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| 1 | Electro-acupuncture to prevent prolonged postoperative ileus:A randomized clinical trial显示文摘AIM:To examine whether acupuncture can prevent prolonged postoperative ileus(PPOI)after intraperitoneal surgery for colon cancer. METHODS:Ninety patients were recruited from the Fudan University Cancer Hospital,Shanghai,China. After surgery,patients were randomized to receive acupuncture(once daily,starting on postoperative day 1, for up to six consecutive days)or usual care.PPOI was defined as an inability to pass flatus or have a bowel movement by 96 h after surgery.The main outcomes were time to first flatus,time to first bowel movement, and electrogastroenterography.Secondary outcomes were quality of life(QOL)measures,including pain, nausea,insomnia,abdominal distension/fullness,and sense of well-being. RESULTS:No significant differences in PPOI on day 4 (P=0.71)or QOL measures were found between the groups.There were also no group differences when the data were analyzed by examining those whose PPOI had resolved by day 5(P=0.69)or day 6(P= 0.88).No adverse events related to acupuncture were reported. CONCLUSION:Acupuncture did not prevent PPOI andwas not useful for treating PPOI once it had developed in this population. | M Kay Garcia Joseph S Chiang Bob Thornton J Lynn Palmer Jennifer McQuade Lorenzo Cohen | 2010 | World Journal of Gastroenterology2010，16，1： | 27 |
| 2 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 3 | Reproducibility of the diagnosis of dysplasia in Barrett esophagus: A reaffirmation显示文摘 | Elizabeth Montgomery Mary P Bronner John R Goldblum Joel K Greenson Marian M Haber John Hart Laura W Lamps Gregory Y Lauwers Audrey J Lazenby David N Lewin Marie E Robert Alicia Y Toledano Yu Shyr Kay Washington | 2001 | Human Pathology2001，，4： | 3 |
| 4 | Computed tomographic colonography versus colonoscopy for investigation of patients with symptoms suggestive of colorectal cancer (SIGGAR): a multicentre randomised trial显示文摘 | Wendy Atkin Edward Dadswell Kate Wooldrage Ines Kralj-Hans Christian von Wagner Rob Edwards Guiqing Yao Clive Kay David Burling Omar Faiz Julian Teare Richard J Lilford Dion Morton Jane Wardle Steve Halligan | 2013 | The Lancet2013，，： | 3 |
| 5 | Computed tomographic colonography versus barium enema for diagnosis of colorectal cancer or large polyps in symptomatic patients (SIGGAR): a multicentre randomised trial显示文摘 | Steve Halligan Kate Wooldrage Edward Dadswell Ines Kralj-Hans Christian von Wagner Rob Edwards Guiqing Yao Clive Kay David Burling Omar Faiz Julian Teare Richard J Lilford Dion Morton Jane Wardle Wendy Atkin | 2013 | The Lancet2013，，： | 2 |
| 6 | Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion显示文摘 | Philip N Newsome Ingolfur Johannessen Shelagh Boyle Evangelos Dalakas Karen A Mcaulay Kay Samuel Frances Rae Lesley Forrester Marc L Turner Peter C Hayes David J Harrison Wendy A Bickmore John N Plevris | 2003 | Gastroenterology2003，，7： | 2 |
| 7 | Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial显示文摘 | Robert J Motzer Bernard Escudier Stéphane Oudard Thomas E Hutson Camillo Porta Sergio Bracarda Viktor Grünwald John A Thompson Robert A Figlin Norbert Hollaender Gladys Urbanowitz William J Berg Andrea Kay David Lebwohl Alain Ravaud | 2008 | The Lancet2008，，9637： | 2 |
| 8 | Epidermal growth factor receptor inhibits colitis-associated cancer in mice显示文摘 | Dubé Philip E Yan Fang Punit Shivesh Girish Nandini McElroy Steven J Washington M Kay Polk D Brent | 2012 | EN2012，，8： | 2 |
| 9 | Physical properties of dewatered wastewater sludge for landfilling 显示文摘 | Koening A Kay J N Wan I M | 1996 | War Sci Tech1996，34，34： | 2 |
| 10 | Reducing probability of decision error using stochastic resonance 显示文摘 | S kay J Michels H Chen P Varshney | 2006 | IEEE Signal Processing letter2006，13，11： | 1 |
| 11 | Epothilones in the treatment of cancer 显示文摘 | Larkin J M Kaye S B | 2006 | Expert Opin Investig Drugs2006，15，6： | 1 |
| 12 | Operational requirements and issues for coilgun electromagnetic launchers显示文摘 | Kaye R J | 2005 | IEEE Trans on Magnetics2005，41，1： | 1 |
| 13 | Pulmonary aspergilloma:analysis of prognosis in relation to haemoptysis and survey of treatment显示文摘 | JEWKES J KAY P H PANETH M | 1983 | Thorax1983，38，8： | 1 |
| 14 | DNA replication licensing factors and aneuploidy are linked to tumor cell cycle state and clinical outcome in penile carcinoma显示文摘 | Kayes O J Loddo M Patel N | 2009 | Clin Cancer Res2009，15，23： | 1 |
| 15 | A new technique for measuring pulmonary edema显示文摘 | Noble WH Obdrzalek J Kay JC | 1973 | J Appl Physiol1973，34，4： | 1 |
| 16 | Attention deficit in Alzheimer's disease is not stimulated by an anticholinergic/antihistaminergic drug and is distinct from deficits in healthy aging显示文摘 | Oken B Kishiyama S Kaye J | 1994 | Neurology1994，44，2： | 1 |
| 17 | Application of Baylis-Hillman methodology in a novel synthesis of quino- line derivatives 显示文摘 | FAMILONI O B KAYE P T KLAAS P J | 1998 | Chemical Communications1998，，23： | 1 |
| 18 | Application of Taguchi's robust parameter design methodology for process improve- ment显示文摘 | Antony J Mazharsolook E Kaye M | 1996 | Quality World1996，，： | 1 |
| 19 | ACR/EULAR 2010 rheumatoid arthritis classification criteria显示文摘 | Kay J Upehurch K S | 2012 | Rheumatology(Oxford)2012，51，6： | 1 |
| 20 | A decision support tool based on QFD and PMEA for the selection of manufacturing automation technologies 显示文摘 | Almannai B Greenough R Kay J | 2008 | Robotics and Computer-Integrated Manufacturing2008，24，4： | 1 |
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