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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Corrections to the scaling of the second-order structure function in isotropic turbulence显示文摘假定经常的偏斜度的 Obukhov 的途径被用来获得分析修正到可伸缩第二顺序结构功能,从 Kolmogorov 鈥檚 4/5 法律开始。这些修正能在明确的表达式,而非数字解决方案在被需要的模型应用程序被使用。有一个插值公式的比较由 Batchelor 求婚了,证明后者给令人惊讶地精确的结果。一样的方法到的修正获得分析修正到可伸缩的法律,考虑可能的修正由 intermittency 导致了,也被建议。关键词可伸缩法律 - 结构功能 - 各向同性的骚乱工程被中国的国家自然科学基础支持(10828204 并且 A020401 ) 并且 BUAA SJP 111 节目。 | Le Fang Wouter J. T. Bos Xiaozhou Zhou Liang Shao Jean-Pierre Bertoglio | 2010 | Acta Mechanica Sinica2010，26，2： | 6 |
| 3 | Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B显示文摘作为克积极的、形成孢子的厌氧的杆菌, Clostridium 顽固(C。顽固) 为严重、致命的 pseudomembranous 大肠炎负责,并且形成世界范围的最迫切的抗菌素抵抗威胁。流行 C。顽固全球性是联系抗菌素的腹泻的领先的原因,特别由于 hypervirulent 的出现,种类与高死亡和病态联系了的腹泻。TcdB,关键毒力因素之一由这个细菌藏匿了,通过糟糕理解的机制进入主人房间得到它的病原的效果。这里,我们报导 TcdB 细胞的受体的第一鉴定, chondroitin 硫酸盐 proteoglycan 4 (CSPG4 ) 。CSPG4 开始从屏蔽的一个整个染色体的人的 shRNAmir 图书馆被孤立,并且它的角色被证实由调停 TALEN 并且在人的房间的 CRISPR/Cas9-mediated 基因大美人。CSPG4 为对房间表面有约束力的 TcdB 是批评的,导致细胞骨架混乱和房间死亡。在 CSPG4 的 N 终点和 TcdB 的 C 终点之间的一个直接相互作用被证实,并且 CSPG4 的毒素绑定领域的可溶的肽能保护房间免受 TcdB 的行动的伤害。尤其是, CSPG4/NG2 的完全的损失减少了在没有显著地影响动物死亡的老鼠的被触发 TcdB 的 interleukin-8 正式就职。基于两个在里面 vitro 并且在 vivo 研究,我们为 TcdB endocytosis 建议一个双受体的模型。第一 TcdB 受体的发现为 CSPG4 揭示一个以前不受怀疑的角色并且为 C 的处理提供一个新治疗学的目标。顽固感染。 | Pengfei Yuan Hongmin Zhang Changzu Cai Shiyou Zhu Yuexin Zhou Xiaozhou Yang Ruina He Chan Li Shengjie Guo Shan Li Tuxiong Huang Gregorio Perez-Cordon Hanping Feng Wensheng Wei | 2015 | Cell Research2015，25，2： | 6 |
| 4 | 股票市场韧性与企业技术创新显示文摘本文从金融市场视角出发,创新性地利用Log-ACD模型、EGARCH模型、蒙特卡洛模拟法对股票市场韧性进行度量,在得到可靠韧性指标后,采用双向固定效应模型、中介效应模型系统性地论证了股票市场韧性对上市企业技术创新的理论假说、影响效果和作用机制。研究发现:(1)股票市场韧性的增强可以显著提升上市企业技术创新产出和效率,这一结果在更换技术创新度量指标、更换回归模型、控制随时间变化的解释变量因素、控制随和不随时间变化的行业或省份固定效应、面板交互固定效应以及工具变量估计等一系列稳健性检验后仍成立。(2)机制检验表明,股票市场韧性的增强不仅可以缓解企业技术创新面临的融资约束问题,增强大股东的风险承担水平,而且有助于机构投资者进入企业、显著优化企业的股权制衡,这些共同对上市企业技术创新水平施加积极影响。(3)扩展检验表明,与非高新技术企业、国有企业、境外上市企业相比,股票市场韧性对高新技术企业、非国有企业、境内上市企业的技术创新具有更为明显的正向激励作用。本文还根据研究结论就如何提高中国股票市场韧性,更好服务企业技术创新,提出了相关政策建议。 | 温军 李凌霄 Zhou Xiaozhou | 2023 | 数量经济技术经济研究2023，40，10： | 3 |
| 5 | Frameless stereotactic aspiration and thrombolysis of moderate thalamic hemorrhage显示文摘To the editor:Frameless stereotactic aspiration and thrombolysis (FSAT) is appropriate for treating deep-seated brain hematoma such as thalamic haemorrhage (TH).1 We performed FSAT to determine the efficacy and safety of this method for treating moderate TH (hematoma volume of 10-30 ml). From December 2006 to November 2011,a total of 75 consecutive moderate TH patients were enrolled in this study.These patients were non-randomly assigned to two groups,the FSAT group and the conservative group,according to the preference of physicians or patients.The study protocol was approved by the Medical Ethics Committee of the Third Affiliated Hospital of Soochow University.The final analysis included 27 patients in the FSAT group and 48 patients in conservative group. | Lian Xuegan Huang Hongwei Wu Jian Wei Ning Zhou Jianzhong Sheng Shiying He Xiaozhou | 2014 | Chinese Medical Journal2014，，12： | 2 |
| 6 | Multi-parameter quantitative assessment of 3D geological models for complex fault-block oil reservoirs显示文摘In the field of 3 D geologic modeling, researchers often pay more attention to modeling methods and workflows, but neglect the quantitative evaluation of models. If the evaluation is narrowed to the same reservoir type, the comparability and practicality of quantitative assessment will be emerging. The evaluation system should include three parts: data verification, geological understanding and process check. Data verification mainly involves testing the accuracy of local prediction with actual data, and geological understanding is to examine whether the global estimation honors geological principles and prior insights. Process check is also indispensable to avoid occasionality. To this end, we produced a set of assessment criteria, taking complex fault-block sandstone oil reservoir as an example. To be specific, thirteen characteristic parameters were totally selected, setting weights according to their rated importance, formulating three-level evaluation standards in a centesimal system for each characteristic parameter, and obtaining the final assessment based on the cumulative score. The results indicate that such evaluation can not only access the quality of the model objectively and comprehensively, but also identify the aspects in need of improvement through the deduction items. | TAN Xuequn LIU Yunyan ZHOU Xiaozhou LIU JiANDang ZHENG Rongchen JIA Chao | 2019 | Petroleum Exploration and Development2019，46，1： | 1 |
