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| 1 | Field Relationships,Geochemistry,Zircon Ages and Evolution of a Late Archaean to Palaeoproterozoic Lower Crustal Section in the Hengshan Terrain of Northern China显示文摘The Hengshan complex forms part of the central zone of the North China Craton and consists predominantly of ductilely-deformed late Archaean to Palaeoproterozoic high-grade, partly migmatitic, granitoid orthogneisses, intruded by mafic dykes of gabbroic composition. Many highly strained rocks were previously misinterpreted as supracrustal sequences and represent mylonitized granitoids and sheared dykes. Our single zircon dating documents magmatic granitoid emplacement ages between 2.52 Ga and 2.48 Ga, with rare occurrences of 2.7 Ga gneisses, possibly reflecting an older basement. A few granitic gneisses have emplacement ages between 2.35 and 2.1 Ga and show the same structural features as the older rocks, indicating that the main deformation occurred after ~2.1 Ga. Intrusion of gabbroic dykes occurred at~1920 Ma, and all Hengshan rocks underwent granulite-facies metamorphism at 1.88-1.85 Ga, followed by retrogression, shearing and uplift.We interpret the Hengshan and adjacent Fuping granitoid gneisses as the lower, plutonic, part of a late Archaean to early Palaeoproterozoic Japan-type magmatic arc, with the upper, volcanic part represented by the nearby Wutai complex. Components of this arc may have evolved at a continental margin as indicated by the 2.7 Ga zircons. Major deformation and HP North China Craton collided to form the Trans-North China orogen. Shear zones in the Hengshan are interpreted as major lower crustal discontinuities post-dating the peak of HP metamorphism, and we suggest that they formed during orogenic collapse and uplift of the Hengshan complex in the late Palaeoproterozoic (<1.85 Ga). | A. KRONER S.A. WILDE P.J. O'BRIEN LI Jianghai C.W. PASSCHIER N.P. WALTE LIU Dunyi | 2005 | Acta Geologica Sinica(English Edition)2005,79,5: | 91 |
| 2 | AZF microdeletions associated with idiopathic and non idiopathic cases with cryptorchidism and varicocele显示文摘Aim:To identify submicroscopic interstitital deletions in azoospermia factor (AZF) loci in idiopathic and non-idiopathic cases of male infertility in Indians.Methos:One hundred and twenty two infertile males with oligozoospermia or azoospermia were included in this study.Semen analysis was done to determine the sperm density,i.e.,normospermia(>20million/mL),oligozoospermia(<20million/mL) or azoospermia.They were subjected to detailed clinical examination and endocrinological and cytogenetic study.Thirty G-banded metaphases were analyzed in the 122 cases and polymerase chain reaction (PCR) microdeletion analysis was done in 70 cytogenetically normal subjects.For this genomic DNA was extracted using peripheral blood.The STS primers tested in each case were sY84,sY86(AZFa);sY127,sY134(AZFb);sY254,sY255(AZFc).PCR amplifications found to be negative were repeated at least 3 times to confirm the deletion of a given marker.The PCR products were analyzed on a 1.8% agarose gel.Results:Eight of the 70 cades(11.4%) showed deletion of at least one of the STS markers.Deletions were detected in cases with known and unknown aetiology with bilateral severe testiculopathy and also in cryptorchid and varicocele subjects.Conclusion.AZF microdeletions were seen in both idiopathic and non-idiopathic cases with cryptorchidism and varicocele.The finding of a genetic aetiology in infertile men with varicocele and cryptorchidism suggests the need for molecular screening in non-idiopathic cases. | Rima Dada N.P. Gupta K. Kucheria | 2002 | Asian Journal of Andrology2002,4,4: | 22 |
