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| 1 | 中国政府环境信息公开实施效果评价显示文摘环境信息公开是国际上公认的新一代环境治理手段,也是我国建设'阳光政府'的基本要求.在《环境信息公开办法》实施2 a后,针对31个省级、5个计划单列市和27个省会城市环境保护局落实环境信息公开的制度和行动进行调查分析,通过资料调查、实际公开申请和深入访谈,全面评估政府环境信息公开办法实施的有效性,以期为该办法的进一步完善提供政策建议.结果表明,尽管各级环境保护局公开的环境信息还不够全面、及时、有效,但是政府环境信息公开总体状况已经有了较大进步.目前环境信息公开还存在地区不平衡,而缺乏强制力,信息公开法规相应条款规定模糊,程序和责任不明确是导致环境信息公开不力的重要原因. | 贺桂珍 吕永龙 张磊 Mol ArthurP.J. 冯嫣 | 2011 | 环境科学2011，32，11： | 20 |
| 2 | Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages显示文摘How the innate and adaptive host immune system miscommunicate to worsen COVID-19 immunopathology has not been fully elucidated.Here,we perform single-cell deep-immune profiling of bronchoalveolar lavage(BAL)samples from 5 patients with mild and 26 with critical COVID-19 in comparison to BALs from non-COVID-19 pneumonia and normal lung.We use pseudotime inference to build T-cell and monocyte-to-macrophage trajectories and model gene expression changes along them.In mild COVID-19,CD8^(+)resident-memory(TRM)and CD4^(+)T-helper-17(T_(H17))cells undergo active(presumably antigen-driven)expansion towards the end of the trajectory,and are characterized by good effector functions,while in critical COVID-19 they remain more naïve.Vice versa,CD4^(+)T-cells with T-helper-1 characteristics(TH1-like)and CD8^(+)T-cells expressing exhaustion markers(T_(EX)-like)are enriched halfway their trajectories in mild COVID-19,where they also exhibit good effector functions,while in critical COVID-19 they show evidence of inflammation-associated stress at the end of their trajectories.Monocyte-to-macrophage trajectories show that chronic hyperinflammatory monocytes are enriched in critical COVID-19,while alveolar macrophages,otherwise characterized by anti-inflammatory and antigen-presenting characteristics,are depleted.In critical COVID-19,monocytes contribute to an ATP-purinergic signaling-inflammasome footprint that could enable COVID-19 associated fibrosis and worsen disease-severity.Finally,viral RNA-tracking reveals infected lung epithelial cells,and a significant proportion of neutrophils and macrophages that are involved in viral clearance. | Els Wauters Pierre Van Mol Abhishek Dinkarnath Garg Sander Jansen Yannick Van Herck Lore Vanderbeke Ayse Bassez Bram Boeckx Bert Malengier-Devlies Anna Timmerman Thomas Van Brussel Tina Van Buyten Rogier Schepers Elisabeth Heylen Dieter Dauwe Christophe Dooms Jan Gunst Greet Hermans Philippe Meersseman Dries Testelmans Jonas Yserbyt Sabine Tejpar Walter De Wever Patrick Matthys CONTAGIOUS collaborators Johan Neyts Joost Wauters Junbin Qian Diether Lambrechts | 2021 | Cell Research2021，31，3： | 11 |
| 3 | Evidence of compliance with and effectiveness of guidelines for noninvasive prenatal testing in China:a retrospective study of 189,809 cases显示文摘In China,the medical guidelines recommend performing noninvasive prenatal testing(NIPT)with caution for pregnant women aged 35 years or older.However,the Mother and Child Health Care Law suggests that all primiparous women whose age is older than 35 years undergo prenatal diagnosis.These two inconsistent suggestions/recommendations have made obstetricians confused about whether to offer NIPT to these older pregnant women.To face this issue and find out the solution we performed a retrospective study of 189,809 NIPT samples collected from 28 provincial-leveled administrative