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| 1 | Apoptosis and its relationship with cell proliferation,p53,Waf1p21,bcl-2 and c-mycin esophageal carcinogenesis studied with a high-risk population in northern China显示文摘Apoptosisanditsrelationshipwithcelproliferation,p53,Waf1p21,bcl2andcmycinesophagealcarcinogenesisstudiedwithahighriskpopul... | WANG LiDong1, ZHOU Qi1, WEI JunPing1, YANG WanCai1, ZHAO Xin1, WANG LiXia1, ZOU Jian Xiang1, GAO ShanShan1, LI YongXin1 and YANG C.S.2Keywords esophageal neoplasms apoptosis precancerous lesions Waf1 p21 gene p53 | 1998 | World Journal of Gastroenterology1998，4，4： | 295 |
| 2 | 循证指南:弥散和灌注MRI在急性缺血性卒中诊断中的作用美国神经病学学会治疗和技术评价委员会的报告显示文摘目的 评价弥散加权成像(diffusion-weighted imaging,DWI)和灌注加权成像(perfusionweighted imaging PWI)在急性缺血性卒中患者诊断中应用的证据.方法 对1966年至2008年1月期间有关DWI和PWI诊断和预后价值的文献进行系统分析.结果和推荐 对于发病12 h内的急性缺血性卒中的诊断,DWI已被确认为有效的评价手段,且其诊断价值应高于非增强CT.为了最准确地诊断急性缺血性卒中,应进行DWI(A级推荐);然而,在疑似急性卒中患者的总体样本中,DWI诊断缺血性卒中的敏感性并不完美.DWI诊断脑出血的准确性不在本指南的范围之内.根据Ⅱ级和Ⅲ级证据,基线DWI体积可预测前循环卒中的基线卒中严重程度(B级推荐),但不能预测椎基底动脉系统卒中的基线卒中严重程度(C级推荐).基线DWI病变体积可预测(最终)梗死体积(B级推荐),并且有可能预测早期和远期临床转归(C级推荐).与DWI相比,基线PWI体积预测基线卒中严重程度的价值较小(C级推荐).尚无足够的证据支持或反对PWI在急性缺血性卒中诊断中的价值(U级推荐). | P.D. Schellinger R.N. Bryan L.R. Caplan J.A. Detre R.R. Edelman C. Jaigobin C.S. Kidwell J.P. Mohr M. Sloan A.G. Sorensen S. Warach 章娟娟(译) 王国颖(译) 汪凯(译) | 2010 | 国际脑血管病杂志2010，18，11： | 38 |
| 3 | Proteomics Technologies and Challenges显示文摘Proteomics is the study of proteins and their interactions in a cell. With the completion of the Human Genome Project, the emphasis is shifting to the protein compliment of the human organism. Because proteome reflects more accurately on the dynamic state of a cell, tissue, or organism, much is expected from proteomics to yield better disease markers for diagnosis and therapy monitoring. The advent of proteomics technologies for global detection and quantitation of proteins creates new opportunities and challenges for those seeking to gain greater understanding of diseases. High-throughput proteomics technologies combining with advanced bioinformatics are extensively used to identify molecular signatures of diseases based on protein pathways and signaling cascades. Mass spectrometry plays a vital role in proteomics and has become an indispensable tool for molecular and cellular biology. While the potential is great, many challenges and issues remain to be solved, such as mining low abundant proteins and integration of proteomics with genomics and metabolomics data. Nevertheless, proteomics is the foundation for constructing and extracting useful knowledge to biomedical research. In this review, a snapshot of contemporary issues in proteomics technologies is discussed. | William C.S. Cho | 2007 | Genomics, Proteomics & Bioinformatics2007，5，2： | 17 |
