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| 1 | 青藏高原东部及周边现时地壳运动显示文摘通过1991—2001年期间在青藏高原东部及周边地区的GPS测量,获得该地区不同参考框架下的地壳运动速度场,其测量的速度精度高于2mm/yr。印度板块与华北地块之间的地壳形变分为喜马拉雅及高原南部、高原中部(拉萨—格尔木)和高原北部(格尔木—金塔)三部分,它们分别吸收了印度板块与欧亚板块汇聚速率的43%、24%和32%。在欧亚框架下和相对于成都,印度板块和华南地块之间存在着以东喜马拉雅构造结为轴心的顺时针巨型涡旋构造———滇藏涡旋构造,运动速度分别为26~6mm/yr和24~7mm/yr,总体上从北东方向转变为南东和南西方向,有别于青藏高原中部的北东方向。滇藏涡旋和东喜马拉雅构造结的形成与南迦巴瓦 阿萨姆'犄角'的楔入作用有关。 | 刘宇平 陈智梁 唐文清 赵济湘 张选阳 张清志 Robert W. King Burrcel C. Burchfiel Leigh H. Royden | 2003 | 沉积与特提斯地质2003，23，4： | 14 |
| 2 | 蚯蚓(Eiseniafetida)细胞色素P450及抗氧化酶系对环境浓度苯并(a)芘的响应显示文摘以赤子爱胜蚓(Eisenia fetida)为供试生物,草甸棕壤为供试土壤,以蚯蚓微粒体细胞色素P450含量、抗氧化酶系以及谷胱甘肽转移酶活性为指标,进行了土壤中苯并(a)芘[B(a)P]暴露与酶活性的量-效关系研究。结果表明,在接近沈抚灌区实地污染状况B(a)P(0.1~2.0mg.kg-1)暴露下,第1、3、7以及第14d取样时,P450和SOD有较好的响应:SOD在第1、3d显著升高,而在第7、14d时降低;P450总体表现为低浓度B(a)P诱导下降低,高浓度下升高的趋势。CAT、POD以及GST的敏感性相对较差。比照其他4个指标,蚯蚓P450的敏感性更为优异,具有较好的应用前景。指标敏感性总体表现为:P450>SOD>CAT/POD>GST。 | 王磊 宋玉芳 张薇 陈朗 David Freestone M Leigh Ackland | 2009 | 农业环境科学学报2009，28，2： | 12 |
| 3 | 岩粉施加对水稻生态系统植硅体碳的增汇作用显示文摘植硅体态碳(phytolith-occluded organic carbon,Phyt OC),在植硅体的坚硬外壳“保护”下,可以长时间地保存在一些土壤和沉积物中,作为一种相对稳定和“安全”的长期有效的生物固碳机制,在全球农业生态系统碳汇和气候变化中有着重要的作用,目前已经引起了越来越多科学家的关注.如何加强和提高农业生态系统中植硅体碳汇潜力是目前研究的热点和重点.
Li等人研究发现水稻植株植硅体态碳产生量,不仅与其植硅体占干物质的量有关,也与植硅体封存有机碳的效率有关,可以通过硅营养调控机制来增加其植硅体的积累量和植硅体态碳占干物质的量来增加农业土壤和植物中植硅体态碳汇的潜力. | 郭凤山 宋照亮 Leigh Sullivan 王海龙 刘学炎 王旭东 李自民 赵玉营 | 2015 | 科学通报2015，60，10： | 10 |
| 4 | 植物CytP450和抗氧化酶对土壤菲、芘暴露的生态毒理响应显示文摘以玉米(ZeamaysL.)为供试植物,草甸棕壤为供试土壤,以微粒体细胞色素P450含量、超氧化物歧化酶(SOD)、过氧化氢酶(CAT)和过氧化物酶(POD)活性为指标,进行了土壤菲、芘暴露的生态毒理响应研究.结果表明,菲、芘暴露均能引起植物代谢解毒和抗氧化防御系统的胁迫响应,不同程度引发植物代谢解毒及抗氧化能力的改变.P450酶活性与低浓度菲、芘单一暴露浓度具有相关性(r=0.834,p<0.01),与菲、芘复合暴露浓度负相关,说明菲、芘复合暴露导致代谢解毒能力下降,对植物的代谢解毒具有协同毒性效应;SOD酶活性与菲、芘单一暴露浓度负相关,CAT酶活性与菲、芘单一暴露浓度正相关,POD酶活性与菲的水溶解度正相关,而与芘的总浓度负相关.SOD、CAT和POD酶活性与菲、芘复合暴露浓度均呈正相关,说明菲、芘复合暴露导致氧化损伤程度减弱,对植物的氧化损伤具有拮抗作用. | 宋玉芳 王磊 李昕馨 张薇 陈朗 Freestone David 吉普辉 Ackland M Leigh | 2009 | 环境科学学报2009，29，2： | 9 |
| 5 | The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide显示文摘 | Joseph F. Perz Gregory L. Armstrong Leigh A. Farrington Yvan J.F. Hutin Beth P. Bell | 2006 | Journal of Hepatology2006，，4： | 7 |
| 6 | Acanthomorph Biostratigraphic Succession of the Ediacaran Doushantuo Formation in the East Yangtze Gorges,South China显示文摘大 acanthomorphic acritarchs 在华南在几个地区在 Ediacaran Doushantuo 形成的燧石被发现了,包括湖北省的东方 Yangtze 峡,贵州省的 Weng'an 区域,并且在其它地方。然而,他们为 biostratigraphic 分和 Ediacaran 继任的关联的潜力被外形控制, taphonomic 偏爱,和分类问题限制。在 Yangtze 峡, Doushantuo 形成通常被细分进四个 lithologic 成员。在 Weng'an 区域,然而, Doushantuo 形成包括就 mid-Doushantuo erosional 表面分开的更低、上面的部分。在在 Zhangcunping 节的 Yangtze 峡, Doushantuo 继任在 Weng'an 类似于那。到目前为止,在 Yangtze 之间的关联塞满并且 Weng'an 区域,并且在其它地方是争论的一个问题。解决争论,我们在 Yangtze 峡区域选择了八节并且全身地取样了 Doushantuo 形成的燧石小瘤,特别地集中于上面的 Doushantuo 形成。我们的数据证实在第二和第三个成员独立出现的二个不同集合,它被一次否定 13C 旅行(EN2 ) 分开。更低的集合被 Tianzhushania 和大 acanthomorphic acritarchs 的一间多样的套房描绘。上面的集合与更低的集合被区分开来,由(1 ) Tianzhushania 的缺席;(2 ) 出现丰富, 100150 m,光滑墙的球形的微化石;(3 ) 包括种类在这个成员从第二个成员和新形式延长的高度多样的 acanthomorphic acritarchs 的出现;(4 ) 原生生物的未命名的新形式的出现;并且(5 ) 管状的微化石 Sinocyclocylicus guizhouensis 的出现。因为统治 Tianzhushania 的集合不是在澳大利亚的现在,看起来仅仅上面的 acanthomorph 集合是在场的,因此,更低的 Doushantuo acanthomorph 集合在澳大利亚失踪。 | YIN Chongyu LIU Pengju Stanley M. AWRAMIK CHEN Shouming TANG Feng GAO Linzhi WANG Ziqiang Leigh A. RIEDMAN | 2011 | Acta Geologica Sinica(English Edition)2011，85，2： | 6 |
