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| 1 | Standard forward-viewing colonoscopy versus full-spectrum endoscopy: an international, multicentre, randomised, tandem colonoscopy trial显示文摘 | Ian M Gralnek Peter D Siersema Zamir Halpern Ori Segol Alaa Melhem Alain Suissa Erwin Santo Alan Sloyer Jay Fenster Leon M G Moons Vincent K Dik Ralph B D’Agostino Douglas K Rex | 2014 | Lancet Oncology2014，，3： | 6 |
| 2 | Endoscopic innovations to increase the adenoma detection rate during colonoscopy显示文摘Up to a quarter of polyps and adenomas are missed during colonoscopy due to poor visualization behind folds and the inner curves of flexures,and the presence of flat lesions that are difficult to detect.These numbers may however be conservative because they mainly come from back-to-back studies performed with standard colonoscopes,which are unable to visualize the entire mucosal surface.In the past several years,new endoscopic techniques have been introduced to improve the detection of polyps and adenomas.The introduction of high definition colonoscopes and visual image enhancement technologies have been suggested to lead to better recognition of flat and small lesions,but the absolute increase in diagnostic yield seems limited.Cap assisted colonoscopy and water-exchange colonoscopy are methods to facilitate cecal intubation and increase patients comfort,but show only a marginal or no benefit on polyp and adenoma detection.Retroflexion is routinely used in the rectum for the inspection of the dentate line,but withdrawal in retroflexion in the colon is in general not recommended due to the risk of perforation.In contrast,colonoscopy with the Third-Eye Retroscope?may result in considerable lower miss rates compared to standard colonoscopy,but this technique is not practical in case of polypectomy and is more time consuming.The recently introduced Full Spectrum Endoscopy?colonoscopes maintains the technical capabilities of standard colonoscopes and provides a much wider view of 330 degrees compared to the 170 degrees with standard colonoscopes.Remarkable lower adenoma miss rates with this new technique were recently demonstrated in the first randomized study.Nonetheless,more studies are required to determine the exact additional diagnostic yield in clinical practice.Optimizing the efficacy of colorectal cancer screening and surveillance requires high definition colonoscopes with improved virtual chromoendoscopy technology that visualize the whole colon mucosa while maintaining optimal washing,suction and therapeutic capabilities,and keeping the procedural time as low and patient discomfort as optimal as possible. | Vincent K Dik Leon MG Moons Peter D Siersema | 2014 | World Journal of Gastroenterology2014，20，9： | 6 |
| 3 | Case 01-2017-Primary vitreoretinal lymphoma(PVRL):report of a case and update of literature from 1942 to 2016显示文摘Primary vitreoretinal lymphoma (PVRL), as a subset of primary central nervous system lymphoma (PCNSL), is a rare and fatal ocular malignancy. Most PVRL masquerades as chronic posterior uveitis, which makes the clinical diagnosis challenging. Vitreous cells, subretinal lesions and imaging techniques are essential for clinical diagnosis. Importantly, cytopathology/histopathology identification of malignant cells is the gold standard for the diagnosis of PVRL. In addition, molecular detection of immunoglobulin heavy chain (IgH) or T cell receptor (TCR) gene rearrangements, immunophenotyping for cell markers, and cytokine analysis of interleukine-10 elevation are often used as adjunct procedures. Current management of PVRL involves local radiation, intravitreal chemotherapy (methotrexate and rituximab), with or without systemic chemotherapy depending on the involvement of non-ocular tissues. In cases with concomitant PCNSL, systemic high-dose methotrexate/rituximab based therapy in conjunction with local therapy, whole brain radiotherapy and/or autologous stem cell transplantation is considered. Although PVRL normally responds well to initial treatment, high rates of relapse and CNS involvement usually lead to poor prognosis and limited survival. A professional team of medical experts in ophthalmologists, ocular pathologists, neuro-oncologists and hemato-oncologists is essential for optimizing patient management. | Yujuan Wang Dik SCheung Chi-Chao Chan | 2017 | Annals of Eye Science2017，，1： | 3 |