| 4 | Optimization of N18 Zirconium Alloy for Fuel Cladding of Water Reactors显示文摘In order to optimize the microstructure and composition of N18 zirconium alloy(Zr-1Sn-0.35Nb-0.35Fe-0.1Cr,in mass fraction,%),which was developed in China in 1990s,the effect of microstructure and composition variation on the corrosion resistance of the N18 alloy has been investigated.The autoclave corrosion tests were carried out in super heated steam at 400 ℃/10.3 MPa,in deionized water or lithiated water with 0.01 mol/L LiOH at 360 ℃/18.6 MPa.The exposure time lasted for 300-550 days according to the test temperature.The results show that the microstructure with a fine and uniform distribution of second phase particles(SPPs),and the decrease of Sn content from 1%(in mass fraction,the same as follows) to 0.8% are of benefit to improving the corrosion resistance;It is detrimental to the corrosion resistance if no Cr addition.The addition of Nb content with upper limit(0.35%) is beneficial to improving the corrosion resistance.The addition of Cu less than 0.1% shows no remarkable influence upon the corrosion resistance for N18 alloy.Comparing the corrosion resistance of the optimized N18 with other commercial zirconium alloys,such as Zircaloy-4,ZIRLO,E635 and E110,the former shows superior corrosion resistance in all autoclave testing conditions mentioned above.Although the data of the corrosion resistance as fuel cladding for high burn-up has not been obtained yet,it is believed that the optimized N18 alloy is promising for the candidate of fuel cladding materials as high burn-up fuel assemblies.Based on the theory that the microstructural evolution of oxide layer during corrosion process will affect the corrosion resistance of zirconium alloys,the improvement of corrosion resistance of the N18 alloy by obtaining the microstructure with nano-size and uniform distribution of SPPs,and by decreasing the content of Sn and maintaining the content of Cr is discussed. | B.X. Zhou M. Y. Yao Z.K. Li X.M. Wang J. Zhoua C.S. Long Q. Liu B.F. Luan | 2012 | Journal of Materials Science & Technology2012，28，7： | 13 |
| 5 | CORROSION BEHAVIOR OF A ZIRCONIUM-TITANIUM BASED PHOSPHONIC ACID CONVERSION COATING ON AA6061 ALUMINIUM ALLOY显示文摘变换涂层被在 fluorotitanate/zirconate 酸和氨基的 trimethylene 蘸 AA6061 形成在房间温度的磷的酸(ATMP ) 答案。形成进程和变换涂层的耐蚀性能分别地用电气化学的测试和盐水花测试(SST ) 被调查。电气化学的测试证明 Zr/Ti 和 ATMP 涂层像铬酸盐一样改进 AA6061 的腐蚀抵抗() SST 的结果显示出的 coating.But Zr/Ti 和 ATMP 涂层的腐蚀抵抗不像铬酸盐一样() coating.The 腐蚀区域在 72 以后是不到2%h 。 | S.H. Wang C.S. Liu F.J. Shan | 2008 | Acta Metallurgica Sinica(English Letters)2008，21，4： | 11 |