| 7 | Microbial communities biostimulated by ethanol during uranium (VI) bioremediation in contaminated sediment as shown by stable isotope probing显示文摘(啜) 稳定的同位素探查被用来识别乙醇增加在包含在 US 能源部橡树理兹地点从 bioremediation 测试地区收集的二沉积的缩影刺激的微生物, TN,美国。一件样品是高度有乙醇的 bioreduced 当另外一个少些被减少时。有各自的沉积的缩影与标记乙醇并且为啜为 7 孵化了天的 13C 被修改。乙醇很快在伴有硝酸盐和硫酸盐的减小的 24 h 以内被变换成醋酸盐。醋酸盐的累积在远处坚持了 7 d 时期。水的 U 没由于 U 的解吸附作用与减少的沉积在缩影衰退,但是连续地在少些减少的样品衰退。微生物引起的生长和伴随物 < 啜 class= “ a-plus-plus ” > 13 C-DNA 生产被检测乙醇是否是精疲力尽的,丰富的醋酸盐在两个缩影积累了。这在少些减少的样品与 U (VI ) 减小与一致。< 啜 class= “ a-plus-plus ” > 13 从乙醇发源的 C 最终为生长被利用,直接或间接地,由在 7 天孵化以内的主导的微生物引起的社区成员。微生物引起的社区由包括 Desulfovibrio, Sphingomonas, Ferribacterium, Rhodanobacter, Geothrix, Thiobacillus 和其它减少细菌的已知的 denitrifiers,减少硫酸盐的细菌和铁(III ) 主要组成,包括减少细菌 Acidovorax, Anaeromyxobacter, Desulfovibrio, Geobacter 和 Desulfosporosinus 的已知的 U (VI ) 。调查结果建议那乙醇 biostimulates 由首先为硝酸盐,硫酸盐,铁( III )和 U ( VI )用作一个电子施主减少微生物引起的社区的 U ( VI )减小,并且然后为微生物引起的生长为 U ( VI )减小和碳来源作为电子施主工作的醋酸盐。 | Mary Beth LEIGH Wei-Min WU Erick CARDENAS Ondrej UHLIK Sue CARROLL Terry GENTRY Terence L. MARSH Jizhong ZHOU Philip JARDINE Craig S. CRIDDLE James M. TIEDJE | 2015 | Frontiers of Environmental Science & Engineering2015，9，3： | 5 |
| 8 | Enhancing phytolith carbon sequestration in rice ecosystems through basalt powder amendment显示文摘由于大气的公司的快速的增加的全球温暖 < 潜水艇 class= “ a-plus-plus ” > 2 排放显著地正在影响世界经济和人的活动。在 phytoliths 的碳隐遁在陆上的生态系统被认为是高度稳定的碳水池机制减轻气候变化。然而,植物的反应到外部硅修正案的堵塞 phytolith 的碳(PhytOC ) 仍然保持不清楚。在这研究,我们调查了暗岩粉末(BP ) 的效果在米饭(Oryza sativa ) 的 phytolith 碳隐遁上的改正,一个 high-PhytOC 蓄电池。结果证明在米饭的 phytolith 和 PhytOC 的内容与 BP 改正增加了。在不同米饭植物部分的 PhytOC 生产流动更加变化了(0.0050.041 ? Mg 公司 < 潜水艇 class= “ a-plus-plus ” > 2 哈 < 啜 class= “ a-plus-plus ” > 1 一 < 啜 class= “ a-plus-plus ” > 有在鞘的最高的流动的 1 ), 。BP 改正能显著地在 150 在农田提高 phytolith 碳隐遁的流动 ?% 。如果 1.55 的全球米饭耕作 ?? 慣敲? | Fengshan Guo Zhaoliang Song Leigh Sullivan Hailong Wang Xueyan Liu Xudong Wang Zimin Li Yuying Zhao | 2015 | Science Bulletin2015，60，6： | 4 |
| 9 | Canadian children’s and youth’s adherence to the 24-h movement guidelines during the COVID-19 pandemic: A decision tree analysis显示文摘Purpose:The purpose of this study was to use decision tree modeling to generate profiles of children and youth who were more and less likely to meet the Canadian 24-h movement guidelines during the coronavirus disease-2019(COVID-19)outbreak.Methods:Data for this study were from a nationally representative sample of 1472 Canadian parents(Meanage=45.12,SD=7.55)of children(511 years old)or