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62篇 您的检索式:作者名="Reiman EM"
    题名 作者 年代 出处 被引量
1美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) 2012中华神经科杂志2012,45,5:22
2Longitudinal changes in cognition and behavior in asymptomatic carriers of the APOEε4 allele显示文摘 Reiman EM Osbome D 2004Neurology2004,62,:1
3Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease显示文摘Reiman EM Chen K Liu X 0,,16:1
4Alzheimer's disease and other dementias : advances in 2013 显示文摘Reiman EM 2014Lancet Neurol2014,13,:1
5Tracking Alzheimer's disease in transgenic mice using fluorodeoxyglucose autoradiography显示文摘Reiman EM Uecker A Gonzalez-Lima F 2000Neuroreport2000,11,5:1
6Enhanced detection of focal brain responses using intersubject averaging and change-distribution analysis of subtracted PET images显示文摘Fox PT Mintun MA Reiman EM 1988Journal of Cerebral Blood Flow and Metabolism1988,8,5:1
7Higher serum total cholesterol levels in late middle age are associated with glucose hypometabolism in brain regions affected by Alzheimer's disease and normal aging显示文摘Reiman EM Chen K Langbaum JB 2010Neuroimage2010,49,1:1
8Fibril ar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease显示文摘Reiman EM Chen K Liu X 0,,:1
9Neural correlates of heart rate variability during emotion 显示文摘Lane RD McRae K Reiman EM 2009NeuroImage2009,44,:1
10Neural correlates of heart rate variability during emotion显示文摘Lane RD McRae K Reiman EM 2009NeuroImage2009,,:1
11Alzheimer's disease and other dementias:advances in 2013显示文摘Reiman EM 2014Lancet Neurol2014,13,:1
12Cognitive performance in older women relative to ApoE-epsilon4 genotype and aerobic fitness显示文摘Etnier JL Caselli RJ Reiman EM 0,,01:1
13Functional imaging of an illusion of pain显示文摘Craig AD Reiman EM Evans A 1996Nature1996,384,6606:1
14The role of biomarkers in clinical trials for Alzheimer's disease 显示文摘Thai LJ Kantarci K Reiman EM 2006Alzheimer Dis Assoc Disord2006,20,1:1
15Hippocampal Volumes in Cognitively Normal Persons at Genetic Risk for Alzheimer's Disease显示文摘Reiman EM Uecker A Caselli RJ 1998Ann Neurol1998,44,2:1
16Neuroanatomical correlates of pleasant and unpleasant emotion显示文摘Lane RD Reiman EM Bradley MM 1997Neumpsychologia1997,35,11:1
17Alexander linking functional and structural brain images with multivariate network analyses: a novel application of the partial least square method显示文摘Chen KW Reiman EM Huan ZD 2009Neurolmage2009,47,2:1
18Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease 显示文摘Reiman EM Chen K Liu X 2009Proc Natl Acad Sci USA2009,106,16:1
19Alzheimer's disease and other dementias: advances in 2013 显示文摘Reiman EM 2014Lancet Neurol2014,13,1:1
20Evidence for an association between KIBRA and late-onset Alzheimer's disease显示文摘Corneveaux JJ Liang WS Reiman EM 2010Neurobiol Aging2010,31,:1
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