units in China.Of 1,564 women with high-risk pregnancies who underwent NIPT,459(29.3%)did not participate in follow-up.The compound sensitivity and specificity of NIPT for trisomies 21,18 and 13 detection was 99.1%(95%CI,98.0%–99.6%)and 99.9%(95%CI,98.8%–99.9%),respectively.In secundiparous women,NIPT showed high sensitivity and specificity similar to that in primiparous women.The observed risk for trisomies 21 and 18 significantly increased when the maternal age was 39 and older.After the publication of the current NIPT policy,the follow-up rate at our center was 97.9%;however,a large number of women are not in maternal and infant care networks nationwide,and that makes the follow-up rate outside our center relatively low.Our study shows that to balance the prevention of major aneuploidies and the limited resources for prenatal diagnosis,the cut-off age of 35 for invasive prenatal diagnosis might be unnecessary.Although the NIPT guidelines are well written,how to practice it effectively,especially in less industrialized areas,is worth discussing. | Chan Tian Tao Deng Xiuhuang Zhu Chen Gong Yangyu Zhao Yuan Wei Rong Li Xiufeng Xu Miaonan He Zhiwei Zhang Jing Cheng Mol BenWillem Jie Qiao | 2020 | Science China(Life Sciences)2020，63，3： | 10 |
| 4 | An implementation assessment of China's Environmental Information Disclosure Decree显示文摘China's 2007 Open Government Information Regulations is widely considered as a milestone in the country's information policy history and is praised as a'sunshine program'.The Environmental Information Disclosure Decree was the first to operationalize these general regulations into a sectoral information disclosure system on environment.This study assessed the implementation of the environmental information disclosure system about six months after the Decree took eect on May 1,2008.Through reviewing the websites of all 31 provincial Environmental Protection Bureaus and the Ministry of Environmental Protection,conducting an experiment with actual information disclosure request,and through interviews with all provincial Environmental Protection Bureaus,this article concluded that the implementation of the environmental information disclosure system still falls short.Future improvements should focus on further publicity of the regulations and decree to enhance public participation,the establishment of an independent evaluation and supervision system for information disclosure,the exchange of experiences and best practices among provincial Environmental Protection Bureaus,and on strengthening the legal status of environmental information disclosure. | Lei Zhang Arthur E J Mol Guizhen He Yonglong Lu | 2010 | Journal of Environmental Sciences2010，22，10： | 9 |
| 5 | 中国的低碳转型与生态现代化显示文摘生态现代化理论探讨了国家在社会体制、经济发展和社会思想意识形态等方面的生态化转向,为政府、企业以及非政府团体和个人在面对环境问题时应该如何做出调整提供了一种新的思路。本文综述了生态现代化理论的核心思想和基本要素,并探讨了该理论发展过程中的主要争论。考虑目前国内经济的发展动态和发展低碳经济的迫切需求,这一理论对推动我国经济的低碳转型有着重要的借鉴意义。尤其是该理论发展过程中关于生产与消费的讨论,更为探讨发展低碳经济的核心定位等问题提供了参考。结合生态现代化观点和争论,本文提出我国经济的低碳转型,需要从尤其强调生产端导向的碳减排向同时兼顾上下游并重视消费者作用的战略思路转变;经济变革同时强调制度变革,转变行政命令控制为主的规制格局,促进多角色的参与;作为生产的微观主体,企业需强调以保护生态为己任的机构和管理改革,长远的发展更需要构建一种生产者与消费者之间有效衔接的消费导向战略。这些转变都将有利地推动中国经济的低碳现代化。 | 刘文玲 王灿 Spaargaren Gert Mol Arthur P J | 2012 | 中国人口·资源与环境2012，22，9： | 8 |
