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| 1 | 小儿腹腔镜阑尾切除术的临床评价显示文摘目的 评价小儿腹腔镜阑尾切除术 (laparoscopicappendectomy ,LA)的效果。 方法 对比分析LA组 (n =89)和开腹阑尾切除术 (openappendectomy,OA)组 (n =90 )的手术效果、住院时间、费用支出和患者满意程度。 结果 LA组较OA组手术时间显著延长 [(5 7± 2 )minvs (43± 1)min ,t=6 2 82 ,P =0 0 0 0 ],总医疗费用显著降低 [(15 2 91± 4 99)元vs.(174 4 2±5 4 4 )元 ,t=- 2 912 ,P =0 0 0 4 ],住院时间显著缩短 [(2 9± 0 2 )dvs.(3 6± 0 2 )d ,t=- 2 4 75 ,P =0 0 14 ],两组手术并发症发生率和病人满意度调查无明显差别 (χ2 =0 119,P =0 730 ;χ2 =0 4 35 ,P =0 5 0 9)。 结论 两种术式同样有效 ,LA不增加医疗费用 ,LA微创特点和探查腹腔更具优越性 ,提倡用于小儿阑尾炎。 | 徐德利 Chris Kimber John M Hutson | 2004 | 中国微创外科杂志2004，4，2： | 5 |
| 2 | 新型光室结构的主流式NDIR呼吸CO2监测系统显示文摘针对主流式非分散红外(NDIR)呼吸CO2监测系统灵敏度及信噪比低下的问题,提出利用复合抛物面聚光器(CPC)提升监测系统性能的方法。利用ZEMAX模拟光室并优化CPC和常用的圆管聚光器以及锥形聚光器,采用单光源双光路的主流式一体化方法进行监测系统的气室设计,以STM32F100为主控芯片实现硬件系统控制,对具有不同光室结构的监测系统进行CO2浓度标定和实时人体呼吸检测实验,获取其CO2浓度与系统输出信号的对应关系和CO2波形图。结果表明,CPC光室其模拟光学效率为4.3%,比常用的聚光器最高可提升89.77倍;装有CPC的监测系统其灵敏度与信噪比为8.9407、24.65,比装有常用聚光器的系统的灵敏度最高可提升3.811倍、信噪比提升1.926倍;并且安装CPC的系统运行稳定,响应快,能够实时的反应出被测者的呼吸CO2波形图。 | 熊涛 高明(指导) Des Gibson David Hutson | 2020 | 红外与激光工程2020，49，6： | 4 |
| 3 | Single-Incision Laparoscopic Cholecystectomy Versus Conventional Laparoscopic Cholecystectomy: Meta-analysis and Systematic Review of Randomized Controlled Trials显示文摘 | Muhammad S. Sajid Nikhil Ladwa Lorain Kalra Kristian K. Hutson Krishna K. Singh Mazin Sayegh | 2012 | World Journal of Surgery2012，，11： | 3 |
| 4 | Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial显示文摘 | Brian I Rini Bernard Escudier Piotr Tomczak Andrey Kaprin Cezary Szczylik Thomas E Hutson M Dror Michaelson Vera A Gorbunova Martin E Gore Igor G Rusakov Sylvie Negrier Yen-Chuan Ou Daniel Castellano Ho Yeong Lim Hirotsugu Uemura Jamal Tarazi David Cella | 2011 | The Lancet . 2011 (9807)2011，，9807： | 2 |
| 5 | Axitinib versus sorafenib as first-line therapy in patients with metastatic renal-cell carcinoma: a randomised open-label phase 3 trial显示文摘 | Thomas E Hutson Vladimir Lesovoy Salman Al-Shukri Viktor P Stus Oleg N Lipatov Angel H Bair Brad Rosbrook Connie Chen Sinil Kim Nicholas J Vogelzang | 2013 | Lancet Oncology2013，，13： | 2 |
| 6 | Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial显示文摘 | Brian I Rini Bernard Escudier Piotr Tomczak Andrey Kaprin Cezary Szczylik Thomas E Hutson M Dror Michaelson Vera A Gorbunova Martin E Gore Igor G Rusakov Sylvie Negrier Yen-Chuan Ou Daniel Castellano Ho Yeong Lim Hirotsugu Uemura Jamal Tarazi David Cella | 2011 | The Lancet2011，，9807： | 2 |