youth(1217 years old).Data were collected in April 2020 via an online survey.Survey items assessed demographic,behavioral,social,micro-environmental,and macro-environmental characteristics.Four decision trees of adherence and non-adherence to all movement recommendations combined and each individual movement recommendation(physical activity(PA),screen time,and sleep)were generated.Results:Results revealed specific combinations of adherence and non-adherence characteristics.Characteristics associated with adherence to the recommendation(s)included high parental perceived capability to restrict screen time,annual household income ofCAD 100,000,increases in children’s and youth’s outdoor PA/sport since the COVID-19 outbreak began,being a boy,having parents younger than 43 years old,and small increases in children’s and youth’s sleep duration since the COVID-19 outbreak began.Characteristics associated with non-adherence to the recommendation(s)included low parental perceived capability to restrict screen time,youth aged 1217 years,decreases in children’s and youth’s outdoor PA/sport since the COVID-19 outbreak began,primary residences located in all provinces except Quebec,low parental perceived capability to support children’s and youth’s sleep and PA,and annual household income ofCAD 99,999.Conclusion:Our results show that specific characteristics interact to contribute to(non)adherence to the movement behavior recommendations.Results highlight the importance of targeting parents’perceived capability for the promotion of children’s and youth’s movement behaviors during challenging times of the COVID-19 pandemic,paying particular attention to enhancing parental perceived capability to restrict screen time. | Michelle D.Guerrero Leigh M.Vanderloo Ryan E.Rhodes Guy Faulkner Sarah A.Moore Mark S.Tremblay | 2020 | Journal of Sport and Health Science2020，9，4： | 4 |
| 10 | Whole-body heat exposure induces membrane changes in spermatozoa from the cauda epididymidis of laboratory mice显示文摘这研究被执行决定到热环境温度的暴露是否在精子质量上有直接、有害效果。为这,实验室老鼠的 epididymal 精子上的整个身体的热暴露的效果被调查。C57BL/6 鼠标(n = 7 ) 是在在 37 掳 C 鈥 ? 的一个小气候房间的 housed 为 8 h 的 8 掳 C 每为三连续的天的天,当时控制鼠标(n = 7 ) 在 23 掳 C 被保留鈥 ? 4 掳 C。尾 epididymal 精子被获得在最后热处理以后的 16 h。结果证明精子号码在二个组是类似的(P = 0.23 ) ,但是在热处理以后,在能动精子的百分比的重要减小是在场的(P < 0.0001 ) 。精子的膜变化被与结合的藻红朊(PE ) 染色 Annexin V 调查,它检测 phosphotidylserine 的 exteriorization 从对精子血浆膜,和 7-aminoactinomycin D (7-AAD ) 的外部传单内部,当血浆膜被损坏时,它绑在精子原子核。显示出与 Annexin V 鈥揚E 或 7-AAD 或两个的积极染色的精子的百分比,显著地更高(P < 0.05 ) 在暴露热的老鼠与控制相比。这些结果显示出那整个身体的热暴露到 8 掳 C 导致的 37 掳 C 鈥 ? 膜在老鼠的 epididymal 精子变化,它可以导致 apoptosis。 | Harsha Wechalekar Brian P. Setchell Eleanor J. Peirce Mario Ricci Chris Leigh William G. Breed | 2010 | Asian Journal of Andrology2010，12，4： | 4 |
| 11 | “Scarless” (in the Neck) Endoscopic Thyroidectomy (SET): An Evidence-based Review of Published Techniques显示文摘 | Charles T. K. Tan W. K. Cheah Leigh Delbridge | 2008 | World Journal of Surgery2008，，7： | 3 |