| 6 | Payment for Environmental Services:The Sloping Land Conversion Program in Ningxia Autonomous Region of China显示文摘自从 2002,中国的泼出陆地变换节目被实现了。它试图达到生态的恢复和贫穷缓和的目标,由陡峭地退休泼出从庄稼生产和释放剩余的土地为离开农场活动的农业劳动。给被倒进它的巨大的投资,并且它的生态、社会的影响,这个开始政府的节目吸引了重要学术注意并且触发了争论的洪水。自从 2004,争论专注于节目的可持续性。尽管目标完了在一些省完成了,在津贴停止以后,担心仍然关于农民的生计出现了。现在的论文在 Ningxia 自治区域分析泼出的陆地变换节目的实现,与为农民的持续参予和离开农场经济活动的发展的要求的社会大写字的一个焦点。 | Lei Zhang Qin Tu Arthur P. J. Mol | 2008 | China & World Economy2008，16，2： | 8 |
| 7 | The No Apical Meristem Gene of Petunia Is Required for Pattern Formation in Embryos and Flowers and Is Expressed at Meristem and Primordia Boundaries显示文摘 | Erik Souer Adèle van Houwelingen Daisy Kloos Jos Mol Ronald Koes | 1996 | Cell1996，，2： | 5 |
| 8 | 早发性先兆子痫,迟发性先兆子痫和妊娠高血压后的心血管疾病危险因素显示文摘研究表明,有妊娠高血压病史的妇女心血管疾病(cardiovasculardisease,CVD)终生风险增加。这种风险与妊娠相关高血压疾病的严重程度及发病孕周有关。然而,cVD危险因素的差异是否在产后心血管筛查时就已经存在尚不清楚。研究人员将妊娠期高血压疾病患者分为3个亚组,分析CVD危险因素的产后差异。 | 刘莉 叶鹏 Veerbeek JH Hermes W Breimer AY van Rijn BB Koenen SV Mol BW Franx A de Groot CJ Koster MP | 2015 | 中华高血压杂志2015，23，2： | 5 |
| 9 | Emerging pollutants in the environment:A challenge for water resource management显示文摘A significant number of emerging pollutants(EPs)resulting from point and diffuse pollution is present in the aquatic environment.These are chemicals that are not commonly monitored but have the potential to enter the environment and cause adverse ecological and human health effects.According to the NORMAN network,at least 700 substances categorized into 20 classes,have been identified in the European aquatic environment.In light of their potential impact action is urgently required.In this study,we present a concept that shows the current state of art and challenges for monitoring programs,fate and risk assessment tools and requirements for policies with respect to emerging pollutants as a base for sustainable water resource management.Currently,methods for sampling and analysis are not harmonized,being typically focused on certain EP classes.For a number of known highly hazardous EPs detection limits are too high to allow proper risk assessment.For other EPs such as microplastics method development is in its infancy.Advanced ultra-sensitive instrumental techniques should be used for quantitative determination of prioritized EPs in water,suspended matter,soil and biota.Data on EPs'and their metabolites'properties that determine their fate in the environment are often not available.National surveys on water quality often use different parameters for water quality assessment and often do not include EPs.A harmonized monitoring of surface and groundwater is not yet achieved and urgently required.Specific component integrated into models assessing the fate of EPs in a multi compartment environmental approach are missing and must be developed.The main goal of risk assessment is the overall protection of ecological communities in the aquatic environment and human health.New methods for assessing the cumulative risks from combined exposures to several stressors,including mixtures of EPs in a multi-scale approach are required.A combination of regulations and management measures with respect to use/emissions of EPs into the environment,as well as to their occurrence in the environment are fundamental to reach an efficient water resource management. | Violette Geissen Hans Mol Erwin Klumpp Günter Umlauf Marti Nadal Martine van der Ploeg Sjoerd E.A.T.M.van de Zee Coen J.Ritsema | 2015 | International Soil and Water Conservation Research2015，3，1： | 3 |