| 6 | CORROSION RESISTANCE OF HOT DIP GALVANIZED STEEL PRETREATED WITH BIS-FUNCTIONAL SILANES MODIFIED WITH NANOALUMINA显示文摘热剧降的腐蚀行为电镀了有二度的钢 pretreated --[ triethoxy-silylpropyl ]与氧化铝粒子修改的 tetrasulfide ( BTESPT )是 passiving 电影的 studied.The 腐蚀电阻被 Tafel 极化曲线和在电镀的钢底层上形成的电气化学的阻抗 spectroscopy.The 电影评估被 Fourier 变换描绘红外线的光谱学并且精力对待的热剧降的散X光检查 spectrometry.The 表面形态学电镀了钢预告的处理与 nanoalumina 粒子根据 silane 电影修改了的结果表演减少了阳极并且 cathodic 水流密度,和在测量频率的增加的全部的阻抗,因而为电镀的钢在在与铬酸盐电影和 silane 相比的 NaCl 答案的沉浸期间拍摄的热剧降改进腐蚀保护。 | F.J. Shan C.S. Liu S.H. Wang G.C. Qi | 2008 | Acta Metallurgica Sinica(English Letters)2008，21，4： | 9 |
| 7 | MICROSTRUCTURE AND PROPERTIES OF HIGH BORON BEARING STEEL显示文摘High boron bearing steel, in which boron homogeneously distributed, was successfully produced in the vacuum induction furnace. The microstructural observations of cast and hot rolled steels showed that the addition of titanium can eliminate the quantity of ferrous borides precipitated at the grain boundaries and break the net microstructure, as a result, its hot workability is improved. The titanium boride TiB2 homogeneously distributes in the matrix of a-Fe. The parameters of hot rolling process. including preheated temperature, initial rolling temperature, finished rolling temperature and the total deformation, have been optimized. | C.S. Liu, S. Y. Chen, Z. T. Wang, B. Yu and Q.K. Cai School of Materials and Metallurgy, Northeastern University, Shenyang 110006, China | 2002 | Acta Metallurgica Sinica(English Letters)2002，15，2： | 8 |
| 8 | 冲刷环境对桥墩冲刷空间形态影响的仿真分析显示文摘为研究环境对桥墩冲刷的影响,基于K-ε湍流模型建立了桥墩冲刷及冲刷环境数值仿真模型.对其三维仿真建模过程中的4个关键问题分别进行深入研究并提出优选的解决方法,特别关注三维边界条件的动态更新以及计算收敛性的算法改进.进而利用B.W.Melville经典实验对提出的桥墩冲刷精细化仿真方法从空间形态的角度进行多方面准确性验证.最后基于该精细化仿真方法,对CFD计算软件Fluent二次开发,进行精细化参数分析.计算结果表明:桥墩尺寸与最大冲刷深度以及流速与最大冲刷深度均存在近似线性关系,选择合适的桥墩形式、降低桥墩有效宽度、降低墩前水流流速以及选择合适的水流深度均可明显降低桥墩冲刷深度.不同冲刷环境参数取值对桥墩冲刷空间形态所产生的不同影响可以为桥墩主动抗冲刷设计与选型提供合理的理论基础与依据. | 熊文 姚浩 CAI C.S. 叶见曙 | 2016 | 哈尔滨工业大学学报2016，48，3： | 8 |
| 9 | 过瘤胃蛋白和氨基酸对奶牛、绵羊干物质采食量、消化率和生长性能的影响显示文摘数量充足和配比合理的营养对家畜生产性能起着决定性作用,其中蛋白质是动物生长发育、繁殖性能的主要限制因素之一。蛋白质的种类和水平决定着动物机体组成及日粮中必需氨基酸的供应。对反刍动物来说,蛋白质的作用是双方面,既要满足瘤胃厌氧微生物发酵的需要,又要满足动物成长的营养需要。然而,由于瘤胃的发酵作用,日粮中绝大多数蛋白质在瘤胃内被降解(称为瘤胃降解蛋白,RDP),只有小部分能通过瘤胃在小肠内吸收(称为非瘤胃降解蛋白,RUP),因此用于厌氧合成微生物蛋白的RDP以及RUP的种类决定了反刍动物日粮和机体必需氨基酸的利用率。微生物蛋白和过瘤胃蛋白决定了高产动物日粮中必需氨基酸的供应。因此,饲喂过瘤胃蛋白和氨基酸被认为是满足反刍动物生理以及生产需要的有效方法。文章综述了过瘤胃蛋白、过瘤胃赖氨酸和过瘤胃蛋氨酸在反刍动物上的应用,以及对奶牛、绵羊干物质采食量、消化率、生产性能影响的研究。