| 4 | ENETS Consensus Guidelines for the Management of Patients with Gastroduodenal Neoplasms显示文摘 | Delle Fave Gianfranco Kwekkeboom Dik J Van Cutsem Erik Rindi Guido Kos-kudla Beata Knigge Ulrich Sasano Hironobu Tomassetti Paola Salazar Ramon Ruszniewski Philippe | 2012 | Neuroendocrinology2012，，2： | 3 |
| 5 | WONCA研究论文摘要汇编--门诊医疗不公平现象及社会经济状况与呼吸病住院的关系:加拿大某城市人口学研究显示文摘目的由于门诊照护敏感性,原本可门诊治疗的病症,尤其是慢性阻塞性肺疾病(COPD)和哮喘患者,低社会经济状况的个体住院率要更高。此研究对患者人口学、门诊照护利用或医生特征的差异能否用来解释可避免住院治疗的这种差异进行了调查。方法提取加拿大马尼托巴省温尼伯市的住院数据,将年龄18~70岁COPD或哮喘阻塞性呼吸道病患者纳入研究。用家庭均收入法,将患者分入人口普查收入五等分位。控制患者人口学(社会经济状况、年龄、性别及并发症)、门诊照护利用情况(流感疫苗接种和专科医生转诊)以及患者家庭医生的特征(如收费机制、性别和从医年限)协变量后,完成多变量逻辑回归分析,以确定社会经济状况与阻塞性呼吸道疾病住院风险变化有着怎样的关联。 | Trachtenberg AJ Dik N Chateau D 周淑新 | 2014 | 中国全科医学2014，17，36： | 2 |
| 6 | A new statistic and practical guidelines for nonparametric Granger causality testing显示文摘 | Cees Diks Valentyn Panchenko | 2006 | Journal of Economic Dynamics and Control2006，，9： | 2 |
| 7 | Bladder-sphincter dysfunction in myelomeningocele 显示文摘 | van Gool JD Dik P de Jong TP | 2001 | Eur J Pediatr2001，160，7： | 1 |
| 8 | Comparison of three biological control agents against cucumber powdery mildew(Sphaerothecafuliginea)in semicommercial-scale glasshouse trials显示文摘 | Dik A J Verhaar M A Bérlanger R R | | 0，，： | 1 |
| 9 | Localization and potential role of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 and-2 in different phases of bronchopulmonary dysplasia 显示文摘 | Dik WA De Krejger RR Bonekamp L | 2001 | Pediatr Res2001，50，6： | 1 |
| 10 | Toolbox for the modification of lecithin headgroup 显示文摘 | DOIG S D DIKS R M M | 2003 | Eur J Lipid Sci Technol2003，105，7： | 1 |
| 11 | Laparoscopy-assisted anorectal pull-through in anorectal malformations: a reap- praisal显示文摘 | Van der Zee DC Dik P Beek FJ | 2013 | World J Surg2013，37，8： | 1 |
| 12 | Calling and vocation at work definitionsand prospects for research and practice显示文摘 | Dik B J Duffy R D | 2009 | The CounselingPsychologist2009，37，3： | 1 |
| 13 | Localization and potential role of matrix metal-loproteinase-1 and tissue inhibitors of metalloproteinase-1 and-2 in different phases of bronchopulmonary dysplasia显示文摘 | Dik WA De Krijger RR Bonekamp L | 2001 | Pediatr Res2001，50，6： | 1 |
| 14 | Developmentand validation of the calling and vocation questionnaire(CVQ) and brief calling scale (BCS) 显示文摘 | Dik B J Eldridge B M Steger M Fs | 2012 | Journal of CareerAssessment2012，20，3： | 1 |
| 15 | A New Statistics and Practical Guidelines for Nonparametrie Granger Causality Testing 显示文摘 | Cees Diks Valentyn Panchen | 2006 | Journal of Economic Dynamics and Control2006，，30： | 1 |
| 16 | Sling suspension of the bladder neck for pediatric urinary incontinence 显示文摘 | Chrzan R Dik P Klijn AJ | 2009 | J Pediatr Urol2009，5，2： | 1 |
| 17 | A comparison of on-pump and of-pump coronary by pass surgery in low risk patients显示文摘 | Nathoe NM Dik DV Jansen EWL | 2013 | N Engl J Med2013，104，348： | 1 |
| 18 | Serum inflamma- tory proteins and cognitive decline in older persons 显示文摘 | Dik M G Jonker C Hack C E | 2005 | Neurology2005，64，6： | 1 |
| 19 | The course of cognitive decline in older persons:results from the longitudinal aging study Amsterdam显示文摘 | Comijs HC Dik MG Deeg DJ | 2004 | Dement Geriatr Cogn Disord2004，17，： | 1 |
| 20 | Depression is associated with decreased 25-hydroxyvitamin D and increased parathyroid hormone levels in older adults 显示文摘 | Hoogendijk WJ Lips P Dik MG | 2008 | Arch Gen Psychiatry2008，65，5： | 1 |
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