes occurred due to the distortion of the basal planes and the presence of hematite(α-Fe_3O_4) generated by the tribochemical reactions during the friction process.The multi-layer low-shear-stress tribochemical lubrication films on the surface of the friction pair could form because the nanoflake particles arrange and adhere onto the surface of the friction pair in an orderly manner,and the tribochemical reactions of the friction pair in the presence of the nanoflakes occur as Fe→FeO→Fe_3O_4→γ-FeOOH →γ-Fe_2O_3→α-Fe_2O_3.The formation of the films can improve the tribological properties. | Longhua Xiang Chuanping Gao Yanmin Wang Zhidong Pan Dawei Hu | 2014 | Particuology2014，12，6： | 4 |
| 7 | Enhanced production of seed oil with improved fatty acid composition by overexpressing NAD^(+)-dependent glycerol-3-phosphate dehydrogenase in soybean显示文摘There is growing interest in expanding the production of soybean oils(mainly triacylglycerol, or TAG) to meet rising feed demand and address global energy concerns. We report that a plastidlocalized glycerol-3-phosphate dehydrogenase(GPDH), encoded by GmGPDHp1 gene, catalyzes the formation of glycerol-3-phosphate(G3 P), an obligate substrate required for TAG biosynthesis.Overexpression of GmGPDHp1 increases soybean seed oil content with high levels of unsaturated fatty acids(FAs), especially oleic acid(C18:1), without detectably affecting growth or seed protein content or seed weight. Based on the lipidomic analyses, we found that the increase in G3 P content led to an elevated diacylglycerol(DAG) pool, in which the Kennedy pathwayderived DAG was mostly increased, followed by PC-derived DAG, thereby promoting the synthesis of TAG containing relatively high proportion of C18:1. The increased G3 P levels induced several transcriptional alterations of genes involved in the glycerolipid pathways. In particular, genes encoding the enzymes responsible for de novo glycerolipid synthesis were largely upregulated in the transgenic lines, in-line with the identified biochemical phenotype. These results reveal a key role for GmGPDHp1-mediated G3 P metabolism in enhancing TAG synthesis and demonstrate a strategy to modify the FA compositions of soybean oils for improved nutrition and biofuel. | Ying Zhao Pan Cao Yifan Cui Dongxu Liu Jiapeng Li Yabin Zhao Siqi Yang Bo Zhang Runnan Zhou Minghao Sun Xuetian Guo Mingliang Yang Dawei Xin Zhanguo Zhang Xin Li Chen Lv Chunyan Liu Zhaoming Qi Jingyu Xu Xiaoxia Wu Qingshan Chen | 2021 | Journal of Integrative Plant Biology2021，63，6： | 4 |
| 8 | Mid-infrared chalcogenide microfiber knot resonators显示文摘A novel type of mid-IR microresonator,the chalcogenide glass(ChG)microfiber knot resonator(MKR),is demonstrated,showing easy fabrication,fiber-compatible features,resonance tunability,and high robustness.ChG micro fibers with typical diameters around 3μm are taper-drawn from As2S3 glass fibers and assembled into MKRs in liquid without surface damage.The measured Q factor of a typical 824μm diameter ChG MKR is about 2.84×104 at the wavelength of 4469.14 nm.The free spectral range(FSR)of the MKR can be tuned from2.0 nm(28.4 GHz)to 9.6 nm(135.9 GHz)by tightening the knot structure in liquid.Benefitting from the high thermal expansion coefficient of As2S3 glass,the MKR exhibits a thermal tuning rate of 110 pm·℃^-1 at the resonance peak.When embedded in polymethyl methacrylate(PMMA)film,a 551μm diameter MKR retains a Q factor of 1.1×10^4.The ChG MKRs demonstrated here are highly promising for resonator-based optical technologies and applications in the mid-IR spectral range. | YU XIE DAWEI CAI HAO WU JING PAN NING ZHOU CHENGUANG XIN SHAOLIANG YU PAN WANG XIAOSHUN JIANG JIANRONG QIU XIN GUO LIMIN TONG | 2020 | Photonics Research2020，8，4： | 3 |