蛋白质是反刍动物重要的限制性营养,由RDP和RUP组成。瘤胃微生物通过将RDP降解成小肽、氨基酸和氨等来合成微生物蛋白,其数量主要受日粮中瘤胃发酵率的制约。因此,RDP和RUP或氨基酸的供应对于满足反刍动物营养需要非常重要,尤其是对于饲喂低水平日粮的反刍动物。添加瘤胃保护蛋白和瘤胃保护氨基酸(特别是赖氨酸和蛋氨酸)能提高奶牛、绵羊的干物质采食量和消化率。同时,还能够提高生长性能、繁殖效率和产奶量。不管是单独添加,还是与赖氨酸同时添加,如果蛋氨酸的添加量大于肠道的可消化吸收量时,则有可能会产生负面影响。在奶牛泌乳早期的低蛋白水平日粮中添加蛋氨酸,能避免奶牛长期的不良反应。总而言之,反刍动物在低营养水平下添加瘤胃保护蛋白质和氨基酸,能提高饲料采食量、消化率以及生长性能。 | Ali C.S. I.Din M.Sharif M.Nisa A.Javaid N.Hashmi M.Sarwar 阳艳林 黄广明 | 2011 | 饲料与畜牧(新饲料)2011，，3： | 7 |
| 10 | STOCHASTIC CRACKING AND HEALING BEHAVIORS OF THIN FILMS DURING REACTION-DIFFUSION GROWTH显示文摘The stochastic cracking and healing behaviors of reaction-diffusion growth of thin films were studied by means of Markov processes analysis. We chose the thermal growth of oxide scales on metals as an example of reaction-diffusion growth. The thermal growth of oxide films follows power law when no cracking occurs. Our results showed that the growth kinetics under stochastic cracking and healing conditions was different from that without cracking. It might be altered to either pseudo-linear or pseudo-power laws dependent upon the intensity and frequency of the cracking of the films. When the hoping items dominated, the growth followed pseudo-linear law; when the diffusional items dominated, it followed pseudo-power law with the exponentials lower than the intrinsical values. The numerical results were in good agreement with the meassured kinetics of isothermal and cyclic oxidation of NiAl-0.1 Y (at. %) alloys in air at 1273K. | S.L. Zhu, S.L. Yang, Y.M. Xiong, M.S. Li, S.J. Geng, C.S. Hu, Fuhui Wang and W.T. Wu (State Key Lab for Corrosion and Protection, Institute of Metal Research, The Chinese Academy of Sciences, Shenyang 110016, China) | 2001 | Acta Metallurgica Sinica(English Letters)2001，14，6： | 6 |
| 11 | COMPRESSIBILITY BOUNDARY LAYER THEORY AND ITS SIGNIFICANCE IN COMPUTATIONAL HYDRODYNAMICS显示文摘COMPRESSIBILITYBOUNDARYLAYERTHEORYANDITSSIGNIFICANCEINCOMPUTATIONALHYDRODYNAMICS￥CharlesC.S.Song(UniversityofMinnesota,Minnea... | Charles C.S. Song(University of Minnesota, Minneapolis Minnesota 55455, USA) | 1996 | Journal of Hydrodynamics1996，8，2： | 5 |
| 12 | Composition and phase structure dependence of mechanical and magnetic properties for AlCoCuFeNi_x high entropy alloys显示文摘In this study, the effects of composition and phase constitution on the mechanical properties and magnetic performance of AlCoCuFeNix(x = 0.5, 0.8, 1.0, 1.5, 2.0, 3.0 in molar ratio) high entropy alloys(HEAs)were investigated. The results show that Ni element could lead to the evolution from face centered cubic(FCC), body centered cubic(BCC) and