| 10 | Towards Cr(VI)-free anodization of aluminum alloys for aerospace adhesive bonding applications: A review显示文摘 | Shoshan T. Abrahami John M.M. de Kok Herman Terryn Johannes M.C. Mol | 2017 | Frontiers of Chemical Science and Engineering2017，11，3： | 3 |
| 11 | Tuberosity malposition and migration: Reasons for poor outcomes after hemiarthroplasty for displaced fractures of the proximal humerus显示文摘 | P Boileau S.G Krishnan L Tinsi G Walch J.S Coste D Molé | 2002 | Journal of Shoulder and Elbow Surgery2002，，5： | 2 |
| 12 | 地表水和污水系统一体化调度平台的研发显示文摘详细描述了荷兰Hoeksche Waard的地表水和污水系统一体化调度系统平台(荷兰语中简称为ISA项目)示范系统的研发。该项目开发了Hoeksche Waard区域的地表水和污水一体化自动控制系统(Control-NEXT),项目涉及5个市政区和1个水务局。该项目目标为通过提高不同水务管理机构之间的协作来改善地表水水质。 | Mol B van Loenen A 耿为民 | 2013 | 中国给水排水2013，29，21： | 2 |
| 13 | Metallographic Methods for Revealing the Multiphase Microstructure of TRIP-Assisted Steels显示文摘 | E. Girault P. Jacques Ph. Harlet K. Mols J. Van Humbeeck E. Aernoudt F. Delannay | 1998 | Materials Characterization1998，，2： | 2 |
| 14 | The chalcone synthase multigene family of Petunia hybrida (V30): differential, light-regulated expression during flower development and UV light induction显示文摘 | Ronald E. Koes Cornelis E. Spelt Joseph N. M. Mol | 1989 | Plant Molecular Biology1989，，2： | 2 |
| 15 | Salpingotomy versus salpingectomy in women with tubal pregnancy (ESEP study): an open-label, multicentre, randomised controlled trial显示文摘 | Femke Mol Norah M van Mello Annika Strandell Karin Strandell Davor Jurkovic Jackie Ross Kurt T Barnhart Tamer M Yalcinkaya Harold R Verhoeve Giuseppe C M Graziosi Carolien A M Koks Ingmar Klinte Lars Hogstr?m Ineke C A H Janssen Harry Kragt Annemieke Hoek | 2014 | The Lancet2014，，： | 2 |
| 16 | Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression显示文摘 | Motoyuki Otsuka Qing Jing Philippe Georgel Liguo New Jianming Chen Johann Mols Young Jun Kang Zhengfan Jiang Xin Du Ryan Cook Subash C. Das Asit K. Pattnaik Bruce Beutler Jiahuai Han | 2007 | Immunity2007，，1： | 2 |
| 17 | ENVIRONMENTAL INFORMATION DISCLOSURE IN CHINA: IN THE ERA OF INFORMATIZATION AND BIG DATA显示文摘过去的十年看见了在中国在环境信息揭发的领域里取得的显著进步。当时全面机构的变化和政府的动机 / 心甘情愿开创信息是重要条件,有革命信息和通讯的瓷器相遇工艺(ICT ) 前进和很快新兴的大数据快速从一个信息改变了中国差的环境到信息建筑群环境。当在被认出在的那些开车 / 限制上集中的大多数以前的研究建立了参考统治框架时,在 ICT 和新兴的大数据的最近的前进提出了新挑战,机会和研究问题。当增加揭发在环境统治成为了新比赛 changer 的信息时,中国不得不也在新授权技术的信息环境应付风险和陷井。这篇文章在中国和他们的实现有效性关于环境信息揭发在立法 / 规定 / 政策上更新了以前的研究,并且对瓷器最近的 informatization 进步和新兴的大数据给予了特殊注意。信息揭发被当作包括数据 / 信息产生 / 收集,揭发,通讯的功能的小径,和直接 / 间接的影响的一个过程。在环境信息揭发的变化应该在总的来说在中国改变环境统治和 informatization 的更宽广的上下文被理解。作为一把双重的剑理解 ICT 和信息揭发是重要的。揭发以及收集和报导费用,指向的透明性的问题,和非计划中的使用的风险的标准、真实、仪器的好处应该战略上被考虑。当最大化好处时,原则和指南需要被发展避免陷井。 | ZHANG Lei Arthur P. J. Mol YANG Shuai | 2017 | Frontiers of Law in China-Selected Publications from Chinese Universities2017，12，1： | 2 |
| 18 | An iterative thresholding algorithm for linear inverse problems with a sparsity constraint 显示文摘 | DAUBECHIES I DEFRIESE M de MOL C | 2004 | Communications in Pure and Applied Mathematics2004，57，11： | 1 |
| 19 | The role of an- timullerian hormone in prediction of outcome after IVF: comparison with the antral follicle count显示文摘 | Broer SL Mol BW Hendriks D | 2009 | Fertil Ster- il2009，91，3： | 1 |
| 20 | Randomised comparisons of medical tests: sometimes invalid, not always efficient显示文摘 | Bossuyt PM Lijmer JG Mol BW | 2000 | Lancet2000，356，9244： | 1 |
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