| 9 | ASAF: altered spontaneous activity fingerprinting in Alzheimer’s disease based on multisite fMRI显示文摘Several monocentric studies have noted alterations in spontaneous brain activity in Alzheimer's disease (AD), although there is no consensus on the altered amplitude of low-frequency fluctuations in AD patients. The main aim of the present study was to identify a reliable and reproducible abnormal brain activity pattern in AD. The amplitude of local brain activity (AM), which can provide fast mapping of spontaneous brain activity across the whole brain, was evaluated based on multisite rs-fMRI data for 688 subjects (215 normal controls (NCs), 221 amnestic mild cognitive impairment (aMCI) 252 AD). Two-sample t-tests were used to detect group differences between AD patients and NCs from the same site. Differences in the AM maps were statistically analyzed via the Stouffer's meta-analysis. Consistent regions of lower spontaneous brain activity in the default mode network and increased activity in the bilateral hippocampus/parahippocampus, thalamus, caudate nucleus, orbital part of the middle frontal gyrus and left fusiform were observed in the AD patients compared with those in NCs. Significant correlations (P? | Jiachen Li Dan Jin Ang Li Bing Liu Chengyuan Song Pan Wang Dawei Wang Kaibin Xu Hongwei Yang Hongxiang Yao Bo Zhou Alexandre Bejanin Gael Chetelat Tong Han Jie Lu Qing Wang Chunshui Yu Xinqing Zhang Yuying Zhou Xi Zhang Tianzi Jiang Yong Liu Ying Han | 2019 | Science Bulletin2019，64，14： | 3 |
| 10 | Molecular Cloning and Bioinformatics Analysis of TypeⅢSecretion System Effector Protein Va1686 Gene of Vibrio alginolyticus显示文摘In this study,Va1686 gene was cloned from Vibrio alginolyticus. The total length of the gene is 1 164 bp,and it could encode 387 amino acids. The physicochemical properties,protein structure,genetic evolutionary relationship and antigenic characteristics of the effect protein Va1686 of V. alginolyticus HY9901 type Ⅲ secretion system were studied and analyzed by bioinformatics methods and tools. The results showed that Va1686 is a stable hydrophilic and acidic protein without a transmembrane region and a signal peptide,and secondary structure to α-helix. The evolutionary analysis showed that V. alginolyticus HY9901 and V.harveyi were clustered together,which indicated that the genetic relationship between the two species was the closest. Va1686 contains a Fic superfamily conserved domain associated with cell division. Bioinformatics analysis showed that the B-cell preponderant epitopes of Va1686 might be localized in the regions of 48-49,82-85,125-126,150-153,185-186,236-237 and so on. The 3D structure model of Va1686 subunit was simulated by SWISS-MODEL software and it was found that the vop S of V. parahaemolyticus was similar and the similarity was 89. 46%. In this study,the feasibility of Va1686 as a common antigen of Vibrio was verified from the perspective of bioinformatics,which laid the foundation for the next step in vaccine development. | Zhihao WU Mingjie FAN Jiaming LIAO Huanying PANG Chuanhao PAN Dawei SONG Mingsheng QIU Shuanghu CAI Jichang JIAN | 2018 | Agricultural Biotechnology2018，7，5： | 2 |
| 11 | Sewage irrigation increased methane and nitrous oxide emissions from rice paddies in southeast China显示文摘 | Jianwen Zou Shuwei Liu Yanmei Qin Genxing Pan Dawei Zhu | 2008 | Agriculture, Ecosystems and Environment2008，，4： | 2 |
| 12 | Role of MXene surface terminations in electrochemical energy storage:A review显示文摘MXenes are a group of recently discovered 2D materials and have attracted extensive attention since their first report in 2011;they have shown excellent prospects for energy storage applications owing to their unique layered microstructure and tunable electrical properties.One major feature of MXenes is their tailorable surface terminations(e.g.,-F,-O,-OH).Numerous studies have indicated that the composition of the surface terminations can significantly impact the electrochemical properties of