ordered BCC coexisting phase structure to a single FCC phase. The change of phase constitution enhances the plasticity but reduces the hardness and strength. One of the interesting points is the excellent soft magnetic properties of AlCoCuFeNixHEAs. Soft magnetic performance is dependent on composition and phase transition. AlCoCuFeNi1.5 alloy, achieving a better balance of mechanical and magnetic properties, could be applied as structure materials and soft magnetic materials(SMMs). High Curie temperature(>900 K) and strong phase stability below 1350 K of AlCoCuFeNi0.5 alloy confirm its practicability in a high-temperature environment. Atomic size difference(δ) is utilized as the critical parameter to explain the lattice strain and phase transformation induced by Ni addition. | Cong Liu Wenyi Peng C.S. Jiang Hongmin Guo Jun Tao Xiaohua Deng Zhaoxia Chen | 2019 | Journal of Materials Science & Technology2019，35，6： | 5 |
| 13 | 吸烟与非吸烟非小细胞肺癌患者的癌症研究 美国癌症研究学会(AACR)2009年会快报显示文摘第100届AACR年会于2009年4月18日-22日在美国丹佛市举行,17000多名从事癌症基础研究、转化研究和临床研究的人员参加了此次会议,在此对人们感兴趣的众多领域的最新进展进行了交流和探讨。会议报道了肿瘤学和相关医学科学的最新研究动态。其中涵盖一系列不同议题,包括从基础研究到某些癌症目前未知的发病机理和机制的探索。作为肺癌最常见的类型,非小细胞肺癌(NSCLC)的相关报告是本次会议的重要组成部分。一些研究开始关注于有或无吸烟史的NSCLC患者的分子生物学方面。而且,治疗NSCLC的现有和在研药物疗效的研究结果也是会议重要议题。本会议报告旨在为读者提供2009年AACR年会上关于吸烟与非吸烟NSCLC患者研究成果的概述。 | William C.S. Cho 李军 南娟 王洲 | 2009 | 中国肺癌杂志2009，12，10： | 5 |
| 14 | 经皮肝穿光动力疗法治疗晚期胆管癌的前瞻性研究和胆管内超声在评估疗效方面的作用 | Shim C.S. Cheon Y.K. 徐小洁 | 2005 | 世界核心医学期刊文摘(胃肠病学分册)2005，0，9： | 5 |
| 15 | 伴有或不伴有肝实质侵犯的卵巢癌周围性转移CT检出的敏感性与特异性研究显示文摘目的回顾性确定由不同经验水平的放射医生读片时,伴有或不伴肝实质侵犯(LPI)的卵巢癌病人肝周围性转移CT鉴别的敏感性与特异性。研究以剖腹探查分期及病理检查为参考标准。方法学院医学伦理委员会批准此项研究不必签署知情同意书,研究符合HIPAA要求。121例卵巢癌病人(年龄29~94岁,平均57.8岁)纳入本研究。2位放射医生(放射医生1:6个月专业经验;放射医生2:2年6个月专业经验)在不知道病人临床资料情况下,相互独立地回顾性记录CT显示是否有周围性转移, | O. Akin E. Sala C.S. Moskowitz N. Ishill R.A. Soslow D.S. Chi 唐光健(译) | 2008 | 国际医学放射学杂志2008，31，5： | 4 |
| 16 | IMPROVING THE SURFACE PROPERTY OF TC4 ALLOY BY LASER NITRIDING AND ITS MECHANISM显示文摘激光和激烈的氮的混合技术被使用改进钛合金(TC4 ) 的表面坚硬。样品是有 6.5 × 1 的激光力量密度的 nitrided 0 5 W · c m −2, 从 100 各种各样的扫描速度到在 −1 的 500mm · m。氮气体被预热到 300 ° C 加速 nitriding 过程。一些感兴趣的样品与 XRD 方法(X 光检查衍射) 被测试分析氮化物的作文,并且 HV 的表面坚硬被测量。结果显示出那听和 Ti 2 N 与合适的 nitriding 参数在 Ti 合金的表面上被形成,但是锡是主要作文。表面坚硬到三次增加了,它从 269 的原来的价值到 794kg · m m −2 。混合技术的机制被激光力量和加速了 nitriding 过程的预热过程主要氮的激活考虑。nitridation 过程能被看作详细给的六步。由分析改进 TiAl 合金的表面性质的机制的结果由于二个因素显示出表面性质的改进:第一个原因是激光退火的结果,并且第二是锡的形成。 | Y.L. Yang G.J. Zhao D. Zhang C.S. Liu | 2006 | Acta Metallurgica Sinica(English Letters)2006，19，2： | 4 |