| 12 | Macrophage secretory products induce an inflammatory phenotype in hepatocytes显示文摘AIM:To investigate the influence of macrophages on hepatocyte phenotype and function.METHODS:Macrophages were differentiated from THP-1 monocytes via phorbol myristate acetate stimulation and the effects of monocyte or macrophageconditioned medium on HepG2 mRNA and protein expression determined.The in vivo relevance of these findings was confirmed using liver biopsies from 147 patients with hepatitis C virus(HCV)infection.RESULTS:Conditioned media from macrophages,but not monocytes,induced a transient morphological change in hepatocytes associated with upregulation of vimentin(7.8±2.5-fold,P=0.045)and transforming growth factor(TGF)-β1(2.6±0.2-fold,P<0.001)and downregulation of epithelial cadherin(1.7±0.02-fold,P=0.017)mRNA expression.Microarray analysis revealed significant upregulation of lipocalin-2(17-fold,P <0.001)and pathways associated with inflammation,and substantial downregulation of pathways related to hepatocyte function.In patients with chronic HCV,realtime polymerase chain reaction and immunohistochemistry confirmed an increase in lipocalin-2 mRNA(F0 1.0 ±0.3,F1 2.2±0.2,F2 3.0±9.3,F3/4 4.0±0.8,P= 0.003)and protein expression(F1 1.0±0.5,F2 1.3± 0.4,F3/4 3.6±0.4,P=0.014)with increasing liver injury.High performance liquid chromatography-tandem mass spectrometry analysis identified elevated levels of matrix metalloproteinase(MMP)-9 in macrophageconditioned medium,and a chemical inhibitor of MMP-9 attenuated the change in morphology and mRNA expression of TGF-β1(2.9±0.2 vs 1.04±0.1,P<0.001) in macrophage-conditioned media treated HepG2 cells.In patients with chronic HCV infection,hepatic mRNA expression of CD163(F0 1.0±0.2,F1/2 2.8±0.3,F3/4 5.3±1.0,P=0.001)and MMP-9(F0 1.0±0.4,F1/2 2.8±0.3,F3/4 4.1±0.8,P=0.011)was significantly associated with increasing stage of fibrosis.CONCLUSION:Secreted macrophage products alter the phenotype and function of hepatocytes,with increased expression of inflammatory mediators,suggesting that hepatocytes actively participate in liver injury. | Michelle Melino Victoria L Gadd Gene V Walker Richard Skoien Helen D Barrie Dinesh Jothimani Leigh Horsfall Alun Jones Matthew J Sweet Gethin P Thomas Andrew D Clouston Julie R Jonsson Elizabeth E Powell | 2012 | World Journal of Gastroenterology2012，18，15： | 3 |
| 13 | Genetic and genomic resources for Rubus breeding:a roadmap for the future显示文摘Rubus fruits are high-value crops that are sought after by consumers for their flavor,visual appeal,and health benefits.To meet this demand,production of red and black raspberries(R.idaeus L.and R.occidentalis L.),blackberries(R.subgenus Rubus),and hybrids,such as Boysenberry and marionberry,is growing worldwide.Rubus breeding programmes are continually striving to improve