| 7 | Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial显示文摘 | Robert J Motzer Bernard Escudier Stéphane Oudard Thomas E Hutson Camillo Porta Sergio Bracarda Viktor Grünwald John A Thompson Robert A Figlin Norbert Hollaender Gladys Urbanowitz William J Berg Andrea Kay David Lebwohl Alain Ravaud | 2008 | The Lancet2008，，9637： | 2 |
| 8 | Sunitinib versus interferon alfa in metastatic renal cell carcinoma 显示文摘 | Motzer R J Hutson TE Tomczak P | 2007 | N Engl J Med2007，356，2： | 1 |
| 9 | Bone scintigraphy in the assessment of spondylolysis in patients attending a sports injury clinic显示文摘 | Hutson MA Wastie ML | 1988 | Clin Radiol1988，39，3： | 1 |
| 10 | Matrix Gla p rotein (MGP) and bone morphogenetic proteion -2 in aortic calcified lesions of aging rats显示文摘 | Hutson SM | 2003 | Thromb Haemost2003，1，1： | 1 |
| 11 | Early and late-phase bronchconstriction allergen challenge of nonanesthetized guinea pigs 显示文摘 | Hutson PA Church MK Clay YP | 1988 | Am Rev Respir Dis1988，137，3： | 1 |
| 12 | Purification and characterization of a lipophilic factor from testicular macrophages that stimulates testosterone production by Leydig cells显示文摘 | Hutson JC Garner CW Doris PA | 1996 | J Androl1996，17，5： | 1 |
| 13 | Clinical and immunologic effects of subcutaneously administered interleukin-12 and interferon alfa-2b:phase Ⅰ trial of patients with metastatic renal cell carcinoma or malignant melanoma显示文摘 | Alatrash G Hutson TE Molto L | 2004 | J Clin Oncol2004，22，14： | 1 |
| 14 | A phase Ⅱ study of GW786034 using a randomized discontinuation design in patients with locally recurrent or metastatic clear-cell renal cell carcinoma 显示文摘 | Hutson TE Bukowski RM | 2006 | Clin Genitourin Cancer2006，4，4： | 1 |
| 15 | Sunitinib versus interferon alfa in metastatic renal cell carcinoma 显示文摘 | Motzer R J Hutson TE Tomczak P | 2007 | N Engl J Med2007，356，11： | 1 |
| 16 | Postcholecystemy pain syn-drome: Pathogypsiology of abdominal pain in sphincter of Oddi type Ⅲ显示文摘 | Desautel SG Slivka A Hutson WR | 1999 | Gasrtroenterology1999，116，4： | 1 |
| 17 | Evolutionary traceresidues in Noroviruses : importance in receptor binding, antigenicity, virion assembly, and strain diversity 显示文摘 | Chakravarty S Hutson A M Estes M K | 2005 | J Virol2005，79，1： | 1 |
| 18 | Sunitinib versus inter- feron alpha in metastatic renal-cell carcinoma显示文摘 | Motzer RJ Hutson TE Tomezak P | 2007 | N Engl J Med2007，356，2： | 1 |
| 19 | Persulfate oxidation regeneration of granular activated carbon: Reversible impacts on sorption behavior 显示文摘 | HUTSON A KO S HULING S G | 2012 | Chemosphere2012，89，10： | 1 |
| 20 | Diagnosis and management of infection after tibial intramedul ary nailing显示文摘 | Zych GA Hutson JJ Jr | | 0，，315： | 1 |
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