| 7 | Survival after radical cystectomy for bladder cancer:Multicenter comparison between minimally invasive and open approaches显示文摘Objective:To investigate oncological outcomes in patients with bladder cancer who underwent minimally invasive radical cystectomy(MIRC)or open radical cystectomy(ORC).Methods:We identified patients with bladder cancer who underwent radical cystectomy(RC)in 13 centers of the Chinese Bladder Cancer Consortium(CBCC).Perioperative outcomes were compared between MIRC and ORC.The influence of surgical approaches on overall survival(OS)and cancer-specific survival(CSS)in the entire study group and subgroups classified according to pathologic stage or lymph node(LN)status was assessed with the log-rank test.Multivariable Cox proportional hazard models were used to evaluate the association among OS,CSS and risk factors of interest.Results:Of 2098 patients who underwent RC,1243 patients underwent MIRC(1087 laparoscopic RC and 156 robotic-assisted RC,respectively),while 855 patients underwent ORC.No significant differences were noted in positive surgical margin rate and 90-day postoperative mortality rate.MIRC was associated with less estimated blood loss,more LN yield,higher rate of neobladder diversion,longer operative time,and longer length of hospital stay.There was no significant difference in OS and CSS according to surgical approaches(pZ0.653,and 0.816,respectively).Subgroup analysis revealed that OS and CSS were not significantly different regardless of the status of extravesical involvement or LN involvement.Multivariable Cox regression analyses showed that the surgical approach was not a significant predictor of OS and CSS.Conclusions:Our study showed that MIRC was comparable to conventional ORC in terms of OS and CSS. | Weibin Xie Junming Bi Qiang Wei Ping Han Dongkui Song Lei Shi Dingwei Ye Yijun Shen Xin Gou Weiyang He Shaogang Wang Zheng Liu Jinhai Fan Kaijie Wu Zhiwen Chen Xiaozhou Zhou Chuize Kong Yang Liu Chunxiao Liu Abai Xu Baiye Jin Guanghou Fu Wei Xue Haige Chen Tiejun Pan Zhong Tu Tianxin Lin Jian Huang | 2020 | Asian Journal of Urology2020，7，3： | 1 |
| 8 | QB50 Project and the Development of Cube Sat Technology in China显示文摘The Cube Sat refers to the low-cost nano satellite produced by international standards. The QB50 project is 'an International Network of 50 double Cube Sats for multi-point, in-situ, long-duration measurements in the lower thermosphere and re-entry research'. There are 23 countries and region participated in the QB50 Project. 38 Cube Sats were developed and launched. Among them, four Cube Sats developed by Chinese universities were sent to orbit(Three were deployed from the International Space Station, and one was launched by the Polar Satellite Launch Vehicle, PLSV). They are Aoxiang-1(Northwestern Polytechnical University, the Asia coordinator), Lilac Sat-1(Harbin Institute of Technology), NJUST-2(Nanjing University of Science and Technology) and NUDTsat(National University of Defense Technology). Through the development of the QB50 Project, Chinese researchers and students got in touch with the concept of Cube Sat and gained experience of international scientific cooperation. A lot of students took part in the assembly, integration, and test of spacecraft, which is helpful to the training of space talents. Now, many universities and institutes have the capabilities to develop Cube Sats and the subsystems independently. | ZHOU Jun LIU Yingying LIU Guanghui BAI Bo PANG Weijian ZHU Peijie YU Xiaozhou | 2018 | Aerospace China2018，19，2： | 1 |
| 9 | Development Status and Future Trend of CCUS:Supporting Policies and Business Models显示文摘In the background that countries all over the world have gradually reached the climate consensus and successively announce the goal of carbon neutrality,CCUS has been more prominently standing out with its necessity and importance to be an essential key technology to promote massive utilization of fossil fuels and reach sustainable development scenario,becoming flourished with a positive trend in recent years.Based on the analysis of the development status of CCUS,this paper focuses on the effective supporting policies and business models of both domestic and foreign banks,forms a judgment on the future trend of the industry,and puts forward relevant suggestions for the promotion of the CCUS industry. | Zhou Yanxi Zhang Xiaozhou Li Qiang | 2023 | China Oil & Gas2023，30，6： | 0 |
