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541篇 您的检索式:作者名="Jaye M"
    题名 作者 年代 出处 被引量
1Significant association between ABO blood group and pancreatic cancer显示文摘AIM:To evaluate whether the ABO blood group is related to pancreatic cancer risk in the general population of the United States.METHODS:Using the University of Pittsburgh's clinicalpancreatic cancer registry,the blood donor database from our local blood bank (Central Blood Bank),and the blood product recipient database from the regional transfusion service (Centralized Transfusion Service) in Pittsburgh,Pennsylvania,we identified 274 pancreatic cancer patients with previously determined serological ABO blood group information.The ABO blood group frequency was compared between these patients and 708842 individual,community-based blood donors who had made donations to Pittsburgh's Central Blood Bank between 1979 and 2009.RESULTS:The frequency of blood group A was statistically significantly higher amongst pancreatic cancer patients compared to its frequency amongst the regional blood donors [47.63% vs 39.10%,odds ratio (OR)=1.43,P=0.004].Conversely,the frequency of blood group O was significantly lower amongst pancreatic cancer patients relative to the community blood donors (32.12% vs 43.99%,OR=0.60,P=0.00007).There were limited blood group B (n=38) and AB (n=17) pancreatic cancer patients;the overall P trend value comparing patient to donor blood groups was 0.001.CONCLUSION:The ABO blood group is associated with pancreatic cancer risk.Future studies should examine the mechanism linking pancreatic cancer risk to ABO blood group.Julia B Greer Mark H Yazer Jay S Raval M Michael Barmada Randall E Brand David C Whitcomb 2010World Journal of Gastroenterology2010,16,44:10
2Standard forward-viewing colonoscopy versus full-spectrum endoscopy: an international, multicentre, randomised, tandem colonoscopy trial显示文摘Ian M Gralnek Peter D Siersema Zamir Halpern Ori Segol Alaa Melhem Alain Suissa Erwin Santo Alan Sloyer Jay Fenster Leon M G Moons Vincent K Dik Ralph B D’Agostino Douglas K Rex 2014Lancet Oncology2014,,3:6
3Comparison of choroidal vessel thickness in children and adult eyes by enhanced-depth imaging optical coherence tomography imaging显示文摘AIM: To evaluate choroidal thickness, medium choroidal vessel thickness(MCVT) and large choroidal vessel thickness(LCVT) in normal children and adult subjects.METHODS: Manual measurements of subfoveal choroidal thickness(SFCT), MCVT and LCVT at subfoveal and 750 μm nasal and temporal to fovea locations were completed on enhanced-depth imaging optical coherence tomography(EDI-OCT) scans of normal children and adult subjects.RESULTS: Fifty adult and fifty-seven child subjects were included in the study(including 80 adult and 103 child eyes). Mean(±SD) SFCT of adult and children eyes in the study was 309.3±95.7 μm and 279.3±50.4 μm respectively. SFCT and subfoveal MCVT in adult eyes were significantly more than children(P=0.01 and P≤0.0001 respectively).CONCLUSION: There is choroidal thickening with associated thickening of medium choroidal vessels in adults, suggesting that there is alteration in choroidal vasculature with ageing.Daren Hanumunthadu Jorge Ruiz-Medrano Sunila Dumpala Ayesha Jabeen Asiya Jabeen Abhilash Goud JoséM Ruiz-Moreno Jay Chhablani 2018International Journal of Ophthalmology(English edition)2018,11,4:6