| 3 | A study of local amplification effect of soil layers on ground motion in the Kathmandu Valley using microtremor analysis显示文摘Past researchers have anticipated the occurrence of a great earthquake in the central Himalayas in the near future.This may cause serious damage in the Kathmandu Valley,which sits on an ancient lake bed zone,with lacustrine sediments of more than 500 m depth.In this study,the predominant frequency of ground motion is evaluated using the Horizontal-to-Vertical(H/V) spectral ratio technique and recordings of ambient noise.The results of the H/V ratio show two peaks in about 20 percent of the locations,which are distributed mainly in and around the center and northern part of the Kathmandu Valley.The predominant frequencies vary from 0.5 Hz to 8.9 Hz in the study area,whereas the second resonance frequency varies from 4 Hz to 6 Hz in the center and northern part of the valley.This indicates that the center and northern part of the valley have a wide range of resonance frequency due to two levels of impedance contrast one may be from the surface layer and the other may be from the layer underneath.These two levels of resonance indicate the importance of considering the effects of surface and lower layers during the planning and designing of infrastructures in the Kathmandu Valley. | Paudyal Y.R. Yatabe R. Bhandary N.P. Dahal R.K. | 2012 | Earthquake Engineering and Engineering Vibration2012,11,2: | 7 |
| 4 | 4-甲基-1,2,3-噻二唑-5-甲酸芳酯的合成及生物活性显示文摘为了寻找高效广谱的植物激活剂候选化合物,以三乙胺为缚酸剂,通过4-甲基-1,2,3-噻二唑-5-甲酰氯与酚类化合物在二氯甲烷中于室温下反应,制得一系列共20个4-甲基-1,2,3-噻二唑-5-甲酸芳酯化合物,其中9个化合物未见文献报道,所有化合物的结构均得到了核磁共振氢谱、红外光谱、高分辨质谱的表征和确认。选择化合物2g培养了单晶,利用X-射线单晶衍射确证了该类化合物的空间结构。杀菌活性测定结果表明:部分化合物在50μg/mL下具有显著的离体杀菌活性,其中化合物2c,2n和2o具有广谱的杀菌活性,其EC50值在3.46~23.30μg/mL之间。生物活性测定结果表明,部分化合物显示了较好的抗病毒活性,大部分化合物对烟草花叶病毒(TMV)具有较好的钝化效果,2a,2c,2d,2e,2f,2g,2l,2o具有较好的诱导烟草抗TMV的活性。 | 王守信 米娜 范志金 付一峰 黄云 王唤 张正财 张聚方 宋海斌 BELSKAYA N.P. BAKULEV V.A. | 2010 | 农药学学报2010,12,3: | 4 |
| 5 | 人类认知的局限与跨文化传播——一个致力于跨文化融洽交流的计划显示文摘本文就世界文化课程内容的具体设置 ,及联合大学与传媒以更好实现课程积极目标等问题进行了探讨。文中通过多层次的论证强调指出 :人们始终持有相异或相冲突的宗教、哲学以及意识形态 ,尚没有一种普世真理足以使世间所有人心悦诚服。即便是广泛接受和运用中的科学知识 ,其发展亦受阻于人类本身的局限而不可确定。尽管科学在前沿问题研究上竞争激烈 ,也仍然无法回答和消除所有的问题和差异。因此 ,从全球或泛人类立场观之 ,人类现有的知识与理解能力具有不确定和不完整的特点 ,而这样的特点浸透在所有的具体文化信仰之中。认识到共同局限性的人们———尤其是政界的领导人———亟需摒弃极端的文化分离思想 ,以更宽容理解的心态进行思考和行动 。 | J.Z.埃德蒙森 N.P.埃德蒙森 | 2004 | 现代传播(北京广播学院学报)2004,,4: | 4 |
| 6 | Synthesis,Crystal Structure and Biological Activity of N-tert-butyl-N-(4-methyl-1,2,3-thiadiazole)-5-yl-N’-(4-methyl-1,2,3-thiadiazole)-5-formyl-N’-3,5-dichloropyridin-2-yl-diacylhydrazine显示文摘The title compound N-tert-butyl-N-(4-methyl-1,2,3-thiadiazole)-5-yl-N'-(4-me-thyl-1,2,3-thiadiazole)-5-formyl-N'-3,5-dichloropyrid-2-yl-diacylhydrazines (C18H17Cl2N7O3S2, Mr = 514.41) has been synthesized by the reaction of N-tert-butyl-N'-3,6-dichloropyridine-2-formyl hydrazine with 4-methyl-1,2,3-thiadiazole-5-carbonyl chloride and triethylamine, and its structure was characterized by 1H NMR, HR MS, and single-crystal X-ray diffraction. The crystal of the title compound belongs to monoclinic, space group C2/c with a = 27.726(8), b = 11.045(3), c = 14.507(4), β = 96.758(4)°, Z = 8, V = 4412(2) 3, Dc = 1.549 g/cm3, μ = 0.521 mm-1, F(000) = 2112, R = 0.0405 and wR = 0.1153. X-ray analysis indicates that all rings are non-planar in this molecule. The bioassay results indicate that both the title compound and the positive control RH-5992 have weak fungicide activities, while the title compound has good insecticidal activity against Plutella xylostella L. and no insecticidal activity against Culex pipiens pallens. | 王唤 付一峰 范志金 宋海斌 吴青君 张友军 Belskaya N.P. Bakulev V.A. | 2011 | Chinese Journal of Structural Chemistry2011,30,3: | 2 |
