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| 1 | Association of arterial stiffness with coronary flow reserve in revascularized coronary artery disease patients显示文摘AIM: To investigate the association of arterial wave reflection with coronary flow reserve(CFR) in coronary artery disease(CAD) patients after successful revascularization.METHODS: We assessed 70 patients with angiographically documented CAD who had undergone recent successful revascularization. We measured(1) reactive hyperemia index(RHI) using fingertip peripheral arterial tonometry(RH-PAT Endo-PAT);(2) carotid to femoral pulse wave velocity(PWVc-Complior);(3) augmentation index(AIx), the diastolic area(DAI%) and diastolic reflection area(DRA) of the central aortic pulse wave(Arteriograph);(4) CFR using Doppler echocardiography; and(5) blood levels of lipoprotein-phospholipase A2(LpPLA2).RESULTS: After adjustment for age, sex, blood pressure parameter, lipidemic, diabetic and smoking status, we found that coronary flow reserve was independently related to AIx(b =-0.38, r = 0.009), DAI(b = 0.36, P = 0.014), DRA(b = 0.39, P = 0.005) and RT(b =-0.29,P = 0.026). Additionally, patients with CFR < 2.5 had higher PWVc(11.6 ± 2.3 vs 10.2 ± 1.4 m/s, P = 0.019), SBPc(139.1 ± 17.8 vs 125.2 ± 19.1 mm Hg, P = 0.026), AIx(38.2% ± 14.8% vs 29.4% ± 15.1%, P = 0.011) and lower RHI(1.26 ± 0.28 vs 1.50 ± 0.46, P = 0.012), DAI(44.3% ± 7.9% vs 53.9% ± 6.7%, P = 0.008), DRA(42.2 ± 9.6 vs 51.6 ± 11.4, P = 0.012) and Lp PLA2(268.1 ± 91.9 vs 199.5 ± 78.4 ng/m L, P = 0.002) compared with those with CFR ≥ 2.5. Elevated Lp PLA2 was related with reduced CFR(r =-0.33, P = 0.001), RHI(r =-0.37, P < 0.001) and DRA(r =-0.35, P = 0.001) as well as increased PWVc(r = 0.34, P = 0.012) and AIx(r = 0.34, P = 0.001). CONCLUSION: Abnormal arterial wave reflections are related with impaired coronary flow reserve despite successful revascularization in CAD patients. There is a common inflammatory link between impaired aortic wall properties, endothelial dysfunction and coronary flow impairment in CAD. | Vlassis Tritakis Stavros Tzortzis Ignatios Ikonomidis Kleanthi Dima Georgios Pavlidis Paraskevi Trivilou Ioannis Paraskevaidis Giorgos Katsimaglis John Parissis John Lekakis | 2016 | World Journal of Cardiology2016，8，2： | 4 |
| 2 | Association of Lp-PLA2 with digital reactive hyperemia, coronary flow reserve, carotid atherosclerosis and arterial stiffness in coronary artery disease显示文摘 | Ignatios Ikonomidis Nikolaos N.P. Kadoglou Vlassis Tritakis Ioannis Paraskevaidis Kleanthi Dimas Paraskevi Trivilou Ioannis Papadakis Stavros Tzortzis Helen Triantafyllidi John Parissis Maria Anastasiou-Nana John Lekakis | 2014 | Atherosclerosis2014，，1： | 2 |
| 3 | Attempts to obtain reosseointegration following experiment peri-implantitis in dog显示文摘 | Wetzel AC Vlassis J Caffesse RG | 1999 | Clin Oral Implants Res1999，10，2： | 1 |
| 4 | 柱突然时效导致的多层建筑连续坍塌(1)——简化评估框架显示文摘 | B.A.Izzuddin A.G. Vlassis A.Y.Elghazouli D.A. Nethercot | 2008 | 钢结构2008，，12： | 1 |
| 5 | Perseus: Randomized point-based value iteration for POMDPs显示文摘 | Spaan M T J Vlassis N | 2005 | Journal of Artificial Intelligence Research2005，24，： | 1 |
| 6 | Progressive collapse of multi-storey buildings due to sudden column loss: part I: simplified assessment framework 显示文摘 | Izzuddin B A Vlassis A G Elghazouli A Y | 2008 | Engineering Structures2008，30，5： | 1 |
| 7 | The global K-menas clustering algorithm显示文摘 | Likas A Vlassis M Verbeek J | 2003 | Pattem Recognition2003，36，2： | 1 |
| 8 | Unexpected increase of the CA19-9 tomour meker in patients with endometriosis显示文摘 | Matlliotakis I Panidis D Vlassis G Neonaki M Goumenou A Koumantakis E | 1998 | Eur J Gynecol Oncol1998，19，： | 1 |
| 9 | The global K-means clustering algorithm显示文摘 | Likas A Vlassis M Verbeek J | 2003 | Pattern Recognition2003，36，2： | 1 |
| 10 | The global k-means clustering algorithm 显示文摘 | Likas Vlassis M Verbeek J | 2003 | Pattern Recognition2003，36，2： | 1 |
| 11 | The Global k-Means Clustering Algorithm显示文摘 | Likas A Vlassis N Verbeek J J | | 0，，： | 1 |
| 12 | The global K means clustering algorothm 显示文摘 | Likas A Vlassis M Verbeek J | 2003 | Pattem Recognition2003，36，2： | 1 |
| 13 | The global k-means clustering algorithm显示文摘 | Likas A Vlassis N Verbeek J | 2003 | Pattern Recognition2003，36，2： | 1 |
| 14 | Point-based value iteration for continuous POMDPs显示文摘 | PORTA J M VLASSIS N SPAAN M T J | 2006 | Journal of Mahine Learning Research2006，7，： | 1 |
| 15 | The globalk-means algorithm显示文摘 | N Vlassis J J Verbeek | 2003 | PatternRecognition2003，36，： | 1 |
| 16 | Efficient source adaptivity in independent component analysis显示文摘 | VLASSIS N MOTOMURA Y | 2001 | IEEE Trans on Neural Networks2001，12，3： | 1 |
| 17 | A greedy EM algorithm for Gaussian mixtare learning显示文摘 | Vlassis N Likas A | 2002 | Neural Processing Letters2002，15，1： | 1 |
| 18 | Serum level of the antigens CA125,CA199 and CA153 in patients with endometriosis显示文摘 | POMIDIS D VLASSIS G MATALIONTAKIS J | 1988 | J Endocrinol Invst1988，11，： | 1 |
| 19 | Non-communicative multi-robot coordination in dynamic environments显示文摘 | Kok J R Spaan M T J Vlassis N | 2005 | Robotics andAutonomous Systems2005，50，23： | 1 |
| 20 | The global k-means clustering algorithm显示文摘 | Likas A Vlassis N Verbeek J | | 0，，02： | 1 |
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