| 17 | An Inverse Approach for Extracting Elastic-plastic Properties of Thin Films from Small Scale Sharp Indentation显示文摘An inverse method for extracting the elastic-plastic properties of metallic thin films from instrumented sharp indentation has been proposed in terms of dimensional analysis and finite element modeling.A wide range of materials with different elastic modulus,yield strength,and strain-hardening exponent were examined.Similar to the Nix-Gao model for the depth dependence of hardness H,(H/H0)2=1+h*Hh,the relationship between elastic modulus E and indentation depth h can be expressed as(E/E0)4=1+h*Eh.By combining these two formulas,we find that there is a relationship between yield stress σ y and indentation depth h:σy = σy0·(1+h*Hh)f(n)·(1+h*Eh)[0.25-0.54f(n)],where σ y0 is the yield strength associated with the strainhardening exponent n,the true hardness H0 and the true elastic modulus E0.f(n)= 1/2(1-n) is constant,which is only related to n,and h*H and h*E are characteristic lengths for hardness and elastic modulus.The results obtained from inverse analysis show that the elastic-plastic properties of thin films can be uniquely extracted from the solution of this relationship when the indentation size effect has to be taken into account. | Z.S. Ma Y.C. Zhou S.G. Long C.S. Lu | 2012 | Journal of Materials Science & Technology2012，28，7： | 4 |
| 18 | 论人道主义刑罚理论显示文摘英国最近关于死刑的争论正方兴未艾。不知一个谋杀犯何时更容易悔改?是在审判结束后的数周,在绞刑架前为生命画上一个美好的句号;还是在30年后病卧监狱医院之中才幡然醒悟。也不知对死亡的畏惧是否是威慑犯罪所不可或缺的。就本文而言,我无意判断威慑是否具有道德上的合理性。这些问题我可能都不会涉及。本文的主题也非专门谈论死刑,而是讨论有关刑罚的一般理论,即人道主义刑罚观。这种理论在死刑争论中,流行甚广。持此理论的人认为它轻缓仁慈,而我认为他们的想法是极其错误的。这种理论是一种危险的谬论,且会无限地掩盖残忍与不公。重回传统的报应理论不仅对社会有利,而且更重要的是,它也对犯罪人有利。 | C.S.路易斯 罗翔 | 2013 | 暨南学报(哲学社会科学版)2013，35，7： | 4 |
| 19 | 重金属氧化物玻璃——第一部分 制备与性质显示文摘重金属氧化物玻璃是近年发展起来的一类新型玻璃。所谓重金属氧化物,主要指的是氧化铋、氧化铅以及其他在元素周期表中的第五、六周期中具有高原子量的金属氧化物。它们在玻璃组成中的含量一般都超过50%,所以将此类玻璃称作为重金属氧化物(HMO)玻璃。与普通的玻璃相比,最大差异之处在于它们不含有传统观念的玻璃网络形成氧化物,例如SiO2,P2O5,B2O3和GeO2。 | 黄文旵 C.S.雷 D.E.戴 | 1993 | 玻璃与搪瓷1993，21，4： | 3 |
| 20 | Transmission Electron Microscopy Study of the Infrared Brazed High-strength Titanium Alloy显示文摘The transmission electron microscopy was employed to investigate the microstructure of infrared brazed highstrength Ti alloy using the Ti-15Cu-15Ni filler metal. Coarse primary Ti2Ni and transformed β-Ti are observed in the 300 s brazed specimen. Blocky Ti2Ni and eutectoid Ti2Cu intermetallics are disappeared from the joint with increasing the brazing time to 1800 s. Both acicular α-Ti and retained β-Ti dominate the entire brazed joint. | Z.Y. Wu R.K. Shiue C.S. Chang | 2010 | Journal of Materials Science & Technology2010，26，4： | 3 |
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