MXenes.Nonetheless,the underlying mechanisms are still poorly understood,mainly because of the difficulties in quantitative analysis and characterization.This review summarizes the latest research progress on MXene terminations.First,a systematic introduction to the approaches for preparing MXenes is presented,which generally dominates the surface terminations.Then,theoretical and experimental efforts regarding the surface terminations are discussed,and the influence of surface terminations on the electronic and electrochemical properties of MXenes are generalized.Finally,we present the significance and research prospects of MXene terminations.We expect this review to encourage research on MXenes and provide guidance for usingthese materials for batteries and supercapacitors. | Zhuoheng Bao Chengjie Lu Xin Cao Peigen Zhang Li Yang Heng Zhang Dawei Sha Wei He Wei Zhang Long Pan Zhengming Sun | 2021 | Chinese Chemical Letters2021，32，9： | 2 |
| 13 | Physiological,Biochemical and Molecular Responses of Barley Seedlings to Aluminum Stress显示文摘Barley(Hordeum vulgare L.)is one of the most Aluminum(Al)sensitive cereal species.In this study,the physiological,biochemical,and molecular response of barley seedlings to Al treatment was examined to gain insight into Al response and tolerance mechanisms.The results showed that superoxide dismutase(SOD),peroxidase(POD)and catalase(CAT)activity were inhibited to different degrees following Al exposure.The MDA content also significantly increased with increasing Al concentrations.SRAP results indicated significant differences between Al treatments and controls in terms of SRAP profile,and the genomic template stability(GTS)decreased with increasing Al concentration and duration.These integrative results help to elucidate the underlying mechanisms that the barley response to Al toxicity. | Xiaoqin Zhang Tao Tong Bin Tian Yunxia Fang Jiangjie Pan Junjun Zheng Dawei Xue | 2019 | Phyton-International Journal of Experimental Botany2019，88，3： | 2 |
| 14 | Identification of a small molecule activator of novel PKCs for promoting glucose-dependent insulin secretion显示文摘用为能影响 Golgi 形态学的小分子的一幅基于图象的屏幕,我们识别一个小分子, Sioc145,它能扩大 Golgi 分隔空间并且支持蛋白质分泌物。更重要地, Sioc145 加强以一种葡萄糖依赖者方式的胰岛素分泌物。我们证明 Sioc145 有选择地激活新奇蛋白质 kinase C (nPKCs;并且) 然而并非常规 PKC (cPKCs;,我和 II ) 在 INS-1E insulinoma 房间。相反, PMA, cPKCs 和 nPKCs 的非选择的使活跃之物,支持葡萄糖集中的胰岛素分泌物独立人士。而且,我们证明 Sioc145 和 PMA 在动摇显示出微分能力房间膜,并且建议 Sioc145 KATP 隧道下游地在放大小径支持胰岛素分泌物。在胰腺的小岛,有 Sioc145 的处理提高胰岛素分泌物的第二个阶段。近到血浆膜的增加的胰岛素小粒在 Sioc145 处理以后被观察。最后,到糖尿病的 GK 老鼠的 Sioc145 的管理增加他们的浆液胰岛素层次并且改进葡萄糖忍耐。一起,我们的研究经由有选择地激活 nPKCs 作为新奇葡萄糖依赖者 insulinotropic 混合物识别 Sioc145。 | Shuai Han Heling Pan Jianhua Zhang Li Tan Dawei Ma Junying Yuan Jia-Rui Wu | 2011 | Cell Research2011，21，4： | 2 |
| 15 | Novel sulfhydryl functionalized covalent organic frameworks for ultra-trace Hg^(2+) removal from aqueous solution显示文摘Two kinds of novel sulfhydryl functionalized covalent organic frameworks were fabricated as adsorbents for the removal of ultra-trace concentrations of Hg^(2+)from water.The two kinds of sulfhydryl functionalized covalent organic frameworks were obtained via a thiol-ene click reaction between the thiol groups of trithiocyanuric acid(TTC)or bismuththiol(BMT)and vinyl groups on the surface of covalent organic frameworks.The material structure was characterized by XRD,SEM,EDS,FT-IR,BET,and TG analysis.Due to their rich sulfur content,both adsorbents(COF-SH-1 and COF-SH-2)exhibited a high level of selective Hg^(2+)removal from aqueous solution with maximum adsorption capacities of 763.4 mg g^(-1) and526.3 mg g^(-1),respectively.Furthermore,in the presence of ultra-low concentrations of Hg^(2+)both materials exhibited excellent performance,achieving rapid Hg^(2+)removal at concentrations from 10μg L^(-1) to less than 0.02 ng L^(-1).Analysis of the adsorption mechanism indicates that the sulfur containing