flavor,texture,machine harvestability,and yield,provide pest and disease resistance,improve storage and processing properties,and optimize fruits and plants for different production and harvest systems.Breeders face numerous challenges,such as polyploidy,the lack of genetic diversity in many of the elite cultivars,and until recently,the relative shortage of genetic and genomic resources available for Rubus.This review will highlight the development of continually improving genetic maps,the identification of Quantitative Trait Loci(QTL)s controlling key traits,draft genomes for red and black raspberry,and efforts to improve gene models.The development of genetic maps and markers,the molecular characterization of wild species and germplasm,and highthroughput genotyping platforms will expedite breeding of improved cultivars.Fully sequenced genomes and accurate gene models facilitate identification of genes underlying traits of interest and enable gene editing technologies such as CRISPR/Cas9. | Toshi M.Foster Nahla V.Bassil Michael Dossett Margaret Leigh Worthington Julie Graham | 2019 | Horticulture Research2019，6，1： | 2 |
| 14 | Taste and mouth-feel properties of different types of tannin-like polyphenolic compounds and anthocyanins in wine显示文摘 | Stéphane Vidal Leigh Francis Ann Noble Mariola Kwiatkowski Véronique Cheynier Elizabeth Waters | 2003 | Analytica Chimica Acta2003，，1： | 2 |
| 15 | Nitrate accumlation by wheat(Triticum aestivum)in relation to growth and tissue nitrogen concentration显示文摘 | Zhen R G Leigh R A | 1990 | Plant and Soil1990，124，： | 2 |
| 16 | 机器人的“道德经”显示文摘机器人将在我们的生活中扮演重要角色,现在是它们该学习如何遵守伦理道德规则“为人处世”的时候了。 | 迈克尔·安德森(Michael Anderson) 苏珊·利·安德森(Susan Leigh Anderson) 冯帅(翻译) 孙增圻(审校) | 2010 | 环球科学2010，，11： | 2 |
| 17 | Umbilical Herniorrhapy in Cirrhosis: Improved Outcomes with Elective Repair显示文摘 | Stephen H. Gray Catherine C. Vick Laura A. Graham Kelly R. Finan Leigh A. Neumayer Mary T. Hawn | 2008 | Journal of Gastrointestinal Surgery2008，，4： | 2 |
| 18 | The consumer quest for authenticity: The multiplicity of meanings within the MG subculture of consumption显示文摘 | Thomas W. Leigh Cara Peters Jeremy Shelton | 2006 | Journal of the Academy of Marketing Science2006，，： | 2 |
| 19 | Outcomes of Early- and Late-Identified Children at 3 Years of Age: Findings From a Prospective Population-Based Study显示文摘 | Teresa Y. C. Ching Harvey Dillon Vivienne Marnane Sanna Hou Julia Day Mark Seeto Kathryn Crowe Laura Street Jessica Thomson Patricia Van Buynder Vicky Zhang Angela Wong Lauren Burns Christopher Flynn Linda Cupples Robert S. C. Cowan Greg Leigh Jessica Sja | 2013 | Ear and Hearing2013，，5： | 2 |
| 20 | Cognitive load selectively interferes with utilitarian moral judgment显示文摘 | Joshua D. Greene Sylvia A. Morelli Kelly Lowenberg Leigh E. Nystrom Jonathan D. Cohen | 2007 | Cognition2007，，3： | 2 |
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