4Clinical application of concentrated bone marrow aspirate in orthopaedics:A systematic review显示文摘AIM To examine the evidence behind the use of concentrated bone marrow aspirate(c BMA) in cartilage, bone, and tendon repair; establish proof of concept for the use of cB MA in these biologic environments; and provide the level and quality of evidence substantiating the use of cB MA in the clinical setting.METHODS We conducted a systematic review according to PRISMA guidelines. EMBASE, MEDLINE, and Web of Knowledge databases were screened for the use of cB MA in the repair of cartilage, bone, and tendon repair. We extracted data on tissue type, cB MA preparation, cB MA concentration, study methods, outcomes, and level of evidence and reported the results in tables and text.RESULTS A total of 36 studies met inclusion/exclusion criteria and were included in this review. Thirty-one of 36(86%) studies reported the method of centrifugation and preparation of cB MA with 15(42%) studies reporting either a cell concentration or an increase from baseline. Variation of c BMA application was seen amongst the studies evaluated. Twenty-one of 36(58%) were level of evidence Ⅳ, 12/36(33%) were level of evidence Ⅲ, and 3/36(8%) were level of evidence Ⅱ. Studies evaluated full thickness chondral lesions(7 studies), osteochondral lesions(10 studies), osteoarthritis(5 studies), nonunion or fracture(9 studies), or tendon injuries(5 studies). Significant clinical improvement with the presence of hyaline-like values and lower incidence of fibrocartilage on T2 mapping was found in patients receiving cB MA in the treatment of cartilaginous lesions. Bone consolidation and time to bone union was improved in patients receiving cB MA. Enhanced healingrates, improved quality of the repair surface on ultrasound and magnetic resonance imaging, and a decreased risk of re-rupture was demonstrated in patients receiving cB MA as an adjunctive treatment in tendon repair. CONCLUSION The current literature demonstrates the potential benefits of utilizing c BMA for the repair of cartilaginous lesions, bony defects, and tendon injuries in the clinical setting. This study also demonstrates discrepancies between the literature with regards to various methods of centrifugation, variable cell count concentrations, and lack of standardized outcome measures. Future studies should attempt to examine the integral factors necessary for tissue regeneration and renewal including stem cells, growth factors and a biologic scaffold.Arianna L Gianakos Li Sun Jay N Patel Donald M Adams Frank A Liporace 2017World Journal of Orthopedics2017,8,6:5
5Multipurpose use of the ‘bear claw’ (over‐the‐scope‐clip system) to treat endoluminal gastrointestinal disorders显示文摘Klaus M?nkemüller Shajan Peter Jay Toshniwal Daniel Popa Marzena Zabielski Richard D. Stahl Jayapal Ramesh C. Mel Wilcox 2014Digestive Endoscopy2014,,3:4
6Endoscopist's approach to nutrition in the patient with pancreatitis显示文摘Nutritional therapy has an important role in the management of patient with severe acute pancreatitis.This article reviews the endoscopist's approach to manage nutrition in such cases.Enteral feeding has been clearly validated as the preferred route of feeding,and should be started early on admission.Parenteral nutrition should be reserved for patients with contraindications to enteral feeding such as small bowel obstruction.Moreover,nasogastric feeding is safe and as effective as nasojejunal feeding.If a prolonged course of enteral feeding(>30d) is required,endoscopic placement of feeding gastrostomy or jejunostomy tubes should be considered.Shahzad Iqbal Jay P Babich James H Grendell David M Friedel 2012World Journal of Gastrointestinal Endoscopy2012,4,12:4
7An update on the diagnosis of gastroenteropancreatic neuroendocrine neoplasms显示文摘Gastroenteropancreatic neuroendocrine neoplasms(GEP-NENs)arise from neuroendocrine cells found throughout the gastrointestinal tract and islet cells of the pancreas.The incidence and prevalence of GEP-NENs have been increasing each year due to higher awareness,improved diagnostic modalities,and increased incidental detection on cross-sectional imaging and endoscopy for cancer screening and other conditions and symptoms.GEP-NENs are a heterogeneous group of tumors and have a wide range in clinical presentation,histopathologic features,and molecular biology.Clinical presentation most commonly depends on whether the GEP-NEN secretes an active hormone.The World Health Organization recently updated the classification of GEP-NENs to