chelating groups exhibit a strong binding capacity for Hg^(2+).Results show that the structure determines the performance,with the amount of adsorption sites being related to the adsorption capacity.Therefore,as sulfhydryl functionalized covalent organic frameworks contain an abundance of adsorption sites,these materials can effectively achieve the removal of ultra-low trace Hg^(2+)concentrations and have promising future application potential for the environmental detection of heavy metals. | Fei Pan Chunyi Tong Zhaoyang Wang Fenghua Xu Xiaofei Wang Baicheng Weng Dawei Pan Rilong Zhu | 2021 | Journal of Materials Science & Technology2021，，34： | 2 |
| 16 | Identification of candidate genes controlling fiber quality traits in upland cotton through integration of meta-QTL,significant SNP and transcriptomic data显示文摘Background:Meta-analysis of quantitative trait locus(QTL)is a computational technique to identify consensus QTL and refine QTL positions on the consensus map from multiple mapping studies.The combination of meta-QTL intervals,significant SNPs and transcriptome analysis has been widely used to identify candidate genes in various plants.Results:In our study,884 QTLs associated with cotton fiber quality traits from 12 studies were used for meta-QTL analysis based on reference genome TM-1,as a result,74 meta-QTLs were identified,including 19 meta-QTLs for fiber length;18 meta-QTLs for fiber strength;11 meta-QTLs for fiber uniformity;11 meta-QTLs for fiber elongation;and 15 meta-QTLs for micronaire.Combined with 8589 significant single nucleotide polymorphisms associated with fiber quality traits collected from 15 studies,297 candidate genes were identified in the meta-QTL intervals,20 of which showed high expression levels specifically in the developing fibers.According to the function annotations,some of the 20 key candidate genes are associated with the fiber development.Conclusions:This study provides not only stable QTLs used for marker-assisted selection,but also candidate genes to uncover the molecular mechanisms for cotton fiber development. | XU Shudi PAN Zhenyuan YIN Feifan YANG Qingyong LIN Zhongxu WEN Tianwang ZHU Longfu ZHANG Dawei NIE Xinhui | 2020 | Journal of Cotton Research2020，3，4： | 1 |
| 17 | Progress and challenges in the fabrication of DPS shells for ICF显示文摘To improve the quality of deuterated polystyrene(DPS)shells,the synthesis and purification of DPS as well as the fabrication of DPS shells are investigated.The molecular weight and molecular weight distribution,measured by GPC-MALLS,are about 350 kg mol^(-1) and less than 2.0,respectively.The results of TG and GC-MS indicate that the residual solvent is almost completely removed.DPS shells with;300 mm–2500 mmdiameter and;10 mm–100mmwall thickness are successfully prepared by a microfluidic device.The monodispersity of the diameter ismuchbetter than that of the wall thickness in a batch ofDPSshells.The vacuoles can be suppressed by both reducing hydrophilic residues in DPS and adding some salts into the outer water phase(W2).The defects appearing during the drying process decrease by heat treatment,ethanol exchange,and lowered drying temperature.The results presented in this work not only provide guidelines for the preparation of DPS shells of better quality,but also indicate challenges for the future. | Meifang Liu Yawen Huang Sufen Chen Dawei Pan Miao Chen Qiaomei Chu Yiyang Liu Qiang Yin Zhanwen Zhang | 2019 | Matter and Radiation at Extremes2019，4，1： | 1 |