| 7 | Synthesis,Crystal Structure,and Biological Activity of Naphthalen-2-yl4-methyl-1,2,3-thiadiazole-5-carboxylate显示文摘The title compound naphthalen-2-yl-4-methyl-1,2,3-thiadiazole-5-carboxylate (C 14 H 10 N 2 O 2 S,M r=270.31) was synthesized by the reaction of 4-methyl-1,2,3-thiadiazole-5-carbonyl chloride with 2-naphthol,and its structure was characterized by IR,1 H NMR,high-resolution mass spectrometry and single-crystal X-ray diffraction.The crystal belongs to orthorhombic,space group Pbcn with a=23.475(5),b=9.6640(19),c=10.814(2),β=90.00°,Z=8,V=2453.2(9) 3,M r=270.30,D c=1.464 g/cm 3,μ=0.262 mm-1,F(000)=1120,R=0.0444 and wR=0.1099.X-ray analysis revealed that the thiadiazole and naphthalene rings were non-planar,while the thiadiazole ring and the ester group were essentially planar,and two intermolecular hydrogen bonds C(6) H(6)···O(1) and C(14) H(14)···O(1) were observed.The preliminary biological test showed that the title compound had antifungal and antivirus activities against tobacco mosaic virus. | 王守信 付一峰 范志金 米娜 张海科 宋海斌 Belskaya N.P. Bakulev V.A. | 2011 | Chinese Journal of Structural Chemistry2011,30,2: | 2 |
| 8 | Simulation of full-scale ice–structure-interaction by an extended Matlock-model显示文摘 | M. Withalm N.P. Hoffmann | 2009 | Cold Regions Science and Technology2009,,2: | 2 |
| 9 | Cyclooxygenase inhibitory and antioxidant cyanidin glycosides in cherries and berries显示文摘 | N.P. Seeram R.A. Momin M.G. Nair L.D. Bourquin | 2001 | Phytomedicine2001,,5: | 2 |
| 10 | Association of Lp-PLA2 with digital reactive hyperemia, coronary flow reserve, carotid atherosclerosis and arterial stiffness in coronary artery disease显示文摘 | Ignatios Ikonomidis Nikolaos N.P. Kadoglou Vlassis Tritakis Ioannis Paraskevaidis Kleanthi Dimas Paraskevi Trivilou Ioannis Papadakis Stavros Tzortzis Helen Triantafyllidi John Parissis Maria Anastasiou-Nana John Lekakis | 2014 | Atherosclerosis2014,,1: | 2 |
| 11 | 骨传导刺激产生的前庭诱发眼外电位 | Rosengren S.M. McAngus Todd N.P. Colebatch J.G. 李一明 | 2005 | 世界核心医学期刊文摘(神经病学分册)2005,0,11: | 2 |
| 12 | Ugi反应合成4-甲基-1,2,3-噻二唑化合物及其抗烟草花叶病毒活性(英文)显示文摘为了寻找更多高活性化合物和进行先导结构的衍生,利用Ugi反应设计合成了18个4-甲基-1,2,3-噻二唑新化合物(I-1~I-18),其结构均经核磁共振氢谱、红外光谱和高分辨质谱的表征和确认。杀菌、抗病毒以及诱导活性的筛选结果表明:目标化合物I-3和I-11抗烟草花叶病毒(TMV)的半叶法活性高于对照药剂病毒唑,I-6的保护活性和钝化活性高于病毒唑,I-12的治疗活性高于病毒唑,I-16的诱导活性高于对照药剂噻酰菌胺;氟原子的引入有利于保持和提高新化合物的抗病毒活性,4-甲基-1,2,3-噻二唑和氟原子是新化合物抗病毒的重要活性亚结构单元。Ugi反应是新农药创制中先导优化的绿色手段。 | 付一峰 左翔 范志金 米娜 郑琴香 黄云 王唤 黄杰 BELSKAYA N.P. BAKULEV V.A. MORZHERIN Yu.Yu. PROKHOROVA P.E. | 2010 | 农药学学报2010,12,4: | 2 |
| 13 | Antioxidant properties and quantitative UPLC-MS analysis of phenolic compounds from extracts of fenugreek ( Trigonella foenum-graecum ) seeds and bitter melon ( Momordica charantia ) fruit显示文摘 | O. Kenny T.J. Smyth C.M. Hewage N.P. Brunton | 2013 | Food Chemistry2013,,: | 2 |
| 14 | Laparoscopic Versus Open Radical Nephrectomy for Large Renal Tumors: A Long-Term Prospective Comparison显示文摘 | A.K. Hemal A. Kumar R. Kumar P. Wadhwa A. Seth N.P. Gupta | 2007 | The Journal of Urology2007,,: | 1 |
| 15 | A feature of the reaction between Al and SiC particles in an MMC显示文摘 | T. Sritharan L.S. Chan L.K. Tan N.P. Hung | 2001 | Materials Characterization2001,,1: | 1 |
| 16 | Review of gas diffusion cathodes for alkaline fuel cells显示文摘 | F. Bidault D.J.L. Brett P.H. Middleton N.P. Brandon | 2008 | Journal of Power Sources2008,,1: | 1 |
| 17 | Myasthenia gravis:a population based epidemiological study in Cambridgeshire显示文摘 | Robertson N.P. Deans | | 0,,: | 1 |
| 18 | Tissue distribution and characterization of predominant hemolymph carrier proteins from Dermacentor variabilis and Ornithodoros parkeri显示文摘 | N.P. Gudderra D.E. Sonenshine C.S. Apperson R.M. Roe | 2002 | Journal of Insect Physiology2002,,2: | 1 |
| 19 | Mechanical behavior of zirconia/alumina composites显示文摘 | S.R. Choi N.P. Bansal | 2004 | Ceramics International2004,,1: | 1 |
| 20 | Ganoderma lucidum ameliorate mitochondrial damage in isoproterenol-induced myocardial infarction in rats by enhancing the activities of TCA cycle enzymes and respiratory chain complexes显示文摘 | N.P. Sudheesh T.A. Ajith K.K. Janardhanan | 2011 | International Journal of Cardiology2011,,: | 1 |