introduce a distinction between high-grade neuroendocrine tumors and neuroendocrine carcinomas,which can be identified using histology and molecular studies and are more aggressive with a worse prognosis compared to high-grade neuroendocrine tumors.As our understanding of the biology of GEP-NENs has grown,new and improved diagnostic modalities can be developed and optimized.Here,we discuss clinical features and updates in diagnosis,including histopathological analysis,biomarkers,molecular techniques,and radiology of GEP-NENs.We review established diagnostic tests and discuss promising novel diagnostic tests that are currently in development or require further investigation and validation prior to broad utilization in patient care.Jiayun M Fang Jay Li Jiaqi Shi 2022World Journal of Gastroenterology2022,28,10:3
8Improvements to NOAA’s Historical Merged Land-Ocean Surface Temperature Analysis (1880-2006)显示文摘Smith Thomas M Reynolds Richard W Peterson Thomas C Lawrimore Jay Journal of Climate0,,:3
9Endoscopic approach to pancreatic pseudocysts:An American perspective显示文摘Pancreatic pseudocysts,abscesses,and walled-off pancreatic necrosis are types of pancreatic fluid colle-ctions that arise as a consequence of pancreatic injury.Pain,early satiety,biliary obstruction,and infection are all indications for drainage.Percutaneous-radiologic drainage,surgical drainage,and endoscopic drainage are the three traditional approaches to the drainage of pancreatic pseudocysts.The endoscopic approach to pancreatic pseudocysts has evolved over the past thirty years and endoscopists are often capable of draining these collections.In experienced centers endoscopic ultrasound-guided endoscopic drainage avoids complications related to percutaneous drainage and is less invasive than surgery.Jay P Babich David M Friedel 2010World Journal of Gastrointestinal Endoscopy2010,2,3:2
10Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study显示文摘Pierre Fenaux Ghulam J Mufti Eva Hellstrom-Lindberg Valeria Santini Carlo Finelli Aristoteles Giagounidis Robert Schoch Norbert Gattermann Guillermo Sanz Alan List Steven D Gore John F Seymour John M Bennett John Byrd Jay Backstrom Linda Zimmerman David M 2009Lancet Oncology2009,,:2
11Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db / db Mice显示文摘Hong Chen Olga Charlat Louis A Tartaglia Elizabeth A Woolf Xun Weng Stephen J Ellis Nathan D Lakey Janice Culpepper Karen J More Roger E Breitbart Geoffrey M Duyk Robert I Tepper Jay P Morgenstern 1996Cell1996,,3:2
12Hepatitis C and renal disease: an update 1 1 Summary of a workshop held October 21 to 22, 2002, in the Lister Hill Auditorium, The National Institutes of Health, Bethesda, MD.显示文摘Catherine M Meyers Leonard B Seeff Catherine O Stehman-Breen Jay H Hoofnagle 2003American Journal of Kidney Diseases2003,,4:2
13A novel endothelial-derived lipase that modulatesHDL metabolism显示文摘Jaye M Lynch Kj Krawiec J 1999Nat Genet1999,21,4:1
14Plasticity at hippocampal to prefrontal cortexsynapses is impaired by loss of dopamine and stress: importance for psychiatric diseases显示文摘JAY TM ROCHER C HOTTE M 2009Neurotox Res2009,6,3:1
15Lung myeloperoxidase as a measure of pulmonary leukostasis in rabbits显示文摘Goldblum S E Wu K M Jay M 1985J Appl Physiol1985,59,:1
16Gizard formation and the role of Bapxl显示文摘Corinne N Lewis C M Jay C C 2001Develop Biol2001,231,1:1
17A Tabu Search Heuristic Procedure for the Fixed Charge Transportation Problem 显示文摘Sun M H Jay E A 1998European Journal of Operation Research1998,106,3:1
18Arabidopsis CAM7 and HY5 Physically Interact and Directly Bind to the HY5 Promoter to Regulate Its Expression and Thereby Promote Photomorpho- genesis显示文摘Nazial A Jay M Dhirodatta S 2014PlantCell2014,26,3:1
19A novel endothelial-derived lipase that modulates HDI metabolism显示文摘 Lynch KJ Krawiec J 1999NatGenet1999,21,4:1
20Knowledge Discovery in Database显示文摘M Jay Norton 1999Library Trends1999,48,1:1
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