| 18 | Virtual flight test techniques to predict a blended-wing-body aircraft in-flight departure characteristics显示文摘As one of the promising configurations of the next generation of commercial aircraft,research on departure characteristics of the Blended-Wing-Body(BWB)is of great signification to safe flight limits.A three-degree-of-freedom(3-DOF)virtual flight test in a wind tunnel has been implemented for a candidate configuration to predict the departure characteristics.The support mechanism,the test model and the control law of the virtual flight test are introduced.In order to show the relationship between virtual flight test and actual flight test,the similarity criterion is also given.In open loop,the model has mild oscillations in the longitudinal and lateral directions,which are stable in closed-loop.The effect of flight control has been verified in virtual flight and actual subscale flight test.The analysis of system identification results indicate that the model has a good response to the excitation signal,and the response is in reasonable agreement with the flight test.Finally,the virtual flight departure test results are compared with the flight test.It shows that there is a good correspondence between the angle of attack and the elevator deflection at departure.This gives promising evidence of the practicability of virtual flight testing to predict departure of a BWB. | Junquan FU Zhiwei SHI Zheng GONG Mark HLOWENBERG Dawei WU Lijun PAN | 2022 | Chinese Journal of Aeronautics2022，35，1： | 1 |
| 19 | Factors Associated with SARS-CoV-2 Repeat Positivity—Beijing,China,June–September 2020显示文摘Introduction:Repeat positive severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)following COVID-19 initial viral clearance(repositivity)poses a public health management challenge.The objective was to determine factors associated with neutralizing antibody(Nab)level and re-positivity among patients infected with a single strain SARS-CoV-2.Methods:During a single strain SARS-CoV-2 cluster in Beijing,China,longitudinal individual clinical,virological,and immunological data were collected from 368 infections from June 13 to September 22,2020.Factors associated with Nab level and re-positivity were analyzed using generalized estimating equations.Results:A total of 353(96%)SARS-CoV-2 infections had demographic,clinical,and laboratory data available.Among the 353 infections,55(15.5%)were re-positive,and blood draws were taken from 346 individuals(98.0%)during hospitalization and/or during the follow-up period.Symptoms were milder for the second-time admission for the re-positives,although 36.4%of re-positives presented with radiographic appearance of pneumonia manifestation.Compared to non-re-positive patients,NAb titers were lower among re-positives;NAb was positively associated with clinical severity.Samples from the lower respiratory tract manifested higher viral load than that from the upper respiratory tract.Multivariable analysis showed re-positivity was positively associated with being female[odd ratio(OR)=1.7,95%confidence interval(CI)1.1–2.8]and being aged<18 years(OR=5.2,95%CI 1.5–18.1);having initially asymptomatic infection(OR=13.7,95%CI 1.6–116.3);and negatively associated with a higher NAb level(OR=0.9,95%CI 0.5–1.7).Conclusions:NAb may be important for sustained viral clearance.Lower respiratory tract infection was associated with higher viral load among all infections when compared to upper respiratory tract infection.Continuous lower respiratory and intermittent upper respiratory viral shedding among COVID-19 infections may occur. | Siqi Li Xiaoli Wang Li Li Yang Pan Siyuan Yang Dawei Tan Ying Shen Peng Yang Naor Bar-Zeev Yaling Hu Jacky MJennings Simin Li Linghang Wang Quanyi Wang | 2022 | China CDC weekly2022，4，5： | 1 |
| 20 | Phage display selection of peptides that inhibit metastasis ability of gastric cancer cells with high liver-metastatic potential显示文摘 | Shengjuan Hu Xinning Guo Huahong Xie Yulei Du Yanglin Pan Yongquan Shi Jun Wang Liu Hong Shuang Han Dongtao Zhang Dawei Huang Kedong Zhang Feihu Bai Haiping Jiang Huihong Zhai Yongzhan Nie Kaichun Wu Daiming Fan | 2006 | Biochemical and Biophysical Research Communications2006，，4： | 1 |
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