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	题名	作者	年代	出处	被引量
1	Temporomandibular joint damage in K/BxN arthritic mice显示文摘Rheumatoid arthritis(RA) is an autoimmune disease affecting 1% of the world population and is characterized by chronic inflammation of the joints sometimes accompanied by extra-articular manifestations. K/Bx N mice, originally described in 1996 as a model of polyarthritis, exhibit knee joint alterations. The aim of this study was to describe temporomandibular joint(TMJ)inflammation and damage in these mice. We used relevant imaging modalities, such as micro-magnetic resonance imaging(μMRI)and micro-computed tomography(μCT), as well as histology and immunofluorescence techniques to detect TMJ alterations in this mouse model. Histology and immunofluorescence for Col-I, Col-II, and aggrecan showed cartilage damage in the TMJ of K/Bx N animals, which was also evidenced by μCT but was less pronounced than that seen in the knee joints. μMRI observations suggested an increased volume of the upper articular cavity, an indicator of an inflammatory process. Fibroblast-like synoviocytes(FLSs)isolated from the TMJ of K/Bx N mice secreted inflammatory cytokines(IL-6 and IL-1β) and expressed degradative mediators such as matrix metalloproteinases(MMPs). K/Bx N mice represent an attractive model for describing and investigating spontaneous damage to the TMJ, a painful disorder in humans with an etiology that is still poorly understood.	Sabine Kuchler-Bopp Alexandre Mariotte Marion Strub Chrystelle Po Aurore De Cauwer Georg Schulz Xavier Van Bellinghen Florence Fioretti Francois Clauss Philippe Georgel Nadia Benkirane-Jessel Fabien Bornert	2020	International Journal of Oral Science2020，12，1：	6
2	Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression显示文摘	Motoyuki Otsuka Qing Jing Philippe Georgel Liguo New Jianming Chen Johann Mols Young Jun Kang Zhengfan Jiang Xin Du Ryan Cook Subash C. Das Asit K. Pattnaik Bruce Beutler Jiahuai Han	2007	Immunity2007，，1：	2
3	Genetic and epigenetic regulations of prostate cancer by genistein显示文摘	Molinie B Georgel P	2009	Drug news & perspectives2009，22，6：	1
4	Photoinduced Electron-Transfer Processes in Fullerene-Based Donor-Acceptor Systems显示文摘	K George Thomas Manapurathu V Georgel	2005	Helvetica Chimica Acta2005，88，6：	1
5	Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection显示文摘	Tabeta K Georgel P Janssen E	2004	Proc Natl Acad Sci USA2004，101，10：	1
6	To the 30-nm chromatin fiber and beyond显示文摘	Adkins NL Watts M Georgel PT	2004	Biochim Biophys Acta2004，1677，：	1
7	Identification of Lps2 as a key transducer of MyD88-independent T1R signalling显示文摘	HOEBE K DU X Georgel P	2003	Nature2003，424，6950：	1
8	Identification of Lps2 as a key transducer of MyD88-independent TIR signalling 显示文摘	Hoebe K Du X Georgel P	2003	Nature2003，424，6950：	1
9	Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection 显示文摘	Tabeta K Georgel P Janssen E	2004	Proc Natl Acad Sci USA2004，101，10：	1
10	Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24and miR93expression显示文摘	OTSUKA M JING Q GEORGEL P	2007	Immunity2007，27，1：	1
11	Identification of LPS2 as a key transducer o f MyD88independent TIR signaling显示文摘	Hoebe K Du X Georgel P	2003	Nature2003，424，：	1
12	The Optimization of The Internal and External Reporting in Financial Accounting: Adopting Xbrl International Standard 显示文摘	Vasile Florescu Ctlin Georgel Tudor	2009	Annales Universitatis Apulensis Series Oeconomica2009，11，1：	1
13	Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection显示文摘	Tabeta K Georgel P Janssen E	2004	Proc Natl Acad Sci U S A2004，101，10：	1
14	Drosophila immune de?ciency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis显示文摘	Georgel P Naitza S Kappler C		0，，04：	1
15	Vesicular stomatitis virus gly- eoprotein G actives a specific antiviral Toll-like receptor 4-depend- ent pathway显示文摘	Georgel P Jiang ZF Kunz S	2007	Virology2007，362，2：	1
16	Identification of Lps2 as a key transducer of MyD88-independent TIR signalling 显示文摘	Hoebe K Du X Georgel P	2003	Na- ture2003，424，：	1
17	TLR signaling pathways: opportunities for activation and blockade in pursuit of therapy 显示文摘	Hoebe K Jiang Z Georgel P	2006	Curr Pharm Des2006，12，32：	1
18	Robust multi - item newsboy model with a budget constraint显示文摘	Vairaktarakis	2000	International journal of produc tion economics2000，66，：	1
19	Identification of Lps2 as a key transducer of MyD88-independentTIR signaling显示文摘	Hoebe K Du X Georgel P	2003	Nature2003，424，6950：	1
20	Diagnosis of suspected Alzheimer's disease is improved by automated analysis of regional cerebral blood flow显示文摘	Tang BNT Minoshima S Georgel J	2004	Eur J Nucl Med Mol Imaging2004，31，：	1

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