| 10 | Elevated expression of hepcidin post-renal ischemia reperfusion injury显示文摘 | Cuixing Zhou Xiaozhou He Dong Xue Nin Xu | 2013 | Acta Biochimica et Biophysica Sinica2013，45，4： | 0 |
| 11 | A new method to reduce end effect of linear induction motor显示文摘A new method to compensate the end effect of a linear induction motor (LIM) in low-speed maglev vehicles is proposed. With this method, the motors are close to each other so that the front motor's exit-end magnetic field extends into the next motor's entry zone. As a result, the motor's magnetic field traveling wave become continuous and the end effect of short primary LIMs is greatly weakened. In the analysis of the air-gap magnetic field distribution, the LIM is assumedly divided into two identical motors with the distances of 20, 40, 60, and 80 mm. The results show that the air-gap magnetic field is still continuous within these distances due to LIM's end effect. As the distance between two motors increases, the distortion of the air-gap magnetic field becomes more severe. Then, we investigate the relationship between the secondary speed and the thrust in three cases, i.e., a single LIM, two motors divided with 72 mm with pole pitch corrected, and two motors divided with 60 mm without the pole pitch being corrected. We find that the thrust has a small decrease when the speed increases, which means that the magnetic field is already continuous and its amplitude is approximately a constant. Furthermore, the thrust loss of case 3 is more than that of case 2, which indicates that the pole pitch correction is effective. | Xiaozhou GUO Bin ZHOU Jisan LIAN | 2012 | Journal of Modern Transportation2012，20，2： | 0 |
| 12 | Nutritional Value of Lippia nodiflora( L. ) Greene as Feed显示文摘To analyze the nutritional value as feed,the aerial stem and leaves of Lippia nodiflora( L.) Greene and Phyla nodiflora( L.) Greene were sampled to measure the nutritional indices. The nutritional indices were also compared with common forage grass,and the development value of L. nodiflora as feed was analyzed. Compared with P. nodiflora,L. nodiflora had obvious fast-growing and high-yield abilities. The contents of crude fat,crude fiber,crude ash,lysine,vitamin C,Ca,and Fe in L. nodiflora were obviously higher than that in P. nodiflora,but the content of crude protein and total P in L. nodiflora were significantly lower than that in P. nodiflora. Compared with common forage feed ryegrass,alfalfa,millet straw and corn straw,L. nodiflora had higher contents of crude fat and crude ash and lower contents of crude fiber and crude protein. Therefore,L. nodiflora had higher development value as feed. | Jiang Xuanbin Peng Xiu Geng Yanghui Zhou Xiaozhou Chen Daojing | 2014 | Animal Husbandry and Feed Science2014，6，2： | 0 |
| 13 | Application Study of Trajectory Plume Model in Atmospheric Environmental Impact Assessment显示文摘[Objective]The research aimed to study application of the trajectory plume model in atmospheric environmental impact assessment. [Method]Trajectory plume model was used to retrospectively evaluate regional atmospheric improvement degree by fuel gas desulfurization project in Mawan Power Plant of Shenzhen. On this basis,we analyzed applicability of the model in atmospheric prediction of the construction project. [Result] Under the situation of complex flow field and variable weather condition,the trajectory plume model displayed good prediction accuracy,together with the use of flow field diagnosis model. Under complex weather condition,this model could be complementary to atmospheric environmental quality prediction model recommended by new atmosphere guidelines,which had the value of popularization in future atmospheric environmental evaluation and planning. [Conclusion]Trajectory plume model had broad application potential in atmospheric environmental impact assessment. | Xiaobin Cai Baozhang Liu Xiaomao Yang Xiaozhou Zhou Liyong Mei | 2013 | Meteorological and Environmental Research2013，4，5： | 0 |
| 14 | MORPHOLOGY OF MELT SPINNING SUPERSATURATED B2 NiAl显示文摘MORPHOLOGYOFMELTSPINNINGSUPERSATURATEDB2NiAl￥SUNBaode;CHEXiaozhou;LINDongliang;ZHOUYaohe(DepartmentofMaterialsEngineering,Sha... | SUN Baode CHE Xiaozhou LIN Dongliang ZHOU Yaohe(Department of Materials Engineering,Shanghai Jiaotong University,Shanghai 20030,China)(Department of Materials Science,Shanghai Jiaotong University,Shanghai 200030,China) | 1996 | Acta Metallurgica Sinica(English Letters)1996，9，2： | 0 |
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